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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress

Cara A. Rabik, Melissa L. Fishel, Julianne L. Holleran, Kristen Kasza, Mark R. Kelley, Merrill J. Egorin and M. Eileen Dolan
Journal of Pharmacology and Experimental Therapeutics November 2008, 327 (2) 442-452; DOI: https://doi.org/10.1124/jpet.108.141291
Cara A. Rabik
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Melissa L. Fishel
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Julianne L. Holleran
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Kristen Kasza
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Mark R. Kelley
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Merrill J. Egorin
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M. Eileen Dolan
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Article Information

vol. 327 no. 2 442-452
DOI 
https://doi.org/10.1124/jpet.108.141291
PubMed 
18664592

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received May 20, 2008
  • Accepted July 28, 2008
  • Published online October 17, 2008.

Article Versions

  • Earlier version (July 29, 2008 - 09:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Cara A. Rabik,
  2. Melissa L. Fishel,
  3. Julianne L. Holleran,
  4. Kristen Kasza,
  5. Mark R. Kelley,
  6. Merrill J. Egorin and
  7. M. Eileen Dolan
  1. Departments of Molecular Genetics and Cell Biology (C.A.R.), Health Studies (K.K.), and Medicine (M.E.D.), University of Chicago, Chicago, Illinois; Department of Pediatrics, Herman B. Wells Center for Pediatric Research (M.L.F., M.R.K.) and Departments of Pharmacology and Toxicology and Biochemistry and Molecular Biology (M.R.K.), Indiana University School of Medicine, Indianapolis, Indiana; and Departments of Medicine, Pharmacology, and Cancer Institute, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania (J.L.H., M.J.E.)
  1. Address correspondence to:
    Dr. M. Eileen Dolan, 5841 S. Maryland Ave., Box MC2115, University of Chicago, Chicago, IL 60637. E-mail: edolan{at}medicine.bsd.uchicago.edu
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Journal of Pharmacology and Experimental Therapeutics: 384 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 384, Issue 2
1 Feb 2023
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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress

Cara A. Rabik, Melissa L. Fishel, Julianne L. Holleran, Kristen Kasza, Mark R. Kelley, Merrill J. Egorin and M. Eileen Dolan
Journal of Pharmacology and Experimental Therapeutics November 1, 2008, 327 (2) 442-452; DOI: https://doi.org/10.1124/jpet.108.141291

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Research ArticleCHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

Enhancement of Cisplatin [cis-Diammine Dichloroplatinum (II)] Cytotoxicity by O6-Benzylguanine Involves Endoplasmic Reticulum Stress

Cara A. Rabik, Melissa L. Fishel, Julianne L. Holleran, Kristen Kasza, Mark R. Kelley, Merrill J. Egorin and M. Eileen Dolan
Journal of Pharmacology and Experimental Therapeutics November 1, 2008, 327 (2) 442-452; DOI: https://doi.org/10.1124/jpet.108.141291
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