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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines, Peng Gao, Wenxue Wang, Vladimir Beljanski, John J. Upson, Cecelia L. Green, Staci N. Keller and Charles D. Smith
Journal of Pharmacology and Experimental Therapeutics April 2010, 333 (1) 129-139; DOI: https://doi.org/10.1124/jpet.109.163444

Article Information

vol. 333 no. 1 129-139
DOI 
https://doi.org/10.1124/jpet.109.163444
PubMed 
20061445
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 6, 2009
  • Accepted January 7, 2010
  • Published online March 19, 2010.

Article Versions

Copyright & Usage 
Copyright © 2010 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Kevin J. French1,
  2. Yan Zhuang,
  3. Lynn W. Maines,
  4. Peng Gao,
  5. Wenxue Wang,
  6. Vladimir Beljanski,
  7. John J. Upson1,
  8. Cecelia L. Green,
  9. Staci N. Keller, and
  10. Charles D. Smith
  1. Apogee Biotechnology Corporation, Hummelstown, Pennsylvania (K.J.F., Y.Z., L.W.M., J.J.U., C.L.G., S.N.K., C.D.S.); and Department of Pharmaceutical and Biomedical Sciences, Medical University of South Carolina, Charleston, South Carolina (P.G., W.W., V.B., C.D.S.)
  1. Address correspondence to:
    Dr. Charles D. Smith, Apogee Biotechnology Corporation, 1214 Research Blvd, Suite 1016, Hummelstown, PA 17036. E-mail: cdsmith{at}apogee-biotech.com
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Funding

  • National Institutes of Health

    R43-CA097833; R01-CA122226

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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Pharmacology and Antitumor Activity of ABC294640, a Selective Inhibitor of Sphingosine Kinase-2

Kevin J. French, Yan Zhuang, Lynn W. Maines, Peng Gao, Wenxue Wang, Vladimir Beljanski, John J. Upson, Cecelia L. Green, Staci N. Keller and Charles D. Smith
Journal of Pharmacology and Experimental Therapeutics April 1, 2010, 333 (1) 129-139; DOI: https://doi.org/10.1124/jpet.109.163444
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