Journal of Pharmacology and Experimental Therapeutics: 315 (3)

December 01, 2005; Volume 315,Issue 3

PERSPECTIVES IN PHARMACOLOGY

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Role of Tyrosine Kinase Inhibitors in Cancer Therapy
Amit Arora and Eric M. Scholar

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 971-979; DOI: https://doi.org/10.1124/jpet.105.084145

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Shift from Biliary to Urinary Elimination of Acetaminophen-Glucuronide in Acetaminophen-Pretreated Rats
Carolina I. Ghanem, María L. Ruiz, Silvina S. M. Villanueva, Marcelo G. Luquita, Viviana A. Catania, Brett Jones, Laura A. Bengochea, Mary Vore and Aldo D. Mottino

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 987-995; DOI: https://doi.org/10.1124/jpet.105.090613
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Visualization of Binding and Transcytosis of Botulinum Toxin by Human Intestinal Epithelial Cells
Chowdhury R. Ahsan, György Hajnóczky, Andrew B. Maksymowych and Lance L. Simpson

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1028-1035; DOI: https://doi.org/10.1124/jpet.105.092213
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Functional Characterization of Novel Allelic Variants of CYP2C9 Recently Discovered in Southeast Asians
Tracy C. DeLozier, Soo-Chin Lee, Sherry J. Coulter, Boon Cher Goh and Joyce A. Goldstein

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1085-1090; DOI: https://doi.org/10.1124/jpet.105.091181
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PEPT2 (Slc15a2)-Mediated Unidirectional Transport of Cefadroxil from Cerebrospinal Fluid into Choroid Plexus
Hong Shen, Richard F. Keep, Yongjun Hu and David E. Smith

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1101-1108; DOI: https://doi.org/10.1124/jpet.105.090654
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Differential UGT1A1 Induction by Chrysin in Primary Human Hepatocytes and HepG2 Cells
Cornelia M. Smith, Richard A. Graham, Wojciech L. Krol, Ivin S. Silver, Masahiko Negishi, Hongbing Wang and Edward L. Lecluyse

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1256-1264; DOI: https://doi.org/10.1124/jpet.105.090795
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Differential Substrate and Inhibitory Activities of Ranitidine and Famotidine toward Human Organic Cation Transporter 1 (hOCT1; SLC22A1), hOCT2 (SLC22A2), and hOCT3 (SLC22A3)
David L. Bourdet, John B. Pritchard and Dhiren R. Thakker

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1288-1297; DOI: https://doi.org/10.1124/jpet.105.091223

BEHAVIORAL PHARMACOLOGY

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Cocaine- and Amphetamine-Regulated Transcript (CART) Peptides Modulate the Locomotor and Motivational Properties of Psychostimulants
Pastor R. Couceyro, Charity Evans, Audra McKinzie, Darrion Mitchell, Matt Dube, Leila Hagshenas, Francis J. White, Jim Douglass, William G. Richards and Anthony W. Bannon

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1091-1100; DOI: https://doi.org/10.1124/jpet.105.091678
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A Selective Allosteric Potentiator of Metabotropic Glutamate (mGlu) 2 Receptors Has Effects Similar to an Orthosteric mGlu2/3 Receptor Agonist in Mouse Models Predictive of Antipsychotic Activity
Ruggero Galici, Nicholas G. Echemendia, Alice L. Rodriguez and P. Jeffrey Conn

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1181-1187; DOI: https://doi.org/10.1124/jpet.105.091074
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Comparison of Intravenous Buprenorphine and Methadone Self-Administration by Recently Detoxified Heroin-Dependent Individuals
Sandra D. Comer, Maria A. Sullivan and Ellen A. Walker

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1320-1330; DOI: https://doi.org/10.1124/jpet.105.090423

CARDIOVASCULAR

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Chronic Exposure to Cocaine Binging Predisposes to an Accelerated Course of Dilated Cardiomyopathy in Conscious Dogs following Rapid Ventricular Pacing
Pratik Parikh, Lazaros A. Nikolaidis, Carol Stolarski, You-Tang Shen and Richard P. Shannon

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1013-1019; DOI: https://doi.org/10.1124/jpet.105.088161
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Rosiglitazone Protects against Ischemia/Reperfusion-Induced Leukocyte Adhesion in the Zucker Diabetic Fatty Rat
Douglas G. Johns, Zhaohui Ao, Marianne Eybye, Alan Olzinski, Melissa Costell, Susan Gruver, Stephen A. Smith, Stephen A. Douglas and Colin H. Macphee

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1020-1027; DOI: https://doi.org/10.1124/jpet.105.090993
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Endothelin Mediates Superoxide Production and Vasoconstriction through Activation of NADPH Oxidase and Uncoupled Nitric-Oxide Synthase in the Rat Aorta
E. Dabbs Loomis, Jennifer C. Sullivan, David A. Osmond, David M. Pollock and Jennifer S. Pollock

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1058-1064; DOI: https://doi.org/10.1124/jpet.105.091728
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Leptin Induces Vascular Smooth Muscle Cell Hypertrophy through Angiotensin II- and Endothelin-1-Dependent Mechanisms and Mediates Stretch-Induced Hypertrophy
Asad Zeidan, Daniel M. Purdham, Venkatesh Rajapurohitam, Sabzali Javadov, Subrata Chakrabarti and Morris Karmazyn

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1075-1084; DOI: https://doi.org/10.1124/jpet.105.091561
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Gender Differences in Cardioprotection against Ischemia/Reperfusion Injury in Adult Rat Hearts: Focus on Akt and Protein Kinase C Signaling
Soochan Bae and Lubo Zhang

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1125-1135; DOI: https://doi.org/10.1124/jpet.105.090803
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Enhanced Inhibition of L-type Ca²⁺ Current by β₃-Adrenergic Stimulation in Failing Rat Heart
Zhu-Shan Zhang, Heng-Jie Cheng, Katsuya Onishi, Nobuyuki Ohte, Thomas Wannenburg and Che-Ping Cheng

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1203-1211; DOI: https://doi.org/10.1124/jpet.105.089672
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Nerve Growth Factor-Induced Migration of Endothelial Cells
Jean-Pierre Dollé, Amir Rezvan, Fred D. Allen, Philip Lazarovici and Peter I. Lelkes

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1220-1227; DOI: https://doi.org/10.1124/jpet.105.093252
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Mechanism of Vasopeptidase Inhibitor-Induced Plasma Extravasation: Comparison of Omapatrilat and the Novel Neutral Endopeptidase 24.11/Angiotensin-Converting Enzyme Inhibitor GW796406
Anthony C. Sulpizio, Mark A. Pullen, Richard M. Edwards, James B. Louttit, Rob West and David P. Brooks

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1306-1313; DOI: https://doi.org/10.1124/jpet.105.084749
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Direct and Irreversible Inhibition of Cyclooxygenase-1 by Nitroaspirin (NCX 4016)
Teresa Corazzi, Mario Leone, Raffaella Maucci, Lanfranco Corazzi and Paolo Gresele

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1331-1337; DOI: https://doi.org/10.1124/jpet.105.089896
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In Vivo Antiarrhythmic and Cardiac Electrophysiologic Effects of a Novel Diphenylphosphine Oxide I_Kur Blocker (2-Isopropyl-5-methylcyclohexyl) Diphenylphosphine Oxide
Gary L. Stump, Audrey A. Wallace, Christopher P. Regan and Joseph J. Lynch

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1362-1367; DOI: https://doi.org/10.1124/jpet.105.092197
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In Vitro Evidence That Carteolol Is a Nonconventional Partial Agonist of Guinea Pig Cardiac β₁-Adrenoceptors: A Comparison with Xamoterol
Maura Floreani, Guglielmina Froldi, Luigi Quintieri, Katia Varani, Pier Andrea Borea, Maria Teresa Dorigo and Paola Dorigo

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1386-1395; DOI: https://doi.org/10.1124/jpet.105.088963

CELLULAR AND MOLECULAR

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BP-1107 [{2-[4-(2,4-Dioxo-thiazolidin-5-ylmethyl)-phenoxy]-ethyl}-methyl-amide]: A Novel Synthetic Thiazolidinedione That Inhibits Epidermal Hyperplasia in Psoriatic Skin-Severe-Combined Immunodeficient Mouse Transplants after Topical Application
Narasimharao Bhagavathula, Kamalakar C. Nerusu, Mahendranath Reddy, Charles N. Ellis, Amar Chittiboyina, Mitchell Avery, Harrihar A. Pershadsingh, Theodore W. Kurtz and James Varani

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 996-1004; DOI: https://doi.org/10.1124/jpet.105.091066
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Transforming Growth Factor-β-Dependent Growth Inhibition in Primary Vascular Smooth Muscle Cells Is p38-Dependent
Ulrike Seay, Daniel Sedding, Stefanie Krick, Matthias Hecker, Werner Seeger and Oliver Eickelberg

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1005-1012; DOI: https://doi.org/10.1124/jpet.105.091249
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The Glucocorticoid Triamcinolone Acetonide Inhibits Osmotic Swelling of Retinal Glial Cells via Stimulation of Endogenous Adenosine Signaling
Ortrud Uckermann, Franziska Kutzera, Antje Wolf, Thomas Pannicke, Andreas Reichenbach, Peter Wiedemann, Sebastian Wolf and Andreas Bringmann

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1036-1045; DOI: https://doi.org/10.1124/jpet.105.092353
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Pyrimethamine (2,4-Diamino-5-p-chlorophenyl-6-ethylpyrimidine) Induces Apoptosis of Freshly Isolated Human T Lymphocytes, Bypassing CD95/Fas Molecule but Involving Its Intrinsic Pathway
Marina Pierdominici, Anna Maria Giammarioli, Lucrezia Gambardella, Marco De Felice, Isabella Quinti, Metello Iacobini, Maurizio Carbonari, Walter Malorni and Antonello Giovannetti

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1046-1057; DOI: https://doi.org/10.1124/jpet.105.086736
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Human UDP-Glucuronosyltransferase 1A5: Identification, Expression, and Activity
Moshe Finel, Xin Li, Dione Gardner-Stephen, Stacie Bratton, Peter I. Mackenzie and Anna Radominska-Pandya

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1143-1149; DOI: https://doi.org/10.1124/jpet.105.091900
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Evaluation of Lipophilins as Determinants of Tumor Cell Response to Estramustine
Jody M. Tucker, Zhanna Lipatova, Vladimir Beljanski, Danyelle M. Townsend and Kenneth D. Tew

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1158-1162; DOI: https://doi.org/10.1124/jpet.105.090860
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Roflumilast Inhibits Lipopolysaccharide-Induced Inflammatory Mediators via Suppression of Nuclear Factor-κB, p38 Mitogen-Activated Protein Kinase, and c-Jun NH₂-Terminal Kinase Activation
Hyun Jeong Kwak, Jin Sook Song, Jun Young Heo, Sung Don Yang, Ji-Youn Nam and Hyae Gyeong Cheon

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1188-1195; DOI: https://doi.org/10.1124/jpet.105.092056
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Cloning, Expression, and Functional Characterization of Human Cyclooxygenase-1 Splicing Variants: Evidence for Intron 1 Retention
Ning Qin, Sui-Po Zhang, Tasha L. Reitz, Jay M. Mei and Christopher M. Flores

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1298-1305; DOI: https://doi.org/10.1124/jpet.105.090944
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Pharmacological Characterization of Human and Murine Neuropeptide S Receptor Variants
Rainer K. Reinscheid, Yan-Ling Xu, Naoe Okamura, Joanne Zeng, Shinjae Chung, Rama Pai, Zhiwei Wang and Olivier Civelli

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1338-1345; DOI: https://doi.org/10.1124/jpet.105.093427
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Functional Domains of the Mouse β₃-Adrenoceptor Associated with Differential G Protein Coupling
Masaaki Sato, Dana S. Hutchinson, Tore Bengtsson, Anders Floren, Ülo Langel, Takahiro Horinouchi, Bronwyn A. Evans and Roger J. Summers

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1354-1361; DOI: https://doi.org/10.1124/jpet.105.091736

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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Role of O⁶-Alkylguanine-DNA Alkyltransferase in Protecting against 1,3-Bis(2-chloroethyl)-1-nitrosourea (BCNU)-Induced Long-Term Toxicities
Ryan J. Hansen, Ramamoorthy Nagasubramanian, Shannon M. Delaney, Mathew M. Cherian, Shang Lin, Scott C. Kogan and M. Eileen Dolan

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1247-1255; DOI: https://doi.org/10.1124/jpet.105.083501
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Ruthenium (II)-Derived Organometallic Compounds Induce Cytostatic and Cytotoxic Effects on Mammalian Cancer Cell Lines through p53-Dependent and p53-Independent Mechanisms
C. Gaiddon, P. Jeannequin, P. Bischoff, M. Pfeffer, C. Sirlin and J. P. Loeffler

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1403-1411; DOI: https://doi.org/10.1124/jpet.105.089342

ENDOCRINE AND DIABETES

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Specific Inhibition of Hormone-Sensitive Lipase Improves Lipid Profile while Reducing Plasma Glucose
Thomas H. Claus, Derek B. Lowe, Yin Liang, Arthur I. Salhanick, Christine Keiper Lubeski, Ling Yang, Lynn Lemoine, Jian Zhu and Kevin B. Clairmont

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1396-1402; DOI: https://doi.org/10.1124/jpet.105.086926

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Vasoconstrictor and Vasodilator Effects of Adenosine in the Mouse Kidney due to Preferential Activation of A1 or A2 Adenosine Receptors
P. B. Hansen, S. Hashimoto, M. Oppermann, Y. Huang, J. P. Briggs and J. Schnermann

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1150-1157; DOI: https://doi.org/10.1124/jpet.105.091017

INFLAMMATION AND IMMUNOPHARMACOLOGY

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Expression of Metallopeptidases and Kinin Receptors in Swine Oropharyngeal Tissues: Effects of Angiotensin I-Converting Enzyme Inhibition and Inflammation
Marie Eve Moreau, Pascal Dubreuil, Giuseppe Molinaro, Miguel Chagnon, Werner Müller-Esterl, Yves Lepage, François Marceau and Albert Adam

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1065-1074; DOI: https://doi.org/10.1124/jpet.105.088005
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Epigallocatechin-3-gallate Impairs Chemokine Production in Human Colon Epithelial Cell Lines
Debora Porath, Christoph Riegger, Juergen Drewe and Joseph Schwager

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1172-1180; DOI: https://doi.org/10.1124/jpet.105.090167

NEUROPHARMACOLOGY

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Perturbation of Voltage-Sensitive Ca²⁺ Channel Function by Volatile Organic Solvents
Timothy J. Shafer, Philip J. Bushnell, Vernon A. Benignus and John J. Woodward

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1109-1118; DOI: https://doi.org/10.1124/jpet.105.090027
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Glucocorticoid Hormone Regulates the Circadian Coordination of μ-Opioid Receptor Expression in Mouse Brainstem
Miyako Yoshida, Satoru Koyanagi, Ayaka Matsuo, Toshihiro Fujioka, Hideto To, Shun Higuchi and Shigehiro Ohdo

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1119-1124; DOI: https://doi.org/10.1124/jpet.105.091488
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A Prostacyclin Receptor Antagonist Inhibits the Sensitized Release of Substance P from Rat Sensory Neurons
Koichi Nakae, Kiyoko Saito, Takashi Iino, Noriyuki Yamamoto, Mayo Wakabayashi, Satoru Yoshikawa, Satoshi Matsushima, Hiroshi Miyashita, Hiromi Sugimoto, Atushi Kiba and Jung Gupta

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1136-1142; DOI: https://doi.org/10.1124/jpet.105.091967
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An Investigation of the Efficacy of Mood Stabilizers in Rodent Models of Prepulse Inhibition
Jacob C. Ong, Suzanne A. Brody, Charles H. Large and Mark A. Geyer

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1163-1171; DOI: https://doi.org/10.1124/jpet.105.090845
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Isolation and Pharmacological Characterization of Cannitoxin, a Presynaptic Neurotoxin from the Venom of the Papuan Taipan (Oxyuranus scutellatus canni)
Sanjaya Kuruppu, Shane Reeve, Yajnavalka Banerjee, R. Manjunatha Kini, A. Ian Smith and Wayne C. Hodgson

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1196-1202; DOI: https://doi.org/10.1124/jpet.105.093641
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Allosteric Potentiators of Metabotropic Glutamate Receptor Subtype 5 Have Differential Effects on Different Signaling Pathways in Cortical Astrocytes
Yongqin Zhang, Alice L. Rodriguez and P. Jeffrey Conn

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1212-1219; DOI: https://doi.org/10.1124/jpet.105.090308
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Modulation of Agonist Binding to Human Dopamine Receptor Subtypes by l-Prolyl-l-leucyl-glycinamide and a Peptidomimetic Analog
Vaneeta Verma, Amandeep Mann, Willard Costain, Giuseppe Pontoriero, Jessica M. Castellano, Kevin Skoblenick, Suresh K. Gupta, Zdenek Pristupa, Hyman B. Niznik, Rodney L. Johnson, Venugopalan D. Nair and Ram K. Mishra

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1228-1236; DOI: https://doi.org/10.1124/jpet.105.091256
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Tolperisone-Type Drugs Inhibit Spinal Reflexes via Blockade of Voltage-Gated Sodium and Calcium Channels
Pál Kocsis, Sándor Farkas, László Fodor, Norbert Bielik, Márta Thán, Sándor Kolok, Anikó Gere, Mónika Csejtei and István Tarnawa

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1237-1246; DOI: https://doi.org/10.1124/jpet.105.089805
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Preclinical Pharmacology of FMPD [6-Fluoro-10-[3-(2-methoxyethyl)-4-methyl-piperazin-1-yl]-2-methyl-4H-3-thia-4,9-diaza-benzo[f]azulene]: A Potential Novel Antipsychotic with Lower Histamine H₁ Receptor Affinity Than Olanzapine
Kurt Rasmussen, Mark J. Benvenga, Frank P. Bymaster, David O. Calligaro, Ilene R. Cohen, Julie F. Falcone, Susan K. Hemrick-Luecke, Fionna M. Martin, Nicholas A. Moore, Laura K. Nisenbaum, John M. Schaus, Sarah J. Sundquist, David E. Tupper, Todd R. Wiernicki and David L. Nelson

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1265-1277; DOI: https://doi.org/10.1124/jpet.105.089326
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Intrinsic Efficacy of Antipsychotics at Human D₂, D₃, and D₄ Dopamine Receptors: Identification of the Clozapine Metabolite N-Desmethylclozapine as a D₂/D₃ Partial Agonist
E. S. Burstein, J. Ma, S. Wong, Y. Gao, E. Pham, A. E. Knapp, N. R. Nash, R. Olsson, R. E. Davis, U. Hacksell, D. M. Weiner and M. R. Brann

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1278-1287; DOI: https://doi.org/10.1124/jpet.105.092155
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Unequal Neuroprotection Afforded by the Acetylcholinesterase Inhibitors Galantamine, Donepezil, and Rivastigmine in SH-SY5Y Neuroblastoma Cells: Role of Nicotinic Receptors
Esperanza Arias, Sonia Gallego-Sandín, Mercedes Villarroya, Antonio G. García and Manuela G. López

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1346-1353; DOI: https://doi.org/10.1124/jpet.105.090365
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Expression of the Third Intracellular Loop of the δ-Opioid Receptor Inhibits Signaling by Opioid Receptors and Other G Protein-Coupled Receptors
Evangelia Morou and Zafiroula Georgoussi

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1368-1379; DOI: https://doi.org/10.1124/jpet.105.089946
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Orexin 1 Receptor Activation Attenuates Neurogenic Dural Vasodilation in an Animal Model of Trigeminovascular Nociception
P. R. Holland, S. Akerman and P. J. Goadsby

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1380-1385; DOI: https://doi.org/10.1124/jpet.105.090951

TOXICOLOGY

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Primaquine-Induced Hemolytic Anemia: Role of Splenic Macrophages in the Fate of 5-Hydroxyprimaquine-Treated Rat Erythrocytes
Zachary S. Bowman, David J. Jollow and David C. McMillan

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 980-986; DOI: https://doi.org/10.1124/jpet.105.090407
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Modulation of Cytochrome c Oxidase-Va Is Possibly Involved in Metallothionein Protection from Doxorubicin Cardiotoxicity
Kevyn E. Merten, Wenke Feng, Li Zhang, William Pierce, Jian Cai, Jon B. Klein and Y. James Kang

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1314-1319; DOI: https://doi.org/10.1124/jpet.105.089763

LETTERS TO THE EDITOR

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Comments on “Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties”
Daniel L. Simmons, N. V. Chandrasekharan, Dai Hu, K. Lamar Roos and Joshua Tomsik

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1412-1414; DOI: https://doi.org/10.1124/jpet.105.094169
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Response to Comments on “Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties”
Bela Kis, James A. Snipes and David W. Busija

Journal of Pharmacology and Experimental Therapeutics December 2005, 315 (3) 1415-1416; DOI: https://doi.org/10.1124/jpet.105.094870

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND DIABETES

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

LETTERS TO THE EDITOR

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