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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Urinary Metabolite Profiling Reveals CYP1A2-Mediated Metabolism of NSC686288 (Aminoflavone)

Chi Chen, Linghua Meng, Xiaochao Ma, Kristopher W. Krausz, Yves Pommier, Jeffrey R. Idle and Frank J. Gonzalez
Journal of Pharmacology and Experimental Therapeutics September 2006, 318 (3) 1330-1342; DOI: https://doi.org/10.1124/jpet.106.105213
Chi Chen
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Linghua Meng
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Xiaochao Ma
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Kristopher W. Krausz
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Yves Pommier
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Jeffrey R. Idle
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Frank J. Gonzalez
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Article Information

vol. 318 no. 3 1330-1342
DOI 
https://doi.org/10.1124/jpet.106.105213
PubMed 
16775196

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received March 24, 2006
  • Accepted June 13, 2006
  • Published online August 18, 2006.

Article Versions

  • Earlier version (June 14, 2006 - 11:03).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Chi Chen,
  2. Linghua Meng,
  3. Xiaochao Ma,
  4. Kristopher W. Krausz,
  5. Yves Pommier,
  6. Jeffrey R. Idle and
  7. Frank J. Gonzalez
  1. Laboratories of Metabolism (C.C., X.M., K.W.K., F.J.G.) and Molecular Pharmacology (L.M., Y.P.), Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland; and Institute of Pharmacology, First Faculty of Medicine, Charles University, Prague, Czech Republic (J.R.I.)
  1. Address correspondence to:
    Dr. Frank J. Gonzalez, Laboratory of Metabolism, National Cancer Institute, 37 Convent Drive, Bethesda, MD 20892. E-mail: fjgonz{at}helix.nih.gov
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Journal of Pharmacology and Experimental Therapeutics: 376 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 376, Issue 2
1 Feb 2021
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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Urinary Metabolite Profiling Reveals CYP1A2-Mediated Metabolism of NSC686288 (Aminoflavone)

Chi Chen, Linghua Meng, Xiaochao Ma, Kristopher W. Krausz, Yves Pommier, Jeffrey R. Idle and Frank J. Gonzalez
Journal of Pharmacology and Experimental Therapeutics September 1, 2006, 318 (3) 1330-1342; DOI: https://doi.org/10.1124/jpet.106.105213

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Research ArticleMETABOLISM, TRANSPORT, AND PHARMACOGENOMICS

Urinary Metabolite Profiling Reveals CYP1A2-Mediated Metabolism of NSC686288 (Aminoflavone)

Chi Chen, Linghua Meng, Xiaochao Ma, Kristopher W. Krausz, Yves Pommier, Jeffrey R. Idle and Frank J. Gonzalez
Journal of Pharmacology and Experimental Therapeutics September 1, 2006, 318 (3) 1330-1342; DOI: https://doi.org/10.1124/jpet.106.105213
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