Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

January 01, 2009; Volume 328,Issue 1

EDITOR'S NOTE

  • You have access
    Rick G. Schnellmann
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 1;

HIGHLIGHTED PAPERS

  • You have access
    Pentraxins as Modulators of Cocaine-Induced Synaptic Modulation
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 2;
  • You have access
    The Mechanism Behind Lecithinized Superoxide Dismutase Therapy
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 2;
  • You have access
    A Role for the Farnesoid X Receptor in Nonalcoholic Steatohepatitis
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 2;

PERSPECTIVES IN PHARMACOLOGY

  • You have access
    The Role of ATP Binding Cassette Transporters in Tissue Defense and Organ Regeneration
    Miriam Huls, Frans G. M. Russel and Rosalinde Masereeuw
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 3-9; DOI: https://doi.org/10.1124/jpet.107.132225

BEHAVIORAL PHARMACOLOGY

  • You have access
    Effects of Atypical κ-Opioid Receptor Agonists on Intrathecal Morphine-Induced Itch and Analgesia in Primates
    Mei-Chuan Ko and Stephen M. Husbands
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 193-200; DOI: https://doi.org/10.1124/jpet.108.143925
  • You have access
    M5 Muscarinic Receptor Knockout Mice Show Reduced Morphine-Induced Locomotion but Increased Locomotion after Cholinergic Antagonism in the Ventral Tegmental Area
    Stephan Steidl and John S. Yeomans
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 263-275; DOI: https://doi.org/10.1124/jpet.108.144824
  • You have access
    α1-Adrenoceptors Mediate Dihydroxyphenylalanine-Induced Activity in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Lesioned Macaques
    N. P. Visanji, S. H. Fox, T. H. Johnston, M. J. Millan and J. M. Brotchie
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 276-283; DOI: https://doi.org/10.1124/jpet.108.144097
  • You have access
    Divergent Effects of Anandamide Transporter Inhibitors with Different Target Selectivity on Social Play Behavior in Adolescent Rats
    Viviana Trezza and Louk J. M. J. Vanderschuren
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 343-350; DOI: https://doi.org/10.1124/jpet.108.141069

CARDIOVASCULAR

  • You have access
    A Novel and Orally Active Poly(ADP-Ribose) Polymerase Inhibitor, KR-33889 [2-[Methoxycarbonyl(4-methoxyphenyl) methylsulfanyl]-1H-benzimidazole-4-carboxylic Acid Amide], Attenuates Injury in in Vitro Model of Cell Death and in Vivo Model of Cardiac Ischemia
    Kwang-Seok Oh, Sunkyung Lee, Kyu Yang Yi, Ho Won Seo, Hyun-Na Koo and Byung Ho Lee
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 10-18; DOI: https://doi.org/10.1124/jpet.108.143719
  • You have access
    Hypertension Increases Contractile Responses to Hydrogen Peroxide in Resistance Arteries through Increased Thromboxane A2, Ca2+, and Superoxide Anion Levels
    Ana Belén García-Redondo, Ana María Briones, Amada Elia Beltrán, María Jesús Alonso, Ulf Simonsen and Mercedes Salaices
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 19-27; DOI: https://doi.org/10.1124/jpet.108.144295
  • You have access
    Brainstem Adenosine A1 Receptor Signaling Masks Phosphorylated Extracellular Signal-Regulated Kinase 1/2-Dependent Hypotensive Action of Clonidine in Conscious Normotensive Rats
    Noha Nassar and Abdel A. Abdel-Rahman
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 83-89; DOI: https://doi.org/10.1124/jpet.108.143883
  • You have access
    Opposite Effects of Two Resveratrol (trans-3,5,4′-Trihydroxystilbene) Tetramers, Vitisin A and Hopeaphenol, on Apoptosis of Myocytes Isolated from Adult Rat Heart
    Kazuhiko Seya, Kouta Kanemaru, Chiharu Sugimoto, Megumi Suzuki, Teruko Takeo, Shigeru Motomura, Haruo Kitahara, Masatake Niwa, Yoshiteru Oshima and Ken-Ichi Furukawa
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 90-98; DOI: https://doi.org/10.1124/jpet.108.143172
  • You have access
    Chronic Cocaine-Induced Cardiac Oxidative Stress and Mitogen-Activated Protein Kinase Activation: The Role of Nox2 Oxidase
    Lampson Fan, David Sawbridge, Vinoj George, Lei Teng, Alexis Bailey, Ian Kitchen and Jian-Mei Li
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 99-106; DOI: https://doi.org/10.1124/jpet.108.145201
  • You have access
    Distinct Roles of Estrogen Receptor-α and β in the Modulation of Vascular Inducible Nitric-Oxide Synthase in Diabetes
    Andrea Cignarella, Chiara Bolego, Valeria Pelosi, Clara Meda, Andrée Krust, Christian Pinna, Rosa Maria Gaion, Elisabetta Vegeto and Adriana Maggi
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 174-182; DOI: https://doi.org/10.1124/jpet.108.143511
  • You have access
    Increased Oxidant Activity Mediates Vascular Dysfunction in Vibration Injury
    Jennifer M. Hughes, Oliver Wirth, Kristine Krajnak, Roger Miller, Sheila Flavahan, Dan E. Berkowitz, Dan Welcome and Nicholas A. Flavahan
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 223-230; DOI: https://doi.org/10.1124/jpet.108.144618
  • You have access
    Epoxyeicosatrienoic Acids Function as Selective, Endogenous Antagonists of Native Thromboxane Receptors: Identification of a Novel Mechanism of Vasodilation
    David J. Behm, Andrea Ogbonna, Charlene Wu, Cynthia L. Burns-Kurtis and Stephen A. Douglas
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 231-239; DOI: https://doi.org/10.1124/jpet.108.145102
  • You have access
    Partial A1 Adenosine Receptor Agonist Regulates Cardiac Substrate Utilization in Insulin-Resistant Rats in Vivo
    Jane Shearer, David L. Severson, Lin Su, Luiz Belardinelli and Arvinder K. Dhalla
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 306-311; DOI: https://doi.org/10.1124/jpet.108.143594
  • You have access
    The Endogenous Brain Constituent N-Arachidonoyl l-Serine Is an Activator of Large Conductance Ca2+-Activated K+ Channels
    Grzegorz Godlewski, László Offertáler, Douglas Osei-Hyiaman, Fong Ming Mo, Judith Harvey-White, Jie Liu, Margaret I. Davis, Li Zhang, Raj K. Razdan, Garry Milman, Pal Pacher, Partha Mukhopadhyay, David M. Lovinger and George Kunos
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 351-361; DOI: https://doi.org/10.1124/jpet.108.144717

CELLULAR AND MOLECULAR

  • You have access
    Selectivity of Agonists for the Active State of M1 to M4 Muscarinic Receptor Subtypes
    Katherine W. Figueroa, Michael T. Griffin and Frederick J. Ehlert
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 331-342; DOI: https://doi.org/10.1124/jpet.108.145219

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

  • You have access
    Improved Pharmacokinetics and Efficacy of a Highly Stable Nanoliposomal Vinorelbine
    Daryl C. Drummond, Charles O. Noble, Zexiong Guo, Mark E. Hayes, John W. Park, Ching-Ju Ou, Yun-Long Tseng, Keelung Hong and Dmitri B. Kirpotin
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 321-330; DOI: https://doi.org/10.1124/jpet.108.141200

ENDOCRINE AND DIABETES

  • You have access
    Differential Effects of Diet-Induced Dyslipidemia and Hyperglycemia on Mesenteric Resistance Artery Structure and Function in Type 2 Diabetes
    Kamakshi Sachidanandam, Jim R. Hutchinson, Mostafa M. Elgebaly, Erin M. Mezzetti, Mong-Heng Wang and Adviye Ergul
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 123-130; DOI: https://doi.org/10.1124/jpet.108.142612

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

  • You have access
    Suplatast Tosilate Prevents Bleomycin-Induced Pulmonary Fibrosis in Mice
    Makoto Furonaka, Noboru Hattori, Takuya Tanimoto, Tadashi Senoo, Nobuhisa Ishikawa, Kazunori Fujitaka, Yoshinori Haruta, Akihito Yokoyama and Nobuoki Kohno
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 55-61; DOI: https://doi.org/10.1124/jpet.108.141721
  • You have access
    Sensitization by 5-Azacytidine toward Death Receptor-Induced Hepatic Apoptosis
    Timo Weiland, Markus Weiller, Gerald Künstle and Albrecht Wendel
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 107-115; DOI: https://doi.org/10.1124/jpet.108.143560
  • You have access
    Farnesoid X Receptor Deficiency Induces Nonalcoholic Steatohepatitis in Low-Density Lipoprotein Receptor-Knockout Mice Fed a High-Fat Diet
    Bo Kong, James P. Luyendyk, Ossama Tawfik and Grace L. Guo
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 116-122; DOI: https://doi.org/10.1124/jpet.108.144600
  • You have access
    Therapeutic Effect of Lecithinized Superoxide Dismutase against Colitis
    Tomoaki Ishihara, Ken-Ichiro Tanaka, Yuichi Tasaka, Takushi Namba, Jun Suzuki, Tsutomu Ishihara, Susumu Okamoto, Toshifumi Hibi, Mitsuko Takenaga, Rie Igarashi, Keizo Sato, Yutaka Mizushima and Tohru Mizushima
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 152-164; DOI: https://doi.org/10.1124/jpet.108.144451
  • You have access
    Catecholamines Relax Detrusor through β2-Adrenoceptors in Mouse and β3-Adrenoceptors in Man
    Melinda Wuest, Birgit Eichhorn, Marc O. Grimm, Manfred P. Wirth, Ursula Ravens and Alberto J. Kaumann
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 213-222; DOI: https://doi.org/10.1124/jpet.108.142562
  • You have access
    Risperidone Attenuates Local and Systemic Inflammatory Responses to Ameliorate Diet-Induced Severe Necrotic Pancreatitis in Mice: It May Provide a New Therapy for Acute Pancreatitis
    Isamu Yamaguchi, Kentaro Hamada, Masanori Yoshida, Hiroyuki Isayama, Shuichi Kanazashi and Koji Takeuchi
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 256-262; DOI: https://doi.org/10.1124/jpet.108.141895
  • You have access
    Computational Strategies Unravel and Trace How Liver Disease Changes Hepatic Drug Disposition
    Sunwoo Park, Glen E. P. Ropella, Sean H. J. Kim, Michael S. Roberts and C. Anthony Hunt
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 294-305; DOI: https://doi.org/10.1124/jpet.108.142497

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

  • You have access
    CNTO736, a Novel Glucagon-Like Peptide-1 Receptor Agonist, Ameliorates Insulin Resistance and Inhibits Very Low-Density Lipoprotein Production in High-Fat-Fed Mice
    Edwin T. Parlevliet, Janny P. Schröder-van der Elst, Eleonora P. M. Corssmit, Kristen Picha, Karyn O'Neil, Vedrana Stojanovic-Susulic, Tatiana Ort, Louis M. Havekes, Johannes A. Romijn and Hanno Pijl
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 240-248; DOI: https://doi.org/10.1124/jpet.108.144154
  • You have access
    Decreased Oral Absorption of Cyclosporine A after Liver Ischemia-Reperfusion Injury in Rats: The Contribution of CYP3A and P-Glycoprotein to the First-Pass Metabolism in Intestinal Epithelial Cells
    Kenji Ikemura, Kimihiko Urano, Hiroko Matsuda, Hideki Mizutani, Takuya Iwamoto and Masahiro Okuda
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 249-255; DOI: https://doi.org/10.1124/jpet.108.145581
  • You have access
    Novel Vasoconstrictor Formulation to Enhance Intranasal Targeting of Neuropeptide Therapeutics to the Central Nervous System
    Shyeilla V. Dhuria, Leah R. Hanson and William H. Frey
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 312-320; DOI: https://doi.org/10.1124/jpet.108.145565

NEUROPHARMACOLOGY

  • You have access
    A Positive Modulator of KCa2 and KCa3 Channels, 4,5-Dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591), Inhibits Bladder Afferent Firing in Vitro and Bladder Overactivity in Vivo
    C. Hougaard, M. O. Fraser, C. Chien, A. Bookout, M. Katofiasc, B. S. Jensen, F. Rode, J. Bitsch-Nørhave, L. Teuber, K. B. Thor, D. Strøbæk, E. C. Burgard and L. C. B. Rønn
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 28-39; DOI: https://doi.org/10.1124/jpet.108.143123
  • You have access
    Ligand Selectivity of D2 Dopamine Receptors Is Modulated by Changes in Local Dynamics Produced by Sodium Binding
    Spencer S. Ericksen, David F. Cummings, Harel Weinstein and John A. Schetz
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 40-54; DOI: https://doi.org/10.1124/jpet.108.141531
  • You have access
    A Single in Vivo Application of Cholinesterase Inhibitors Has Neuron Type-Specific Effects on Nicotinic Receptor Activity in Guinea Pig Hippocampus
    Manickavasagom Alkondon, Yasco Aracava, Edna F. R. Pereira and Edson X. Albuquerque
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 69-82; DOI: https://doi.org/10.1124/jpet.108.146068
  • You have access
    First Demonstration of Cerebrospinal Fluid and Plasma Aβ Lowering with Oral Administration of a β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitor in Nonhuman Primates
    Sethu Sankaranarayanan, Marie A. Holahan, Dennis Colussi, Ming-Chih Crouthamel, Viswanath Devanarayan, Joan Ellis, Amy Espeseth, Adam T. Gates, Samuel L. Graham, Allison R. Gregro, Daria Hazuda, Jerome H. Hochman, Katharine Holloway, Lixia Jin, Jason Kahana, Ming-tain Lai, Janet Lineberger, Georgia McGaughey, Keith P. Moore, Philippe Nantermet, Beth Pietrak, Eric A. Price, Hemaka Rajapakse, Shaun Stauffer, Melissa A. Steinbeiser, Guy Seabrook, Harold G. Selnick, Xiao-Ping Shi, Matthew G. Stanton, John Swestock, Katherine Tugusheva, Keala X. Tyler, Joseph P. Vacca, Jacky Wong, Guoxin Wu, Min Xu, Jacquelynn J. Cook and Adam J. Simon
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 131-140; DOI: https://doi.org/10.1124/jpet.108.143628
  • You have access
    Characterization of a Cannabinoid CB2 Receptor-Selective Agonist, A-836339 [2,2,3,3-Tetramethyl-cyclopropanecarboxylic Acid [3-(2-Methoxy-ethyl)-4,5-dimethyl-3H-thiazol-(2Z)-ylidene]-amide], Using in Vitro Pharmacological Assays, in Vivo Pain Models, and Pharmacological Magnetic Resonance Imaging
    Betty B. Yao, Gin Hsieh, Anthony V. Daza, Yihong Fan, George K. Grayson, Tiffany Runyan Garrison, Odile El Kouhen, Bradley A. Hooker, Madhavi Pai, Erica J. Wensink, Anita K. Salyers, Prasant Chandran, Chang Z. Zhu, Chengmin Zhong, Keith Ryther, Megan E. Gallagher, Chih-Liang Chin, Ann E. Tovcimak, Vincent P. Hradil, Gerard B. Fox, Michael J. Dart, Prisca Honore and Michael D. Meyer
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 141-151; DOI: https://doi.org/10.1124/jpet.108.145011
  • You have access
    The Role of Melanin-Concentrating Hormone-1 Receptors in the Voiding Reflex in Rats
    Laxminarayan G. Hegde, Xiao Li Ping, Nina Jochnowitz and Douglas A. Craig
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 165-173; DOI: https://doi.org/10.1124/jpet.108.143495
  • You have access
    Neuronal Pentraxins Modulate Cocaine-Induced Neuroadaptations
    Alejandra M. Pacchioni, Joseph Vallone, Paul F. Worley and Peter W. Kalivas
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 183-192; DOI: https://doi.org/10.1124/jpet.108.143115
  • You have access
    Modulation of Sodium Channel Inactivation Gating by a Novel Lactam: Implications for Seizure Suppression in Chronic Limbic Epilepsy
    Paulianda J. Jones, Ellen C. Merrick, Timothy W. Batts, Nicholas J. Hargus, Yuesheng Wang, James P. Stables, Edward H. Bertram, Milton L. Brown and Manoj K. Patel
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 201-212; DOI: https://doi.org/10.1124/jpet.108.144709
  • You have access
    μ-Opioid Receptors Selectively Regulate Basal Inhibitory Transmission in the Central Amygdala: Lack of Ethanol Interactions
    Maeng-Hee Kang-Park, Brigitte L. Kieffer, Amanda J. Roberts, Marisa Roberto, Samuel G. Madamba, George Robert Siggins and Scott D. Moore
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 284-293; DOI: https://doi.org/10.1124/jpet.108.140749

TOXICOLOGY

  • You have access
    Tumor Necrosis Factorα Is a Proximal Mediator of Synergistic Hepatotoxicity from Trovafloxacin/Lipopolysaccharide Coexposure
    Patrick J. Shaw, Patricia E. Ganey and Robert A. Roth
    Journal of Pharmacology and Experimental Therapeutics January 2009, 328 (1) 62-68; DOI: https://doi.org/10.1124/jpet.108.143792
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 328 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 328, Issue 1
1 Jan 2009
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • EDITOR'S NOTE
  • HIGHLIGHTED PAPERS
  • PERSPECTIVES IN PHARMACOLOGY
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • ENDOCRINE AND DIABETES
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • METABOLISM, TRANSPORT, AND PHARMACOGENOMICS
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
  • Most Read
Loading
  • Smoking Could Worsen COVID-19 Outcome
  • KBP-042 as Adjunct Therapy to Metformin
  • SARS-CoV-2 Drug Discovery
  • Potential Clinical Uses of CBG
  • Nose-to-Brain Delivery
More...
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics