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Journal of Pharmacology and Experimental Therapeutics

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Table of Contents

October 01, 2005; Volume 315,Issue 1

PERSPECTIVES IN PHARMACOLOGY

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    Acetaminophen and the Cyclooxygenase-3 Puzzle: Sorting out Facts, Fictions, and Uncertainties
    Bela Kis, James A. Snipes and David W. Busija
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 1-7; DOI: https://doi.org/10.1124/jpet.105.085431

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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    Uptake of l-Carnitine and Its Short-Chain Ester Propionyl-l-carnitine in the Isolated Perfused Rat Liver
    Angelo Mancinelli, Allan M. Evans, Roger L. Nation and Antonio Longo
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 118-124; DOI: https://doi.org/10.1124/jpet.105.087890
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    Multiple Components of 2,4-Dichlorophenoxyacetic Acid Uptake by Rat Choroid Plexus
    Simon Lowes, Destiny Sykes, Christopher M. Breen, Leigh J. Ragone and David S. Miller
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 136-143; DOI: https://doi.org/10.1124/jpet.105.087056
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    Distribution of the Novel Antifolate Pemetrexed to the Brain
    Haiqing Dai, Ying Chen and William F. Elmquist
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 222-229; DOI: https://doi.org/10.1124/jpet.105.090043
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    Role and Relevance of Peptide Transporter 2 (PEPT2) in the Kidney and Choroid Plexus: In Vivo Studies with Glycylsarcosine in Wild-Type and PEPT2 Knockout Mice
    Scott M. Ocheltree, Hong Shen, Yongjun Hu, Richard F. Keep and David E. Smith
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 240-247; DOI: https://doi.org/10.1124/jpet.105.089359
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    Oxidation of Anthracyclines by Peroxidase Metabolites of Salicylic Acid
    Krzysztof J. Reszka, Laura H. Britigan and Bradley E. Britigan
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 283-290; DOI: https://doi.org/10.1124/jpet.105.089417
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    A Species Difference in the Transport Activities of H2 Receptor Antagonists by Rat and Human Renal Organic Anion and Cation Transporters
    Harunobu Tahara, Hiroyuki Kusuhara, Hitoshi Endou, Hermann Koepsell, Tomoki Imaoka, Eiichi Fuse and Yuichi Sugiyama
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 337-345; DOI: https://doi.org/10.1124/jpet.105.088104
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    Influence of Atorvastatin on Apolipoprotein E and AI Kinetics in Patients with Type 2 Diabetes
    K. Bach-Ngohou, K. Ouguerram, R. Frénais, P. Maugère, B. Ripolles-Piquer, Y. Zaïr, M. Krempf and J. M. Bard
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 363-369; DOI: https://doi.org/10.1124/jpet.105.085522
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    Vascular Binding, Blood Flow, Transporter, and Enzyme Interactions on the Processing of Digoxin in Rat Liver
    Lichuan Liu, Ernie Mak, Rommel G. Tirona, Eugene Tan, Phyllis M. Novikoff, Pijun Wang, Allan W. Wolkoff and K. Sandy Pang
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 433-448; DOI: https://doi.org/10.1124/jpet.105.088039

BEHAVIORAL PHARMACOLOGY

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    Neurotensin-Deficient Mice Have Deficits in Prepulse Inhibition: Restoration by Clozapine but Not Haloperidol, Olanzapine, or Quetiapine
    Becky Kinkead, Paul R. Dobner, Vasili Egnatashvili, Tiesha Murray, Nancy Deitemeyer and Charles B. Nemeroff
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 256-264; DOI: https://doi.org/10.1124/jpet.105.087437
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    Relationship between in Vivo Occupancy at the Dopamine Transporter and Behavioral Effects of Cocaine, GBR 12909 [1-{2-[Bis-(4-fluorophenyl)methoxy]ethyl}-4-(3-phenylpropyl)piperazine], and Benztropine Analogs
    Rajeev I. Desai, Theresa A. Kopajtic, Dawn French, Amy H. Newman and Jonathan L. Katz
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 397-404; DOI: https://doi.org/10.1124/jpet.105.091231
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    Differential Behavioral Tolerance to the δ-Opioid Agonist SNC80 ([(+)-4-[(αR)-α-[(2S,5R)-2,5-Dimethyl-4-(2-propenyl)-1-piperazinyl]-(3-methoxyphenyl)methyl]-N,N-diethylbenzamide) in Sprague-Dawley Rats
    Emily M. Jutkiewicz, Sarah T. Kaminsky, Kenner C. Rice, John R. Traynor and James H. Woods
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 414-422; DOI: https://doi.org/10.1124/jpet.105.088831
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    Effects of the Competitive N-Methyl-d-aspartate Receptor Antagonist, LY235959 [(-)-6-Phosphonomethyl-deca-hydroisoquinoline-3-carboxylic Acid], on Responding for Cocaine under Both Fixed and Progressive Ratio Schedules of Reinforcement
    Richard M. Allen, Regina M. Carelli, Linda A. Dykstra, Therese L. Suchey and Carson V. Everett
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 449-457; DOI: https://doi.org/10.1124/jpet.105.086355

CARDIOVASCULAR

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    Mechanisms Underlying the Effects of the Pyrethroid Tefluthrin on Action Potential Duration in Isolated Rat Ventricular Myocytes
    C. Ian Spencer and James S. K. Sham
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 16-23; DOI: https://doi.org/10.1124/jpet.105.084822
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    Early and Sustained Inhibition of Nuclear Factor-κB Prevents Hypertension in Spontaneously Hypertensive Rats
    Bernardo Rodríguez-Iturbe, Atilio Ferrebuz, Valentina Vanegas, Yasmir Quiroz, Sergio Mezzano and Nosratola D. Vaziri
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 51-57; DOI: https://doi.org/10.1124/jpet.105.088062
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    The Role of Akt and Mitogen-Activated Protein Kinase Systems in the Protective Effect of Poly(ADP-Ribose) Polymerase Inhibition in Langendorff Perfused and in Isoproterenol-Damaged Rat Hearts
    Anita Pálfi, Ambrus Tóth, Győző Kulcsár, Katalin Hantó, Péter Deres, Éva Bartha, Róbert Halmosi, Eszter Szabados, László Czopf, Tamás Kálai, Kálmán Hideg, Balázs Sümegi and Kálmán Tóth
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 273-282; DOI: https://doi.org/10.1124/jpet.105.088336
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    Calcium Channel Blocker Inhibits Western-Type Diet-Evoked Atherosclerosis Development in ApoE-Deficient Mice
    Jan Kyselovic, Peter Martinka, Zuzana Batova, Andrea Gazova and Theophile Godfraind
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 320-328; DOI: https://doi.org/10.1124/jpet.105.089847

CELLULAR AND MOLECULAR

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    Transfection of Cytochrome P4504B1 into the Cornea Increases Angiogenic Activity of the Limbal Vessels
    Alexandre Mezentsev, Vladimir Mastyugin, Francesca Seta, Silvia Ashkar, Rowena Kemp, D. Sudarshan Reddy, John R. Falck, Michael W. Dunn and Michal Laniado-Schwartzman
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 42-50; DOI: https://doi.org/10.1124/jpet.105.088211
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    Potentiation of P2X1 ATP-Gated Currents by 5-Hydroxytryptamine 2A Receptors Involves Diacylglycerol-Dependent Kinases and Intracellular Calcium
    Ariel R. Ase, Ramin Raouf, Danny Bélanger, Édith Hamel and Philippe Séguéla
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 144-154; DOI: https://doi.org/10.1124/jpet.105.089045
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    Proerectile Effects of the Rho-Kinase Inhibitor (S)-(+)-2-Methyl-1-[(4-methyl-5-isoquinolinyl)sulfonyl]homopiperazine (H-1152) in the Rat Penis
    Cleber E. Teixeira, Zhekang Ying and R. Clinton Webb
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 155-162; DOI: https://doi.org/10.1124/jpet.105.086041
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    Acetoacetate Induces CYP2E1 Protein and Suppresses CYP2E1 mRNA in Primary Cultured Rat Hepatocytes
    Mohamed A. Abdelmegeed, Nicholas J. Carruthers, Kimberley J. Woodcroft, Sang K. Kim and Raymond F. Novak
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 203-213; DOI: https://doi.org/10.1124/jpet.105.084608
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    Chronic Morphine Up-Regulates Gα12 and Cytoskeletal Proteins in Chinese Hamster Ovary Cells Expressing the Cloned μ Opioid Receptor
    Heng Xu, Xiaoying Wang, Darin Zimmerman, Emily S. Boja, Jiabei Wang, Edward J. Bilsky and Richard B. Rothman
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 248-255; DOI: https://doi.org/10.1124/jpet.105.089367
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    Persistent Binding and Functional Antagonism by Xanomeline at the Muscarinic M5 Receptor
    Marianne K. O. Grant and Esam E. El-Fakahany
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 313-319; DOI: https://doi.org/10.1124/jpet.105.090134
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    Identification of Molecular Targets of the Oligomeric Nonprenylated Acylphloroglucinols from Myrtus communis and Their Implication as Anti-Inflammatory Compounds
    Christian Feißt, Lutz Franke, Giovanni Appendino and Oliver Werz
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 389-396; DOI: https://doi.org/10.1124/jpet.105.090720

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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    Inhibitory Effects of 12-O-Tetradecanoylphorbol-13-acetate Alone or in Combination with All-trans Retinoic Acid on the Growth of Cultured Human Pancreas Cancer Cells and Pancreas Tumor Xenografts in Immunodeficient Mice
    Gina E. Avila, Xi Zheng, Xiao Xing Cui, Amanda D. Ryan, Annette Hansson, Junghan Suh, Arnold B. Rabson, Richard L. Chang, Weichung Joe Shih, Yong Lin, Pamela Crowell, Yao Ping Lu, You Rong Lou and Allan H. Conney
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 170-187; DOI: https://doi.org/10.1124/jpet.105.087585
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    The Repression of E2F-1 Is Critical for the Activity of Minerval against Cancer
    Jordi Martínez, Antonio Gutiérrez, Jesús Casas, Victoria Lladó, Alicia López-Bellan, Joan Besalduch, Ana Dopazo and Pablo V. Escribá
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 466-474; DOI: https://doi.org/10.1124/jpet.105.088716

ENDOCRINE AND DIABETES

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    The Para Substituent of S-3-(Phenoxy)-2-hydroxy-2-methyl-N-(4-nitro-3-trifluoromethyl-phenyl)-propionamides Is a Major Structural Determinant of in Vivo Disposition and Activity of Selective Androgen Receptor Modulators
    Juhyun Kim, Di Wu, Dong Jin Hwang, Duane D. Miller and James T. Dalton
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 230-239; DOI: https://doi.org/10.1124/jpet.105.088344

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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    Modification of Heat Shock Protein 90 by 4-Hydroxynonenal in a Rat Model of Chronic Alcoholic Liver Disease
    David L. Carbone, Jonathan A. Doorn, Zachary Kiebler, Brian R. Ickes and Dennis R. Petersen
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 8-15; DOI: https://doi.org/10.1124/jpet.105.088088
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    Proapoptotic Effect on Normal and Tumor Intestinal Cells of Cytostatic Drugs with Enterohepatic Organotropism
    Maria J. Monte, Maria R. Ballestero, Oscar Briz, Maria J. Perez and Jose J. G. Marin
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 24-35; DOI: https://doi.org/10.1124/jpet.105.086165
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    Cross-Talk between Farnesoid-X-Receptor (FXR) and Peroxisome Proliferator-Activated Receptor γ Contributes to the Antifibrotic Activity of FXR Ligands in Rodent Models of Liver Cirrhosis
    Stefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, Barbara Renga, Andrea Mencarelli, Luisa Riccardi, Antonio Morelli, Mark Pruzanski and Roberto Pellicciari
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 58-68; DOI: https://doi.org/10.1124/jpet.105.085597
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    A Novel A1 Adenosine Receptor Antagonist, L-97-1 [3-[2-(4-Aminophenyl)-ethyl]-8-benzyl-7-{2-ethyl-(2-hydroxy-ethyl)-amino]-ethyl}-1-propyl-3,7-dihydro-purine-2,6-dione], Reduces Allergic Responses to House Dust Mite in an Allergic Rabbit Model of Asthma
    P. C. M. Obiefuna, V. K. Batra, A. Nadeem, P. Borron, C. N. Wilson and S. Jamal Mustafa
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 329-336; DOI: https://doi.org/10.1124/jpet.105.088179
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    Development of Simplified Vasoactive Intestinal Peptide Analogs with Receptor Selectivity and Stability for Human Vasoactive Intestinal Peptide/Pituitary Adenylate Cyclase-Activating Polypeptide Receptors
    Hisato Igarashi, Tetsuhide Ito, Samuel A. Mantey, Tapas K. Pradhan, Wei Hou, David H. Coy and Robert T. Jensen
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 370-381; DOI: https://doi.org/10.1124/jpet.105.088823
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    Mechanisms Underlying Capsaicin-Stimulated Formula Secretion in the Stomach: Comparison with Mucosal Acidification
    Eitaro Aihara, Masamune Hayashi, Yoko Sasaki, Atsushi Kobata and Koji Takeuchi
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 423-432; DOI: https://doi.org/10.1124/jpet.105.087619
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    Inhibition of Nitric-Oxide Synthase Enhances Antigen-Induced Contractions and Increases Release of Cysteinyl-Leukotrienes in Guinea Pig Lung Parenchyma: Nitric Oxide as a Protective Factor
    Anna-Karin Larsson, Magnus Bäck, Josephine Hjoberg and Sven-Erik Dahlén
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 458-465; DOI: https://doi.org/10.1124/jpet.105.086694

INFLAMMATION AND IMMUNOPHARMACOLOGY

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    A-770041, a Novel and Selective Small-Molecule Inhibitor of Lck, Prevents Heart Allograft Rejection
    Robert F. Stachlewitz, Michelle A. Hart, Brian Bettencourt, Tegest Kebede, Annette Schwartz, Sheldon E. Ratnofsky, David J. Calderwood, Wendy O. Waegell and Gavin C. Hirst
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 36-41; DOI: https://doi.org/10.1124/jpet.105.089169
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    Nanoparticles Enhance Therapeutic Efficiency by Selectively Increased Local Drug Dose in Experimental Colitis in Rats
    Alf Lamprecht, Hiromitsu Yamamoto, Hirofumi Takeuchi and Yoshiaki Kawashima
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 196-202; DOI: https://doi.org/10.1124/jpet.105.088146
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    Collagen and Aggrecan Degradation Is Blocked in Interleukin-1-Treated Cartilage Explants by an Inhibitor of IκB Kinase through Suppression of Metalloproteinase Expression
    Mark A. Pattoli, John F. MacMaster, Kurt R. Gregor and James R. Burke
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 382-388; DOI: https://doi.org/10.1124/jpet.105.087569

NEUROPHARMACOLOGY

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    Measurement of the Proportion of D2 Receptors Configured in State of High Affinity for Agonists in Vivo: A Positron Emission Tomography Study Using [11C]N-Propyl-norapomorphine and [11C]Raclopride in Baboons
    Rajesh Narendran, Dah-Ren Hwang, Mark Slifstein, Yuying Hwang, Yiyun Huang, Jesper Ekelund, Olivier Guillin, Erica Scher, Diana Martinez and Marc Laruelle
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 80-90; DOI: https://doi.org/10.1124/jpet.105.090068
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    Evidence for the Existence of an Additional Class of Neuropeptide Y Receptor Sites in Rat Brain
    Yvan Dumont, Emmanuel Moyse, Alain Fournier and Rémi Quirion
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 99-108; DOI: https://doi.org/10.1124/jpet.105.089300
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    Differential Effects of the 5-Hydroxytryptamine (5-HT)1A Receptor Inverse Agonists Rec 27/0224 and Rec 27/0074 on Electrophysiological Responses to 5-HT1A Receptor Activation in Rat Dorsal Raphe Nucleus and Hippocampus in Vitro
    Renato Corradetti, Boris Mlinar, Chiara Falsini, Anna Maria Pugliese, Antonio Cilia, Carla Destefani and Rodolfo Testa
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 109-117; DOI: https://doi.org/10.1124/jpet.105.087809
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    Modulation of N-Methyl-d-aspartate Receptors by Donepezil in Rat Cortical Neurons
    Shigeki Moriguchi, Xilong Zhao, William Marszalec, Jay Z. Yeh and Toshio Narahashi
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 125-135; DOI: https://doi.org/10.1124/jpet.105.087908
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    Radioligand Binding Properties and Pharmacological Characterization of 6-Amino-N-cyclohexyl-N,3-dimethylthiazolo[3,2-a]benzimidazole-2-carboxamide (YM-298198), a High-Affinity, Selective, and Noncompetitive Antagonist of Metabotropic Glutamate Receptor Type 1
    Atsuyuki Kohara, Takashi Toya, Seiji Tamura, Tomonari Watabiki, Yukinori Nagakura, Yoshitsugu Shitaka, Satoshi Hayashibe, Shigeki Kawabata and Masamichi Okada
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 163-169; DOI: https://doi.org/10.1124/jpet.105.087171
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    The Histaminergic Signaling System Exerts a Neuroprotective Role against Neurodegenerative-Induced Processes in the Hamster
    Marcello Canonaco, Maria Madeo, Raffaella Alò, Giuseppina Giusi, Teresa Granata, Antonio Carelli, Alessia Canonaco and Rosa Maria Facciolo
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 188-195; DOI: https://doi.org/10.1124/jpet.105.088153
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    G-Protein Activation by Neurokinin-1 Receptors Is Dynamically Regulated during Persistent Nociception
    Michelle K. Winter and Kenneth E. McCarson
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 214-221; DOI: https://doi.org/10.1124/jpet.105.089565
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    Contrasting Contribution of 5-Hydroxytryptamine 1A Receptor Activation to Neurochemical Profile of Novel Antipsychotics: Frontocortical Dopamine and Hippocampal Serotonin Release in Rat Brain
    Marie-Bernadette Assié, Véronique Ravailhe, Valérie Faucillon and Adrian Newman-Tancredi
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 265-272; DOI: https://doi.org/10.1124/jpet.105.087163
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    Progress toward Acetate Supplementation Therapy for Canavan Disease: Glyceryl Triacetate Administration Increases Acetate, but Not N-Acetylaspartate, Levels in Brain
    Raji Mathew, Peethambaran Arun, Chikkathur N. Madhavarao, John R. Moffett and M. A. Aryan Namboodiri
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 297-303; DOI: https://doi.org/10.1124/jpet.105.087536
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    Novel Cyclic γ-Hydroxybutyrate (GHB) Analogs with High Affinity and Stereoselectivity of Binding to GHB Sites in Rat Brain
    Petrine Wellendorph, Signe Høg, Jeremy R. Greenwood, Anne de Lichtenberg, Birgitte Nielsen, Bente Frølund, Lotte Brehm, Rasmus P. Clausen and Hans Bräuner-Osborne
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 346-351; DOI: https://doi.org/10.1124/jpet.105.090472
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    Block of Delayed-Rectifier Potassium Channels by Reduced Haloperidol and Related Compounds in Mouse Cortical Neurons
    Shi-Bing Yang, Felix Major, Lutz F. Tietze and Marjan Rupnik
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 352-362; DOI: https://doi.org/10.1124/jpet.105.086561
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    The P2X3 Antagonist P1, P5-Di[inosine-5′] Pentaphosphate Binds to the Desensitized State of the Receptor in Rat Dorsal Root Ganglion Neurons
    Kristen K. Ford, Michele Matchett, James E. Krause and Weifeng Yu
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 405-413; DOI: https://doi.org/10.1124/jpet.105.088070

TOXICOLOGY

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    Dieldrin Induces Ubiquitin-Proteasome Dysfunction in α-Synuclein Overexpressing Dopaminergic Neuronal Cells and Enhances Susceptibility to Apoptotic Cell Death
    Faneng Sun, Vellareddy Anantharam, Calivarathan Latchoumycandane, Arthi Kanthasamy and Anumantha G. Kanthasamy
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 69-79; DOI: https://doi.org/10.1124/jpet.105.084632
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    Amphetamine Treatment Similar to That Used in the Treatment of Adult Attention-Deficit/Hyperactivity Disorder Damages Dopaminergic Nerve Endings in the Striatum of Adult Nonhuman Primates
    George A. Ricaurte, Annis O. Mechan, Jie Yuan, George Hatzidimitriou, Tao Xie, Andrew H. Mayne and Una D. McCann
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 91-98; DOI: https://doi.org/10.1124/jpet.105.087916
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    Involvement of Na+-Ca2+ Exchanger in Intracellular Ca2+ Increase and Neuronal Injury Induced by Polychlorinated Biphenyls in Human Neuroblastoma SH-SY5Y Cells
    Simona Magi, Pasqualina Castaldo, Giuseppina Carrieri, Antonella Scorziello, Gianfranco Di Renzo and Salvatore Amoroso
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 291-296; DOI: https://doi.org/10.1124/jpet.105.088948
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    The Effect of CYP2E1-Dependent Oxidant Stress on Activity of Proteasomes in HepG2 Cells
    Irina G. Kessova and Arthur I. Cederbaum
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 304-312; DOI: https://doi.org/10.1124/jpet.105.088047

Errata

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    Correction to “Resistance of Human Astrocytoma Cells to Apoptosis Induced by Mitochondria-Damaging Agents: Possible Implications for Anticancer Therapy”
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 475;
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    Correction to “Effect of 4-(5-Chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a Novel Opener of Large Conductance Ca2+-Activated K+ (Maxi-K) Channels on Normal and Stress-Aggravated Colonic Motility and Visceral Nociception”
    Journal of Pharmacology and Experimental Therapeutics October 2005, 315 (1) 476;
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Journal of Pharmacology and Experimental Therapeutics: 315 (1)
Journal of Pharmacology and Experimental Therapeutics
Vol. 315, Issue 1
1 Oct 2005
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  • PERSPECTIVES IN PHARMACOLOGY
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY
  • ENDOCRINE AND DIABETES
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
  • Errata
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  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
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