Abstract
Studies of red and white cells and hemoglobin were made on 16 dogs during addiction to morphine and after sudden withdrawal; differential counts of white cells were made on 8 dogs.
Red blood cells are normally more numerous in dog's blood than in human blood; during addiction to morphine the number of red cells is not materially altered; following abrupt withdrawal the number is decreased.
White blood cells are normally more numerous in dog's blood than in human blood; during addiction neither the number nor the relative amounts of the various forms of white cells show any consistent change; during withdrawal there is a marked leucocytosis and during the leucocytosis the percentage of polynuclear neutrophiles is increased.
The hemoglobin content of dog's blood is not altered during addiction to morphine; during withdrawal the hemoglobin is usually decreased, the fall being parallel to the decrease in red cells.
Footnotes
- Received February 3, 1928.
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