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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Stephanie R. Faucette, Tong-Cun Zhang, Rick Moore, Tatsuya Sueyoshi, Curtis J. Omiecinski, Edward L. LeCluyse, Masahiko Negishi and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics January 2007, 320 (1) 72-80; DOI: https://doi.org/10.1124/jpet.106.112136
Stephanie R. Faucette
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Tong-Cun Zhang
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Rick Moore
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Tatsuya Sueyoshi
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Curtis J. Omiecinski
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Edward L. LeCluyse
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Masahiko Negishi
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Hongbing Wang
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Article Information

vol. 320 no. 1 72-80
DOI 
https://doi.org/10.1124/jpet.106.112136
PubMed 
17041008

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 7, 2006
  • Accepted October 11, 2006
  • Published online December 20, 2006.

Article Versions

  • Earlier version (October 13, 2006 - 07:40).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Stephanie R. Faucette,
  2. Tong-Cun Zhang,
  3. Rick Moore,
  4. Tatsuya Sueyoshi,
  5. Curtis J. Omiecinski,
  6. Edward L. LeCluyse,
  7. Masahiko Negishi and
  8. Hongbing Wang
  1. Division of Molecular Pharmaceutics, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina (S.R.F., T.-C.Z.); Pharmacogenetics Section, Laboratory of Reproductive and Developmental Toxicology, National Institute of Environmental and Health Sciences, National Institutes of Health, Research Triangle Park, North Carolina (R.M., T.S., M.N.); Center for Molecular Toxicology and Carcinogenesis, Pennsylvania State University, University Park, Pennsylvania (C.J.O.); CellzDirect, Inc., Pittsboro, North Carolina (E.L.L.); and Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, Maryland (H.W.)
  1. Address correspondence to:
    Dr. Hongbing Wang, Department of Pharmaceutical Sciences, School of Pharmacy, University of Maryland, Baltimore, MD 21201-6808. E-mail: hwang{at}rx.umaryland.edu
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Journal of Pharmacology and Experimental Therapeutics: 381 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 381, Issue 2
1 May 2022
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Stephanie R. Faucette, Tong-Cun Zhang, Rick Moore, Tatsuya Sueyoshi, Curtis J. Omiecinski, Edward L. LeCluyse, Masahiko Negishi and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics January 1, 2007, 320 (1) 72-80; DOI: https://doi.org/10.1124/jpet.106.112136

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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Relative Activation of Human Pregnane X Receptor versus Constitutive Androstane Receptor Defines Distinct Classes of CYP2B6 and CYP3A4 Inducers

Stephanie R. Faucette, Tong-Cun Zhang, Rick Moore, Tatsuya Sueyoshi, Curtis J. Omiecinski, Edward L. LeCluyse, Masahiko Negishi and Hongbing Wang
Journal of Pharmacology and Experimental Therapeutics January 1, 2007, 320 (1) 72-80; DOI: https://doi.org/10.1124/jpet.106.112136
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