Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily
Stephan Steckelbroeck, Busola Oyesanmi, Yi Jin, Seon-Hwa Lee, Helenius J. Kloosterboer and Trevor M. Penning
Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1300-1309; DOI: https://doi.org/10.1124/jpet.105.091587
Stephan Steckelbroeck
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Busola Oyesanmi
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Yi Jin
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Seon-Hwa Lee
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Helenius J. Kloosterboer
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Trevor M. Penning
Department of Pharmacology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania (S.S., B.O., Y.J., S.-H.L., T.M.P.); and Research and Development Laboratories, NV Organon, Oss, The Netherlands (H.J.K.)
Submit a Response to This Article
Jump to comment:
No eLetters have been published for this article.
In this issue
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily
Stephan Steckelbroeck, Busola Oyesanmi, Yi Jin, Seon-Hwa Lee, Helenius J. Kloosterboer and Trevor M. Penning
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1300-1309; DOI: https://doi.org/10.1124/jpet.105.091587
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily
Stephan Steckelbroeck, Busola Oyesanmi, Yi Jin, Seon-Hwa Lee, Helenius J. Kloosterboer and Trevor M. Penning
Journal of Pharmacology and Experimental Therapeutics March 1, 2006, 316 (3) 1300-1309; DOI: https://doi.org/10.1124/jpet.105.091587
Jump to section
Related Articles
Cited By...
More in this TOC Section
Similar Articles
Advertisement