Advertisement
Research ArticleInflammation, Immunopharmacology, and Asthma

Pharmacologic Profile of OC000459, a Potent, Selective, and Orally Active D Prostanoid Receptor 2 Antagonist That Inhibits Mast Cell-Dependent Activation of T Helper 2 Lymphocytes and Eosinophils

Roy Pettipher, Shân L. Vinall, Luzheng Xue, Graham Speight, Elizabeth R. Townsend, Lucien Gazi, Cliff J. Whelan, Richard E. Armer, Mark A. Payton and Michael G. Hunter
Journal of Pharmacology and Experimental Therapeutics February 2012, 340 (2) 473-482; DOI: https://doi.org/10.1124/jpet.111.187203

Article Information

vol. 340 no. 2 473-482
DOI 
https://doi.org/10.1124/jpet.111.187203
PubMed 
22106101
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 25, 2011
  • Accepted November 16, 2011
  • Published online January 19, 2012.

Article Versions

Copyright & Usage 
Copyright © 2012 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Roy Pettipher,
  2. Shân L. Vinall,
  3. Luzheng Xue,
  4. Graham Speight,
  5. Elizabeth R. Townsend,
  6. Lucien Gazi,
  7. Cliff J. Whelan,
  8. Richard E. Armer,
  9. Mark A. Payton and
  10. Michael G. Hunter
  1. Oxagen Ltd, Abingdon, Oxon, United Kingdom (R.P., S.L.V., L.X., G.S., E.R.T., L.G., R.E.A, M.A.P., M.G.H.); and Department of Life Sciences, University of Hertfordshire, Hatfield, Herts, United Kingdom (C.J.W.)
  1. Address correspondence to:
    Roy Pettipher, Oxagen Ltd, 91 Milton Park, Abingdon, Oxon, OX14 4RY, United Kingdom. E-mail: r.pettipher{at}oxagen.co.uk
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: November 2011 to January 2023

AbstractFullPdf
Nov 20112020102
Dec 2011910116
Jan 201234421135
Feb 20122912066
Mar 20121742056
Apr 20121582642
May 20121652043
Jun 20121441447
Jul 20121182139
Aug 20121401636
Sep 2012911230
Oct 20121102947
Nov 2012831423
Dec 201264730
Jan 2013461320
Feb 2013532341
Mar 2013472933
Apr 2013823547
May 2013543128
Jun 2013512018
Jul 2013332514
Aug 2013242323
Sep 201342711
Oct 2013351222
Nov 2013282917
Dec 2013252733
Jan 2014202422
Feb 2014222120
Mar 2014153223
Apr 2014242522
May 2014232322
Jun 2014241512
Jul 2014231913
Aug 2014311615
Sep 20144189
Oct 201445610
Nov 2014271818
Dec 201413138
Jan 2015311216
Feb 2015281514
Mar 2015311814
Apr 201510108
May 2015252112
Jun 201513179
Jul 2015162424
Aug 2015141010
Sep 2015241718
Oct 2015121816
Nov 2015261819
Dec 2015352010
Jan 2016372118
Feb 201618815
Mar 2016322638
Apr 2016301218
May 2016251521
Jun 2016261413
Jul 2016381120
Aug 2016442332
Sep 2016251024
Oct 201652514
Nov 2016203420
Dec 201682114
Jan 201742719
Feb 201722620
Mar 201714313
Apr 201712712
May 201702911
Jun 201723217
Jul 201752412
Aug 20170142
Sep 201703211
Oct 20172219
Nov 201704016
Dec 20178203
Jan 201814514
Feb 201812415
Mar 201832113
Apr 201834026
May 201803715
Jun 201812624
Jul 20184189
Aug 20180196
Sep 201842110
Oct 20180315
Nov 201862714
Dec 20182452
Jan 20192822
Feb 201954323
Mar 20192861
Apr 20192633
May 201913122
Jun 20191956
Jul 201928159
Aug 20192726
Sep 20193044
Oct 20192243
Nov 20193421
Dec 20193962
Jan 202022116
Feb 20201654
Mar 20201241
Apr 20201474
May 2020431
Jun 2020941
Jul 2020641012
Aug 20201456
Sep 20203364
Oct 20202363
Nov 20204784
Dec 20203224
Jan 20214479
Feb 20212676
Mar 20214575
Apr 20213561
May 20212966
Jun 20212492
Jul 20212765
Aug 202130139
Sep 20211920
Oct 20212611
Nov 20213024
Dec 20212832
Jan 202238720
Feb 20222142
Mar 2022812
Apr 20222716
May 20221733
Jun 20223121
Jul 20222920
Aug 20222739
Sep 202221410
Oct 20224042
Nov 20221622
Dec 20224026
Jan 20233750

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleInflammation, Immunopharmacology, and Asthma

Pharmacological Profile of the Novel DP2 Antagonist OC000459

Roy Pettipher, Shân L. Vinall, Luzheng Xue, Graham Speight, Elizabeth R. Townsend, Lucien Gazi, Cliff J. Whelan, Richard E. Armer, Mark A. Payton and Michael G. Hunter
Journal of Pharmacology and Experimental Therapeutics February 1, 2012, 340 (2) 473-482; DOI: https://doi.org/10.1124/jpet.111.187203
del.icio.us logo Digg logo Reddit logo Twitter logo Facebook logo Google logo Mendeley logo

Jump to section

Advertisement