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Research ArticleNEUROPHARMACOLOGY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

Béla Kiss, Attila Horváth, Zsolt Némethy, Éva Schmidt, István Laszlovszky, Gyula Bugovics, Károly Fazekas, Katalin Hornok, Szabolcs Orosz, István Gyertyán, Éva Ágai-Csongor, György Domány, Károly Tihanyi, Nika Adham and Zsolt Szombathelyi
Journal of Pharmacology and Experimental Therapeutics April 2010, 333 (1) 328-340; DOI: https://doi.org/10.1124/jpet.109.160432
Béla Kiss
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Attila Horváth
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Zsolt Némethy
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Éva Schmidt
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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István Laszlovszky
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Gyula Bugovics
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Károly Fazekas
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Katalin Hornok
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Szabolcs Orosz
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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István Gyertyán
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Éva Ágai-Csongor
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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György Domány
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Károly Tihanyi
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Nika Adham
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Zsolt Szombathelyi
Research and Development, Gedeon Richter Plc., Budapest, Hungary (B.K., A.H., Z.N., E.S., I.L., G.B., K.F., K.H., S.O., I.G., E.A.-C., G.D., K.T., Z.S.); and Forest Research Institute, Division of Forest Laboratories Inc., Jersey City, New Jersey (N.A.)
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Journal of Pharmacology and Experimental Therapeutics: 376 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 3
1 Mar 2021
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Research ArticleNEUROPHARMACOLOGY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

Béla Kiss, Attila Horváth, Zsolt Némethy, Éva Schmidt, István Laszlovszky, Gyula Bugovics, Károly Fazekas, Katalin Hornok, Szabolcs Orosz, István Gyertyán, Éva Ágai-Csongor, György Domány, Károly Tihanyi, Nika Adham and Zsolt Szombathelyi
Journal of Pharmacology and Experimental Therapeutics April 1, 2010, 333 (1) 328-340; DOI: https://doi.org/10.1124/jpet.109.160432

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Research ArticleNEUROPHARMACOLOGY

Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist–Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile

Béla Kiss, Attila Horváth, Zsolt Némethy, Éva Schmidt, István Laszlovszky, Gyula Bugovics, Károly Fazekas, Katalin Hornok, Szabolcs Orosz, István Gyertyán, Éva Ágai-Csongor, György Domány, Károly Tihanyi, Nika Adham and Zsolt Szombathelyi
Journal of Pharmacology and Experimental Therapeutics April 1, 2010, 333 (1) 328-340; DOI: https://doi.org/10.1124/jpet.109.160432
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