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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

February 01, 2006; Volume 316,Issue 2

PERSPECTIVES IN PHARMACOLOGY

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    Striatal α6* Nicotinic Acetylcholine Receptors: Potential Targets for Parkinson's Disease Therapy
    Maryka Quik and J. Michael McIntosh
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 481-489; DOI: https://doi.org/10.1124/jpet.105.094375

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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    Nucleoside Ester Prodrug Substrate Specificity of Liver Carboxylesterase
    Christopher P. Landowski, Philip L. Lorenzi, Xueqin Song and Gordon L. Amidon
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 572-580; DOI: https://doi.org/10.1124/jpet.105.092726
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    In Vivo Evaluation of P-glycoprotein Function at the Blood-Brain Barrier in Nonhuman Primates Using [11C]Verapamil
    Young-Joo Lee, Jun Maeda, Hiroyuki Kusuhara, Takashi Okauchi, Motoki Inaji, Yuji Nagai, Shigeru Obayashi, Ryuji Nakao, Kazutoshi Suzuki, Yuichi Sugiyama and Tetsuya Suhara
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 647-653; DOI: https://doi.org/10.1124/jpet.105.088328
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    Multiple Transporters Affect the Disposition of Atorvastatin and Its Two Active Hydroxy Metabolites: Application of in Vitro and ex Situ Systems
    Yvonne Y. Lau, Hideaki Okochi, Yong Huang and Leslie Z. Benet
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 762-771; DOI: https://doi.org/10.1124/jpet.105.093088
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    Repression of Cytochrome P450 Activity in Human Hepatocytes in Vitro by a Novel Hepatotrophic Factor, Augmenter of Liver Regeneration
    Wolfgang E. Thasler, Rania Dayoub, Marcus Mühlbauer, Claus Hellerbrand, Thomas Singer, Anja Gräbe, Karl-Walter Jauch, Hans-Jürgen Schlitt and Thomas S. Weiss
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 822-829; DOI: https://doi.org/10.1124/jpet.105.094201
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    The Lymph Lipid Precursor Pool Is a Key Determinant of Intestinal Lymphatic Drug Transport
    Natalie L. Trevaskis, Christopher J. H. Porter and William N. Charman
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 881-891; DOI: https://doi.org/10.1124/jpet.105.094094

BEHAVIORAL PHARMACOLOGY

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    Differential in Vivo Potencies of Naltrexone and 6β-Naltrexol in the Monkey
    M. C. Holden Ko, Mary F. Divin, Heeseung Lee, James H. Woods and John R. Traynor
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 772-779; DOI: https://doi.org/10.1124/jpet.105.094409
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    Analysis of the Antinociceptive Effect of the Flavonoid Myricitrin: Evidence for a Role of the l-Arginine-Nitric Oxide and Protein Kinase C Pathways
    Flavia Carla Meotti, Ana Paula Luiz, Moacir Geraldo Pizzolatti, Cândida A. L. Kassuya, João B. Calixto and Adair R. S. Santos
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 789-796; DOI: https://doi.org/10.1124/jpet.105.092825
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    High-Efficacy 5-Hydroxytryptamine 1A Receptor Activation Counteracts Opioid Hyperallodynia and Affective Conditioning
    Francis C. Colpaert, Kristof Deseure, Luis Stinus and Hugo Adriaensen
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 892-899; DOI: https://doi.org/10.1124/jpet.105.095109
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    Differential Gender-Related Vulnerability to Depression Induction and Converging Antidepressant Responses in Rats
    Miao-Kun Sun and Daniel L. Alkon
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 926-932; DOI: https://doi.org/10.1124/jpet.105.093948

CARDIOVASCULAR

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    Neuronal Nitric-Oxide Synthase Inhibition Facilitates Adrenergic Neurotransmission in Rat Mesenteric Resistance Arteries
    Yukako Hatanaka, Narumi Hobara, Jin Honghua, Shinji Akiyama, Hideki Nawa, Yuta Kobayashi, Fusako Takayama, Yutaka Gomita and Hiromu Kawasaki
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 490-497; DOI: https://doi.org/10.1124/jpet.105.094656
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    QT Prolongation Modifies Dynamic Restitution and Hysteresis of the Beat-to-Beat QT-TQ Interval Relationship during Normal Sinus Rhythm under Varying States of Repolarization
    Anthony A. Fossa, Todd Wisialowski and Kimberly Crimin
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 498-506; DOI: https://doi.org/10.1124/jpet.105.095471
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    MRS2500 [2-Iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y1 Receptor with Strong Antithrombotic Activity in Mice
    Béatrice Hechler, Christelle Nonne, Eun Joo Roh, Marco Cattaneo, Jean-Pierre Cazenave, François Lanza, Kenneth A. Jacobson and Christian Gachet
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 556-563; DOI: https://doi.org/10.1124/jpet.105.094037
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    Effects of Phytoestrogens on Sarcoplasmic/Endoplasmic Reticulum Calcium ATPase 2a and Ca2+ Uptake into Cardiac Sarcoplasmic Reticulum
    Marnie L. Olson, Margaret E. Kargacin, Thomas W. Honeyman, Christopher A. Ward and Gary J. Kargacin
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 628-635; DOI: https://doi.org/10.1124/jpet.105.092940
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    Differential Effects of the Phosphodiesterase Type 5 Inhibitors Sildenafil, Vardenafil, and Tadalafil in Rat Aorta
    Cleber E. Teixeira, Fernanda B. M. Priviero and R. Clinton Webb
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 654-661; DOI: https://doi.org/10.1124/jpet.105.092544
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    Role of Hydrogen Sulfide in the Cardioprotection Caused by Ischemic Preconditioning in the Rat Heart and Cardiac Myocytes
    Jin-Song Bian, Qian Chen Yong, Ting-Ting Pan, Zhan-Ning Feng, Muhammed Yusuf Ali, Shufeng Zhou and Philip Keith Moore
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 670-678; DOI: https://doi.org/10.1124/jpet.105.092023
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    Tachycardia Caused by A2A Adenosine Receptor Agonists Is Mediated by Direct Sympathoexcitation in Awake Rats
    Arvinder K. Dhalla, Mei-Yee Wong, Wei-Qun Wang, Italo Biaggioni and Luiz Belardinelli
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 695-702; DOI: https://doi.org/10.1124/jpet.105.095323
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    Sphingosine 1-Phosphate Induces Endothelial Nitric-Oxide Synthase Activation through Phosphorylation in Human Corpus Cavernosum
    Roberta d'Emmanuele di Villa Bianca, Raffaella Sorrentino, Rosalinda Sorrentino, Ciro Imbimbo, Alessandro Palmieri, Ferdinando Fusco, Mario Maggi, Raffaele De Palma, Giuseppe Cirino and Vincenzo Mirone
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 703-708; DOI: https://doi.org/10.1124/jpet.105.093419
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    An Increase in Late Sodium Current Potentiates the Proarrhythmic Activities of Low-Risk QT-Prolonging Drugs in Female Rabbit Hearts
    Lin Wu, John C. Shryock, Yejia Song and Luiz Belardinelli
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 718-726; DOI: https://doi.org/10.1124/jpet.105.094862
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    In Vivo Cardiac Electrophysiologic Effects of a Novel Diphenylphosphine Oxide IKur Blocker, (2-Isopropyl-5-methylcyclohexyl) Diphenylphosphine Oxide, in Rat and Nonhuman Primate
    Christopher P. Regan, Audrey A. Wallace, Hillary K. Cresswell, Charity L. Atkins and Joseph J. Lynch
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 727-732; DOI: https://doi.org/10.1124/jpet.105.094839
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    Attenuation of Vascular Smooth Muscle Cell Proliferation by 1-Cyclohexyl-3-dodecyl Urea Is Independent of Soluble Epoxide Hydrolase Inhibition
    Benjamin B. Davis, Christophe Morisseau, John W. Newman, Theresa L. Pedersen, Bruce D. Hammock and Robert H. Weiss
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 815-821; DOI: https://doi.org/10.1124/jpet.105.091876
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    Mesenteric Vasoconstriction and Hindquarters Vasodilatation Accompany the Pressor Actions of Exendin-4 in Conscious Rats
    Sheila M. Gardiner, Julie E. March, Philip A. Kemp and Terence Bennett
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 852-859; DOI: https://doi.org/10.1124/jpet.105.093104

CELLULAR AND MOLECULAR

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    Mapping the Binding Site of Six Nonpeptide Antagonists to the Human V2-Renal Vasopressin Receptor
    Rosemarie Macion-Dazard, Nicholas Callahan, Zhen Xu, Nan Wu, Marc Thibonnier and Menachem Shoham
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 564-571; DOI: https://doi.org/10.1124/jpet.105.095554
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    Dominant Role for Calpain in Thromboxane-Induced Neuromicrovascular Endothelial Cytotoxicity
    Christiane Quiniou, Florian Sennlaub, Martin H. Beauchamp, Daniella Checchin, Isabelle Lahaie, Sonia Brault, Fernand Gobeil, Mirna Sirinyan, Amna Kooli, Pierre Hardy, Alexey Pshezhetsky and Sylvain Chemtob
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 618-627; DOI: https://doi.org/10.1124/jpet.105.093898
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    Antimelanoma Activity of Apoptogenic Carbonyl Scavengers
    Georg T. Wondrak, Myron K. Jacobson and Elaine L. Jacobson
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 805-814; DOI: https://doi.org/10.1124/jpet.105.094953
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    Oxymetazoline Inhibits Proinflammatory Reactions: Effect on Arachidonic Acid-Derived Metabolites
    Ingrid Beck-Speier, Niru Dayal, Erwin Karg, Konrad L. Maier, Gabriele Schumann, Manuela Semmler and Stephan M. Koelsch
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 843-851; DOI: https://doi.org/10.1124/jpet.105.093278
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    Direct Block of Human Ether-a-go-go-Related Gene Potassium Channels by Caffeine
    S. L. Cockerill and J. S. Mitcheson
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 860-868; DOI: https://doi.org/10.1124/jpet.105.094755

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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    DNA Repair Enzyme, O6-Methylguanine DNA Methyltransferase, Modulates Cytotoxicity of Camptothecin-Derived Topoisomerase I Inhibitors
    Ching-Chuan Kuo, Jin-Fen Liu and Jang-Yang Chang
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 946-954; DOI: https://doi.org/10.1124/jpet.105.095919

ENDOCRINE AND DIABETES

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    Blood Glucose-Lowering Nuclear Receptor Agonists Only Partially Normalize Hepatic Gene Expression in db/db Mice
    Michael Loffler, Martin Bilban, Mark Reimers, Werner Waldhäusl and Thomas M. Stulnig
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 797-804; DOI: https://doi.org/10.1124/jpet.105.093831

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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    Adenosine A1 Receptor Antagonist Blunts Urinary Potassium Excretion, but Not Renal Hemodynamic Effects, Induced by Carbonic Anhydrase Inhibitor in Rats
    Xiaosun Zhou and Curtis K. Kost
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 530-538; DOI: https://doi.org/10.1124/jpet.105.091462
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    Roles of Cyclooxygenase-2 and Prostacyclin/IP Receptors in Mucosal Defense against Ischemia/Reperfusion Injury in Mouse Stomach
    Tohru Kotani, Atsushi Kobata, Eiji Nakamura, Kikuko Amagase and Koji Takeuchi
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 547-555; DOI: https://doi.org/10.1124/jpet.105.093195
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    Critical Role of Plasminogen Activator Inhibitor-1 in Cholestatic Liver Injury and Fibrosis
    Ina Bergheim, Luping Guo, Molly Anne Davis, Ilinca Duveau and Gavin E. Arteel
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 592-600; DOI: https://doi.org/10.1124/jpet.105.095042
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    Genetic Variants of the Human Dipeptide Transporter PEPT1
    Pascale Anderle, Carsten Uhd Nielsen, Julia Pinsonneault, Pernille Lindskov Krog, Birger Brodin and Wolfgang Sadée
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 636-646; DOI: https://doi.org/10.1124/jpet.105.094615
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    A Xanthine-Based Epithelium-Dependent Airway Relaxant KMUP-3 (7-[2-[4-(4-Nitrobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine) Increases Respiratory Performance and Protects against Tumor Necrosis Factor-α-Induced Tracheal Contraction, Involving Nitric Oxide Release and Expression of cGMP and Protein Kinase G
    Rong-Jyh Lin, Bin-Nan Wu, Yi-Ching Lo, Li-Mei An, Zen-Kong Dai, Young-Tso Lin, Chao-Shun Tang and Ing-Jun Chen
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 709-717; DOI: https://doi.org/10.1124/jpet.105.092171
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    Sex Differences in the mRNA, Protein, and Functional Expression of Organic Anion Transporter (Oat) 1, Oat3, and Organic Cation Transporter (Oct) 2 in Rabbit Renal Proximal Tubules
    Carlotta E. Groves, Wendy B. Suhre, Nathan J. Cherrington and Stephen H. Wright
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 743-752; DOI: https://doi.org/10.1124/jpet.105.094979
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    The Relaxant Activity of 4,7-Dimethyl-1,2,5-oxadiazolo[3,4-d]-pyridazine 1,5,6-Trioxide in the Mouse Corpus Cavernosum
    Cemil Göçmen, H. Sinem Büyüknacar, Alexander Ya Kots, Ferid Murad, Olcay Kiroğlu and Eda Karabal Kumcu
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 753-761; DOI: https://doi.org/10.1124/jpet.105.094250
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    M2 and M3 Muscarinic Receptor Activation of Urinary Bladder Contractile Signal Transduction. I. Normal Rat Bladder
    Alan S. Braverman, Amit S. Tibb and Michael R. Ruggieri
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 869-874; DOI: https://doi.org/10.1124/jpet.105.097303
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    M2 and M3 Muscarinic Receptor Activation of Urinary Bladder Contractile Signal Transduction. II. Denervated Rat Bladder
    Alan S. Braverman, Leo R. Doumanian and Michael R. Ruggieri
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 875-880; DOI: https://doi.org/10.1124/jpet.105.094961
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    Selective Inhibition of Phosphodiesterase-4 Ameliorates Chronic Colitis and Prevents Intestinal Fibrosis
    S. Videla, J. Vilaseca, C. Medina, M. Mourelle, F. Guarner, A. Salas and J.-R. Malagelada
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 940-945; DOI: https://doi.org/10.1124/jpet.105.090837

INFLAMMATION AND IMMUNOPHARMACOLOGY

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    Inhibition of Leukocyte Elastase, Polymorphonuclear Chemoinvasion, and Inflammation-Triggered Pulmonary Fibrosis by a 4-Alkyliden-β-lactam with a Galloyl Moiety
    Isabella Dell'Aica, Luigi Sartor, Paola Galletti, Daria Giacomini, Arianna Quintavalla, Fiorella Calabrese, Cinzia Giacometti, Enrico Brunetta, Francesco Piazza, Carlo Agostini and Spiridione Garbisa
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 539-546; DOI: https://doi.org/10.1124/jpet.105.096248
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    Periplocoside E, an Effective Compound from Periploca sepium Bge, Inhibited T Cell Activation in Vitro and in Vivo
    Yi-Na Zhu, Wei-Min Zhao, Yi-Fu Yang, Qun-Fang Liu, Yu Zhou, Jia Tian, Jia Ni, Yun-Feng Fu, Xiang-Gen Zhong, Wei Tang, Ru Zhou, Pei-Lan He, Xiao-Yu Li and Jian-Ping Zuo
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 662-669; DOI: https://doi.org/10.1124/jpet.105.093732
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    A Novel Cannabinoid Peripheral Cannabinoid Receptor-Selective Inverse Agonist Blocks Leukocyte Recruitment in Vivo
    Charles A. Lunn, Jay S. Fine, Alberto Rojas-Triana, James V. Jackson, Xuedong Fan, Ted T. Kung, Waldemar Gonsiorek, Martin A. Schwarz, Brian Lavey, Joseph A. Kozlowski, Satwant K. Narula, Daniel J. Lundell, R. William Hipkin and Loretta A. Bober
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 780-788; DOI: https://doi.org/10.1124/jpet.105.093500
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    δ Opioid Receptors Stimulate Akt-Dependent Phosphorylation of c-jun in T Cells
    Nahid A. Shahabi, Kathy McAllen and Burt M. Sharp
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 933-939; DOI: https://doi.org/10.1124/jpet.105.091447

NEUROPHARMACOLOGY

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    5-Hydroxytryptamine 1A Receptor Blockade Facilitates Aversive Learning in Mice: Interactions with Cholinergic and Glutamatergic Mechanisms
    Nather Madjid, Elin Elvander Tottie, Maria Lüttgen, Björn Meister, Johan Sandin, Alexander Kuzmin, Oliver Stiedl and Sven Ove Ögren
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 581-591; DOI: https://doi.org/10.1124/jpet.105.092262
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    Different Effects of Opioid and Cannabinoid Receptor Agonists on C-Fiber-Induced Extracellular Signal-Regulated Kinase Activation in Dorsal Horn Neurons in Normal and Spinal Nerve-Ligated Rats
    Yasuhiko Kawasaki, Tatsuro Kohno and Ru-Rong Ji
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 601-607; DOI: https://doi.org/10.1124/jpet.105.093583
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    Effects of Exogenous and Endogenous Cannabinoids on GABAergic Neurotransmission between the Caudate-Putamen and the Globus Pallidus in the Mouse
    Birgit Engler, Ilka Freiman, Michal Urbanski and Bela Szabo
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 608-617; DOI: https://doi.org/10.1124/jpet.105.092718
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    Comparison of Galantamine and Donepezil for Effects on Nerve Growth Factor, Cholinergic Markers, and Memory Performance in Aged Rats
    C. M. Hernandez, D. A. Gearhart, V. Parikh, E. J. Hohnadel, L. W. Davis, M. L. Middlemore, S. P. Warsi, J. L. Waller and A. V. Terry
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 679-694; DOI: https://doi.org/10.1124/jpet.105.093047
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    Presynaptic α1 Adrenergic Receptors Differentially Regulate Synaptic Glutamate and GABA Release to Hypothalamic Presympathetic Neurons
    Qian Chen, De-Pei Li and Hui-Lin Pan
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 733-742; DOI: https://doi.org/10.1124/jpet.105.094797
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    D2-Like Receptors Mediate the Expulsion Phase of Ejaculation Elicited by 8-Hydroxy-2-(di-N-propylamino)tetralin in Rats
    Pierre Clément, Jacques Bernabé, Hosein Kami Kia, Laurent Alexandre and François Giuliano
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 830-834; DOI: https://doi.org/10.1124/jpet.105.092411
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    Apolipoprotein E-Derived Peptides Block α7 Neuronal Nicotinic Acetylcholine Receptors Expressed in Xenopus Oocytes
    Elaine A. Gay, Rebecca C. Klein and Jerrel L. Yakel
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 835-842; DOI: https://doi.org/10.1124/jpet.105.095505
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    Characterization of Opioid-Binding Sites in Zebrafish Brain
    Verónica González-Núñez, Alejandro Barrallo, John R. Traynor and Raquel E. Rodríguez
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 900-904; DOI: https://doi.org/10.1124/jpet.105.093492
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    Improved Bioavailability of the mGlu2/3 Receptor Agonist LY354740 Using a Prodrug Strategy: In Vivo Pharmacology of LY544344
    Linda M. Rorick-Kehn, Everett J. Perkins, Karen M. Knitowski, John C. Hart, Bryan G. Johnson, Darryle D. Schoepp and David L. McKinzie
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 905-913; DOI: https://doi.org/10.1124/jpet.105.091926
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    Iptakalim as a Human Nicotinic Acetylcholine Receptor Antagonist
    Jun Hu, Kari Lindenberger, Gang Hu, Hai Wang, Ronald J. Lukas and Jie Wu
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 914-925; DOI: https://doi.org/10.1124/jpet.105.094987
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    Novel Compounds That Interact with Both Leukotriene B4 Receptors and Vanilloid TRPV1 Receptors
    Douglas McHugh, R. Shannon McMaster, Roger G. Pertwee, Sucharita Roy, Anu Mahadevan, Raj K. Razdan and Ruth A. Ross
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 955-965; DOI: https://doi.org/10.1124/jpet.105.095992

TOXICOLOGY

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    Protective Effect of Type 2 Diabetes on Acetaminophen-Induced Hepatotoxicity in Male Swiss-Webster Mice
    Sharmilee P. Sawant, Ankur V. Dnyanmote, Mayurranjan S. Mitra, Jaya Chilakapati, Alan Warbritton, John R. Latendresse and Harihara M. Mehendale
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 507-519; DOI: https://doi.org/10.1124/jpet.105.094326
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    Pulmonary Bronchiolar Cytotoxicity and Formation of Dichloroacetyl Lysine Protein Adducts in Mice Treated with Trichloroethylene
    Poh-Gek Forkert, Brandie Millen, Lawrence H. Lash, David A. Putt and Burhan I. Ghanayem
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 520-529; DOI: https://doi.org/10.1124/jpet.105.093062

LETTERS TO THE EDITOR

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    Comments on “Shift from Biliary to Urinary Elimination of Acetaminophen-Glucuronide in Acetaminophen-Pretreated Rats”
    K. Allegaert and D. Tibboel
    Journal of Pharmacology and Experimental Therapeutics February 2006, 316 (2) 966-967; DOI: https://doi.org/10.1124/jpet.105.096024
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Journal of Pharmacology and Experimental Therapeutics: 316 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 316, Issue 2
1 Feb 2006
  • Table of Contents
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  • PERSPECTIVES IN PHARMACOLOGY
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • ENDOCRINE AND DIABETES
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
  • LETTERS TO THE EDITOR
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
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