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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Metabolic Activation of Mifepristone [RU486; 17β-Hydroxy-11β-(4-dimethylaminophenyl)-17α-(1-propynyl)-estra-4,9-dien-3-one] by Mammalian Cytochromes P450 and the Mechanism-Based Inactivation of Human CYP2B6

Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics April 2009, 329 (1) 26-37; DOI: https://doi.org/10.1124/jpet.108.148536
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Metabolic Activation of Mifepristone [RU486; 17β-Hydroxy-11β-(4-dimethylaminophenyl)-17α-(1-propynyl)-estra-4,9-dien-3-one] by Mammalian Cytochromes P450 and the Mechanism-Based Inactivation of Human CYP2B6

Hsia-lien Lin, Haoming Zhang and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics April 1, 2009, 329 (1) 26-37; DOI: https://doi.org/10.1124/jpet.108.148536
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