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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

P-glycoprotein and Breast Cancer Resistance Protein Influence Brain Distribution of Dasatinib

Ying Chen, Sagar Agarwal, Naveed M. Shaik, Cliff Chen, Zheng Yang and William F. Elmquist
Journal of Pharmacology and Experimental Therapeutics September 2009, 330 (3) 956-963; DOI: https://doi.org/10.1124/jpet.109.154781
Ying Chen
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Sagar Agarwal
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Naveed M. Shaik
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Cliff Chen
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Zheng Yang
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William F. Elmquist
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Article Information

vol. 330 no. 3 956-963
DOI 
https://doi.org/10.1124/jpet.109.154781
PubMed 
19491323

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 7, 2009
  • Accepted June 1, 2009
  • Published online August 20, 2009.

Article Versions

  • Earlier version (June 2, 2009 - 11:46).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Ying Chen,
  2. Sagar Agarwal,
  3. Naveed M. Shaik,
  4. Cliff Chen,
  5. Zheng Yang and
  6. William F. Elmquist
  1. Department of Pharmaceutics, University of Minnesota, Minneapolis, Minnesota (Y.C., S.A., N.M.S., W.F.E.); Metabolism and Pharmacokinetics, Pharmaceutical Candidate Optimization, Bristol-Myers Squibb Co., Princeton, New Jersey (C.C., Z.Y.)
  1. Address correspondence to:
    Dr. William F. Elmquist, Department of Pharmaceutics, 9-177 Weaver Densford Hall, University of Minnesota, 308 Harvard St. SE, Minneapolis, MN 55455. E-mail: elmqu011{at}umn.edu
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Journal of Pharmacology and Experimental Therapeutics: 381 (2)
Journal of Pharmacology and Experimental Therapeutics
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

P-glycoprotein and Breast Cancer Resistance Protein Influence Brain Distribution of Dasatinib

Ying Chen, Sagar Agarwal, Naveed M. Shaik, Cliff Chen, Zheng Yang and William F. Elmquist
Journal of Pharmacology and Experimental Therapeutics September 1, 2009, 330 (3) 956-963; DOI: https://doi.org/10.1124/jpet.109.154781

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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

P-glycoprotein and Breast Cancer Resistance Protein Influence Brain Distribution of Dasatinib

Ying Chen, Sagar Agarwal, Naveed M. Shaik, Cliff Chen, Zheng Yang and William F. Elmquist
Journal of Pharmacology and Experimental Therapeutics September 1, 2009, 330 (3) 956-963; DOI: https://doi.org/10.1124/jpet.109.154781
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