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Research ArticleNEUROPHARMACOLOGY

Pharmacological Effects of the Metabotropic Glutamate Receptor 1 Antagonist Compared with Those of the Metabotropic Glutamate Receptor 5 Antagonist and Metabotropic Glutamate Receptor 2/3 Agonist in Rodents: Detailed Investigations with a Selective Allosteric Metabotropic Glutamate Receptor 1 Antagonist, FTIDC [4-[1-(2-Fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]

Akio Satow, Shunsuke Maehara, Satoko Ise, Hirohiko Hikichi, Miyuki Fukushima, Gentaroh Suzuki, Toshifumi Kimura, Takeshi Tanaka, Satoru Ito, Hiroshi Kawamoto and Hisashi Ohta
Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 577-586; DOI: https://doi.org/10.1124/jpet.108.138107

Article Information

vol. 326 no. 2 577-586
DOI 
https://doi.org/10.1124/jpet.108.138107
PubMed 
18487514
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 18, 2008
  • Accepted May 16, 2008
  • Published online July 18, 2008.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Akio Satow,
  2. Shunsuke Maehara,
  3. Satoko Ise,
  4. Hirohiko Hikichi,
  5. Miyuki Fukushima,
  6. Gentaroh Suzuki,
  7. Toshifumi Kimura,
  8. Takeshi Tanaka,
  9. Satoru Ito,
  10. Hiroshi Kawamoto and
  11. Hisashi Ohta
  1. Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., Tsukuba, Japan
  1. Address correspondence to:
    Akio Satow, Tsukuba Research Institute, Banyu Pharmaceutical Co., Ltd., 3 Okubo, Tsukuba, Ibaraki 300-2611, Japan. E-mail: akio_sato{at}merck.com
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Research ArticleNEUROPHARMACOLOGY

Pharmacological Effects of the Metabotropic Glutamate Receptor 1 Antagonist Compared with Those of the Metabotropic Glutamate Receptor 5 Antagonist and Metabotropic Glutamate Receptor 2/3 Agonist in Rodents: Detailed Investigations with a Selective Allosteric Metabotropic Glutamate Receptor 1 Antagonist, FTIDC [4-[1-(2-Fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]

Akio Satow, Shunsuke Maehara, Satoko Ise, Hirohiko Hikichi, Miyuki Fukushima, Gentaroh Suzuki, Toshifumi Kimura, Takeshi Tanaka, Satoru Ito, Hiroshi Kawamoto and Hisashi Ohta
Journal of Pharmacology and Experimental Therapeutics August 1, 2008, 326 (2) 577-586; DOI: https://doi.org/10.1124/jpet.108.138107
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