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Index by author

November 01, 2011; Volume 339,Issue 2

A

  1. Abbruscato, Thomas J.

    1. Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
      Li Yang, Kaushik Shah, Hezhen Wang, Vardan T. Karamyan and Thomas J. Abbruscato
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 499-508; DOI: https://doi.org/10.1124/jpet.111.184127

  2. Abell, Lynn M.

    1. Dissecting the Activation of Thienopyridines by Cytochromes P450 Using a Pharmacodynamic Assay In Vitro
      Lynn M. Abell and Eddie C.-K. Liu
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 589-596; DOI: https://doi.org/10.1124/jpet.111.184895

  3. Abraham, Robert T.

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  4. Adam, Bao-Ling

    1. Effects of Chlorpyrifos and Chlorpyrifos-Oxon on the Dynamics and Movement of Mitochondria in Rat Cortical Neurons
      Mary-Louise Middlemore-Risher, Bao-Ling Adam, Nevin A. Lambert and Alvin V. Terry
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 341-349; DOI: https://doi.org/10.1124/jpet.111.184762

  5. Aguayo, Luis G.

    1. Activated G Protein αs Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors
      Gonzalo E. Yévenes, Gustavo Moraga-Cid, Ximena Romo and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 386-393; DOI: https://doi.org/10.1124/jpet.111.184408

  6. Ahluwalia, Amrita

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  7. Akiba, Yasutada

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

  8. Allen, Scott C.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  9. Alvarez, John

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  10. Andrenyak, David M.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  11. Ao, Ying

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  12. Apfeldorfer, Coralie

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  13. Araya, Juan J.

    1. Isolation of Modulators of the Liver-Specific Organic Anion-Transporting Polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae)
      Megan Roth, Juan J. Araya, Barbara N. Timmermann and Bruno Hagenbuch
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 624-632; DOI: https://doi.org/10.1124/jpet.111.184564

B

  1. Bai, Jing

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  2. Bartlett, Paula J.

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  3. Bernstein, Peter R.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  4. Berwick, Zachary C.

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  5. Bess, Kirsty

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  6. Bian, Jin-Song

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  7. Boado, Ruben J.

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876

  8. Bockus, Abigail

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  9. Brockel, Becky J.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  10. Brown, Amy

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  11. Brown, Trisha A.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

  12. Bungay, Peter

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  13. Büttelmann, Bernd

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

C

  1. Cao, Jianjing

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  2. Cervantes-Gomez, Fabiola

    1. ATP Analog Enhances the Actions of a Heat Shock Protein 90 Inhibitor in Multiple Myeloma Cells
      Fabiola Cervantes-Gomez, Ramadevi Nimmanapalli and Varsha Gandhi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 545-554; DOI: https://doi.org/10.1124/jpet.111.184903

  3. Chakrabarti, Subhadeep

    1. Role of Neuronal Nitric-Oxide Synthase in Estrogen-Induced Relaxation in Rat Resistance Arteries
      Olga Lekontseva, Subhadeep Chakrabarti, Yanyan Jiang, Christopher C. Cheung and Sandra T. Davidge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 367-375; DOI: https://doi.org/10.1124/jpet.111.183798

  4. Chakraborty, Saikat

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  5. Chang, Thomas K. H.

    1. Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
      Aik Jiang Lau, Guixiang Yang and Thomas K. H. Chang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 704-715; DOI: https://doi.org/10.1124/jpet.111.186130

  6. Chang, Young-Tae

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  7. Chaudhary, Inder

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  8. Chen, Chen

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  9. Chen, Jing

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  10. Cheung, Christopher C.

    1. Role of Neuronal Nitric-Oxide Synthase in Estrogen-Induced Relaxation in Rat Resistance Arteries
      Olga Lekontseva, Subhadeep Chakrabarti, Yanyan Jiang, Christopher C. Cheung and Sandra T. Davidge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 367-375; DOI: https://doi.org/10.1124/jpet.111.183798

  11. Chi, Yuling

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  12. Christman, John W.

    1. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2
      Rui Yu, Lei Xiao, Guiqing Zhao, John W. Christman and Richard B. van Breemen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 716-725; DOI: https://doi.org/10.1124/jpet.111.185405

  13. Chu, Pei Wen

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  14. Chudnovskaya, Darina

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  15. Conrad, Kevin M.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  16. Copple, Bryan L.

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  17. Cowan, Alan

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  18. Cui, Zhiyi

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

  19. Czoty, Paul W.

    1. Effects of Varenicline on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rhesus Monkeys
      Robert W. Gould, Paul W. Czoty, Susan H. Nader and Michael A. Nader
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 678-686; DOI: https://doi.org/10.1124/jpet.111.185538

D

  1. Davidge, Sandra T.

    1. Role of Neuronal Nitric-Oxide Synthase in Estrogen-Induced Relaxation in Rat Resistance Arteries
      Olga Lekontseva, Subhadeep Chakrabarti, Yanyan Jiang, Christopher C. Cheung and Sandra T. Davidge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 367-375; DOI: https://doi.org/10.1124/jpet.111.183798

  2. Dayton, Alex

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  3. Deng, Xiaoming

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  4. De Vry, Jean

    1. Antinociceptive and Antihyperalgesic Effects of Tapentadol in Animal Models of Inflammatory Pain
      Klaus Schiene, Jean De Vry and Thomas M. Tzschentke
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 537-544; DOI: https://doi.org/10.1124/jpet.111.181263

  5. Diener, Catherine

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  6. Ding, Wen-Xing

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  7. Dong, Yi-Fei

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  8. Duan, Haichuan

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

E

  1. Edin, Matthew L.

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  2. Ellis, Jonathan D.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  3. Engel, Eli

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

F

  1. Fang, Hailin

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

  2. Feuerstein, Giora Z.

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  3. Fischer, Christophe

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  4. Flament, Christophe

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  5. Fleckenstein, Annette E.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  6. Fox, Jonathan C.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

  7. Freeman, J.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  8. Fu, Jiaqi

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

G

  1. Gandhi, Varsha

    1. ATP Analog Enhances the Actions of a Heat Shock Protein 90 Inhibitor in Multiple Myeloma Cells
      Fabiola Cervantes-Gomez, Ramadevi Nimmanapalli and Varsha Gandhi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 545-554; DOI: https://doi.org/10.1124/jpet.111.184903

  2. Gao, Ai-mei

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  3. Garber, Ellen

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  4. Gatti, Silvia

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  5. German, Christopher L.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  6. Gibb, James W.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  7. Gibson, Karl R.

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  8. Gong, Wei

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  9. Gould, Robert W.

    1. Effects of Varenicline on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rhesus Monkeys
      Robert W. Gould, Paul W. Czoty, Susan H. Nader and Michael A. Nader
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 678-686; DOI: https://doi.org/10.1124/jpet.111.185538

  10. Graff, Christilyn

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  11. Grimwood, S.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  12. Guth, Paul H.

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

H

  1. Hadlock, Gregory C.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  2. Hagenbuch, Bruno

    1. Isolation of Modulators of the Liver-Specific Organic Anion-Transporting Polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae)
      Megan Roth, Juan J. Araya, Barbara N. Timmermann and Bruno Hagenbuch
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 624-632; DOI: https://doi.org/10.1124/jpet.111.184564

  3. Hanson, Glen R.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  4. Harding, Joseph W.

    1. Mimics of the Dimerization Domain of Hepatocyte Growth Factor Exhibit Anti-Met and Anticancer Activity
      Leen H. Kawas, Brent J. Yamamoto, John W. Wright and Joseph W. Harding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 509-518; DOI: https://doi.org/10.1124/jpet.111.185694

  5. Hartung, Thomas

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  6. Hawcock, Tony

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  7. He, Lijun

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  8. Hegde, Venkatesh L.

    1. Perinatal Exposure to Δ9-Tetrahydrocannabinol Triggers Profound Defects in T Cell Differentiation and Function in Fetal and Postnatal Stages of Life, Including Decreased Responsiveness to HIV Antigens
      Catherine Lombard, Venkatesh L. Hegde, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 607-617; DOI: https://doi.org/10.1124/jpet.111.181206

  9. Hideg, Kálmán

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  10. Higashiyama, Masaaki

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

  11. Hiranita, Takato

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  12. Ho, Horace T. B.

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

  13. Hoffmann, Gerhard

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  14. Honer, Michael

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  15. Hoonakker, Amanda J.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  16. Howe, David C.

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  17. Hu, Li-Fang

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  18. Hu, Yinghui

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  19. Huang, Peng

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  20. Hui, Eric Ka-Wai

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876

I

  1. Inatomi, Nobuhiro

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  2. Inoue, Takuya

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

J

  1. Jaeschke, Georg

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  2. Jasmin, Jean-Francois

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  3. Ji, Benxiu

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  4. Jiang, Faming

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  5. Jiang, Yanyan

    1. Role of Neuronal Nitric-Oxide Synthase in Estrogen-Induced Relaxation in Rat Resistance Arteries
      Olga Lekontseva, Subhadeep Chakrabarti, Yanyan Jiang, Christopher C. Cheung and Sandra T. Davidge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 367-375; DOI: https://doi.org/10.1124/jpet.111.183798

  6. Jones, Gareth

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  7. Joshi, Chintamani N.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

K

  1. Kálai, Tamás

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  2. Kamiie, Junichi

    1. Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice
      Yasuo Uchida, Sumio Ohtsuki, Junichi Kamiie and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 579-588; DOI: https://doi.org/10.1124/jpet.111.184200

  3. Karamyan, Vardan T.

    1. Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
      Li Yang, Kaushik Shah, Hezhen Wang, Vardan T. Karamyan and Thomas J. Abbruscato
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 499-508; DOI: https://doi.org/10.1124/jpet.111.184127

  4. Kassel, Karen M.

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  5. Kataoka, Keiichiro

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  6. Katz, Jonathan L.

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  7. Kaunitz, Jonathan D.

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

  8. Kawas, Leen H.

    1. Mimics of the Dimerization Domain of Hepatocyte Growth Factor Exhibit Anti-Met and Anticancer Activity
      Leen H. Kawas, Brent J. Yamamoto, John W. Wright and Joseph W. Harding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 509-518; DOI: https://doi.org/10.1124/jpet.111.185694

  9. Khan, Mahmood

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  10. Khomenko, Tetyana

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  11. Khroyan, Taline V.

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  12. Kim-Mitsuyama, Shokei

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  13. Kocarek, Thomas A.

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

  14. Kohut, Stephen J.

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  15. Koibuchi, Nobutaka

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  16. Kolczewski, Sabine

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  17. Kopajtic, Theresa

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  18. Kumar, Sanjay

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  19. Kuppusamy, M. Lakshmi

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  20. Kuppusamy, Periannan

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

L

  1. Lambert, Nevin A.

    1. Effects of Chlorpyrifos and Chlorpyrifos-Oxon on the Dynamics and Movement of Mitochondria in Rat Cortical Neurons
      Mary-Louise Middlemore-Risher, Bao-Ling Adam, Nevin A. Lambert and Alvin V. Terry
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 341-349; DOI: https://doi.org/10.1124/jpet.111.184762

  2. Lau, Aik Jiang

    1. Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
      Aik Jiang Lau, Guixiang Yang and Thomas K. H. Chang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 704-715; DOI: https://doi.org/10.1124/jpet.111.186130

  3. Lee, Shiau Wei

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  4. Lee, Xinhua

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  5. Lekontseva, Olga

    1. Role of Neuronal Nitric-Oxide Synthase in Estrogen-Induced Relaxation in Rat Resistance Arteries
      Olga Lekontseva, Subhadeep Chakrabarti, Yanyan Jiang, Christopher C. Cheung and Sandra T. Davidge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 367-375; DOI: https://doi.org/10.1124/jpet.111.183798

  6. Li, Rui-wen

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  7. Li, Xiao-hai

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  8. Li, Yu

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  9. Li, Yuanjing

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  10. Lindemann, Lothar

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  11. Lisanti, Michael P.

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  12. Liu, Eddie C.-K.

    1. Dissecting the Activation of Thienopyridines by Cytochromes P450 Using a Pharmacodynamic Assay In Vitro
      Lynn M. Abell and Eddie C.-K. Liu
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 589-596; DOI: https://doi.org/10.1124/jpet.111.184895

  13. Liu, Lian

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  14. Liu, Liu

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  15. Liu, Mingyao

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  16. Liu-Chen, Lee-Yuan

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  17. Ljungman, Mats

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

  18. Lombard, Catherine

    1. Perinatal Exposure to Δ9-Tetrahydrocannabinol Triggers Profound Defects in T Cell Differentiation and Function in Fetal and Postnatal Stages of Life, Including Decreased Responsiveness to HIV Antigens
      Catherine Lombard, Venkatesh L. Hegde, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 607-617; DOI: https://doi.org/10.1124/jpet.111.181206

  19. Lu, Jeff Zhiqiang

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876

  20. Lu, Y.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  21. Luyendyk, James P.

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

M

  1. Maier, Donna L.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  2. Manley, Sharon

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  3. Martin, Danielle N.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

  4. McFadden, Lisa M.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  5. McLaughlin, J. P.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  6. McLean, S.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  7. McLeod, Alison

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  8. Meduru, Sarath

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  9. Mei, Shuang

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  10. Meier, Werner

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  11. Mendelev, Natalia N.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

  12. Meng, Gym

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  13. Mi, Sha

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  14. Michalon, Aubin

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  15. Middlemore-Risher, Mary-Louise

    1. Effects of Chlorpyrifos and Chlorpyrifos-Oxon on the Dynamics and Movement of Mitochondria in Rat Cortical Neurons
      Mary-Louise Middlemore-Risher, Bao-Ling Adam, Nevin A. Lambert and Alvin V. Terry
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 341-349; DOI: https://doi.org/10.1124/jpet.111.184762

  16. Miller, E.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  17. Min, Jaeki

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  18. Montenegro, Jose

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  19. Moraga-Cid, Gustavo

    1. Activated G Protein αs Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors
      Gonzalo E. Yévenes, Gustavo Moraga-Cid, Ximena Romo and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 386-393; DOI: https://doi.org/10.1124/jpet.111.184408

  20. Mount, Natalie M.

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  21. Munson, Keith

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  22. Murayama, Norie

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009

N

  1. Nader, Michael A.

    1. Effects of Varenicline on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rhesus Monkeys
      Robert W. Gould, Paul W. Czoty, Susan H. Nader and Michael A. Nader
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 678-686; DOI: https://doi.org/10.1124/jpet.111.185538

  2. Nader, Susan H.

    1. Effects of Varenicline on the Reinforcing and Discriminative Stimulus Effects of Cocaine in Rhesus Monkeys
      Robert W. Gould, Paul W. Czoty, Susan H. Nader and Michael A. Nader
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 678-686; DOI: https://doi.org/10.1124/jpet.111.185538

  3. Nagarkatti, Mitzi

    1. Perinatal Exposure to Δ9-Tetrahydrocannabinol Triggers Profound Defects in T Cell Differentiation and Function in Fetal and Postnatal Stages of Life, Including Decreased Responsiveness to HIV Antigens
      Catherine Lombard, Venkatesh L. Hegde, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 607-617; DOI: https://doi.org/10.1124/jpet.111.181206

  4. Nagarkatti, Prakash S.

    1. Perinatal Exposure to Δ9-Tetrahydrocannabinol Triggers Profound Defects in T Cell Differentiation and Function in Fetal and Postnatal Stages of Life, Including Decreased Responsiveness to HIV Antigens
      Catherine Lombard, Venkatesh L. Hegde, Mitzi Nagarkatti and Prakash S. Nagarkatti
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 607-617; DOI: https://doi.org/10.1124/jpet.111.181206

  5. Naidu, Shan

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  6. Nakamura, Taishi

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  7. Nakanishi, Yasuharu

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009

  8. Nako, Hisato

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  9. Neo, Kay Li

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  10. Newman, Amy H.

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  11. Ni, Hong-Min

    1. Differential Roles of Unsaturated and Saturated Fatty Acids on Autophagy and Apoptosis in Hepatocytes
      Shuang Mei, Hong-Min Ni, Sharon Manley, Abigail Bockus, Karen M. Kassel, James P. Luyendyk, Bryan L. Copple and Wen-Xing Ding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 487-498; DOI: https://doi.org/10.1124/jpet.111.184341

  12. Nimmanapalli, Ramadevi

    1. ATP Analog Enhances the Actions of a Heat Shock Protein 90 Inhibitor in Multiple Myeloma Cells
      Fabiola Cervantes-Gomez, Ramadevi Nimmanapalli and Varsha Gandhi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 545-554; DOI: https://doi.org/10.1124/jpet.111.184903

O

  1. Obukhov, Alexander G.

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  2. Ogawa, Hisao

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  3. Ohtsuki, Sumio

    1. Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice
      Yasuo Uchida, Sumio Ohtsuki, Junichi Kamiie and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 579-588; DOI: https://doi.org/10.1124/jpet.111.184200

  4. Orduna, Juan

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

P

  1. Pan, Yongmei

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

  2. Pang, Xiufeng

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  3. Pardridge, William M.

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876

  4. Parrott, Neil

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  5. Paulsen, Michelle

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

  6. Paunovic, Brankica

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  7. Pepinsky, R. Blake

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  8. Pierson, M. Edward

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  9. Ping, Jie

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  10. Polgar, Willma E.

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  11. Porter, Richard

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  12. Potts, William M.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  13. Prinssen, Eric P.

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  14. Pullen, Nick

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

Q

  1. Qin, Hai-quan

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

R

  1. Ramsey, Simeon

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  2. Rasakham, Khampaseuth

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  3. Reidenberg, Marcus M.

    1. Drug Discontinuation Effects Are Part of the Pharmacology of a Drug
      Marcus M. Reidenberg
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 324-328; DOI: https://doi.org/10.1124/jpet.111.183285

  4. Richard, Jacques

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  5. Romo, Ximena

    1. Activated G Protein αs Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors
      Gonzalo E. Yévenes, Gustavo Moraga-Cid, Ximena Romo and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 386-393; DOI: https://doi.org/10.1124/jpet.111.184408

  6. Roth, Megan

    1. Isolation of Modulators of the Liver-Specific Organic Anion-Transporting Polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae)
      Megan Roth, Juan J. Araya, Barbara N. Timmermann and Bruno Hagenbuch
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 624-632; DOI: https://doi.org/10.1124/jpet.111.184564

  7. Runge-Morris, Melissa

    1. Regulation of Estrogen Sulfotransferase Expression by Confluence of MCF10A Breast Epithelial Cells: Role of the Aryl Hydrocarbon Receptor
      Jiaqi Fu, Hailin Fang, Michelle Paulsen, Mats Ljungman, Thomas A. Kocarek and Melissa Runge-Morris
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 597-606; DOI: https://doi.org/10.1124/jpet.111.185173

S

  1. Sachs, George

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  2. Sandor, Zsuzsanna

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  3. Sawant-Basak, A.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  4. Schiene, Klaus

    1. Antinociceptive and Antihyperalgesic Effects of Tapentadol in Animal Models of Inflammatory Pain
      Klaus Schiene, Jean De Vry and Thomas M. Tzschentke
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 537-544; DOI: https://doi.org/10.1124/jpet.111.181263

  5. Schmidt, A. W.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  6. Schuster, Victor L.

    1. Development of a High-Affinity Inhibitor of the Prostaglandin Transporter
      Yuling Chi, Jaeki Min, Jean-Francois Jasmin, Michael P. Lisanti, Young-Tae Chang and Victor L. Schuster
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 633-641; DOI: https://doi.org/10.1124/jpet.111.181354

  7. Selvendiran, Karuppaiyah

    1. Amelioration of Doxorubicin-Induced Cardiotoxicity by an Anticancer-Antioxidant Dual-Function Compound, HO-3867
      Alex Dayton, Karuppaiyah Selvendiran, Sarath Meduru, Mahmood Khan, M. Lakshmi Kuppusamy, Shan Naidu, Tamás Kálai, Kálmán Hideg and Periannan Kuppusamy
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 350-357; DOI: https://doi.org/10.1124/jpet.111.183681

  8. Shah, Kaushik

    1. Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
      Li Yang, Kaushik Shah, Hezhen Wang, Vardan T. Karamyan and Thomas J. Abbruscato
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 499-508; DOI: https://doi.org/10.1124/jpet.111.184127

  9. Shao, Zhaohui

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  10. Shenvi, Ashok B.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  11. Shin, Jai Moo

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  12. Sobotka-Briner, Cynthia D.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  13. Soto, Paul L.

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  14. Spooren, Will

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  15. Strugatsky, David

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  16. Sturek, Michael

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  17. Sueta, Daisuke

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  18. Sumbria, Rachita

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876

  19. Swaan, Peter W.

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

  20. Szabo, Sandor

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

T

  1. Tan, Benny Kwong Huat

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  2. Tanda, Gianluigi

    1. Decreases in Cocaine Self-Administration with Dual Inhibition of the Dopamine Transporter and σ Receptors
      Takato Hiranita, Paul L. Soto, Stephen J. Kohut, Theresa Kopajtic, Jianjing Cao, Amy H. Newman, Gianluigi Tanda and Jonathan L. Katz
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 662-677; DOI: https://doi.org/10.1124/jpet.111.185025

  3. Tarnawski, Andrzej

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  4. Terasaki, Tetsuya

    1. Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice
      Yasuo Uchida, Sumio Ohtsuki, Junichi Kamiie and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 579-588; DOI: https://doi.org/10.1124/jpet.111.184200

  5. Terry, Alvin V.

    1. Effects of Chlorpyrifos and Chlorpyrifos-Oxon on the Dynamics and Movement of Mitochondria in Rat Cortical Neurons
      Mary-Louise Middlemore-Risher, Bao-Ling Adam, Nevin A. Lambert and Alvin V. Terry
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 341-349; DOI: https://doi.org/10.1124/jpet.111.184762

  6. Thomas, Andrew P.

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  7. Timmermann, Barbara N.

    1. Isolation of Modulators of the Liver-Specific Organic Anion-Transporting Polypeptides (OATPs) 1B1 and 1B3 from Rollinia emarginata Schlecht (Annonaceae)
      Megan Roth, Juan J. Araya, Barbara N. Timmermann and Bruno Hagenbuch
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 624-632; DOI: https://doi.org/10.1124/jpet.111.184564

  8. Tokhtaeva, Elmira

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  9. Tokutomi, Yoshiko

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  10. Toll, Lawrence

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  11. Tolstanova, Ganna

    1. Molecular Mechanisms of Basic Fibroblast Growth Factor Effect on Healing of Ulcerative Colitis in Rats
      Brankica Paunovic, Xiaoming Deng, Tetyana Khomenko, Amrita Ahluwalia, Ganna Tolstanova, Andrzej Tarnawski, Sandor Szabo and Zsuzsanna Sandor
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 430-437; DOI: https://doi.org/10.1124/jpet.111.183665

  12. Toyama, Kensuke

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  13. Tulis, David A.

    1. The Soluble Guanylate Cyclase Stimulator BAY 41-2272 Inhibits Vascular Smooth Muscle Growth through the cAMP-Dependent Protein Kinase and cGMP-Dependent Protein Kinase Pathways
      Chintamani N. Joshi, Danielle N. Martin, Jonathan C. Fox, Natalia N. Mendelev, Trisha A. Brown and David A. Tulis
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 394-402; DOI: https://doi.org/10.1124/jpet.111.183400

  14. Tune, Johnathan D.

    1. Bromoenol Lactone Inhibits Voltage-Gated Ca2+ and Transient Receptor Potential Canonical Channels
      Saikat Chakraborty, Zachary C. Berwick, Paula J. Bartlett, Sanjay Kumar, Andrew P. Thomas, Michael Sturek, Johnathan D. Tune and Alexander G. Obukhov
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 329-340; DOI: https://doi.org/10.1124/jpet.111.183673

  15. Tweedy, Sarah

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  16. Tzschentke, Thomas M.

    1. Antinociceptive and Antihyperalgesic Effects of Tapentadol in Animal Models of Inflammatory Pain
      Klaus Schiene, Jean De Vry and Thomas M. Tzschentke
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 537-544; DOI: https://doi.org/10.1124/jpet.111.181263

U

  1. Uchida, Yasuo

    1. Blood-Brain Barrier (BBB) Pharmacoproteomics: Reconstruction of In Vivo Brain Distribution of 11 P-Glycoprotein Substrates Based on the BBB Transporter Protein Concentration, In Vitro Intrinsic Transport Activity, and Unbound Fraction in Plasma and Brain in Mice
      Yasuo Uchida, Sumio Ohtsuki, Junichi Kamiie and Tetsuya Terasaki
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 579-588; DOI: https://doi.org/10.1124/jpet.111.184200

  2. Uehara, Shotaro

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009

  3. Uno, Yasuhiro

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009

V

  1. Vagin, Olga

    1. Characterization of a Novel Potassium-Competitive Acid Blocker of the Gastric H,K-ATPase, 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438)
      Jai Moo Shin, Nobuhiro Inatomi, Keith Munson, David Strugatsky, Elmira Tokhtaeva, Olga Vagin and George Sachs
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 412-420; DOI: https://doi.org/10.1124/jpet.111.185314

  2. Vanase-Frawley, M. A.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  3. van Breemen, Richard B.

    1. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2
      Rui Yu, Lei Xiao, Guiqing Zhao, John W. Christman and Richard B. van Breemen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 716-725; DOI: https://doi.org/10.1124/jpet.111.185405

  4. Verhoest, P. R.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  5. Vieira, Eric

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  6. Vieira-Brock, Paula L.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

W

  1. Walley, Rosalind

    1. The Translational Efficacy of a Nonsteroidal Progesterone Receptor Antagonist, 4-[3-Cyclopropyl-1-(mesylmethyl)-5-methyl-1H-pyrazol-4-yl]oxy,-2,6-dimethylbenzonitrile (PF-02413873), on Endometrial Growth in Macaque and Human
      David C. Howe, Natalie M. Mount, Kirsty Bess, Amy Brown, Peter Bungay, Karl R. Gibson, Tony Hawcock, Jacques Richard, Gareth Jones, Rosalind Walley, Alison McLeod, Coralie Apfeldorfer, Simeon Ramsey, Sarah Tweedy and Nick Pullen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 642-653; DOI: https://doi.org/10.1124/jpet.111.183848

  2. Walus, Lee

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  3. Wang, Dao Wen

    1. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  4. Wang, Hezhen

    1. Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
      Li Yang, Kaushik Shah, Hezhen Wang, Vardan T. Karamyan and Thomas J. Abbruscato
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 499-508; DOI: https://doi.org/10.1124/jpet.111.184127

  5. Wang, Hui

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  6. Wang, Joanne

    1. Molecular Analysis and Structure-Activity Relationship Modeling of the Substrate/Inhibitor Interaction Site of Plasma Membrane Monoamine Transporter
      Horace T. B. Ho, Yongmei Pan, Zhiyi Cui, Haichuan Duan, Peter W. Swaan and Joanne Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 376-385; DOI: https://doi.org/10.1124/jpet.111.184036

  7. Wang, Joon-Ho

    1. Umami Receptor Activation Increases Duodenal Bicarbonate Secretion via Glucagon-Like Peptide-2 Release in Rats
      Joon-Ho Wang, Takuya Inoue, Masaaki Higashiyama, Paul H. Guth, Eli Engel, Jonathan D. Kaunitz and Yasutada Akiba
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 464-473; DOI: https://doi.org/10.1124/jpet.111.184788

  8. Wang, Qin

    1. Exposure Levels of Anti-LINGO-1 Li81 Antibody in the Central Nervous System and Dose-Efficacy Relationships in Rat Spinal Cord Remyelination Models after Systemic Administration
      R. Blake Pepinsky, Zhaohui Shao, Benxiu Ji, Qin Wang, Gym Meng, Lee Walus, Xinhua Lee, Yinghui Hu, Christilyn Graff, Ellen Garber, Werner Meier and Sha Mi
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 519-529; DOI: https://doi.org/10.1124/jpet.111.183483

  9. Wang, Xinkang

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  10. Wang, Yi

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  11. Wang, Yu-Jun

    1. Sex Difference in κ-Opioid Receptor (KOPR)-Mediated Behaviors, Brain Region KOPR Level and KOPR-Mediated Guanosine 5′-O-(3-[35S]Thiotriphosphate) Binding in the Guinea Pig
      Yu-Jun Wang, Khampaseuth Rasakham, Peng Huang, Darina Chudnovskaya, Alan Cowan and Lee-Yuan Liu-Chen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 438-450; DOI: https://doi.org/10.1124/jpet.111.183905

  12. Webb, Katy M.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  13. Wei, Xiao-ning

    1. RETRACTION: Indole-3-Carbinol Enhances the Resolution of Rat Liver Fibrosis and Stimulates Hepatic Stellate Cell Apoptosis by Blocking the Inhibitor of κB Kinase α/Inhibitor of κB-α/Nuclear Factor-κB Pathway
      Jie Ping, Ai-mei Gao, Hai-quan Qin, Xiao-ning Wei, Jing Bai, Lian Liu, Xiao-hai Li, Rui-wen Li, Ying Ao and Hui Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 694-703; DOI: https://doi.org/10.1124/jpet.111.179820

  14. Wettstein, Joseph G.

    1. CTEP: A Novel, Potent, Long-Acting, and Orally Bioavailable Metabotropic Glutamate Receptor 5 Inhibitor
      Lothar Lindemann, Georg Jaeschke, Aubin Michalon, Eric Vieira, Michael Honer, Will Spooren, Richard Porter, Thomas Hartung, Sabine Kolczewski, Bernd Büttelmann, Christophe Flament, Catherine Diener, Christophe Fischer, Silvia Gatti, Eric P. Prinssen, Neil Parrott, Gerhard Hoffmann and Joseph G. Wettstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 474-486; DOI: https://doi.org/10.1124/jpet.111.185660

  15. Widzowski, Daniel V.

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  16. Wilkins, Diana G.

    1. 4-Methylmethcathinone (Mephedrone): Neuropharmacological Effects of a Designer Stimulant of Abuse
      Gregory C. Hadlock, Katy M. Webb, Lisa M. McFadden, Pei Wen Chu, Jonathan D. Ellis, Scott C. Allen, David M. Andrenyak, Paula L. Vieira-Brock, Christopher L. German, Kevin M. Conrad, Amanda J. Hoonakker, James W. Gibb, Diana G. Wilkins, Glen R. Hanson and Annette E. Fleckenstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 530-536; DOI: https://doi.org/10.1124/jpet.111.184119

  17. Wong, S.

    1. Pharmacological Characterization of 2-Methyl-N-((2′-(pyrrolidin-1-ylsulfonyl)biphenyl-4-yl)methyl)propan-1-amine (PF-04455242), a High-Affinity Antagonist Selective for κ-Opioid Receptors
      S. Grimwood, Y. Lu, A. W. Schmidt, M. A. Vanase-Frawley, A. Sawant-Basak, E. Miller, S. McLean, J. Freeman, S. Wong, J. P. McLaughlin and P. R. Verhoest
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 555-566; DOI: https://doi.org/10.1124/jpet.111.185108

  18. Wright, John W.

    1. Mimics of the Dimerization Domain of Hepatocyte Growth Factor Exhibit Anti-Met and Anticancer Activity
      Leen H. Kawas, Brent J. Yamamoto, John W. Wright and Joseph W. Harding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 509-518; DOI: https://doi.org/10.1124/jpet.111.185694

  19. Wu, Yuanyuan

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

X

  1. Xiao, Lei

    1. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2
      Rui Yu, Lei Xiao, Guiqing Zhao, John W. Christman and Richard B. van Breemen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 716-725; DOI: https://doi.org/10.1124/jpet.111.185405

Y

  1. Yamamoto, Brent J.

    1. Mimics of the Dimerization Domain of Hepatocyte Growth Factor Exhibit Anti-Met and Anticancer Activity
      Leen H. Kawas, Brent J. Yamamoto, John W. Wright and Joseph W. Harding
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 509-518; DOI: https://doi.org/10.1124/jpet.111.185694

  2. Yamamoto, Eiichiro

    1. Beneficial Effects of Combination of Valsartan and Amlodipine on Salt-Induced Brain Injury in Hypertensive Rats
      Yi-Fei Dong, Keiichiro Kataoka, Yoshiko Tokutomi, Hisato Nako, Taishi Nakamura, Kensuke Toyama, Daisuke Sueta, Nobutaka Koibuchi, Eiichiro Yamamoto, Hisao Ogawa and Shokei Kim-Mitsuyama
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 358-366; DOI: https://doi.org/10.1124/jpet.111.182576

  3. Yamazaki, Hiroshi

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009

  4. Yang, Guixiang

    1. Isoform-Selective Activation of Human Constitutive Androstane Receptor by Ginkgo biloba Extract: Functional Analysis of the SV23, SV24, and SV25 Splice Variants
      Aik Jiang Lau, Guixiang Yang and Thomas K. H. Chang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 704-715; DOI: https://doi.org/10.1124/jpet.111.186130

  5. Yang, Li

    1. Characterization of Neuroprotective Effects of Biphalin, an Opioid Receptor Agonist, in a Model of Focal Brain Ischemia
      Li Yang, Kaushik Shah, Hezhen Wang, Vardan T. Karamyan and Thomas J. Abbruscato
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 499-508; DOI: https://doi.org/10.1124/jpet.111.184127

  6. Yévenes, Gonzalo E.

    1. Activated G Protein αs Subunits Increase the Ethanol Sensitivity of Human Glycine Receptors
      Gonzalo E. Yévenes, Gustavo Moraga-Cid, Ximena Romo and Luis G. Aguayo
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 386-393; DOI: https://doi.org/10.1124/jpet.111.184408

  7. Yi, Zhengfang

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  8. Yong, Qian Chen

    1. Hydrogen Sulfide Regulates Na+/H+ Exchanger Activity via Stimulation of Phosphoinositide 3-Kinase/Akt and Protein Kinase G Pathways
      Li-Fang Hu, Yu Li, Kay Li Neo, Qian Chen Yong, Shiau Wei Lee, Benny Kwong Huat Tan and Jin-Song Bian
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 726-735; DOI: https://doi.org/10.1124/jpet.111.184754

  9. Yu, Rui

    1. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2
      Rui Yu, Lei Xiao, Guiqing Zhao, John W. Christman and Richard B. van Breemen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 716-725; DOI: https://doi.org/10.1124/jpet.111.185405

Z

  1. Zaveri, Nurulain T.

    1. Differential Effects of Nociceptin/Orphanin FQ (NOP) Receptor Agonists in Acute versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
      Taline V. Khroyan, Willma E. Polgar, Juan Orduna, Jose Montenegro, Faming Jiang, Nurulain T. Zaveri and Lawrence Toll
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 687-693; DOI: https://doi.org/10.1124/jpet.111.184663

  2. Zeldin, Darryl C.

    1. Immunochemical Detection of Cytochrome P450 Enzymes in Liver Microsomes of 27 Cynomolgus Monkeys
      Shotaro Uehara, Norie Murayama, Yasuharu Nakanishi, Darryl C. Zeldin, Hiroshi Yamazaki and Yasuhiro Uno
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 654-661; DOI: https://doi.org/10.1124/jpet.111.185009
    2. Epoxyeicosatrienoic Acids Attenuate Reactive Oxygen Species Level, Mitochondrial Dysfunction, Caspase Activation, and Apoptosis in Carcinoma Cells Treated with Arsenic Trioxide
      Liu Liu, Chen Chen, Wei Gong, Yuanjing Li, Matthew L. Edin, Darryl C. Zeldin and Dao Wen Wang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 451-463; DOI: https://doi.org/10.1124/jpet.111.180505

  3. Zhan, Yutian

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  4. Zhang, Jian

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  5. Zhang, Li

    1. Anacardic Acid (6-Pentadecylsalicylic Acid) Inhibits Tumor Angiogenesis by Targeting Src/FAK/Rho GTPases Signaling Pathway
      Yuanyuan Wu, Lijun He, Li Zhang, Jing Chen, Zhengfang Yi, Jian Zhang, Mingyao Liu and Xiufeng Pang
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 403-411; DOI: https://doi.org/10.1124/jpet.111.181891

  6. Zhang, Minli

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  7. Zhao, Guiqing

    1. Competitive Enzymatic Interactions Determine the Relative Amounts of Prostaglandins E2 and D2
      Rui Yu, Lei Xiao, Guiqing Zhao, John W. Christman and Richard B. van Breemen
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 716-725; DOI: https://doi.org/10.1124/jpet.111.185405

  8. Zhao, Lei

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  9. Zhou, Bin-Bing

    1. Multimodal Biomarker Investigation on Efficacy and Mechanism of Action for the Mammalian Target of Rapamycin Inhibitor, Temsirolimus, in a Preclinical Mammary Carcinoma OncoMouse Model: A Translational Medicine Study in Support for Early Clinical Development
      Xinkang Wang, Yutian Zhan, Lei Zhao, John Alvarez, Inder Chaudhary, Bin-Bing Zhou, Robert T. Abraham and Giora Z. Feuerstein
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 421-429; DOI: https://doi.org/10.1124/jpet.111.185249

  10. Zhou, Diansong

    1. Preclinical Pharmacology and Pharmacokinetics of AZD3783, a Selective 5-Hydroxytryptamine 1B Receptor Antagonist
      Minli Zhang, Diansong Zhou, Yi Wang, Donna L. Maier, Daniel V. Widzowski, Cynthia D. Sobotka-Briner, Becky J. Brockel, William M. Potts, Ashok B. Shenvi, Peter R. Bernstein and M. Edward Pierson
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 567-578; DOI: https://doi.org/10.1124/jpet.110.174433

  11. Zhou, Qing-Hui

    1. Neuroprotection with a Brain-Penetrating Biologic Tumor Necrosis Factor Inhibitor
      Qing-Hui Zhou, Rachita Sumbria, Eric Ka-Wai Hui, Jeff Zhiqiang Lu, Ruben J. Boado and William M. Pardridge
      Journal of Pharmacology and Experimental Therapeutics November 2011, 339 (2) 618-623; DOI: https://doi.org/10.1124/jpet.111.185876
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