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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

March 01, 2006; Volume 316,Issue 3

NEUROPHARMACOLOGY

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    Elevation of Endocannabinoid Levels in the Ventrolateral Periaqueductal Grey through Inhibition of Fatty Acid Amide Hydrolase Affects Descending Nociceptive Pathways via Both Cannabinoid Receptor Type 1 and Transient Receptor Potential Vanilloid Type-1 Receptors
    Sabatino Maione, Tiziana Bisogno, Vito de Novellis, Enza Palazzo, Luigia Cristino, Marta Valenti, Stefania Petrosino, Vittorio Guglielmotti, Francesco Rossi and Vincenzo Di Marzo
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 969-982; DOI: https://doi.org/10.1124/jpet.105.093286
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    Cumulative Activation of Akt and Consequent Inhibition of Glycogen Synthase Kinase-3 by Brain-Derived Neurotrophic Factor and Insulin-Like Growth Factor-1 in Cultured Hippocampal Neurons
    Nadine N. Johnson-Farley, Tatyana Travkina and Daniel S. Cowen
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1062-1069; DOI: https://doi.org/10.1124/jpet.105.094433
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    Ex Vivo Imaging of Fatty Acid Amide Hydrolase Activity and Its Inhibition in the Mouse Brain
    Sherrye T. Glaser, S. John Gatley and Andrew N. Gifford
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1088-1097; DOI: https://doi.org/10.1124/jpet.105.094748
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    TrkAd5: A Novel Therapeutic Agent for Treatment of Inflammatory Pain and Asthma
    Judy J. Watson, Mark S. Fahey, Edwin van den Worm, Ferdi Engels, Frans P. Nijkamp, Paul Stroemer, Steve McMahon, Shelley J. Allen and David Dawbarn
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1122-1129; DOI: https://doi.org/10.1124/jpet.105.095844
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    Advantages for Transdermal over Oral Oxybutynin to Treat Overactive Bladder: Muscarinic Receptor Binding, Plasma Drug Concentration, and Salivary Secretion
    Tomomi Oki, Ayako Toma-Okura and Shizuo Yamada
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1137-1145; DOI: https://doi.org/10.1124/jpet.105.094508
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    Brain Cholesterol Synthesis in Mice Is Affected by High Dose of Simvastatin but Not of Pravastatin
    Karin M. Thelen, Katharina M. Rentsch, Ursula Gutteck, Maura Heverin, Maria Olin, Ulla Andersson, Arnold von Eckardstein, Ingemar Björkhem and Dieter Lütjohann
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1146-1152; DOI: https://doi.org/10.1124/jpet.105.094136
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    An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition
    G. R. Dawson, K. A. Maubach, N. Collinson, M. Cobain, B. J. Everitt, A. M. MacLeod, H. I. Choudhury, L. M. McDonald, G. Pillai, W. Rycroft, A. J. Smith, F. Sternfeld, F. D. Tattersall, K. A. Wafford, D. S. Reynolds, G. R. Seabrook and J. R. Atack
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1335-1345; DOI: https://doi.org/10.1124/jpet.105.092320
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    Pharmacological Characterization of Agonists at δ-Containing GABAA Receptors: Functional Selectivity for Extrasynaptic Receptors Is Dependent on the Absence of γ2
    Signe í Stórustovu and Bjarke Ebert
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1351-1359; DOI: https://doi.org/10.1124/jpet.105.092403
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    The δ Subunit of γ-Aminobutyric Acid Type A Receptors Does Not Confer Sensitivity to Low Concentrations of Ethanol
    Cecilia M. Borghese, Signe í Stórustovu, Bjarke Ebert, Murray B. Herd, Delia Belelli, Jeremy J. Lambert, George Marshall, Keith A. Wafford and R. Adron Harris
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1360-1368; DOI: https://doi.org/10.1124/jpet.105.092452

CELLULAR AND MOLECULAR

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    A Trimeric Anti-HER2/neu ScFv and Tumor Necrosis Factor-α Fusion Protein Induces HER2/neu Signaling and Facilitates Repair of Injured Epithelia
    Tzu-Hsuan Huang and Sherie L. Morrison
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 983-991; DOI: https://doi.org/10.1124/jpet.105.095513
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    Glibenclamide-Induced Apoptosis Is Specifically Enhanced by Expression of the Sulfonylurea Receptor Isoform SUR1 but Not by Expression of SUR2B or the Mutant SUR1(M1289T)
    Annette Hambrock, Claudia Bernardo de Oliveira Franz, Sabrina Hiller and Hartmut Osswald
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1031-1037; DOI: https://doi.org/10.1124/jpet.105.097501
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    Linopirdine Modulates Calcium Signaling and Stimulus-Secretion Coupling in Adrenal Chromaffin Cells by Targeting M-Type K+ Channels and Nicotinic Acetylcholine Receptors
    Elvira V. Dzhura, Wenjuan He and Kevin P. M. Currie
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1165-1174; DOI: https://doi.org/10.1124/jpet.105.095570
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    R(+)-Methanandamide and Other Cannabinoids Induce the Expression of Cyclooxygenase-2 and Matrix Metalloproteinases in Human Nonpigmented Ciliary Epithelial Cells
    Susanne Rösch, Robert Ramer, Kay Brune and Burkhard Hinz
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1219-1228; DOI: https://doi.org/10.1124/jpet.105.092858
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    Identification of the Insulin Signaling Cascade in the Regulation of Alpha-Class Glutathione S-Transferase Expression in Primary Cultured Rat Hepatocytes
    Sang K. Kim, Mohamed A. Abdelmegeed and Raymond F. Novak
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1255-1261; DOI: https://doi.org/10.1124/jpet.105.096065
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    Differential Efficacies of Somatostatin Receptor Agonists for G-Protein Activation and Desensitization of Somatostatin Receptor Subtype 4-Mediated Responses
    Mia Engström, Juha-Matti Savola and Siegfried Wurster
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1262-1268; DOI: https://doi.org/10.1124/jpet.105.094128
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    Growth Hormone Determines Sexual Dimorphism of Hepatic Cytochrome P450 3A4 Expression in Transgenic Mice
    Connie Cheung, Ai-Ming Yu, Chong-Sheng Chen, Kristopher W. Krausz, Linda G. Byrd, Lionel Feigenbaum, Robert J. Edwards, David J. Waxman and Frank J. Gonzalez
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1328-1334; DOI: https://doi.org/10.1124/jpet.105.094367
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    Identification of a New Class of Prostaglandin Transporter Inhibitors and Characterization of Their Biological Effects on Prostaglandin E2 Transport
    Yuling Chi, Sonya M. Khersonsky, Young-Tae Chang and Victor L. Schuster
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1346-1350; DOI: https://doi.org/10.1124/jpet.105.091975
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    Traditional Chinese Medicines Wu Wei Zi (Schisandra chinensis Baill) and Gan Cao (Glycyrrhiza uralensis Fisch) Activate Pregnane X Receptor and Increase Warfarin Clearance in Rats
    Ying Mu, Jinnan Zhang, Shimin Zhang, Hong-Hao Zhou, David Toma, Songrong Ren, Leaf Huang, Maria Yaramus, Andrew Baum, Raman Venkataramanan and Wen Xie
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1369-1377; DOI: https://doi.org/10.1124/jpet.105.094342

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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    Molecular Targeting of BCL2 and BCLXL Proteins by Synthetic BCL2 Homology 3 Domain Peptide Enhances the Efficacy of Chemotherapy
    Sonia S. Dharap, Pooja Chandna, Yang Wang, Jayant J. Khandare, Bo Qiu, Stanley Stein and Tamara Minko
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 992-998; DOI: https://doi.org/10.1124/jpet.105.094243

CARDIOVASCULAR

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    Erythropoietin, Modified to Not Stimulate Red Blood Cell Production, Retains Its Cardioprotective Properties
    Chanil Moon, Melissa Krawczyk, Doojin Paik, Thomas Coleman, Michael Brines, Magdalena Juhaszova, Steven J. Sollott, Edward G. Lakatta and Mark I. Talan
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 999-1005; DOI: https://doi.org/10.1124/jpet.105.094854
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    Estrogen Receptor α Mediates Acute Potassium Channel Stimulation in Human Coronary Artery Smooth Muscle Cells
    Guichun Han, Xiuping Yu, Luo Lu, Shuyi Li, Handong Ma, Shu Zhu, Xiuyun Cui and Richard E. White
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1025-1030; DOI: https://doi.org/10.1124/jpet.105.093542
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    Comparative Evaluation of HERG Currents and QT Intervals following Challenge with Suspected Torsadogenic and Nontorsadogenic Drugs
    Alexander N. Katchman, John Koerner, Toshimasa Tosaka, Raymond L. Woosley and Steven N. Ebert
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1098-1106; DOI: https://doi.org/10.1124/jpet.105.093393
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    The Effect of NCX4016 [2-Acetoxy-benzoate 2-(2-nitroxymethyl)-phenyl Ester] on the Consequences of Ischemia and Reperfusion in the Streptozotocin Diabetic Rat
    S. G. Burke, C. L. Wainwright, I. Vojnovic, T. Warner, D. G. Watson and B. L. Furman
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1107-1114; DOI: https://doi.org/10.1124/jpet.105.096339
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    The Urotensin-II Receptor Antagonist Palosuran Improves Pancreatic and Renal Function in Diabetic Rats
    Martine Clozel, Patrick Hess, Changbin Qiu, Shuang-Shuang Ding and Markus Rey
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1115-1121; DOI: https://doi.org/10.1124/jpet.105.094821
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    Fibrin Affinity of Erythrocyte-Coupled Tissue-Type Plasminogen Activators Endures Hemodynamic Forces and Enhances Fibrinolysis in Vivo
    Kumkum Ganguly, Mukul S. Goel, Tatyana Krasik, Khalil Bdeir, Scott L. Diamond, Douglas B. Cines, Vladimir R. Muzykantov and Juan-Carlos Murciano
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1130-1136; DOI: https://doi.org/10.1124/jpet.105.093450
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    Angiotensin I-Converting Enzyme Inhibitors Block Protein Kinase Cϵ by Activating Bradykinin B1 Receptors in Human Endothelial Cells
    Sinisa Stanisavljevic, Tatjana Ignjatovic, Peter A. Deddish, Viktor Brovkovych, Kai Zhang, Ervin G. Erdös and Randal A. Skidgel
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1153-1158; DOI: https://doi.org/10.1124/jpet.105.093849
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    Differential Expression of Components of the Cardiomyocyte Adrenomedullin/Intermedin Receptor System following Blood Pressure Reduction in Nitric Oxide-Deficient Hypertension
    YouYou Zhao, David Bell, Lisa R. Smith, Li Zhao, Adrian B. Devine, Eugene M. McHenry, D. Paul Nicholls and Barbara J. McDermott
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1269-1281; DOI: https://doi.org/10.1124/jpet.105.092783

INFLAMMATION AND IMMUNOPHARMACOLOGY

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    Immunomodulatory Effects of Etanercept in an Experimental Model of Spinal Cord Injury
    Tiziana Genovese, Emanuela Mazzon, Concetta Crisafulli, Rosanna Di Paola, Carmelo Muià, Placido Bramanti and Salvatore Cuzzocrea
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1006-1016; DOI: https://doi.org/10.1124/jpet.105.097188
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    Therapeutic Promise of Proteinase-Activated Receptor-2 Antagonism in Joint Inflammation
    Elizabeth B. Kelso, John C. Lockhart, Todd Hembrough, Lynette Dunning, Robin Plevin, Morley D. Hollenberg, Christian P. Sommerhoff, John S. McLean and William R. Ferrell
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1017-1024; DOI: https://doi.org/10.1124/jpet.105.093807
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    The Phase 2 Enzyme Inducers Ethacrynic Acid, DL-Sulforaphane, and Oltipraz Inhibit Lipopolysaccharide-Induced High-Mobility Group Box 1 Secretion by RAW 264.7 Cells
    Meaghan E. Killeen, Joshua A. Englert, Donna Beer Stolz, Mingchen Song, Yusheng Han, Russell L. Delude, John A. Kellum and Mitchell P. Fink
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1070-1079; DOI: https://doi.org/10.1124/jpet.105.092841
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    S-Adenosyl-l-homocysteine Hydrolase Inactivation Curtails Ovalbumin-Induced Immune Responses
    Yun-Feng Fu, Jun-Xia Wang, Yang Zhao, Yang Yang, Wei Tang, Jia Ni, Yi-Na Zhu, Ru Zhou, Pei-Lan He, Chuan Li, Xiao-Yu Li, Yi-Fu Yang, Brian R. Lawson and Jian-Ping Zuo
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1229-1237; DOI: https://doi.org/10.1124/jpet.105.093369
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    Second-Generation Inhibitors Demonstrate the Involvement of p38 Mitogen-Activated Protein Kinase in Post-Transcriptional Modulation of Inflammatory Mediator Production in Human and Rodent Airways
    Mark A. Birrell, Sissie Wong, Kerryn McCluskie, Matthew C. Catley, Elizabeth L. Hardaker, Saleem Haj-Yahia and Maria G. Belvisi
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1318-1327; DOI: https://doi.org/10.1124/jpet.105.093310

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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    RETRACTION: Opposite Effects of Pre- and Postischemic Treatments with Nitric Oxide Donor on Ischemia/Reperfusion-Induced Renal Injury
    Atsushi Nakajima, Kyoko Ueda, Masanori Takaoka, Yoshiko Yoshimi and Yasuo Matsumura
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1038-1046; DOI: https://doi.org/10.1124/jpet.105.092049
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    Effects of Calcium Channel Blockade on Angiotensin II-Induced Peritubular Ischemia in Rats
    Naoki Kondo, Hideyasu Kiyomoto, Tokunori Yamamoto, Akira Miyatake, Guang-Ping Sun, Matlubur Rahman, Hirofumi Hitomi, Kumiko Moriwaki, Taiga Hara, Shoji Kimura, Youichi Abe, Masakazu Kohno and Akira Nishiyama
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1047-1052; DOI: https://doi.org/10.1124/jpet.105.095331
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    Metformin Prevents Endotoxin-Induced Liver Injury after Partial Hepatectomy
    Ina Bergheim, James P. Luyendyk, Chad Steele, Gilandra K. Russell, Luping Guo, Robert A. Roth and Gavin E. Arteel
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.105.092122
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    Pharmacologic Characterization of Intrinsic Mechanisms Controlling Tone and Relaxation of Porcine Lower Esophageal Sphincter
    Ricard Farré, Mariona Aulí, Begoña Lecea, Emma Martínez and Pere Clavé
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1238-1248; DOI: https://doi.org/10.1124/jpet.105.094482
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    Superoxide Dismutase Mimetic Preserves the Glomerular Capillary Permeability Barrier to Protein
    Pu Duann, Prasun K. Datta, Cynthia Pan, Jeffrey B. Blumberg, Mukut Sharma and Elias A. Lianos
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1249-1254; DOI: https://doi.org/10.1124/jpet.105.092957

TOXICOLOGY

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    Microarray Analysis of Lipopolysaccharide Potentiation of Trovafloxacin-Induced Liver Injury in Rats Suggests a Role for Proinflammatory Chemokines and Neutrophils
    Jeffrey F. Waring, Michael J. Liguori, James P. Luyendyk, Jane F. Maddox, Patricia E. Ganey, Robert F. Stachlewitz, Colin North, Eric A. G. Blomme and Robert A. Roth
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1080-1087; DOI: https://doi.org/10.1124/jpet.105.096347
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    Modulation of Expression of Rat Mitochondrial 2-Oxoglutarate Carrier in NRK-52E Cells Alters Mitochondrial Transport and Accumulation of Glutathione and Susceptibility to Chemically Induced Apoptosis
    Feng Xu, David A. Putt, Larry H. Matherly and Lawrence H. Lash
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1175-1186; DOI: https://doi.org/10.1124/jpet.105.094599
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    Relationship between Temperature, Dopaminergic Neurotoxicity, and Plasma Drug Concentrations in Methamphetamine-Treated Squirrel Monkeys
    Jie Yuan, George Hatzidimitriou, Pranav Suthar, Melanie Mueller, Una McCann and George Ricaurte
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1210-1218; DOI: https://doi.org/10.1124/jpet.105.096503

ENDOCRINE AND DIABETES

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    A Model of Controlled Acute Hyperglycemia in Rats: Effects of Insulin and Glucagon-Like Peptide-1 Analog
    Joy K. Saha, Jinqi Xia, Steven K. Engle, Yun-Fei Chen, Wolfgang Glaesner and Joseph A. Jakubowski
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1159-1164; DOI: https://doi.org/10.1124/jpet.105.093534

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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    Is the Monkey an Appropriate Animal Model to Examine Drug-Drug Interactions Involving Renal Clearance? Effect of Probenecid on the Renal Elimination of H2 Receptor Antagonists
    Harunobu Tahara, Hiroyuki Kusuhara, Michihiro Chida, Eiichi Fuse and Yuichi Sugiyama
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1187-1194; DOI: https://doi.org/10.1124/jpet.105.094052
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    Changes in Pharmacokinetics of Anti-HIV Protease Inhibitors during Pregnancy: The Role of CYP3A and P-glycoprotein
    Anita A. Mathias, Lillian Maggio-Price, Yurong Lai, Anshul Gupta and Jashvant D. Unadkat
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1202-1209; DOI: https://doi.org/10.1124/jpet.105.095406
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    Improving the in Vitro Prediction of in Vivo Central Nervous System Penetration: Integrating Permeability, P-glycoprotein Efflux, and Free Fractions in Blood and Brain
    Scott G. Summerfield, Alexander J. Stevens, Leanne Cutler, Maria del Carmen Osuna, Beverley Hammond, Sac-Pham Tang, Ann Hersey, David J. Spalding and Phil Jeffrey
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1282-1290; DOI: https://doi.org/10.1124/jpet.105.092916
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    Tibolone Metabolism in Human Liver Is Catalyzed by 3α/3β-Hydroxysteroid Dehydrogenase Activities of the Four Isoforms of the Aldo-Keto Reductase (AKR)1C Subfamily
    Stephan Steckelbroeck, Busola Oyesanmi, Yi Jin, Seon-Hwa Lee, Helenius J. Kloosterboer and Trevor M. Penning
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1300-1309; DOI: https://doi.org/10.1124/jpet.105.091587
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    Developmental Expression of Aryl, Estrogen, and Hydroxysteroid Sulfotransferases in Pre- and Postnatal Human Liver
    Zhengbo Duanmu, Amy Weckle, Sevasti B. Koukouritaki, Ronald N. Hines, Josie L. Falany, Charles N. Falany, Thomas A. Kocarek and Melissa Runge-Morris
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1310-1317; DOI: https://doi.org/10.1124/jpet.105.093633

BEHAVIORAL PHARMACOLOGY

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    Comparison of the Antinociceptive Response to Morphine and Morphine-Like Compounds in Male and Female Sprague-Dawley Rats
    Elizabeth M. Peckham and John R. Traynor
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1195-1201; DOI: https://doi.org/10.1124/jpet.105.094276
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    Comparative Cue Generalization Profiles of L-838, 417, SL651498, Zolpidem, CL218,872, Ocinaplon, Bretazenil, Zopiclone, and Various Benzodiazepines in Chlordiazepoxide and Zolpidem Drug Discrimination
    N. R. Mirza, R. J. Rodgers and L. S. Mathiasen
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1291-1299; DOI: https://doi.org/10.1124/jpet.105.094003
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    Do Subtype-Selective γ-Aminobutyric AcidA Receptor Modulators Have a Reduced Propensity to Induce Physical Dependence in Mice?
    N. R. Mirza and E. Ø. Nielsen
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1378-1385; DOI: https://doi.org/10.1124/jpet.105.094474

LETTERS TO THE EDITOR

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    Comments on “Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems”
    Kari T. Kivistö
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1386; DOI: https://doi.org/10.1124/jpet.105.099333
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    Response to Comments on “Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems”
    Yvonne Y. Lau, Hideaki Okochi, Yong Huang and Leslie Z. Benet
    Journal of Pharmacology and Experimental Therapeutics March 2006, 316 (3) 1387; DOI: https://doi.org/10.1124/jpet.105.099473
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Journal of Pharmacology and Experimental Therapeutics: 316 (3)
Journal of Pharmacology and Experimental Therapeutics
Vol. 316, Issue 3
1 Mar 2006
  • Table of Contents
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  • Back Matter (PDF)
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  • NEUROPHARMACOLOGY
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  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • CARDIOVASCULAR
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • TOXICOLOGY
  • ENDOCRINE AND DIABETES
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • BEHAVIORAL PHARMACOLOGY
  • LETTERS TO THE EDITOR
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
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