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Research ArticleNEUROPHARMACOLOGY

Modafinil Occupies Dopamine and Norepinephrine Transporters in Vivo and Modulates the Transporters and Trace Amine Activity in Vitro

Bertha K. Madras, Zhihua Xie, Zhicheng Lin, Amy Jassen, Helen Panas, Laurie Lynch, Ryan Johnson, Eli Livni, Thomas J. Spencer, Ali A. Bonab, Gregory M. Miller and Alan J. Fischman
Journal of Pharmacology and Experimental Therapeutics November 2006, 319 (2) 561-569; DOI: https://doi.org/10.1124/jpet.106.106583

Article Information

vol. 319 no. 2 561-569
DOI 
https://doi.org/10.1124/jpet.106.106583
PubMed 
16885432
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 21, 2006
  • Accepted July 26, 2006
  • Published online October 19, 2006.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Bertha K. Madras,
  2. Zhihua Xie,
  3. Zhicheng Lin,
  4. Amy Jassen,
  5. Helen Panas,
  6. Laurie Lynch,
  7. Ryan Johnson,
  8. Eli Livni,
  9. Thomas J. Spencer,
  10. Ali A. Bonab,
  11. Gregory M. Miller and
  12. Alan J. Fischman
  1. Department of Psychiatry, Harvard Medical School and New England Primate Research Center, Southborough, Massachusetts (B.K.M., Z.X., Z.L., A.J., H.P., L.L., R.J., G.M.M.); and Massachusetts General Hospital, Boston, Massachusetts (E.L., T.J.S., A.A.B., A.J.F.)
  1. Address correspondence to:
    Dr. Bertha K. Madras, Department of Psychiatry, Harvard Medical School, New England Primate Research Center, 1 Pine Hill Dr., Southborough, MA 01772-9102. E-mail: bertha_madras{at}hms.harvard.edu
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Research ArticleNEUROPHARMACOLOGY

Modafinil Occupies Dopamine and Norepinephrine Transporters in Vivo and Modulates the Transporters and Trace Amine Activity in Vitro

Bertha K. Madras, Zhihua Xie, Zhicheng Lin, Amy Jassen, Helen Panas, Laurie Lynch, Ryan Johnson, Eli Livni, Thomas J. Spencer, Ali A. Bonab, Gregory M. Miller and Alan J. Fischman
Journal of Pharmacology and Experimental Therapeutics November 1, 2006, 319 (2) 561-569; DOI: https://doi.org/10.1124/jpet.106.106583
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