Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

August 01, 2008; Volume 326,Issue 2

PERSPECTIVES IN PHARMACOLOGY

  • You have access
    Mineral Arsenicals in Traditional Medicines: Orpiment, Realgar, and Arsenolite
    Jie Liu, Yuanfu Lu, Qin Wu, Robert A. Goyer and Michael P. Waalkes
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 363-368; DOI: https://doi.org/10.1124/jpet.108.139543

BEHAVIORAL PHARMACOLOGY

  • You have access
    Specific Antinociceptive Activity of Cholest-4-en-3-one, Oxime (TRO19622) in Experimental Models of Painful Diabetic and Chemotherapy-Induced Neuropathy
    Thierry Bordet, Bruno Buisson, Magali Michaud, Jean-Louis Abitbol, Fabien Marchand, John Grist, Emile Andriambeloson, Marzia Malcangio and Rebecca M. Pruss
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 623-632; DOI: https://doi.org/10.1124/jpet.108.139410
  • You have access
    Spinal Antiallodynia Action of Glycine Transporter Inhibitors in Neuropathic Pain Models in Mice
    Katsuya Morita, Naoyo Motoyama, Tomoya Kitayama, Norimitsu Morioka, Koki Kifune and Toshihiro Dohi
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 633-645; DOI: https://doi.org/10.1124/jpet.108.136267
  • You have access
    The Anxiolytic-Like Effects of the Novel, Orally Active Nociceptin Opioid Receptor Agonist 8-[bis(2-Methylphenyl)methyl]-3-phenyl-8-azabicyclo[3.2.1]octan-3-ol (SCH 221510)
    Geoffrey B. Varty, Sherry X. Lu, Cynthia A. Morgan, Mary E. Cohen-Williams, Robert A. Hodgson, April Smith-Torhan, Hongtao Zhang, Ahmad B. Fawzi, Michael P. Graziano, Ginny D. Ho, Julius Matasi, Deen Tulshian, Vicki L. Coffin and Galen J. Carey
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 672-682; DOI: https://doi.org/10.1124/jpet.108.136937

CARDIOVASCULAR

  • You have access
    Sustained Soluble Guanylate Cyclase Stimulation Offsets Nitric-Oxide Synthase Inhibition to Restore Acute Cardiac Modulation by Sildenafil
    Takahiro Nagayama, Manling Zhang, Steven Hsu, Eiki Takimoto and David A. Kass
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 380-387; DOI: https://doi.org/10.1124/jpet.108.137422
  • You have access
    2-Aminopurine Inhibits Lipid Accumulation Induced by Apolipoprotein E-Deficient Lipoprotein in Macrophages: Potential Role of Eukaryotic Initiation Factor-2α Phosphorylation in Foam Cell Formation
    DongFang Wu, Hong Yang, YanFeng Zhao, Chakradhari Sharan, J. Shawn Goodwin, Lichun Zhou, Yang Guo and ZhongMao Guo
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 395-405; DOI: https://doi.org/10.1124/jpet.107.134833
  • You have access
    Effects of Novel Vasopressin Receptor Antagonists on Renal Function and Cardiac Hypertrophy in Rats with Experimental Congestive Heart Failure
    Bishara Bishara, Hiba Shiekh, Tony Karram, Irit Rubinstein, Zaher S. Azzam, Niroz Abu-Saleh, Samy Nitecki, Joseph Winaver, Aaron Hoffman and Zaid A. Abassi
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 414-422; DOI: https://doi.org/10.1124/jpet.108.137745

CELLULAR AND MOLECULAR

  • You have access
    Arsenic Trioxide, Arsenic Pentoxide, and Arsenic Iodide Inhibit Human Keratinocyte Proliferation through the Induction of Apoptosis
    Wai-Pui Tse, Christopher H. K. Cheng, Chun-Tao Che and Zhi-Xiu Lin
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 388-394; DOI: https://doi.org/10.1124/jpet.107.134080
  • You have access
    Autoregulation of McA-RH7777 Hepatoma Cell Proliferation by Histamine H3 Receptors
    E. Davenas, A. Rouleau, S. Morisset and J. M. Arrang
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 406-413; DOI: https://doi.org/10.1124/jpet.107.135368
  • You have access
    Derivatized 2-Furoyl-LIGRLO-amide, a Versatile and Selective Probe for Proteinase-Activated Receptor 2: Binding and Visualization
    Morley D. Hollenberg, Bernard Renaux, Eric Hyun, Steeve Houle, Nathalie Vergnolle, Mahmoud Saifeddine and Rithwik Ramachandran
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 453-462; DOI: https://doi.org/10.1124/jpet.108.136432

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

  • You have access
    Point Mutation of the Proteasome β5 Subunit Gene Is an Important Mechanism of Bortezomib Resistance in Bortezomib-Selected Variants of Jurkat T Cell Lymphoblastic Lymphoma/Leukemia Line
    Shuqing Lü, Jianmin Yang, Xianmin Song, Shenglan Gong, Hong Zhou, Lieping Guo, Ningxia Song, Xiaochen Bao, Pingping Chen and Jianmin Wang
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 423-431; DOI: https://doi.org/10.1124/jpet.108.138131

Cardiovascular

  • You have access
    Systemic Activation of the Transient Receptor Potential Vanilloid Subtype 4 Channel Causes Endothelial Failure and Circulatory Collapse: Part 2
    Robert N. Willette, Weike Bao, Sandhya Nerurkar, Tian-li Yue, Chris P. Doe, Gerald Stankus, Gregory H. Turner, Haisong Ju, Heath Thomas, Cindy E. Fishman, Anthony Sulpizio, David J. Behm, Sandra Hoffman, Zuojun Lin, Irina Lozinskaya, Linda N. Casillas, Min Lin, Robert E. Lee Trout, Bartholomew J. Votta, Kevin Thorneloe, Erin S. R. Lashinger, David J. Figueroa, Robert Marquis and Xiaoping Xu
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 443-452; DOI: https://doi.org/10.1124/jpet.107.134551

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

  • You have access
    Topical Implantation of Mesenchymal Stem Cells Has Beneficial Effects on Healing of Experimental Colitis in Rats
    Yujiro Hayashi, Shingo Tsuji, Masahiko Tsujii, Tsutomu Nishida, Shuji Ishii, Hideki Iijima, Toru Nakamura, Hiroshi Eguchi, Eiji Miyoshi, Norio Hayashi and Sunao Kawano
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 523-531; DOI: https://doi.org/10.1124/jpet.108.137083

Gastrointestinal, Hepatic, Pulmonary, and Renal

  • You have access
    N-((1S)-1-{[4-((2S)-2-{[(2,4-Dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a Novel and Potent Transient Receptor Potential Vanilloid 4 Channel Agonist Induces Urinary Bladder Contraction and Hyperactivity: Part I
    Kevin S. Thorneloe, Anthony C. Sulpizio, Zuojun Lin, David J. Figueroa, Angela K. Clouse, Gerald P. McCafferty, Tim P. Chendrimada, Erin S. R. Lashinger, Earl Gordon, Louise Evans, Blake A. Misajet, Douglas J. DeMarini, Josephine H. Nation, Linda N. Casillas, Robert W. Marquis, Bartholomew J. Votta, Steven A. Sheardown, Xiaoping Xu, David P. Brooks, Nicholas J. Laping and Timothy D. Westfall
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 432-442; DOI: https://doi.org/10.1124/jpet.108.139295

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA

  • You have access
    Lipopolysaccharide Induces Macrophage Migration via Prostaglandin D2 and Prostaglandin E2
    Tsuyoshi Tajima, Takahisa Murata, Kosuke Aritake, Yoshihiro Urade, Hiroyuki Hirai, Masataka Nakamura, Hiroshi Ozaki and Masatoshi Hori
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 493-501; DOI: https://doi.org/10.1124/jpet.108.137992
  • You have access
    Compounds That Increase or Mimic Cyclic Adenosine Monophosphate Enhance Tristetraprolin Degradation in Lipopolysaccharide-Treated Murine J774 Macrophages
    Ulla Jalonen, Erja-Leena Paukkeri and Eeva Moilanen
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 514-522; DOI: https://doi.org/10.1124/jpet.107.133702
  • You have access
    Modeling Corticosteroid Effects in a Rat Model of Rheumatoid Arthritis I: Mechanistic Disease Progression Model for the Time Course of Collagen-Induced Arthritis in Lewis Rats
    Justin C. Earp, Debra C. DuBois, Diana S. Molano, Nancy A. Pyszczynski, Craig E. Keller, Richard R. Almon and William J. Jusko
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 532-545; DOI: https://doi.org/10.1124/jpet.108.137372
  • You have access
    Modeling Corticosteroid Effects in a Rat Model of Rheumatoid Arthritis II: Mechanistic Pharmacodynamic Model for Dexamethasone Effects in Lewis Rats with Collagen-Induced Arthritis
    Justin C. Earp, Debra C. DuBois, Diana S. Molano, Nancy A. Pyszczynski, Richard R. Almon and William J. Jusko
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 546-554; DOI: https://doi.org/10.1124/jpet.108.137414
  • You have access
    Integrated Cellular Bone Homeostasis Model for Denosumab Pharmacodynamics in Multiple Myeloma Patients
    Anshu Marathe, Mark C. Peterson and Donald E. Mager
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 555-562; DOI: https://doi.org/10.1124/jpet.108.137703

NEUROPHARMACOLOGY

  • You have access
    Reversal of Oxidative Stress-Induced Anxiety by Inhibition of Phosphodiesterase-2 in Mice
    Anbrin Masood, Ahmed Nadeem, S. Jamal Mustafa and James M. O'Donnell
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 369-379; DOI: https://doi.org/10.1124/jpet.108.137208
  • You have access
    Ethanol Modulates Synaptic and Extrasynaptic GABAA Receptors in the Thalamus
    Fan Jia, Dev Chandra, Gregg E. Homanics and Neil L. Harrison
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 475-482; DOI: https://doi.org/10.1124/jpet.108.139303
  • You have access
    The Endogenous Cannabinoid System Modulates Nicotine Reward and Dependence
    Lisa L. Merritt, B. R. Martin, C. Walters, A. H. Lichtman and M. Imad Damaj
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 483-492; DOI: https://doi.org/10.1124/jpet.108.138321
  • You have access
    P-Glycoprotein Efflux and Other Factors Limit Brain Amyloid β Reduction by β-Site Amyloid Precursor Protein-Cleaving Enzyme 1 Inhibitors in Mice
    Jere E. Meredith, Lorin A. Thompson, Jeremy H. Toyn, Lawrence Marcin, Donna M. Barten, Jovita Marcinkeviciene, Lisa Kopcho, Young Kim, Alan Lin, Valerie Guss, Catherine Burton, Lawrence Iben, Craig Polson, Joe Cantone, Michael Ford, Dieter Drexler, Tracey Fiedler, Kimberley A. Lentz, James E. Grace, Janet Kolb, Jason Corsa, Maria Pierdomenico, Kelli Jones, Richard E. Olson, John E. Macor and Charles F. Albright
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 502-513; DOI: https://doi.org/10.1124/jpet.108.138974
  • You have access
    N,N′-Alkane-diyl-bis-3-picoliniums as Nicotinic Receptor Antagonists: Inhibition of Nicotine-Evoked Dopamine Release and Hyperactivity
    Linda P. Dwoskin, Thomas E. Wooters, Sangeetha P. Sumithran, Kiran B. Siripurapu, B. Matthew Joyce, Paul R. Lockman, Vamshi K. Manda, Joshua T. Ayers, Zhenfa Zhang, Agripina G. Deaciuc, J. Michael McIntosh, Peter A. Crooks and Michael T. Bardo
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 563-576; DOI: https://doi.org/10.1124/jpet.108.136630
  • You have access
    Pharmacological Effects of the Metabotropic Glutamate Receptor 1 Antagonist Compared with Those of the Metabotropic Glutamate Receptor 5 Antagonist and Metabotropic Glutamate Receptor 2/3 Agonist in Rodents: Detailed Investigations with a Selective Allosteric Metabotropic Glutamate Receptor 1 Antagonist, FTIDC [4-[1-(2-Fluoropyridine-3-yl)-5-methyl-1H-1,2,3-triazol-4-yl]-N-isopropyl-N-methyl-3,6-dihydropyridine-1(2H)-carboxamide]
    Akio Satow, Shunsuke Maehara, Satoko Ise, Hirohiko Hikichi, Miyuki Fukushima, Gentaroh Suzuki, Toshifumi Kimura, Takeshi Tanaka, Satoru Ito, Hiroshi Kawamoto and Hisashi Ohta
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 577-586; DOI: https://doi.org/10.1124/jpet.108.138107
  • You have access
    In Vivo Characterization of a Novel Phenylisothiocyanate Tropane Analog at Monoamine Transporters in Rat Brain
    Vishakantha Murthy, Thomas J. Martin, Susy Kim, Huw M. L. Davies and Steven R. Childers
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 587-595; DOI: https://doi.org/10.1124/jpet.108.138842
  • You have access
    Brain Regional Differences in the Effect of Ethanol on GABA Release from Presynaptic Terminals
    Hugh E. Criswell, Zhen Ming, M. Katherine Kelm and George R. Breese
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 596-603; DOI: https://doi.org/10.1124/jpet.107.135418
  • You have access
    Antinociception Produced by 14,15-Epoxyeicosatrienoic Acid Is Mediated by the Activation of β-Endorphin and Met-Enkephalin in the Rat Ventrolateral Periaqueductal Gray
    Maia Terashvili, Leon F. Tseng, Hsiang-en Wu, Jayashree Narayanan, Lucas M. Hart, John R. Falck, Phillip F. Pratt and David R. Harder
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 614-622; DOI: https://doi.org/10.1124/jpet.108.136739
  • You have access
    Neuroprotective Effects of the Novel Glutamate Transporter Inhibitor (–)-3-Hydroxy-4,5,6,6a-tetrahydro-3aH-pyrrolo[3,4-d]-isoxazole-4-carboxylic Acid, Which Preferentially Inhibits Reverse Transport (Glutamate Release) Compared with Glutamate Reuptake
    Simona Colleoni, Anders A. Jensen, Elisa Landucci, Elena Fumagalli, Paola Conti, Andrea Pinto, Marco De Amici, Domenico E. Pellegrini-Giampietro, Carlo De Micheli, Tiziana Mennini and Marco Gobbi
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 646-656; DOI: https://doi.org/10.1124/jpet.107.135251

TOXICOLOGY

  • You have access
    2,3,7,8-Tetrachlorodibenzo-p-dioxin-Mediated Impairment of B Cell Differentiation Involves Dysregulation of Paired Box 5 (Pax5) Isoform, Pax5a
    Dina Schneider, Maria A. Manzan, Robert B. Crawford, Weimin Chen and Norbert E. Kaminski
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 463-474; DOI: https://doi.org/10.1124/jpet.108.139857
  • You have access
    Influence of Lipid-Soluble Gating Modifier Toxins on Sodium Influx in Neocortical Neurons
    Zhengyu Cao, Joju George, William H. Gerwick, Daniel G. Baden, Jon D. Rainier and Thomas F. Murray
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 604-613; DOI: https://doi.org/10.1124/jpet.108.138230
  • You have access
    Identification of the Thiophene Ring of Methapyrilene as a Novel Bioactivation-Dependent Hepatic Toxicophore
    Emma E. Graham, Rachel J. Walsh, Charlotte M. Hirst, James L. Maggs, Scott Martin, Martin J. Wild, Ian D. Wilson, John R. Harding, J. Gerald Kenna, Raimund M. Peter, Dominic P. Williams and B. Kevin Park
    Journal of Pharmacology and Experimental Therapeutics August 2008, 326 (2) 657-671; DOI: https://doi.org/10.1124/jpet.107.135483
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 326 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 326, Issue 2
1 Aug 2008
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Back Matter (PDF)
  • Editorial Board (PDF)
  • Front Matter (PDF)
Sign up for alerts

Jump to

  • PERSPECTIVES IN PHARMACOLOGY
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • Cardiovascular
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • Gastrointestinal, Hepatic, Pulmonary, and Renal
  • INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics