Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

Niu Shin; Kim Solomon; Naiming Zhou; Kathy He Wang; Vasudha Garlapati; Beth Thomas; Yanlong Li; Maryanne Covington; Frederic Baribaud; Susan Erickson-Viitanen; Phil Czerniak; Nancy Contel; Phillip Liu; Timothy Burn; Gregory Hollis; Swamy Yeleswaram; Kris Vaddi; Chu-Biao Xue; Brian Metcalf; Steve Friedman; Peggy Scherle; Robert Newton

doi:10.1124/jpet.111.179531

Research ArticleCellular and Molecular

Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

Niu Shin, Kim Solomon, Naiming Zhou, Kathy He Wang, Vasudha Garlapati, Beth Thomas, Yanlong Li, Maryanne Covington, Frederic Baribaud, Susan Erickson-Viitanen, Phil Czerniak, Nancy Contel, Phillip Liu, Timothy Burn, Gregory Hollis, Swamy Yeleswaram, Kris Vaddi, Chu-Biao Xue, Brian Metcalf, Steve Friedman, Peggy Scherle and Robert Newton

Journal of Pharmacology and Experimental Therapeutics July 2011, 338 (1) 228-239; DOI: https://doi.org/10.1124/jpet.111.179531

Niu Shin

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Kim Solomon

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Naiming Zhou

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Kathy He Wang

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Vasudha Garlapati

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Beth Thomas

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Yanlong Li

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Maryanne Covington

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Frederic Baribaud

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Susan Erickson-Viitanen

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Phil Czerniak

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Nancy Contel

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Phillip Liu

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Timothy Burn

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Gregory Hollis

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Swamy Yeleswaram

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Kris Vaddi

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Chu-Biao Xue

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Brian Metcalf

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Steve Friedman

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Peggy Scherle

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Robert Newton

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Journal of Pharmacology and Experimental Therapeutics

Vol. 338, Issue 1

1 Jul 2011

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Research ArticleCellular and Molecular

Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

Journal of Pharmacology and Experimental Therapeutics July 1, 2011, 338 (1) 228-239; DOI: https://doi.org/10.1124/jpet.111.179531

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Research ArticleCellular and Molecular

Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

Journal of Pharmacology and Experimental Therapeutics July 1, 2011, 338 (1) 228-239; DOI: https://doi.org/10.1124/jpet.111.179531

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Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

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Identification and Characterization of INCB9471, an Allosteric Noncompetitive Small-Molecule Antagonist of C-C Chemokine Receptor 5 with Potent Inhibitory Activity against Monocyte Migration and HIV-1 Infection

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