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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat

Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Joan E. Humphreys, Xianbin Tian, Ken-ichi Nezasa and Kim L. R. Brouwer
Journal of Pharmacology and Experimental Therapeutics October 2006, 319 (1) 459-467; DOI: https://doi.org/10.1124/jpet.106.101840

Article Information

vol. 319 no. 1 459-467
DOI 
https://doi.org/10.1124/jpet.106.101840
PubMed 
16857726
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received January 25, 2006
  • Accepted July 18, 2006
  • Published online September 25, 2006.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Maciej J. Zamek-Gliszczynski1,
  2. Keith A. Hoffmaster,
  3. Joan E. Humphreys,
  4. Xianbin Tian,
  5. Ken-ichi Nezasa2 and
  6. Kim L. R. Brouwer
  1. University of North Carolina, School of Pharmacy, Chapel Hill, North Carolina (M.J.Z.-G., X.T., K.N., K.L.R.B.); Pfizer Research Technology Center, Cambridge, Massachusetts (K.A.H.); and GlaxoSmithKline, Inc., Research Triangle Park, North Carolina (J.E.H.)
  1. Address correspondence to:
    Dr. Kim L. R. Brouwer, George H. Cocolas Distinguished Professor, University of North Carolina School of Pharmacy, Kerr Hall, CB#7360, Chapel Hill, NC 27599-7360. E-mail: kbrouwer{at}unc.edu
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Differential Involvement of Mrp2 (Abcc2) and Bcrp (Abcg2) in Biliary Excretion of 4-Methylumbelliferyl Glucuronide and Sulfate in the Rat

Maciej J. Zamek-Gliszczynski, Keith A. Hoffmaster, Joan E. Humphreys, Xianbin Tian, Ken-ichi Nezasa and Kim L. R. Brouwer
Journal of Pharmacology and Experimental Therapeutics October 1, 2006, 319 (1) 459-467; DOI: https://doi.org/10.1124/jpet.106.101840
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