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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Binding of Inhibitory Fatty Acids Is Responsible for the Enhancement of UDP-Glucuronosyltransferase 2B7 Activity by Albumin: Implications for in Vitro-in Vivo Extrapolation

Andrew Rowland, Paraskevi Gaganis, David J. Elliot, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
Journal of Pharmacology and Experimental Therapeutics April 2007, 321 (1) 137-147; DOI: https://doi.org/10.1124/jpet.106.118216

Article Information

vol. 321 no. 1 137-147
DOI 
https://doi.org/10.1124/jpet.106.118216
PubMed 
17237258
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received December 5, 2006
  • Accepted January 16, 2007
  • Published online March 18, 2007.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Andrew Rowland,
  2. Paraskevi Gaganis,
  3. David J. Elliot,
  4. Peter I. Mackenzie,
  5. Kathleen M. Knights and
  6. John O. Miners
  1. Department of Clinical Pharmacology, Flinders University and Flinders Medical Centre, Adelaide, Australia
  1. Address correspondence to:
    Dr. John Miners, Department of Clinical Pharmacology, Flinders Medical Centre, Bedford Park, SA 5042, Australia. E-mail: john.miners{at}flinders.edu.au
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Binding of Inhibitory Fatty Acids Is Responsible for the Enhancement of UDP-Glucuronosyltransferase 2B7 Activity by Albumin: Implications for in Vitro-in Vivo Extrapolation

Andrew Rowland, Paraskevi Gaganis, David J. Elliot, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
Journal of Pharmacology and Experimental Therapeutics April 1, 2007, 321 (1) 137-147; DOI: https://doi.org/10.1124/jpet.106.118216
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