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Concentration-Dependent Modulation of Amyloid-β in Vivo and in Vitro Using the γ-Secretase Inhibitor, LY-450139
Thomas A. Lanz, Michael J. Karmilowicz, Kathleen M. Wood, Nikolay Pozdnyakov, Ping Du, Mary A. Piotrowski, Tracy M. Brown, Charles E. Nolan, Karl E. G. Richter, James E. Finley, Qing Fei, Charles F. Ebbinghaus, Yuhpyng L. Chen, Douglas K. Spracklin, Barbara Tate, Kieran F. Geoghegan, Lit-Fui Lau, David D. Auperin and Joel B. Schachter
Journal of Pharmacology and Experimental Therapeutics November 2006, 319 (2) 924-933; DOI: https://doi.org/10.1124/jpet.106.110700