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Research ArticleMetabolism, Transport, and Pharmacogenomics

Three-Dimensional Quantitative Structure-Activity Relationship Studies on UGT1A9-Mediated 3-O-Glucuronidation of Natural Flavonols Using a Pharmacophore-Based Comparative Molecular Field Analysis Model

Baojian Wu, John Kenneth Morrow, Rashim Singh, Shuxing Zhang and Ming Hu
Journal of Pharmacology and Experimental Therapeutics February 2011, 336 (2) 403-413; DOI: https://doi.org/10.1124/jpet.110.175356
Baojian Wu
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John Kenneth Morrow
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Rashim Singh
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Shuxing Zhang
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Ming Hu
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Article Information

vol. 336 no. 2 403-413
DOI 
https://doi.org/10.1124/jpet.110.175356
PubMed 
21068207

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 23, 2010
  • Accepted November 4, 2010
  • Published online January 18, 2011.

Article Versions

  • Earlier version (November 10, 2010 - 08:25).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2011 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Baojian Wu,
  2. John Kenneth Morrow,
  3. Rashim Singh,
  4. Shuxing Zhang and
  5. Ming Hu
  1. Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (B.W., R.S., M.H.); and Department of Experimental Therapeutics, University of Texas M. D. Anderson Cancer Center, Houston, Texas (J.K.M., S.Z.)
  1. Address correspondence to:
    Dr. Ming Hu, Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, 1441 Moursund Street, Houston, TX 77030. E-mail: mhu{at}uh.edu
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Journal of Pharmacology and Experimental Therapeutics: 376 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 3
1 Mar 2021
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Research ArticleMetabolism, Transport, and Pharmacogenomics

Three-Dimensional Quantitative Structure-Activity Relationship Studies on UGT1A9-Mediated 3-O-Glucuronidation of Natural Flavonols Using a Pharmacophore-Based Comparative Molecular Field Analysis Model

Baojian Wu, John Kenneth Morrow, Rashim Singh, Shuxing Zhang and Ming Hu
Journal of Pharmacology and Experimental Therapeutics February 1, 2011, 336 (2) 403-413; DOI: https://doi.org/10.1124/jpet.110.175356

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Research ArticleMetabolism, Transport, and Pharmacogenomics

Three-Dimensional Quantitative Structure-Activity Relationship Studies on UGT1A9-Mediated 3-O-Glucuronidation of Natural Flavonols Using a Pharmacophore-Based Comparative Molecular Field Analysis Model

Baojian Wu, John Kenneth Morrow, Rashim Singh, Shuxing Zhang and Ming Hu
Journal of Pharmacology and Experimental Therapeutics February 1, 2011, 336 (2) 403-413; DOI: https://doi.org/10.1124/jpet.110.175356
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