Table of Contents

NEUROPHARMACOLOGY

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  Effects of Palmitoylethanolamide on Signaling Pathways Implicated in the Development of Spinal Cord Injury

  Tiziana Genovese, Emanuela Esposito, Emanuela Mazzon, Rosanna Di Paola, Rosaria Meli, Placido Bramanti, Daniele Piomelli, Antonio Calignano and Salvatore Cuzzocrea

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 12-23; DOI: https://doi.org/10.1124/jpet.108.136903
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  Nicotinic Acetylcholine Receptors in the Anterior, but Not Posterior, Ventral Tegmental Area Mediate Ethanol-Induced Elevation of Accumbal Dopamine Levels

  Mia Ericson, Elin Löf, Rosita Stomberg, PeiPei Chau and Bo Söderpalm

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 76-82; DOI: https://doi.org/10.1124/jpet.108.137489
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  Differential Block of Sensory Neuronal Voltage-Gated Sodium Channels by Lacosamide [(2R)-2-(Acetylamino)-N-benzyl-3-methoxypropanamide], Lidocaine, and Carbamazepine

  Patrick L. Sheets, Cara Heers, Thomas Stoehr and Theodore R. Cummins

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 89-99; DOI: https://doi.org/10.1124/jpet.107.133413
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  Spiro[imidazo[1,2-a]pyridine-3,2-indan]-2(3H)-one (ZSET1446/ST101) Treatment Rescues Olfactory Bulbectomy-Induced Memory Impairment by Activating Ca²⁺/Calmodulin Kinase II and Protein Kinase C in Mouse Hippocampus

  Feng Han, Norifumi Shioda, Shigeki Moriguchi, Yui Yamamoto, Alisa Y. Ali Raie, Yoshimasa Yamaguchi, Masataka Hino and Kohji Fukunaga

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 127-134; DOI: https://doi.org/10.1124/jpet.108.137471
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  Transglutaminase-Catalyzed Transamidation: A Novel Mechanism for Rac1 Activation by 5-Hydroxytryptamine_2A Receptor Stimulation

  Y. Dai, N. L. Dudek, T. B. Patel and N. A. Muma

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 153-162; DOI: https://doi.org/10.1124/jpet.107.135046
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  Curcumin Structure-Function, Bioavailability, and Efficacy in Models of Neuroinflammation and Alzheimer's Disease

  Aynun N. Begum, Mychica R. Jones, Giselle P. Lim, Takashi Morihara, Peter Kim, Dennis D. Heath, Cheryl L. Rock, Mila A. Pruitt, Fusheng Yang, Beverly Hudspeth, Shuxin Hu, Kym F. Faull, Bruce Teter, Greg M. Cole and Sally A. Frautschy

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 196-208; DOI: https://doi.org/10.1124/jpet.108.137455
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  Evidence for the Role of Metabotropic Glutamate (mGlu)2 Not mGlu3 Receptors in the Preclinical Antipsychotic Pharmacology of the mGlu2/3 Receptor Agonist (–)-(1R,4S,5S,6S)-4-Amino-2-sulfonylbicyclo[3.1.0]hexane-4,6-dicarboxylic Acid (LY404039)

  Matthew J. Fell, Kjell A. Svensson, Bryan G. Johnson and Darryle D. Schoepp

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 209-217; DOI: https://doi.org/10.1124/jpet.108.136861
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  Antihyperalgesic Effects of (R,E)-N-(2-Hydroxy-2,3-dihydro-1H-inden-4-yl)-3-(2-(piperidin-1-yl)-4-(trifluoromethyl)phenyl)-acrylamide (AMG8562), a Novel Transient Receptor Potential Vanilloid Type 1 Modulator That Does Not Cause Hyperthermia in Rats

  Sonya G. Lehto, Rami Tamir, Hong Deng, Lana Klionsky, Rongzhen Kuang, April Le, Doo Lee, Jean-Claude Louis, Ella Magal, Barton H. Manning, John Rubino, Sekhar Surapaneni, Nuria Tamayo, Tingrong Wang, Judy Wang, Jue Wang, Weiya Wang, Brad Youngblood, Maosheng Zhang, Dawn Zhu, Mark H. Norman and Narender R. Gavva

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 218-229; DOI: https://doi.org/10.1124/jpet.107.132233
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  Transposition of Three Amino Acids Transforms the Human Metabotropic Glutamate Receptor (mGluR)-3-Positive Allosteric Modulation Site to mGluR2, and Additional Characterization of the mGluR2-Positive Allosteric Modulation Site

  Blake A. Rowe, Hervé Schaffhauser, Sylvia Morales, Laura S. Lubbers, Celine Bonnefous, Theodore M. Kamenecka, Jeffrey McQuiston and Lorrie P. Daggett

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 240-251; DOI: https://doi.org/10.1124/jpet.108.138271
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  n-Alcohols Inhibit Voltage-Gated Na⁺ Channels Expressed in Xenopus Oocytes

  Takafumi Horishita and R. Adron Harris

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 270-277; DOI: https://doi.org/10.1124/jpet.108.138370
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  Studies of the Biogenic Amine Transporters. 12. Identification of Novel Partial Inhibitors of Amphetamine-Induced Dopamine Release

  Joseph J. Pariser, John S. Partilla, Christina M. Dersch, Subramaniam Ananthan and Richard B. Rothman

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 286-295; DOI: https://doi.org/10.1124/jpet.108.139675
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  Positive Modulation of GABA_B Receptors Decreased Nicotine Self-Administration and Counteracted Nicotine-Induced Enhancement of Brain Reward Function in Rats

  Neil E. Paterson, Styliani Vlachou, Sebastien Guery, Klemens Kaupmann, Wolfgang Froestl and Athina Markou

  Journal of Pharmacology and Experimental Therapeutics July 2008, 326 (1) 306-314; DOI: https://doi.org/10.1124/jpet.108.139204