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Research ArticleCELLULAR AND MOLECULAR

Neurokinin 1 Receptor Antagonists: Correlation between in Vitro Receptor Interaction and in Vivo Efficacy

Erik Lindström, Bengt von Mentzer, Ingrid Påhlman, Ingela Ahlstedt, Anna Uvebrant, Elin Kristensson, Rakel Martinsson, Anna Novén, Jennie de Verdier and Georges Vauquelin
Journal of Pharmacology and Experimental Therapeutics September 2007, 322 (3) 1286-1293; DOI: https://doi.org/10.1124/jpet.107.124958

Article Information

vol. 322 no. 3 1286-1293
DOI 
https://doi.org/10.1124/jpet.107.124958
PubMed 
17575073
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 27, 2007
  • Accepted June 14, 2007
  • Published online August 20, 2007.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Erik Lindström,
  2. Bengt von Mentzer,
  3. Ingrid Påhlman,
  4. Ingela Ahlstedt,
  5. Anna Uvebrant,
  6. Elin Kristensson,
  7. Rakel Martinsson,
  8. Anna Novén,
  9. Jennie de Verdier and
  10. Georges Vauquelin
  1. AstraZeneca R&D, Mölndal, Sweden (E.L., B.v.M., I.P., I.A., A.U., E.K., R.M., A.N., J.d.V.); and Department of Molecular and Biochemical Pharmacology, Vrije Universiteit Brussel, Brussels, Belgium (G.V.)
  1. Address correspondence to:
    Dr. Bengt von Mentzer, Astra Zeneca, Molecular Pharmacology, Kärragatan 5, 431 83 Mölndal, Sweden. E-mail: bengt.mentzer{at}astrazeneca.com
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Research ArticleCELLULAR AND MOLECULAR

Neurokinin 1 Receptor Antagonists: Correlation between in Vitro Receptor Interaction and in Vivo Efficacy

Erik Lindström, Bengt von Mentzer, Ingrid Påhlman, Ingela Ahlstedt, Anna Uvebrant, Elin Kristensson, Rakel Martinsson, Anna Novén, Jennie de Verdier and Georges Vauquelin
Journal of Pharmacology and Experimental Therapeutics September 1, 2007, 322 (3) 1286-1293; DOI: https://doi.org/10.1124/jpet.107.124958
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