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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3

Gerard Minuesa, Christopher Volk, Míriam Molina-Arcas, Valentin Gorboulev, Itziar Erkizia, Petra Arndt, Bonaventura Clotet, Marçal Pastor-Anglada, Hermann Koepsell and Javier Martinez-Picado
Journal of Pharmacology and Experimental Therapeutics April 2009, 329 (1) 252-261; DOI: https://doi.org/10.1124/jpet.108.146225
Gerard Minuesa
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Christopher Volk
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Míriam Molina-Arcas
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Valentin Gorboulev
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Itziar Erkizia
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Petra Arndt
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Bonaventura Clotet
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Marçal Pastor-Anglada
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Hermann Koepsell
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Javier Martinez-Picado
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Article Information

vol. 329 no. 1 252-261
DOI 
https://doi.org/10.1124/jpet.108.146225
PubMed 
19141712

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 16, 2008
  • Accepted January 12, 2009
  • Published online March 30, 2009.

Article Versions

  • Earlier version (January 13, 2009 - 11:48).
  • Earlier version (January 14, 2009 - 05:09).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Gerard Minuesa,
  2. Christopher Volk,
  3. Míriam Molina-Arcas,
  4. Valentin Gorboulev,
  5. Itziar Erkizia,
  6. Petra Arndt,
  7. Bonaventura Clotet,
  8. Marçal Pastor-Anglada,
  9. Hermann Koepsell and
  10. Javier Martinez-Picado
  1. IrsiCaixa Foundation, Hospital Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain (G.M., I.E., B.C., J.M.-P.); Institüt für Anatomie und Zellbiologie, Universität Würzburg, Würzburg, Germany (C.V., V.G., P.A., H.K.); Departament de Bioquímica i Biologia Molecular, Facultat de Biologia, Institut de Biomedicina, Universitat de Barcelona and Centro de Investigación Biomédica en Red-Enfermedades Hepáticas y Digestivas, Barcelona, Spain (M.M.-A., M.P.-A.); and Institució Catalana de Recerca i Estudis Avançats, Barcelona, Spain (J.M.-P.)
  1. Address correspondence to:
    Javier Martinez-Picado, IrsiCaixa Foundation, Hospital Germans Trias i Pujol, E-08916, Badalona, Barcelona, Spain. E-mail: jmpicado{at}irsicaixa.es
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Journal of Pharmacology and Experimental Therapeutics: 329 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 329, Issue 1
1 Apr 2009
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3

Gerard Minuesa, Christopher Volk, Míriam Molina-Arcas, Valentin Gorboulev, Itziar Erkizia, Petra Arndt, Bonaventura Clotet, Marçal Pastor-Anglada, Hermann Koepsell and Javier Martinez-Picado
Journal of Pharmacology and Experimental Therapeutics April 1, 2009, 329 (1) 252-261; DOI: https://doi.org/10.1124/jpet.108.146225

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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Transport of Lamivudine [(-)-β-l-2′,3′-Dideoxy-3′-thiacytidine] and High-Affinity Interaction of Nucleoside Reverse Transcriptase Inhibitors with Human Organic Cation Transporters 1, 2, and 3

Gerard Minuesa, Christopher Volk, Míriam Molina-Arcas, Valentin Gorboulev, Itziar Erkizia, Petra Arndt, Bonaventura Clotet, Marçal Pastor-Anglada, Hermann Koepsell and Javier Martinez-Picado
Journal of Pharmacology and Experimental Therapeutics April 1, 2009, 329 (1) 252-261; DOI: https://doi.org/10.1124/jpet.108.146225
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