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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines, Peng Gao, Wenxue Wang, Vladimir Beljanski, John J. Upson, Cecelia L. Green, Staci N. Keller and Charles D. Smith
Journal of Pharmacology and Experimental Therapeutics April 2010, 333 (1) 129-139; DOI: https://doi.org/10.1124/jpet.109.163444
Kevin J. French
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Yan Zhuang
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Lynn W. Maines
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Peng Gao
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Wenxue Wang
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Vladimir Beljanski
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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John J. Upson
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Cecelia L. Green
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Staci N. Keller
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Charles D. Smith
Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
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Journal of Pharmacology and Experimental Therapeutics: 333 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 333, Issue 1
1 Apr 2010
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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines, Peng Gao, Wenxue Wang, Vladimir Beljanski, John J. Upson, Cecelia L. Green, Staci N. Keller and Charles D. Smith
Journal of Pharmacology and Experimental Therapeutics April 1, 2010, 333 (1) 129-139; DOI: https://doi.org/10.1124/jpet.109.163444

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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines, Peng Gao, Wenxue Wang, Vladimir Beljanski, John J. Upson, Cecelia L. Green, Staci N. Keller and Charles D. Smith
Journal of Pharmacology and Experimental Therapeutics April 1, 2010, 333 (1) 129-139; DOI: https://doi.org/10.1124/jpet.109.163444
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