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Research ArticleCARDIOVASCULAR

The Guinea Pig as a Preclinical Model for Demonstrating the Efficacy and Safety of Statins

Cort S. Madsen, Evan Janovitz, Rongan Zhang, Van Nguyen-Tran, Carol S. Ryan, Xiaohong Yin, Hossain Monshizadegan, Ming Chang, Celia D'Arienzo, Susan Scheer, Robert Setters, Debra Search, Xing Chen, Shaobin Zhuang, Lori Kunselman, Andrew Peters, Thomas Harrity, Atsu Apedo, Christine Huang, Carolyn A. Cuff, Mark C. Kowala, Michael A. Blanar, Chong-qing Sun, Jeffrey A. Robl and Philip D. Stein
Journal of Pharmacology and Experimental Therapeutics February 2008, 324 (2) 576-586; DOI: https://doi.org/10.1124/jpet.107.131615
Cort S. Madsen
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Evan Janovitz
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Rongan Zhang
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Van Nguyen-Tran
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Carol S. Ryan
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Xiaohong Yin
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Hossain Monshizadegan
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Ming Chang
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Celia D'Arienzo
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Susan Scheer
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Robert Setters
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Debra Search
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Xing Chen
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Shaobin Zhuang
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Lori Kunselman
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Andrew Peters
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Thomas Harrity
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Atsu Apedo
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Christine Huang
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Carolyn A. Cuff
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Mark C. Kowala
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Michael A. Blanar
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Chong-qing Sun
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Jeffrey A. Robl
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Philip D. Stein
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Article Information

vol. 324 no. 2 576-586
DOI 
https://doi.org/10.1124/jpet.107.131615
PubMed 
17986646

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received September 13, 2007
  • Accepted November 5, 2007
  • Published online January 24, 2008.

Article Versions

  • Earlier version (November 6, 2007 - 11:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Cort S. Madsen,
  2. Evan Janovitz,
  3. Rongan Zhang,
  4. Van Nguyen-Tran,
  5. Carol S. Ryan,
  6. Xiaohong Yin,
  7. Hossain Monshizadegan,
  8. Ming Chang,
  9. Celia D'Arienzo,
  10. Susan Scheer,
  11. Robert Setters,
  12. Debra Search,
  13. Xing Chen,
  14. Shaobin Zhuang,
  15. Lori Kunselman,
  16. Andrew Peters,
  17. Thomas Harrity,
  18. Atsu Apedo,
  19. Christine Huang,
  20. Carolyn A. Cuff,
  21. Mark C. Kowala,
  22. Michael A. Blanar,
  23. Chong-qing Sun,
  24. Jeffrey A. Robl and
  25. Philip D. Stein
  1. Bristol-Myers Squibb, Research and Development, Princeton, New Jersey (C.S.M., E.J., R.Z., C.S.R., X.Y., H.M., M.C., C.D., S.S., D.S., X.C., S.Z., L.K., A.P., T.H., A.A., C.H., M.A.B., C.-q.S., J.A.R., P.D.S.); Genomics Institute of the Novartis Research Foundation, La Jolla, California (V.N.-T.); Palatin Technologies Inc., Cranbury, New Jersey (R.S.); Abbott Laboratories, Worcester, Massachusetts (C.A.C.); Lilly Research Laboratories, Indiana (M.C.K.); and Redpoint Bio, Ewing, New Jersey (P.D.S.)
  1. Address correspondence to:
    Dr. Cort S. Madsen, Department of Atherosclerosis, Bristol-Myers Squibb Co., 311 Pennington-Rocky Hill Road, Pennington, NJ 08534. E-mail: cort.madsen{at}bms.com
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Journal of Pharmacology and Experimental Therapeutics: 387 (1)
Journal of Pharmacology and Experimental Therapeutics
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Research ArticleCARDIOVASCULAR

The Guinea Pig as a Preclinical Model for Demonstrating the Efficacy and Safety of Statins

Cort S. Madsen, Evan Janovitz, Rongan Zhang, Van Nguyen-Tran, Carol S. Ryan, Xiaohong Yin, Hossain Monshizadegan, Ming Chang, Celia D'Arienzo, Susan Scheer, Robert Setters, Debra Search, Xing Chen, Shaobin Zhuang, Lori Kunselman, Andrew Peters, Thomas Harrity, Atsu Apedo, Christine Huang, Carolyn A. Cuff, Mark C. Kowala, Michael A. Blanar, Chong-qing Sun, Jeffrey A. Robl and Philip D. Stein
Journal of Pharmacology and Experimental Therapeutics February 1, 2008, 324 (2) 576-586; DOI: https://doi.org/10.1124/jpet.107.131615

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Research ArticleCARDIOVASCULAR

The Guinea Pig as a Preclinical Model for Demonstrating the Efficacy and Safety of Statins

Cort S. Madsen, Evan Janovitz, Rongan Zhang, Van Nguyen-Tran, Carol S. Ryan, Xiaohong Yin, Hossain Monshizadegan, Ming Chang, Celia D'Arienzo, Susan Scheer, Robert Setters, Debra Search, Xing Chen, Shaobin Zhuang, Lori Kunselman, Andrew Peters, Thomas Harrity, Atsu Apedo, Christine Huang, Carolyn A. Cuff, Mark C. Kowala, Michael A. Blanar, Chong-qing Sun, Jeffrey A. Robl and Philip D. Stein
Journal of Pharmacology and Experimental Therapeutics February 1, 2008, 324 (2) 576-586; DOI: https://doi.org/10.1124/jpet.107.131615
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