Journal of Pharmacology and Experimental Therapeutics: 322 (2)

August 01, 2007; Volume 322,Issue 2

PERSPECTIVES IN PHARMACOLOGY

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Building Individualized Medicine: Prevention of Adverse Reactions to Warfarin Therapy
Evgeny Krynetskiy and Patrick McDonnell

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 427-434; DOI: https://doi.org/10.1124/jpet.106.117952

BEHAVIORAL PHARMACOLOGY

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Relative Abuse Liability of Indiplon and Triazolam in Humans: A Comparison of Psychomotor, Subjective, and Cognitive Effects
Lawrence P. Carter, Roland R. Griffiths, Patricia E. Suess, John H. Casada, Christopher L. Wallace and John D. Roache

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 749-759; DOI: https://doi.org/10.1124/jpet.107.119693
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Noradrenergic Mechanisms in Cocaine-Induced Reinstatement of Drug Seeking in Squirrel Monkeys
Donna M. Platt, James K. Rowlett and Roger D. Spealman

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 894-902; DOI: https://doi.org/10.1124/jpet.107.121806

CARDIOVASCULAR

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Human Pharmacology of Naproxen Sodium
Marta L. Capone, Stefania Tacconelli, Maria G. Sciulli, Paola Anzellotti, Luigia Di Francesco, Gabriele Merciaro, Patrizia Di Gregorio and Paola Patrignani

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 453-460; DOI: https://doi.org/10.1124/jpet.107.122283
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Long-Term Treatment with the Apolipoprotein A1 Mimetic Peptide Increases Antioxidants and Vascular Repair in Type I Diabetic Rats
Stephen J. Peterson, Daniel Husney, Adam L. Kruger, Rafal Olszanecki, Francesca Ricci, Luigi F. Rodella, Alessandra Stacchiotti, Rita Rezzani, John A. McClung, Wilbert S. Aronow, Susumu Ikehara and Nader G. Abraham

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 514-520; DOI: https://doi.org/10.1124/jpet.107.119479
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Distinct Ca²⁺ Requirement for NO Production between Proteinase-Activated Receptor 1 and 4 (PAR₁ and PAR₄) in Vascular Endothelial Cells
Katsuya Hirano, Namie Nomoto, Mayumi Hirano, Fumi Momota, Akiko Hanada and Hideo Kanaide

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 668-677; DOI: https://doi.org/10.1124/jpet.107.121038
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Determination of Adenosine Effects and Adenosine Receptors in Murine Corpus Cavernosum
Rita C. Tostes, Fernanda R. C. Giachini, Fernando S. Carneiro, Romulo Leite, Edward W. Inscho and R. Clinton Webb

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 678-685; DOI: https://doi.org/10.1124/jpet.107.122705
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Regulation of Protease-Activated Receptor (PAR) 1 and PAR4 Signaling in Human Platelets by Compartmentalized Cyclic Nucleotide Actions
Matthew L. Bilodeau and Heidi E. Hamm

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 778-788; DOI: https://doi.org/10.1124/jpet.107.121830
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Do the Cardiovascular Effects of Angiotensin-Converting Enzyme (ACE) I Involve ACE-Independent Mechanisms? New Insights from Proline-Rich Peptides of Bothrops jararaca
Danielle Ianzer, Robson Augusto Souza Santos, Gisele Maia Etelvino, Carlos Henrique Xavier, Jerusa de Almeida Santos, Elizabeth Pereira Mendes, Leonor Tapias Machado, Benedito Carlos Prezoto, Vincent Dive and Antônio Carlos Martins de Camargo

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 795-805; DOI: https://doi.org/10.1124/jpet.107.120873
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Reciprocal Regulation of Endothelial Nitric-Oxide Synthase and NADPH Oxidase by Betulinic Acid in Human Endothelial Cells
Katja Steinkamp-Fenske, Larissa Bollinger, Hui Xu, Ying Yao, Sven Horke, Ulrich Förstermann and Huige Li

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 836-842; DOI: https://doi.org/10.1124/jpet.107.123356

CELLULAR AND MOLECULAR

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PDE4B5, a Novel, Super-Short, Brain-Specific cAMP Phosphodiesterase-4 Variant Whose Isoform-Specifying N-Terminal Region Is Identical to That of cAMP Phosphodiesterase-4D6 (PDE4D6)
York-Fong Cheung, Zhengyan Kan, Philip Garrett-Engele, Irene Gall, Hannah Murdoch, George S. Baillie, Luiz Miguel Camargo, Jason M. Johnson, Miles D. Houslay and John C. Castle

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 600-609; DOI: https://doi.org/10.1124/jpet.107.122218
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Competitive and Cooperative Effects of Bay K8644 on the L-Type Calcium Channel Current Inhibition by Calcium Channel Antagonists
Alexandra Zahradníková, Igor Minarovič and Ivan Zahradník

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 638-645; DOI: https://doi.org/10.1124/jpet.107.122176
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An Inhibitor of Casein Kinase Iϵ Induces Phase Delays in Circadian Rhythms under Free-Running and Entrained Conditions
Lori Badura, Terri Swanson, Wendy Adamowicz, Jessica Adams, Julie Cianfrogna, Katherine Fisher, Janice Holland, Robin Kleiman, Frederick Nelson, Linda Reynolds, Kristin St. Germain, Eric Schaeffer, Barbara Tate and Jeffrey Sprouse

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 730-738; DOI: https://doi.org/10.1124/jpet.107.122846

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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A Cannabinoid Anticancer Quinone, HU-331, Is More Potent and Less Cardiotoxic Than Doxorubicin: A Comparative in Vivo Study
Natalya M. Kogan, Michael Schlesinger, Maximilian Peters, Gergana Marincheva, Ronen Beeri and Raphael Mechoulam

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 646-653; DOI: https://doi.org/10.1124/jpet.107.120865

ENDOCRINE AND DIABETES

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Testing the Bipartite Model of the Sulfonylurea Receptor Binding Site: Binding of A-, B-, and A + B-Site Ligands
Marcus Winkler, Damian Stephan, Susanne Bieger, Petra Kühner, Felix Wolff and Ulrich Quast

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 701-708; DOI: https://doi.org/10.1124/jpet.107.123224
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Iptakalim, a Vascular ATP-Sensitive Potassium (K_ATP) Channel Opener, Closes Rat Pancreatic β-Cell K_ATP Channels and Increases Insulin Release
Naoko Misaki, Xia Mao, Yu-Fung Lin, Sechiko Suga, Guo-Hui Li, Qiang Liu, Yongchang Chang, Hai Wang, Makoto Wakui and Jie Wu

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 871-878; DOI: https://doi.org/10.1124/jpet.107.121129

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Inhibition of Adenosine Deaminase Attenuates Inflammation in Experimental Colitis
Luca Antonioli, Matteo Fornai, Rocchina Colucci, Narcisa Ghisu, Federico Da Settimo, Gianfranco Natale, Olga Kastsiuchenka, Emiliano Duranti, Agostino Virdis, Cristina Vassalle, Concettina La Motta, Laura Mugnaini, Maria Cristina Breschi, Corrado Blandizzi and Mario Del Taca

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 435-442; DOI: https://doi.org/10.1124/jpet.107.122762
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Ciglitazone, a Peroxisome Proliferator-Activated Receptor γ Inducer, Ameliorates Renal Preglomerular Production and Activity of Angiotensin II and Thromboxane A₂ in Glycerol-Induced Acute Renal Failure
Zivar Yousefipour, Hantz Hercule, Luan Truong, Adebayo Oyekan and Mohammad Newaz

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 461-468; DOI: https://doi.org/10.1124/jpet.107.122473
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Functional Characterization of Human Proton-Coupled Folate Transporter/Heme Carrier Protein 1 Heterologously Expressed in Mammalian Cells as a Folate Transporter
Yasuhiro Nakai, Katsuhisa Inoue, Naoki Abe, Mai Hatakeyama, Kin-ya Ohta, Masaki Otagiri, Yayoi Hayashi and Hiroaki Yuasa

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 469-476; DOI: https://doi.org/10.1124/jpet.107.122606
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Prostaglandin E₂ Enhances Acetylcholine-Induced, Ca²⁺-Dependent Ionic Currents in Swine Tracheal Mucous Gland Cells
Huiling Liu and Jerry M. Farley

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 501-513; DOI: https://doi.org/10.1124/jpet.107.120154
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Cyclic Arg-Gly-Asp Peptide-Labeled Liposomes for Targeting Drug Therapy of Hepatic Fibrosis in Rats
Shi-Lin Du, Hong Pan, Wei-Yue Lu, Jian Wang, Jian Wu and Ji-Yao Wang

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 560-568; DOI: https://doi.org/10.1124/jpet.107.122481
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Glucuronidation Converting Methyl 1-(3,4-Dimethoxyphenyl)-3-(3-ethylvaleryl)-4-hydroxy-6,7,8-trimethoxy-2-naphthoate (S-8921) to a Potent Apical Sodium-Dependent Bile Acid Transporter Inhibitor, Resulting in a Hypocholesterolemic Action
Shingo Sakamoto, Hiroyuki Kusuhara, Kenji Miyata, Hiroyuki Shimaoka, Takushi Kanazu, Yumiko Matsuo, Kohji Nomura, Noboru Okamura, Seijiro Hara, Kazutoshi Horie, Takahiko Baba and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 610-618; DOI: https://doi.org/10.1124/jpet.106.116426
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Neuronally Released Acetylcholine Acts on the M₂ Muscarinic Receptor to Oppose the Relaxant Effect of Isoproterenol on Cholinergic Contractions in Mouse Urinary Bladder
Frederick J. Ehlert, Simon Ahn, Kirk J. Pak, Grace J. Park, Marline S. Sangnil, John A. Tran and Minoru Matsui

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 631-637; DOI: https://doi.org/10.1124/jpet.107.121756

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA

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Pharmacological Characterization of Sch527123, a Potent Allosteric CXCR1/CXCR2 Antagonist
Waldemar Gonsiorek, Xuedong Fan, David Hesk, James Fossetta, Hongchen Qiu, James Jakway, Motasim Billah, Michael Dwyer, Jianhua Chao, Gregory Deno, Art Taveras, Daniel J. Lundell and R. William Hipkin

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 477-485; DOI: https://doi.org/10.1124/jpet.106.118927
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A Novel, Orally Active CXCR1/2 Receptor Antagonist, Sch527123, Inhibits Neutrophil Recruitment, Mucus Production, and Goblet Cell Hyperplasia in Animal Models of Pulmonary Inflammation
Richard W. Chapman, Michael Minnicozzi, Chander S. Celly, Jonathan E. Phillips, Ted T. Kung, R. William Hipkin, Xuedong Fan, Diane Rindgen, Gregory Deno, Richard Bond, Waldemar Gonsiorek, Motasim M. Billah, Jay S. Fine and John A. Hey

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 486-493; DOI: https://doi.org/10.1124/jpet.106.119040
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Antigen-Specific Suppression of Experimental Autoimmune Encephalomyelitis by a Novel Bifunctional Peptide Inhibitor
Naoki Kobayashi, Hitomi Kobayashi, Leo Gu, Thomas Malefyt and Teruna J. Siahaan

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 879-886; DOI: https://doi.org/10.1124/jpet.107.123257
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Antiarthritic Effects of Relaxin, in Combination with Estrogen, in Rat Adjuvant-Induced Arthritis
Karen Santora, Cordelia Rasa, Denise Visco, Bernard G. Steinetz and Carol A. Bagnell

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 887-893; DOI: https://doi.org/10.1124/jpet.107.122903

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

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Human Hydroxysteroid Sulfotransferase SULT2B1 Pharmacogenomics: Gene Sequence Variation and Functional Genomics
Yuan Ji, Irene Moon, Jelena Zlatkovic, Oreste E. Salavaggione, Bianca A. Thomae, Bruce W. Eckloff, Eric D. Wieben, Daniel J. Schaid and Richard M. Weinshilboum

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 529-540; DOI: https://doi.org/10.1124/jpet.107.122895
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Transport of Paraquat by Human Organic Cation Transporters and Multidrug and Toxic Compound Extrusion Family
Ying Chen, Shuzhong Zhang, Marco Sorani and Kathleen M. Giacomini

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 695-700; DOI: https://doi.org/10.1124/jpet.107.123554
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Flavonoid Glycosides Are Not Transported by the Human Na⁺/Glucose Transporter When Expressed in Xenopus laevis Oocytes, but Effectively Inhibit Electrogenic Glucose Uptake
Gabor Kottra and Hannelore Daniel

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 829-835; DOI: https://doi.org/10.1124/jpet.107.124040
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Dehydrogenation of Indoline by Cytochrome P450 Enzymes: A Novel “Aromatase” Process
Hao Sun, William J. Ehlhardt, Palaniappan Kulanthaivel, Diane L. Lanza, Christopher A. Reilly and Garold S. Yost

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 843-851; DOI: https://doi.org/10.1124/jpet.107.121723

NEUROPHARMACOLOGY

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Activation of a Novel Injury-Induced Calcium-Permeable Channel That Plays a Key Role in Causing Extended Neuronal Depolarization and Initiating Neuronal Death in Excitotoxic Neuronal Injury
Laxmikant S. Deshpande, David D. Limbrick, Sompong Sombati and Robert J. DeLorenzo

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 443-452; DOI: https://doi.org/10.1124/jpet.107.123182
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Effects of Lamotrigine Alone and in Combination with MK-801, Phenobarbital, or Phenytoin on Cell Death in the Neonatal Rat Brain
Irina Katz, Jinsook Kim, Karen Gale and Alexei Kondratyev

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 494-500; DOI: https://doi.org/10.1124/jpet.107.123133
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The Effect of Recombinant Human Erythropoietin on Neurovasculature Repair after Focal Ischemic Stroke in Neonatal Rats
Christine L. Keogh, Shan Ping Yu and Ling Wei

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 521-528; DOI: https://doi.org/10.1124/jpet.107.121392
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Pharmacokinetics and Amyloid Plaque Targeting Ability of a Novel Peptide-Based Magnetic Resonance Contrast Agent in Wild-Type and Alzheimer's Disease Transgenic Mice
Karunya K. Kandimalla, Thomas M. Wengenack, Geoffry L. Curran, Emily J. Gilles and Joseph F. Poduslo

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 541-549; DOI: https://doi.org/10.1124/jpet.107.119883
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Antiepileptic Drugs Affect Neuronal Androgen Signaling via a Cytochrome P450-Dependent Pathway
Marcel Gehlhaus, Nina Schmitt, Benedikt Volk and Ralf P. Meyer

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 550-559; DOI: https://doi.org/10.1124/jpet.107.120303
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Benzodiazepine Withdrawal-Induced Glutamatergic Plasticity Involves Up-Regulation of GluR1-Containing α-Amino-3-hydroxy-5-methylisoxazole-4-propionic Acid Receptors in Hippocampal CA1 Neurons
Jun Song, Guofu Shen, L. John Greenfield and Elizabeth I. Tietz

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 569-581; DOI: https://doi.org/10.1124/jpet.107.121798
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Atrial Natriuretic Peptide Reduces Ischemia/Reperfusion-Induced Spinal Cord Injury in Rats by Enhancing Sensory Neuron Activation
Takuya Nakayama, Naoaki Harada, Miki Asano, Norikazu Nomura, Takayuki Saito, Akira Mishima and Kenji Okajima

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 582-590; DOI: https://doi.org/10.1124/jpet.107.120725
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Galantamine Postischemia Provides Neuroprotection and Memory Recovery against Transient Global Cerebral Ischemia in Gerbils
Silvia Lorrio, Mónica Sobrado, Esperanza Arias, José M. Roda, Antonio G. García and Manuela G. López

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 591-599; DOI: https://doi.org/10.1124/jpet.107.122747
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Pharmacological, Pharmacokinetic, and Primate Analgesic Efficacy Profile of the Novel Bradykinin B₁ Receptor Antagonist ELN441958
Jon E. Hawkinson, Balazs G. Szoke, Albert W. Garofalo, Dennis S. Hom, Hongbing Zhang, Mark Dreyer, Juri Y. Fukuda, Linda Chen, Bhushan Samant, Stellanie Simmonds, Karla P. Zeitz, Angie Wadsworth, Anna Liao, Raymond A. Chavez, Wes Zmolek, Lany Ruslim, Michael P. Bova, Ryan Holcomb, Eduardo R. Butelman, Mei-Chuan Ko and Annika B. Malmberg

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 619-630; DOI: https://doi.org/10.1124/jpet.107.120352
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Sexually Dimorphic Recruitment of Spinal Opioid Analgesic Pathways by the Spinal Application of Morphine
Nai-Jiang Liu, Hans von Gizycki and Alan R. Gintzler

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 654-660; DOI: https://doi.org/10.1124/jpet.107.123620
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Low Sensitivity of the Positron Emission Tomography Ligand [¹¹C]Diprenorphine to Agonist Opiates
Susan P. Hume, Anne R. Lingford-Hughes, Valerie Nataf, Ella Hirani, Rabia Ahmad, Andrew N. Davies and David J. Nutt

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 661-667; DOI: https://doi.org/10.1124/jpet.107.121749
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CJ-023,423, a Novel, Potent and Selective Prostaglandin EP₄ Receptor Antagonist with Antihyperalgesic Properties
Kazunari Nakao, Akio Murase, Hiroyuki Ohshiro, Takako Okumura, Kana Taniguchi, Yoko Murata, Masatoshi Masuda, Tomoki Kato, Yoshiyuki Okumura and Junji Takada

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 686-694; DOI: https://doi.org/10.1124/jpet.107.122010
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Identification and Characterization of Cholest-4-en-3-one, Oxime (TRO19622), a Novel Drug Candidate for Amyotrophic Lateral Sclerosis
Thierry Bordet, Bruno Buisson, Magali Michaud, Cyrille Drouot, Pascale Galéa, Pierre Delaage, Natalia P. Akentieva, Alex S. Evers, Douglas F. Covey, Mariano A. Ostuni, Jean-Jacques Lacapère, Charbel Massaad, Michael Schumacher, Esther-Marie Steidl, Delphine Maux, Michel Delaage, Christopher E. Henderson and Rebecca M. Pruss

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 709-720; DOI: https://doi.org/10.1124/jpet.107.123000
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Memantine Inhibits ATP-Dependent K⁺ Conductances in Dopamine Neurons of the Rat Substantia Nigra Pars Compacta
Michela Giustizieri, Maria Letizia Cucchiaroni, Ezia Guatteo, Giorgio Bernardi, Nicola B. Mercuri and Nicola Berretta

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 721-729; DOI: https://doi.org/10.1124/jpet.107.122036
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Applicability of the Dopamine and Rate Hypotheses in Explaining the Differences in Behavioral Pharmacology of the Chloro-Benztropine Analogs: Studies Conducted Using Intracerebral Microdialysis and Population Pharmacodynamic Modeling
Ahmed A. Othman, Amy Hauck Newman and Natalie D. Eddington

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 760-769; DOI: https://doi.org/10.1124/jpet.107.123315
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Impaired Microsomal Oxidation of the Atypical Antipsychotic Agent Clozapine in Hepatic Steatosis
Wei V. Zhang, Iqbal Ramzan and Michael Murray

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 770-777; DOI: https://doi.org/10.1124/jpet.107.124024
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Tumor Necrosis Factor (TNF)-Soluble High-Affinity Receptor Complex as a TNF Antagonist
Sean D. McKenna, Georg Feger, Christie Kelton, Meijia Yang, Vittoria Ardissone, Rocco Cirillo, Pierre-Alain Vitte, Xuliang Jiang and Robert K. Campbell

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 822-828; DOI: https://doi.org/10.1124/jpet.107.119875
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ACP-103, a 5-Hydroxytryptamine 2A Receptor Inverse Agonist, Improves the Antipsychotic Efficacy and Side-Effect Profile of Haloperidol and Risperidone in Experimental Models
Luis R. Gardell, Kimberly E. Vanover, Linda Pounds, Robert W. Johnson, Richard Barido, Gary T. Anderson, Isaac Veinbergs, Agnete Dyssegaard, Per Brunmark, Ali Tabatabaei, Robert E. Davis, Mark R. Brann, Uli Hacksell and Douglas W. Bonhaus

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 862-870; DOI: https://doi.org/10.1124/jpet.107.121715

TOXICOLOGY

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Pharmacological Characterization of Glycine-Activated Currents in HEK 293 Cells Expressing N-Methyl-D-aspartate NR1 and NR3 Subunits
C. Thetford Smothers and John J. Woodward

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 739-748; DOI: https://doi.org/10.1124/jpet.107.123836
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Neuroprotection with Erythropoietin Administration Following Controlled Cortical Impact Injury in Rats
Leela Cherian, J. Clay Goodman and Claudia Robertson

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 789-794; DOI: https://doi.org/10.1124/jpet.107.119628
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Sensitization and Activation of Intracranial Meningeal Nociceptors by Mast Cell Mediators
Xi-Chun Zhang, Andrew M. Strassman, Rami Burstein and Dan Levy

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 806-812; DOI: https://doi.org/10.1124/jpet.107.123745
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Mechanisms Responsible for the Enhanced Antinociceptive Effects of μ-Opioid Receptor Agonists in the Rostral Ventromedial Medulla of Male Rats with Persistent Inflammatory Pain
Kenneth T. Sykes, Stephanie R. White, Robert W. Hurley, Hirokazu Mizoguchi, Leon F. Tseng and Donna L. Hammond

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 813-821; DOI: https://doi.org/10.1124/jpet.107.121954
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Neutrophil Interaction with the Hemostatic System Contributes to Liver Injury in Rats Cotreated with Lipopolysaccharide and Ranitidine
Xiaomin Deng, James P. Luyendyk, Wei Zou, Jingtao Lu, Ernst Malle, Patricia E. Ganey and Robert A. Roth

Journal of Pharmacology and Experimental Therapeutics August 2007, 322 (2) 852-861; DOI: https://doi.org/10.1124/jpet.107.122069

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND DIABETES

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION, IMMUNOPHARMACOLOGY, AND ASTHMA

METABOLISM, TRANSPORT, AND PHARMACOGENOMICS

NEUROPHARMACOLOGY

TOXICOLOGY

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