Histone Deacetylase Inhibitors Exhibit Anti-Inflammatory and Neuroprotective Effects in a Rat Permanent Ischemic Model of Stroke: Multiple Mechanisms of Action

Molecular Neurobiology Section, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland (H.J.K., M.Ro., M.Re., D.-M.C.); and Neuropharmacology Section, Laboratory of Pharmacology and Chemistry, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (J.-S.H., P.-S.C.)

Address correspondence to:
Dr. De-Maw Chuang, Molecular Neurobiology Section, National Institute of Mental Health, National Institutes of Health, Building 10, Room 4C-206, 10 Center Drive, MSC-1363, Bethesda, MD 20892-1363. E-mail: chuang{at}mail.nih.gov

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: March 2007 to March 2023

	Abstract	Full	Pdf
Mar 2007	40	0	263
Apr 2007	24	0	291
May 2007	86	64	225
Jun 2007	51	95	115
Jul 2007	241	118	241
Aug 2007	65	88	107
Sep 2007	27	61	75
Oct 2007	41	67	94
Nov 2007	27	45	57
Dec 2007	24	51	39
Jan 2008	35	67	70
Feb 2008	34	58	86
Mar 2008	29	41	47
Apr 2008	38	43	61
May 2008	46	40	50
Jun 2008	26	103	106
Jul 2008	35	113	112
Aug 2008	47	75	54
Sep 2008	45	64	56
Oct 2008	26	83	71
Nov 2008	31	52	69
Dec 2008	14	58	50
Jan 2009	11	67	69
Feb 2009	9	58	50
Mar 2009	30	98	79
Apr 2009	31	72	55
May 2009	18	61	58
Jun 2009	17	58	68
Jul 2009	30	77	78
Aug 2009	31	55	55
Sep 2009	47	54	75
Oct 2009	50	71	70
Nov 2009	24	37	45
Dec 2009	21	29	40
Jan 2010	37	41	46
Feb 2010	45	54	53
Mar 2010	43	64	60
Apr 2010	32	59	44
May 2010	58	63	59
Jun 2010	66	52	62
Jul 2010	51	60	54
Aug 2010	62	56	50
Sep 2010	57	60	77
Oct 2010	41	80	55
Nov 2010	37	53	51
Dec 2010	38	55	39
Jan 2011	31	50	41
Feb 2011	33	38	36
Mar 2011	40	69	58
Apr 2011	30	43	47
May 2011	33	73	66
Jun 2011	23	43	38
Jul 2011	38	51	46
Aug 2011	27	53	34
Sep 2011	28	54	50
Oct 2011	40	63	49
Nov 2011	42	72	49
Dec 2011	36	75	53
Jan 2012	25	81	54
Feb 2012	39	132	79
Mar 2012	45	77	48
Apr 2012	42	92	81
May 2012	42	67	49
Jun 2012	31	66	63
Jul 2012	32	80	65
Aug 2012	35	61	38
Sep 2012	33	60	42
Oct 2012	55	50	40
Nov 2012	46	47	40
Dec 2012	56	46	52
Jan 2013	27	67	276
Feb 2013	42	55	150
Mar 2013	50	56	71
Apr 2013	55	67	52
May 2013	34	61	37
Jun 2013	37	34	24
Jul 2013	21	28	44
Aug 2013	16	41	29
Sep 2013	34	36	25
Oct 2013	31	42	35
Nov 2013	28	34	23
Dec 2013	19	32	19
Jan 2014	47	76	46
Feb 2014	28	55	39
Mar 2014	55	59	43
Apr 2014	44	63	44
May 2014	37	47	40
Jun 2014	32	27	20
Jul 2014	65	51	43
Aug 2014	40	49	30
Sep 2014	23	38	31
Oct 2014	27	39	39
Nov 2014	42	60	32
Dec 2014	29	30	26
Jan 2015	109	44	42
Feb 2015	25	24	34
Mar 2015	47	56	39
Apr 2015	25	47	26
May 2015	31	42	31
Jun 2015	20	37	27
Jul 2015	23	51	46
Aug 2015	26	41	19
Sep 2015	43	50	30
Oct 2015	27	54	37
Nov 2015	37	57	24
Dec 2015	32	40	27
Jan 2016	68	51	49
Feb 2016	46	37	24
Mar 2016	28	28	26
Apr 2016	44	53	21
May 2016	26	37	18
Jun 2016	34	35	45
Jul 2016	26	31	30
Aug 2016	33	28	27
Sep 2016	27	47	37
Oct 2016	40	30	18
Nov 2016	33	34	23
Dec 2016	13	68	25
Jan 2017	12	70	13
Feb 2017	14	48	31
Mar 2017	13	50	28
Apr 2017	23	39	23
May 2017	9	51	20
Jun 2017	12	48	24
Jul 2017	10	56	29
Aug 2017	11	56	25
Sep 2017	22	55	31
Oct 2017	12	64	34
Nov 2017	17	55	31
Dec 2017	10	46	15
Jan 2018	12	61	22
Feb 2018	13	66	20
Mar 2018	11	63	20
Apr 2018	6	86	43
May 2018	7	60	42
Jun 2018	5	43	29
Jul 2018	6	50	21
Aug 2018	9	47	15
Sep 2018	5	46	22
Oct 2018	8	59	28
Nov 2018	5	51	28
Dec 2018	54	13	18
Jan 2019	47	14	4
Feb 2019	64	18	8
Mar 2019	55	9	20
Apr 2019	41	9	15
May 2019	31	6	8
Jun 2019	54	11	12
Jul 2019	37	11	13
Aug 2019	84	7	10
Sep 2019	61	12	11
Oct 2019	35	19	10
Nov 2019	53	11	6
Dec 2019	38	18	7
Jan 2020	69	18	9
Feb 2020	70	6	5
Mar 2020	55	10	5
Apr 2020	56	7	4
May 2020	96	6	4
Jun 2020	47	7	6
Jul 2020	23	6	2
Aug 2020	32	15	8
Sep 2020	42	2	3
Oct 2020	47	7	4
Nov 2020	52	6	3
Dec 2020	49	11	11
Jan 2021	52	11	12
Feb 2021	41	5	8
Mar 2021	63	9	6
Apr 2021	38	4	9
May 2021	61	7	8
Jun 2021	52	8	9
Jul 2021	66	2	7
Aug 2021	56	8	7
Sep 2021	38	8	7
Oct 2021	48	9	5
Nov 2021	41	5	6
Dec 2021	54	9	5
Jan 2022	53	7	14
Feb 2022	68	7	11
Mar 2022	66	7	9
Apr 2022	99	3	10
May 2022	71	7	9
Jun 2022	33	5	5
Jul 2022	42	9	8
Aug 2022	64	9	6
Sep 2022	76	5	8
Oct 2022	64	7	7
Nov 2022	121	5	6
Dec 2022	83	4	6
Jan 2023	80	10	6
Feb 2023	44	7	8
Mar 2023	83	4	5