A Novel, Orally Active CXCR1/2 Receptor Antagonist, Sch527123, Inhibits Neutrophil Recruitment, Mucus Production, and Goblet Cell Hyperplasia in Animal Models of Pulmonary Inflammation

Departments of Pulmonary and Peripheral Neurobiology (R.W.C., M.M., C.S.C., J.E.P., T.T.K., M.M.B. J.A.H.), Inflammation (R.W.H., X.F., G.D., W.G., J.S.F.), Drug Metabolism and Pharmacokinetics (D.R.), and Tumor Biology (R.B.), Discovery Research, Schering-Plough Research Institute, Kenilworth, New Jersey

Address correspondence to:
Dr. Richard W. Chapman, Schering Plough Research Institute, Pulmonary and Peripheral Neurobiology, 2015 Galloping Hill Rd, K-15-1650, Kenilworth, NJ 07033. E-mail: richard.chapman{at}spcorp.com

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