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Research ArticleNEUROPHARMACOLOGY

The δ Subunit of γ-Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol

Cecilia M. Borghese, Signe í Stórustovu, Bjarke Ebert, Murray B. Herd, Delia Belelli, Jeremy J. Lambert, George Marshall, Keith A. Wafford and R. Adron Harris
Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1360-1368; DOI: https://doi.org/10.1124/jpet.105.092452
Cecilia M. Borghese
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Signe í Stórustovu
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Bjarke Ebert
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Murray B. Herd
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Delia Belelli
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Jeremy J. Lambert
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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George Marshall
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Keith A. Wafford
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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R. Adron Harris
Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
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Article Information

vol. 316 no. 3 1360-1368
DOI 
https://doi.org/10.1124/jpet.105.092452
PubMed 
16272217

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 11, 2005
  • Accepted October 6, 2005
  • Published online February 21, 2006.

Article Versions

  • Earlier version (November 4, 2005 - 08:28).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Cecilia M. Borghese,
  2. Signe í Stórustovu,
  3. Bjarke Ebert,
  4. Murray B. Herd,
  5. Delia Belelli,
  6. Jeremy J. Lambert,
  7. George Marshall,
  8. Keith A. Wafford, and
  9. R. Adron Harris
  1. Waggoner Center for Alcohol and Addiction Research, The University of Texas at Austin, Austin, Texas (C.M.B., R.A.H.); Department of Electrophysiology, H. Lundbeck A/S, Valby, Denmark (S.S., B.E.); Neuroscience Institute, Division of Pathology and Neuroscience, Ninewells Hospital and Medical School, Dundee University, Dundee, United Kingdom (M.B.H., D.B., J.J.L.); and Department of Molecular and Cellular Neuroscience, Merck Sharp & Dohme Research Laboratories, The Neuroscience Research Centre, Harlow, United Kingdom (G.M., K.A.W.)
  1. Address correspondence to:
    Dr. R. Adron Harris, The University of Texas at Austin, Waggoner Center for Alcohol and Addiction Research, 1 University Station A4800, Austin, TX 78712-0159. E-mail: harris{at}mail.utexas.edu
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Journal of Pharmacology and Experimental Therapeutics: 316 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 316, Issue 3
1 Mar 2006
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Research ArticleNEUROPHARMACOLOGY

The δ Subunit of γ-Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol

Cecilia M. Borghese, Signe í Stórustovu, Bjarke Ebert, Murray B. Herd, Delia Belelli, Jeremy J. Lambert, George Marshall, Keith A. Wafford and R. Adron Harris
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1360-1368; DOI: https://doi.org/10.1124/jpet.105.092452

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Research ArticleNEUROPHARMACOLOGY

The δ Subunit of γ-Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol

Cecilia M. Borghese, Signe í Stórustovu, Bjarke Ebert, Murray B. Herd, Delia Belelli, Jeremy J. Lambert, George Marshall, Keith A. Wafford and R. Adron Harris
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1360-1368; DOI: https://doi.org/10.1124/jpet.105.092452
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