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Research ArticleCardiovascular

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

Robert N. Willette, Weike Bao, Sandhya Nerurkar, Tian-li Yue, Chris P. Doe, Gerald Stankus, Gregory H. Turner, Haisong Ju, Heath Thomas, Cindy E. Fishman, Anthony Sulpizio, David J. Behm, Sandra Hoffman, Zuojun Lin, Irina Lozinskaya, Linda N. Casillas, Min Lin, Robert E. Lee Trout, Bartholomew J. Votta, Kevin Thorneloe, Erin S. R. Lashinger, David J. Figueroa, Robert Marquis and Xiaoping Xu
Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 443-452; DOI: https://doi.org/10.1124/jpet.107.134551
Robert N. Willette
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Weike Bao
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Sandhya Nerurkar
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Tian-li Yue
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Chris P. Doe
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Gerald Stankus
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Gregory H. Turner
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Haisong Ju
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Heath Thomas
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Cindy E. Fishman
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Anthony Sulpizio
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David J. Behm
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Sandra Hoffman
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Zuojun Lin
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Irina Lozinskaya
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Linda N. Casillas
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Min Lin
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Robert E. Lee Trout
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Bartholomew J. Votta
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Kevin Thorneloe
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Erin S. R. Lashinger
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David J. Figueroa
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Robert Marquis
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Xiaoping Xu
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Article Information

vol. 326 no. 2 443-452
DOI 
https://doi.org/10.1124/jpet.107.134551
PubMed 
18499744

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received November 20, 2007
  • Accepted May 6, 2008
  • Published online July 18, 2008.

Article Versions

  • Earlier version (May 22, 2008 - 11:21).
  • Earlier version (May 27, 2008 - 04:38).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2008 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Robert N. Willette,
  2. Weike Bao,
  3. Sandhya Nerurkar,
  4. Tian-li Yue,
  5. Chris P. Doe,
  6. Gerald Stankus,
  7. Gregory H. Turner,
  8. Haisong Ju,
  9. Heath Thomas,
  10. Cindy E. Fishman,
  11. Anthony Sulpizio,
  12. David J. Behm,
  13. Sandra Hoffman,
  14. Zuojun Lin,
  15. Irina Lozinskaya,
  16. Linda N. Casillas,
  17. Min Lin,
  18. Robert E. Lee Trout,
  19. Bartholomew J. Votta,
  20. Kevin Thorneloe,
  21. Erin S. R. Lashinger,
  22. David J. Figueroa,
  23. Robert Marquis and
  24. Xiaoping Xu
  1. Cardiovascular-Urogenital (R.N.W., W.B., S.N., T.-l.Y., C.P.D., G.S., G.H.T., A.S., D.J.B., Z.L., I.L., K.T., E.S.R.L., D.J.F., X.X.) and Oncology (S.H., L.N.C., M.L., R.E.L.T., B.J.V., R.M.) Centers of Excellence in Drug Discovery, Safety Assessment (H.J., H.T., C.E.F.), GlaxoSmithKline Pharmaceuticals, King of Prussia, Pennsylvania
  1. Address correspondence to:
    Dr. Robert N. Willette, Investigative and Cardiac Biology, GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, UW2510, King of Prussia, PA 19406. E-mail: robert.n.willette{at}gsk.com
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Journal of Pharmacology and Experimental Therapeutics: 326 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 326, Issue 2
1 Aug 2008
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Research ArticleCardiovascular

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

Robert N. Willette, Weike Bao, Sandhya Nerurkar, Tian-li Yue, Chris P. Doe, Gerald Stankus, Gregory H. Turner, Haisong Ju, Heath Thomas, Cindy E. Fishman, Anthony Sulpizio, David J. Behm, Sandra Hoffman, Zuojun Lin, Irina Lozinskaya, Linda N. Casillas, Min Lin, Robert E. Lee Trout, Bartholomew J. Votta, Kevin Thorneloe, Erin S. R. Lashinger, David J. Figueroa, Robert Marquis and Xiaoping Xu
Journal of Pharmacology and Experimental Therapeutics August 1, 2008, 326 (2) 443-452; DOI: https://doi.org/10.1124/jpet.107.134551

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Research ArticleCardiovascular

Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2

Robert N. Willette, Weike Bao, Sandhya Nerurkar, Tian-li Yue, Chris P. Doe, Gerald Stankus, Gregory H. Turner, Haisong Ju, Heath Thomas, Cindy E. Fishman, Anthony Sulpizio, David J. Behm, Sandra Hoffman, Zuojun Lin, Irina Lozinskaya, Linda N. Casillas, Min Lin, Robert E. Lee Trout, Bartholomew J. Votta, Kevin Thorneloe, Erin S. R. Lashinger, David J. Figueroa, Robert Marquis and Xiaoping Xu
Journal of Pharmacology and Experimental Therapeutics August 1, 2008, 326 (2) 443-452; DOI: https://doi.org/10.1124/jpet.107.134551
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