Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems

Address correspondence to:
Dr. Leslie Z. Benet, Professor, Department of Biopharmaceutical Sciences, 533 Parnassus, Room U-68, University of California, San Francisco, San Francisco, CA 94143-0446. E-mail: benet{at}itsa.ucsf.edu

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: October 2005 to June 2021

	Abstract	Full	Pdf
Oct 2005	9	0	7
Nov 2005	54	0	552
Dec 2005	22	0	219
Jan 2006	98	30	206
Feb 2006	66	77	147
Mar 2006	28	56	87
Apr 2006	38	61	67
May 2006	23	46	66
Jun 2006	13	51	62
Jul 2006	20	35	39
Aug 2006	13	30	32
Sep 2006	27	29	50
Oct 2006	25	37	58
Nov 2006	26	31	40
Dec 2006	19	8	17
Jan 2007	20	28	31
Feb 2007	10	51	46
Mar 2007	10	49	56
Apr 2007	15	40	51
May 2007	10	53	48
Jun 2007	13	32	44
Jul 2007	17	41	56
Aug 2007	12	46	48
Sep 2007	14	43	42
Oct 2007	19	61	69
Nov 2007	11	44	40
Dec 2007	6	40	35
Jan 2008	12	43	49
Feb 2008	16	40	40
Mar 2008	15	48	46
Apr 2008	24	34	36
May 2008	16	40	40
Jun 2008	13	33	47
Jul 2008	22	32	41
Aug 2008	23	43	33
Sep 2008	19	32	30
Oct 2008	19	37	49
Nov 2008	25	39	35
Dec 2008	15	37	37
Jan 2009	25	27	37
Feb 2009	14	31	17
Mar 2009	29	29	41
Apr 2009	19	32	35
May 2009	9	21	24
Jun 2009	17	24	16
Jul 2009	28	22	24
Aug 2009	67	17	20
Sep 2009	23	16	28
Oct 2009	30	25	25
Nov 2009	23	16	22
Dec 2009	28	8	27
Jan 2010	32	30	22
Feb 2010	43	20	16
Mar 2010	19	19	20
Apr 2010	28	47	32
May 2010	36	36	32
Jun 2010	30	18	21
Jul 2010	25	53	36
Aug 2010	26	25	27
Sep 2010	16	23	26
Oct 2010	23	48	35
Nov 2010	24	34	28
Dec 2010	27	33	24
Jan 2011	20	16	15
Feb 2011	24	17	19
Mar 2011	33	31	41
Apr 2011	33	14	28
May 2011	17	19	34
Jun 2011	31	30	41
Jul 2011	24	21	28
Aug 2011	35	24	34
Sep 2011	26	20	32
Oct 2011	23	17	19
Nov 2011	20	9	23
Dec 2011	29	24	34
Jan 2012	29	15	25
Feb 2012	33	25	39
Mar 2012	47	28	34
Apr 2012	24	28	38
May 2012	22	27	26
Jun 2012	25	26	28
Jul 2012	19	29	20
Aug 2012	26	18	18
Sep 2012	25	18	22
Oct 2012	15	20	18
Nov 2012	17	20	31
Dec 2012	16	26	16
Jan 2013	19	24	16
Feb 2013	24	21	17
Mar 2013	28	32	35
Apr 2013	21	16	21
May 2013	24	19	18
Jun 2013	22	22	15
Jul 2013	14	17	22
Aug 2013	11	15	14
Sep 2013	16	11	13
Oct 2013	17	21	16
Nov 2013	28	27	22
Dec 2013	20	22	18
Jan 2014	10	7	15
Feb 2014	3	13	10
Mar 2014	11	14	19
Apr 2014	23	27	31
May 2014	28	16	21
Jun 2014	15	21	20
Jul 2014	20	25	19
Aug 2014	14	12	6
Sep 2014	5	10	8
Oct 2014	20	10	17
Nov 2014	14	11	14
Dec 2014	9	10	14
Jan 2015	17	34	12
Feb 2015	11	11	11
Mar 2015	14	14	30
Apr 2015	19	20	32
May 2015	15	16	19
Jun 2015	7	24	9
Jul 2015	14	12	17
Aug 2015	6	15	8
Sep 2015	25	25	13
Oct 2015	6	18	10
Nov 2015	19	10	19
Dec 2015	19	27	18
Jan 2016	22	22	20
Feb 2016	14	15	8
Mar 2016	21	7	24
Apr 2016	7	16	21
May 2016	11	21	39
Jun 2016	7	15	15
Jul 2016	12	13	24
Aug 2016	8	16	24
Sep 2016	18	14	16
Oct 2016	6	31	25
Nov 2016	8	25	9
Dec 2016	3	21	10
Jan 2017	3	18	8
Feb 2017	4	21	13
Mar 2017	4	17	6
Apr 2017	3	19	7
May 2017	5	21	14
Jun 2017	2	11	5
Jul 2017	2	22	5
Aug 2017	3	33	13
Sep 2017	4	18	11
Oct 2017	24	40	10
Nov 2017	1	18	5
Dec 2017	2	34	5
Jan 2018	2	22	12
Feb 2018	2	31	21
Mar 2018	6	15	12
Apr 2018	2	33	7
May 2018	2	30	15
Jun 2018	0	25	12
Jul 2018	1	12	8
Aug 2018	2	13	12
Sep 2018	9	16	16
Oct 2018	12	32	24
Nov 2018	2	14	27
Dec 2018	18	3	3
Jan 2019	20	3	4
Feb 2019	4	5	2
Mar 2019	29	4	6
Apr 2019	16	4	5
May 2019	12	3	13
Jun 2019	19	2	6
Jul 2019	12	1	8
Aug 2019	13	6	8
Sep 2019	19	5	6
Oct 2019	11	2	1
Nov 2019	40	2	2
Dec 2019	32	8	2
Jan 2020	9	2	1
Feb 2020	17	3	1
Mar 2020	20	5	3
Apr 2020	13	2	3
May 2020	8	4	4
Jun 2020	10	0	0
Jul 2020	11	4	4
Aug 2020	8	4	4
Sep 2020	24	1	1
Oct 2020	19	4	3
Nov 2020	14	3	1
Dec 2020	24	3	2
Jan 2021	19	24	2
Feb 2021	19	28	2
Mar 2021	26	6	3
Apr 2021	11	3	0
May 2021	27	8	2
Jun 2021	9	17	5