Journal of Pharmacology and Experimental Therapeutics: 316 (2)

February 01, 2006; Volume 316,Issue 2

PERSPECTIVES IN PHARMACOLOGY

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Striatal α6^* Nicotinic Acetylcholine Receptors: Potential Targets for Parkinson's Disease Therapy
Maryka Quik and J. Michael McIntosh

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 481-489; DOI: https://doi.org/10.1124/jpet.105.094375

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Nucleoside Ester Prodrug Substrate Specificity of Liver Carboxylesterase
Christopher P. Landowski, Philip L. Lorenzi, Xueqin Song and Gordon L. Amidon

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 572-580; DOI: https://doi.org/10.1124/jpet.105.092726
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In Vivo Evaluation of P-glycoprotein Function at the Blood-Brain Barrier in Nonhuman Primates Using [¹¹C]Verapamil
Young-Joo Lee, Jun Maeda, Hiroyuki Kusuhara, Takashi Okauchi, Motoki Inaji, Yuji Nagai, Shigeru Obayashi, Ryuji Nakao, Kazutoshi Suzuki, Yuichi Sugiyama and Tetsuya Suhara

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 647-653; DOI: https://doi.org/10.1124/jpet.105.088328
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Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems
Yvonne Y. Lau, Hideaki Okochi, Yong Huang and Leslie Z. Benet

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 762-771; DOI: https://doi.org/10.1124/jpet.105.093088
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Repression of Cytochrome P450 Activity in Human Hepatocytes in Vitro by a Novel Hepatotrophic Factor, Augmenter of Liver Regeneration
Wolfgang E. Thasler, Rania Dayoub, Marcus Mühlbauer, Claus Hellerbrand, Thomas Singer, Anja Gräbe, Karl-Walter Jauch, Hans-Jürgen Schlitt and Thomas S. Weiss

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 822-829; DOI: https://doi.org/10.1124/jpet.105.094201
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The Lymph Lipid Precursor Pool Is a Key Determinant of Intestinal Lymphatic Drug Transport
Natalie L. Trevaskis, Christopher J. H. Porter and William N. Charman

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 881-891; DOI: https://doi.org/10.1124/jpet.105.094094

BEHAVIORAL PHARMACOLOGY

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Differential in Vivo Potencies of Naltrexone and 6β-Naltrexol in the Monkey
M. C. Holden Ko, Mary F. Divin, Heeseung Lee, James H. Woods and John R. Traynor

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 772-779; DOI: https://doi.org/10.1124/jpet.105.094409
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Analysis of the Antinociceptive Effect of the Flavonoid Myricitrin: Evidence for a Role of the l-Arginine-Nitric Oxide and Protein Kinase C Pathways
Flavia Carla Meotti, Ana Paula Luiz, Moacir Geraldo Pizzolatti, Cândida A. L. Kassuya, João B. Calixto and Adair R. S. Santos

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 789-796; DOI: https://doi.org/10.1124/jpet.105.092825
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High-Efficacy 5-Hydroxytryptamine 1A Receptor Activation Counteracts Opioid Hyperallodynia and Affective Conditioning
Francis C. Colpaert, Kristof Deseure, Luis Stinus and Hugo Adriaensen

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 892-899; DOI: https://doi.org/10.1124/jpet.105.095109
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Differential Gender-Related Vulnerability to Depression Induction and Converging Antidepressant Responses in Rats
Miao-Kun Sun and Daniel L. Alkon

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 926-932; DOI: https://doi.org/10.1124/jpet.105.093948

CARDIOVASCULAR

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Neuronal Nitric-Oxide Synthase Inhibition Facilitates Adrenergic Neurotransmission in Rat Mesenteric Resistance Arteries
Yukako Hatanaka, Narumi Hobara, Jin Honghua, Shinji Akiyama, Hideki Nawa, Yuta Kobayashi, Fusako Takayama, Yutaka Gomita and Hiromu Kawasaki

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 490-497; DOI: https://doi.org/10.1124/jpet.105.094656
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QT Prolongation Modifies Dynamic Restitution and Hysteresis of the Beat-to-Beat QT-TQ Interval Relationship during Normal Sinus Rhythm under Varying States of Repolarization
Anthony A. Fossa, Todd Wisialowski and Kimberly Crimin

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 498-506; DOI: https://doi.org/10.1124/jpet.105.095471
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MRS2500 [2-Iodo-N⁶-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y₁ Receptor with Strong Antithrombotic Activity in Mice
Béatrice Hechler, Christelle Nonne, Eun Joo Roh, Marco Cattaneo, Jean-Pierre Cazenave, François Lanza, Kenneth A. Jacobson and Christian Gachet

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 556-563; DOI: https://doi.org/10.1124/jpet.105.094037
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Effects of Phytoestrogens on Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2a and Ca²⁺ Uptake into Cardiac Sarcoplasmic Reticulum
Marnie L. Olson, Margaret E. Kargacin, Thomas W. Honeyman, Christopher A. Ward and Gary J. Kargacin

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 628-635; DOI: https://doi.org/10.1124/jpet.105.092940
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Differential Effects of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Vardenafil, and Tadalafil in Rat Aorta
Cleber E. Teixeira, Fernanda B. M. Priviero and R. Clinton Webb

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 654-661; DOI: https://doi.org/10.1124/jpet.105.092544
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Role of Hydrogen Sulfide in the Cardioprotection Caused by Ischemic Preconditioning in the Rat Heart and Cardiac Myocytes
Jin-Song Bian, Qian Chen Yong, Ting-Ting Pan, Zhan-Ning Feng, Muhammed Yusuf Ali, Shufeng Zhou and Philip Keith Moore

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 670-678; DOI: https://doi.org/10.1124/jpet.105.092023
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Tachycardia Caused by A_2A Adenosine Receptor Agonists Is Mediated by Direct Sympathoexcitation in Awake Rats
Arvinder K. Dhalla, Mei-Yee Wong, Wei-Qun Wang, Italo Biaggioni and Luiz Belardinelli

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 695-702; DOI: https://doi.org/10.1124/jpet.105.095323
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Sphingosine 1-Phosphate Induces Endothelial Nitric-Oxide Synthase Activation through Phosphorylation in Human Corpus Cavernosum
Roberta d'Emmanuele di Villa Bianca, Raffaella Sorrentino, Rosalinda Sorrentino, Ciro Imbimbo, Alessandro Palmieri, Ferdinando Fusco, Mario Maggi, Raffaele De Palma, Giuseppe Cirino and Vincenzo Mirone

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 703-708; DOI: https://doi.org/10.1124/jpet.105.093419
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An Increase in Late Sodium Current Potentiates the Proarrhythmic Activities of Low-Risk QT-Prolonging Drugs in Female Rabbit Hearts
Lin Wu, John C. Shryock, Yejia Song and Luiz Belardinelli

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 718-726; DOI: https://doi.org/10.1124/jpet.105.094862
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In Vivo Cardiac Electrophysiologic Effects of a Novel Diphenylphosphine Oxide I_Kur Blocker, (2-Isopropyl-5-methylcyclohexyl) Diphenylphosphine Oxide, in Rat and Nonhuman Primate
Christopher P. Regan, Audrey A. Wallace, Hillary K. Cresswell, Charity L. Atkins and Joseph J. Lynch

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 727-732; DOI: https://doi.org/10.1124/jpet.105.094839
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Attenuation of Vascular Smooth Muscle Cell Proliferation by 1-Cyclohexyl-3-dodecyl Urea Is Independent of Soluble Epoxide Hydrolase Inhibition
Benjamin B. Davis, Christophe Morisseau, John W. Newman, Theresa L. Pedersen, Bruce D. Hammock and Robert H. Weiss

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 815-821; DOI: https://doi.org/10.1124/jpet.105.091876
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Mesenteric Vasoconstriction and Hindquarters Vasodilatation Accompany the Pressor Actions of Exendin-4 in Conscious Rats
Sheila M. Gardiner, Julie E. March, Philip A. Kemp and Terence Bennett

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 852-859; DOI: https://doi.org/10.1124/jpet.105.093104

CELLULAR AND MOLECULAR

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Mapping the Binding Site of Six Nonpeptide Antagonists to the Human V₂-Renal Vasopressin Receptor
Rosemarie Macion-Dazard, Nicholas Callahan, Zhen Xu, Nan Wu, Marc Thibonnier and Menachem Shoham

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 564-571; DOI: https://doi.org/10.1124/jpet.105.095554
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Dominant Role for Calpain in Thromboxane-Induced Neuromicrovascular Endothelial Cytotoxicity
Christiane Quiniou, Florian Sennlaub, Martin H. Beauchamp, Daniella Checchin, Isabelle Lahaie, Sonia Brault, Fernand Gobeil, Mirna Sirinyan, Amna Kooli, Pierre Hardy, Alexey Pshezhetsky and Sylvain Chemtob

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 618-627; DOI: https://doi.org/10.1124/jpet.105.093898
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Antimelanoma Activity of Apoptogenic Carbonyl Scavengers
Georg T. Wondrak, Myron K. Jacobson and Elaine L. Jacobson

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 805-814; DOI: https://doi.org/10.1124/jpet.105.094953
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Oxymetazoline Inhibits Proinflammatory Reactions: Effect on Arachidonic Acid-Derived Metabolites
Ingrid Beck-Speier, Niru Dayal, Erwin Karg, Konrad L. Maier, Gabriele Schumann, Manuela Semmler and Stephan M. Koelsch

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 843-851; DOI: https://doi.org/10.1124/jpet.105.093278
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Direct Block of Human Ether-a-go-go-Related Gene Potassium Channels by Caffeine
S. L. Cockerill and J. S. Mitcheson

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 860-868; DOI: https://doi.org/10.1124/jpet.105.094755

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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DNA Repair Enzyme, O⁶-Methylguanine DNA Methyltransferase, Modulates Cytotoxicity of Camptothecin-Derived Topoisomerase I Inhibitors
Ching-Chuan Kuo, Jin-Fen Liu and Jang-Yang Chang

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 946-954; DOI: https://doi.org/10.1124/jpet.105.095919

ENDOCRINE AND DIABETES

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Blood Glucose-Lowering Nuclear Receptor Agonists Only Partially Normalize Hepatic Gene Expression in db/db Mice
Michael Loffler, Martin Bilban, Mark Reimers, Werner Waldhäusl and Thomas M. Stulnig

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 797-804; DOI: https://doi.org/10.1124/jpet.105.093831

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Adenosine A1 Receptor Antagonist Blunts Urinary Potassium Excretion, but Not Renal Hemodynamic Effects, Induced by Carbonic Anhydrase Inhibitor in Rats
Xiaosun Zhou and Curtis K. Kost

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 530-538; DOI: https://doi.org/10.1124/jpet.105.091462
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Roles of Cyclooxygenase-2 and Prostacyclin/IP Receptors in Mucosal Defense against Ischemia/Reperfusion Injury in Mouse Stomach
Tohru Kotani, Atsushi Kobata, Eiji Nakamura, Kikuko Amagase and Koji Takeuchi

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 547-555; DOI: https://doi.org/10.1124/jpet.105.093195
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Critical Role of Plasminogen Activator Inhibitor-1 in Cholestatic Liver Injury and Fibrosis
Ina Bergheim, Luping Guo, Molly Anne Davis, Ilinca Duveau and Gavin E. Arteel

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 592-600; DOI: https://doi.org/10.1124/jpet.105.095042
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Genetic Variants of the Human Dipeptide Transporter PEPT1
Pascale Anderle, Carsten Uhd Nielsen, Julia Pinsonneault, Pernille Lindskov Krog, Birger Brodin and Wolfgang Sadée

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 636-646; DOI: https://doi.org/10.1124/jpet.105.094615
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A Xanthine-Based Epithelium-Dependent Airway Relaxant KMUP-3 (7-[2-[4-(4-Nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) Increases Respiratory Performance and Protects against Tumor Necrosis Factor-α-Induced Tracheal Contraction, Involving Nitric Oxide Release and Expression of cGMP and Protein Kinase G
Rong-Jyh Lin, Bin-Nan Wu, Yi-Ching Lo, Li-Mei An, Zen-Kong Dai, Young-Tso Lin, Chao-Shun Tang and Ing-Jun Chen

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 709-717; DOI: https://doi.org/10.1124/jpet.105.092171
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Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules
Carlotta E. Groves, Wendy B. Suhre, Nathan J. Cherrington and Stephen H. Wright

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 743-752; DOI: https://doi.org/10.1124/jpet.105.094979
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The Relaxant Activity of 4,7-Dimethyl-1,2,5-oxadiazolo[3,4-d]-pyridazine 1,5,6-Trioxide in the Mouse Corpus Cavernosum
Cemil Göçmen, H. Sinem Büyüknacar, Alexander Ya Kots, Ferid Murad, Olcay Kiroğlu and Eda Karabal Kumcu

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 753-761; DOI: https://doi.org/10.1124/jpet.105.094250
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M₂ and M₃ Muscarinic Receptor Activation of Urinary Bladder Contractile Signal Transduction. I. Normal Rat Bladder
Alan S. Braverman, Amit S. Tibb and Michael R. Ruggieri

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 869-874; DOI: https://doi.org/10.1124/jpet.105.097303
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M₂ and M₃ Muscarinic Receptor Activation of Urinary Bladder Contractile Signal Transduction. II. Denervated Rat Bladder
Alan S. Braverman, Leo R. Doumanian and Michael R. Ruggieri

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 875-880; DOI: https://doi.org/10.1124/jpet.105.094961
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Selective Inhibition of Phosphodiesterase-4 Ameliorates Chronic Colitis and Prevents Intestinal Fibrosis
S. Videla, J. Vilaseca, C. Medina, M. Mourelle, F. Guarner, A. Salas and J.-R. Malagelada

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 940-945; DOI: https://doi.org/10.1124/jpet.105.090837

INFLAMMATION AND IMMUNOPHARMACOLOGY

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Inhibition of Leukocyte Elastase, Polymorphonuclear Chemoinvasion, and Inflammation-Triggered Pulmonary Fibrosis by a 4-Alkyliden-β-lactam with a Galloyl Moiety
Isabella Dell'Aica, Luigi Sartor, Paola Galletti, Daria Giacomini, Arianna Quintavalla, Fiorella Calabrese, Cinzia Giacometti, Enrico Brunetta, Francesco Piazza, Carlo Agostini and Spiridione Garbisa

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 539-546; DOI: https://doi.org/10.1124/jpet.105.096248
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Periplocoside E, an Effective Compound from Periploca sepium Bge, Inhibited T Cell Activation in Vitro and in Vivo
Yi-Na Zhu, Wei-Min Zhao, Yi-Fu Yang, Qun-Fang Liu, Yu Zhou, Jia Tian, Jia Ni, Yun-Feng Fu, Xiang-Gen Zhong, Wei Tang, Ru Zhou, Pei-Lan He, Xiao-Yu Li and Jian-Ping Zuo

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 662-669; DOI: https://doi.org/10.1124/jpet.105.093732
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A Novel Cannabinoid Peripheral Cannabinoid Receptor-Selective Inverse Agonist Blocks Leukocyte Recruitment in Vivo
Charles A. Lunn, Jay S. Fine, Alberto Rojas-Triana, James V. Jackson, Xuedong Fan, Ted T. Kung, Waldemar Gonsiorek, Martin A. Schwarz, Brian Lavey, Joseph A. Kozlowski, Satwant K. Narula, Daniel J. Lundell, R. William Hipkin and Loretta A. Bober

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 780-788; DOI: https://doi.org/10.1124/jpet.105.093500
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δ Opioid Receptors Stimulate Akt-Dependent Phosphorylation of c-jun in T Cells
Nahid A. Shahabi, Kathy McAllen and Burt M. Sharp

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 933-939; DOI: https://doi.org/10.1124/jpet.105.091447

NEUROPHARMACOLOGY

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5-Hydroxytryptamine 1A Receptor Blockade Facilitates Aversive Learning in Mice: Interactions with Cholinergic and Glutamatergic Mechanisms
Nather Madjid, Elin Elvander Tottie, Maria Lüttgen, Björn Meister, Johan Sandin, Alexander Kuzmin, Oliver Stiedl and Sven Ove Ögren

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 581-591; DOI: https://doi.org/10.1124/jpet.105.092262
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Different Effects of Opioid and Cannabinoid Receptor Agonists on C-Fiber-Induced Extracellular Signal-Regulated Kinase Activation in Dorsal Horn Neurons in Normal and Spinal Nerve-Ligated Rats
Yasuhiko Kawasaki, Tatsuro Kohno and Ru-Rong Ji

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 601-607; DOI: https://doi.org/10.1124/jpet.105.093583
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Effects of Exogenous and Endogenous Cannabinoids on GABAergic Neurotransmission between the Caudate-Putamen and the Globus Pallidus in the Mouse
Birgit Engler, Ilka Freiman, Michal Urbanski and Bela Szabo

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 608-617; DOI: https://doi.org/10.1124/jpet.105.092718
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Comparison of Galantamine and Donepezil for Effects on Nerve Growth Factor, Cholinergic Markers, and Memory Performance in Aged Rats
C. M. Hernandez, D. A. Gearhart, V. Parikh, E. J. Hohnadel, L. W. Davis, M. L. Middlemore, S. P. Warsi, J. L. Waller and A. V. Terry

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 679-694; DOI: https://doi.org/10.1124/jpet.105.093047
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Presynaptic α₁ Adrenergic Receptors Differentially Regulate Synaptic Glutamate and GABA Release to Hypothalamic Presympathetic Neurons
Qian Chen, De-Pei Li and Hui-Lin Pan

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 733-742; DOI: https://doi.org/10.1124/jpet.105.094797
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D2-Like Receptors Mediate the Expulsion Phase of Ejaculation Elicited by 8-Hydroxy-2-(di-N-propylamino)tetralin in Rats
Pierre Clément, Jacques Bernabé, Hosein Kami Kia, Laurent Alexandre and François Giuliano

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 830-834; DOI: https://doi.org/10.1124/jpet.105.092411
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Apolipoprotein E-Derived Peptides Block α7 Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes
Elaine A. Gay, Rebecca C. Klein and Jerrel L. Yakel

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 835-842; DOI: https://doi.org/10.1124/jpet.105.095505
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Characterization of Opioid-Binding Sites in Zebrafish Brain
Verónica González-Núñez, Alejandro Barrallo, John R. Traynor and Raquel E. Rodríguez

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 900-904; DOI: https://doi.org/10.1124/jpet.105.093492
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Improved Bioavailability of the mGlu2/3 Receptor Agonist LY354740 Using a Prodrug Strategy: In Vivo Pharmacology of LY544344
Linda M. Rorick-Kehn, Everett J. Perkins, Karen M. Knitowski, John C. Hart, Bryan G. Johnson, Darryle D. Schoepp and David L. McKinzie

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 905-913; DOI: https://doi.org/10.1124/jpet.105.091926
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Iptakalim as a Human Nicotinic Acetylcholine Receptor Antagonist
Jun Hu, Kari Lindenberger, Gang Hu, Hai Wang, Ronald J. Lukas and Jie Wu

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 914-925; DOI: https://doi.org/10.1124/jpet.105.094987
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Novel Compounds That Interact with Both Leukotriene B₄ Receptors and Vanilloid TRPV1 Receptors
Douglas McHugh, R. Shannon McMaster, Roger G. Pertwee, Sucharita Roy, Anu Mahadevan, Raj K. Razdan and Ruth A. Ross

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 955-965; DOI: https://doi.org/10.1124/jpet.105.095992

TOXICOLOGY

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Protective Effect of Type 2 Diabetes on Acetaminophen-Induced Hepatotoxicity in Male Swiss-Webster Mice
Sharmilee P. Sawant, Ankur V. Dnyanmote, Mayurranjan S. Mitra, Jaya Chilakapati, Alan Warbritton, John R. Latendresse and Harihara M. Mehendale

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 507-519; DOI: https://doi.org/10.1124/jpet.105.094326
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Pulmonary Bronchiolar Cytotoxicity and Formation of Dichloroacetyl Lysine Protein Adducts in Mice Treated with Trichloroethylene
Poh-Gek Forkert, Brandie Millen, Lawrence H. Lash, David A. Putt and Burhan I. Ghanayem

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 520-529; DOI: https://doi.org/10.1124/jpet.105.093062

LETTERS TO THE EDITOR

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Comments on “Shift from Biliary to Urinary Elimination of Acetaminophen-Glucuronide in Acetaminophen-Pretreated Rats”
K. Allegaert and D. Tibboel

Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 966-967; DOI: https://doi.org/10.1124/jpet.105.096024

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND DIABETES

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

LETTERS TO THE EDITOR

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