Journal of Pharmacology and Experimental Therapeutics: 314 (3)

September 01, 2005; Volume 314,Issue 3

PERSPECTIVES IN PHARMACOLOGY

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Can Claims, Misleading Information, and Manufacturing Issues Regarding Dietary Supplements Be Improved in the United States?
James E. Gibson and David A. Taylor

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 939-944; DOI: https://doi.org/10.1124/jpet.105.085712

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Identification of the Hepatic Efflux Transporters of Organic Anions Using Double-Transfected Madin-Darby Canine Kidney II Cells Expressing Human Organic Anion-Transporting Polypeptide 1B1 (OATP1B1)/Multidrug Resistance-Associated Protein 2, OATP1B1/Multidrug Resistance 1, and OATP1B1/Breast Cancer Resistance Protein
Soichiro Matsushima, Kazuya Maeda, Chihiro Kondo, Masaru Hirano, Makoto Sasaki, Hiroshi Suzuki and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1059-1067; DOI: https://doi.org/10.1124/jpet.105.085589
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Delineation of Human Peptide Transporter 1 (hPepT1)-Mediated Uptake and Transport of Substrates with Varying Transporter Affinities Utilizing Stably Transfected hPepT1/Madin-Darby Canine Kidney Clones and Caco-2 Cells
Rajinder K. Bhardwaj, Dea Herrera-Ruiz, Patrick J. Sinko, Olafur S. Gudmundsson and Gregory Knipp

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1093-1100; DOI: https://doi.org/10.1124/jpet.105.087148
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Development of Polyethylene Glycol-Conjugated Poly-S-Nitrosated Serum Albumin, a Novel S-Nitrosothiol for Prolonged Delivery of Nitric Oxide in the Blood Circulation in Vivo
Hidemasa Katsumi, Makiya Nishikawa, Fumiyoshi Yamashita and Mitsuru Hashida

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1117-1124; DOI: https://doi.org/10.1124/jpet.105.087429

BEHAVIORAL PHARMACOLOGY

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Morphine Side Effects in β-Arrestin 2 Knockout Mice
Kirsten M. Raehal, Julia K. L. Walker and Laura M. Bohn

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1195-1201; DOI: https://doi.org/10.1124/jpet.105.087254

CARDIOVASCULAR

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Mitogen-Activated Protein Kinase Phosphorylation in the Rostral Ventrolateral Medulla Plays a Key Role in Imidazoline (I₁)-Receptor-Mediated Hypotension
Jian Zhang and Abdel A. Abdel-Rahman

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 945-952; DOI: https://doi.org/10.1124/jpet.105.087510
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(+)-Norfenfluramine-Induced Arterial Contraction Is Not Dependent on Endogenous 5-Hydroxytryptamine or 5-Hydroxytryptamine Transporter
Wei Ni, Claudia S. Wilhelm, Michael Bader, Dennis L. Murphy, Keith Lookingland and Stephanie W. Watts

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 953-960; DOI: https://doi.org/10.1124/jpet.105.087080
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Effects of Cocaine on Nitric Oxide Production in Bovine Coronary Artery Endothelial Cells
Jiale He, Shumei Yang and Lubo Zhang

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 980-986; DOI: https://doi.org/10.1124/jpet.105.087452
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Mechanism of the Vascular Angiotensin II/α₂-Adrenoceptor Interaction
Edwin K. Jackson, Liping Gao and Chongxue Zhu

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1109-1116; DOI: https://doi.org/10.1124/jpet.105.086074
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Soy Isoflavones Improve Endothelial Function in Spontaneously Hypertensive Rats in an Estrogen-Independent Manner: Role of Nitric-Oxide Synthase, Superoxide, and Cyclooxygenase Metabolites
Rocío Vera, Milagros Galisteo, Inmaculada Concepción Villar, Manuel Sánchez, Antonio Zarzuelo, Francisco Pérez-Vizcaíno and Juan Duarte

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1300-1309; DOI: https://doi.org/10.1124/jpet.105.085530
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Mechanism of Fatty Acids Induced Suppression of Cardiovascular Reflexes in Rats
Hossam A. Shaltout and Abdel A. Abdel-Rahman

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1328-1337; DOI: https://doi.org/10.1124/jpet.105.086314
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Pretreatment with d-myo-Inositol Trisphosphate Reduces Infarct Size in Rabbit Hearts: Role of Inositol Trisphosphate Receptors and Gap Junctions in Triggering Protection
Karin Przyklenk, Michelle Maynard, Chad E. Darling and Peter Whittaker

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1386-1392; DOI: https://doi.org/10.1124/jpet.105.087742

CELLULAR AND MOLECULAR

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Modulation of Ca²⁺ Channels by Opioid Receptor-Like 1 Receptors Natively Expressed in Rat Stellate Ganglion Neurons Innervating Cardiac Muscle
Victor Ruiz-Velasco, Henry L. Puhl, Brad C. Fuller and Andrew D. Sumner

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 987-994; DOI: https://doi.org/10.1124/jpet.105.089284
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Delineation of Myotoxicity Induced by 3-Hydroxy-3-methylglutaryl CoA Reductase Inhibitors in Human Skeletal Muscle Cells
Julia Sacher, Lukas Weigl, Martin Werner, Csaba Szegedi and Martin Hohenegger

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1032-1041; DOI: https://doi.org/10.1124/jpet.105.086462
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Effects of Dinucleoside Polyphosphates on Trabecular Meshwork Cells and Aqueous Humor Outflow Facility
David Soto, Jesús Pintor, Assumpta Peral, Arcadi Gual and Xavier Gasull

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1042-1051; DOI: https://doi.org/10.1124/jpet.105.085274
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The Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Cross-Talk with Hepatic Nuclear Factor 4α to Synergistically Activate the Human CYP2C9 Promoter
Yuping Chen, Grace Kissling, Masahiko Negishi and Joyce A. Goldstein

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1125-1133; DOI: https://doi.org/10.1124/jpet.105.087072
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Inhibition of the A-Type K⁺ Channels of Dorsal Root Ganglion Neurons by the Long-Duration Anesthetic Butamben
D. L. B. Winkelman, C. L. Beck, D. L. Ypey and M. E. O'Leary

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1177-1186; DOI: https://doi.org/10.1124/jpet.105.087759
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Scalaradial Inhibition of Epidermal Growth Factor Receptor-Mediated Akt Phosphorylation Is Independent of Secretory Phospholipase A₂
Yili Xie, Lunhua Liu, Xiaochun Huang, Yuewei Guo and Liguang Lou

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1210-1217; DOI: https://doi.org/10.1124/jpet.105.086520
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Osthole-Mediated Cell Differentiation through Bone Morphogenetic Protein-2/p38 and Extracellular Signal-Regulated Kinase 1/2 Pathway in Human Osteoblast Cells
Po-Lin Kuo, Ya-Ling Hsu, Cheng-Hsiung Chang and Jiunn-Kae Chang

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1290-1299; DOI: https://doi.org/10.1124/jpet.105.085092
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Evaluation of Histamine H₁-, H₂-, and H₃-Receptor Ligands at the Human Histamine H₄ Receptor: Identification of 4-Methylhistamine as the First Potent and Selective H₄ Receptor Agonist
Herman D. Lim, Richard M. van Rijn, Ping Ling, Remko A. Bakker, Robin L. Thurmond and Rob Leurs

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1310-1321; DOI: https://doi.org/10.1124/jpet.105.087965

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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LY303511 (2-Piperazinyl-8-phenyl-4H-1-benzopyran-4-one) Acts via Phosphatidylinositol 3-Kinase-Independent Pathways to Inhibit Cell Proliferation via Mammalian Target of Rapamycin (mTOR)- and Non-mTOR-Dependent Mechanisms
Arnold S. Kristof, Gustavo Pacheco-Rodriguez, Bruno Schremmer and Joel Moss

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1134-1143; DOI: https://doi.org/10.1124/jpet.105.083550
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In Vitro Synergy and Enhanced Murine Brain Penetration of Saquinavir Coadministered with Mefloquine
Andrew Owen, Omar Janneh, Ruben C. Hartkoorn, Becky Chandler, Patrick G. Bray, Phillip Martin, Stephen A. Ward, C. Anthony Hart, Saye H. Khoo and David J. Back

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1202-1209; DOI: https://doi.org/10.1124/jpet.105.086272

ENDOCRINE AND REPRODUCTIVE

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Role of Protein Kinase C-Ras-MAPK p44/42 in Ethanol and Transforming Growth Factor-β3-Induced Basic Fibroblast Growth Factor Release from Folliculostellate Cells
Kirti Chaturvedi and Dipak K. Sarkar

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1346-1352; DOI: https://doi.org/10.1124/jpet.105.088302

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Inhibitors of Prostaglandin Transport and Metabolism Augment Protease-Activated Receptor-2-Mediated Increases in Prostaglandin E₂ Levels and Smooth Muscle Relaxation in Mouse Isolated Trachea
Peter J. Henry, Angela D'Aprile, Glenn Self, Tracy Hong and Tracy S. Mann

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 995-1001; DOI: https://doi.org/10.1124/jpet.105.086124
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Proliferative Signaling by Store-Operated Calcium Channels Opposes Colon Cancer Cell Cytostasis Induced by Bacterial Enterotoxins
Shiva Kazerounian, Giovanni M. Pitari, Fawad J. Shah, Glen S. Frick, Muniswamy Madesh, Inez Ruiz-Stewart, Stephanie Schulz, Gyorgy Hajnóczky and Scott A. Waldman

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1013-1022; DOI: https://doi.org/10.1124/jpet.105.089052
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Protection against Cisplatin-Induced Toxicities by N-Acetylcysteine and Sodium Thiosulfate as Assessed at the Molecular, Cellular, and in Vivo Levels
D. Thomas Dickey, Y. Jeffrey Wu, Leslie L. Muldoon and Edward A. Neuwelt

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1052-1058; DOI: https://doi.org/10.1124/jpet.105.087601
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A Novel, Long-Acting Agonist of Glucose-Dependent Insulinotropic Polypeptide Suitable for Once-Daily Administration in Type 2 Diabetes
Nigel Irwin, Brian D. Green, Mark H. Mooney, Brett Greer, Patrick Harriott, Clifford J. Bailey, Victor A. Gault, Finbarr P. M. O'Harte and Peter R. Flatt

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1187-1194; DOI: https://doi.org/10.1124/jpet.105.086082
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Substance P-Stimulated Interleukin-8 Expression in Human Colonic Epithelial Cells Involves Protein Kinase Cδ Activation
Hon-Wai Koon, Dezheng Zhao, Yanai Zhan, Simos Simeonidis, Mary P. Moyer and Charalabos Pothoulakis

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1393-1400; DOI: https://doi.org/10.1124/jpet.105.088013

INFLAMMATION AND IMMUNOPHARMACOLOGY

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Non-CpG-Containing Antisense 2′-Methoxyethyl Oligonucleotides Activate a Proinflammatory Response Independent of Toll-Like Receptor 9 or Myeloid Differentiation Factor 88
Joseph J. Senn, Sebastien Burel and Scott P. Henry

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 972-979; DOI: https://doi.org/10.1124/jpet.105.084004
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Oral Delivery and Gastrointestinal Absorption of Soluble Glucans Stimulate Increased Resistance to Infectious Challenge
Peter J. Rice, Elizabeth L. Adams, Tammy Ozment-Skelton, Andres J. Gonzalez, Matthew P. Goldman, Brent E. Lockhart, Luke A. Barker, Kevin F. Breuel, Warren K. DePonti, John H. Kalbfleisch, Harry E. Ensley, Gordon D. Brown, Siamon Gordon and David L. Williams

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1079-1086; DOI: https://doi.org/10.1124/jpet.105.085415
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Endogenous Aminopeptidase N Decreases the Potency of Peptide Agonists and Antagonists of the Kinin B₁ Receptors in the Rabbit Aorta
Jean-Philippe Fortin, Lajos Gera, Johanne Bouthillier, John M. Stewart, Albert Adam and François Marceau

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1169-1176; DOI: https://doi.org/10.1124/jpet.105.088799
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Neutrophil Adherence to Bladder Microvascular Endothelial Cells following Platelet-Activating Factor Acetylhydrolase Inhibition
Suzanne M. Vinson, Alice Rickard, Jan S. Ryerse and Jane McHowat

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1241-1247; DOI: https://doi.org/10.1124/jpet.105.085365

NEUROPHARMACOLOGY

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Pharmacological Implications of Two Distinct Mechanisms of Interaction of Memantine with N-Methyl-d-aspartate-Gated Channels
Huei-Sheng Vincent Chen and Stuart A. Lipton

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 961-971; DOI: https://doi.org/10.1124/jpet.105.085142
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(±)-3,4-Methylenedioxymethamphetamine Administration to Rats Does Not Decrease Levels of the Serotonin Transporter Protein or Alter Its Distribution between Endosomes and the Plasma Membrane
Xiaoying Wang, Michael H. Baumann, Heng Xu, Marisela Morales and Richard B. Rothman

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1002-1012; DOI: https://doi.org/10.1124/jpet.105.088476
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Divergent Pharmacological Activity of Novel Marine-Derived Excitatory Amino Acids on Glutamate Receptors
James M. Sanders, Koichi Ito, Luca Settimo, Olli T. Pentikäinen, Muneo Shoji, Makoto Sasaki, Mark S. Johnson, Ryuichi Sakai and Geoffrey T. Swanson

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1068-1078; DOI: https://doi.org/10.1124/jpet.105.086389
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Age-Dependent Methamphetamine-Induced Alterations in Vesicular Monoamine Transporter-2 Function: Implications for Neurotoxicity
Jannine G. Truong, Diana G. Wilkins, Jakub Baudys, Dennis J. Crouch, Kamisha L. Johnson-Davis, James W. Gibb, Glen R. Hanson and Annette E. Fleckenstein

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1087-1092; DOI: https://doi.org/10.1124/jpet.105.085951
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Antianalgesia: Stereoselective Action of dextro-Morphine over levo-Morphine on Glia in the Mouse Spinal Cord
Hsiang-En Wu, Jonathan Thompson, Han-Sen Sun, Maia Terashvili and Leon F. Tseng

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1101-1108; DOI: https://doi.org/10.1124/jpet.105.087130
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Contributions of the Mitogen-Activated Protein Kinase and Protein Kinase C Cascades in Spatial Learning and Memory Mediated by the Nucleus Accumbens
Lily Alvarez-Jaimes, Mara Feliciano-Rivera, Marjorie Centeno-González and Carmen S. Maldonado-Vlaar

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1144-1157; DOI: https://doi.org/10.1124/jpet.105.086140
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Pharmacodynamic and Pharmacokinetic Studies of Agmatine after Spinal Administration in the Mouse
John C. Roberts, Brent M. Grocholski, Kelley F. Kitto and Carolyn A. Fairbanks

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.105.086173
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The Role of Central and Peripheral μ Opioid Receptors in Inflammatory Pain and Edema: A Study Using Morphine and DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-3-yl]-acetic Acid)
Garth T. Whiteside, Jamie M. Boulet and Katharine Walker

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1234-1240; DOI: https://doi.org/10.1124/jpet.105.088351
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Sumanirole, a Highly Dopamine D₂-Selective Receptor Agonist: In Vitro and in Vivo Pharmacological Characterization and Efficacy in Animal Models of Parkinson's Disease
Robert B. McCall, Keith J. Lookingland, Paul J. Bédard and Rita M. Huff

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1248-1256; DOI: https://doi.org/10.1124/jpet.105.084202
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The Effects of a Selective Dopamine D₂ Receptor Agonist on Behavioral and Pathological Outcome in 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine-Treated Squirrel Monkeys
Diane T. Stephenson, Martin D. Meglasson, Mark A. Connell, Mary A. Childs, Eva Hajos-Korcsok and Marina E. Emborg

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1257-1266; DOI: https://doi.org/10.1124/jpet.105.087379
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Lecozotan (SRA-333): A Selective Serotonin 1A Receptor Antagonist That Enhances the Stimulated Release of Glutamate and Acetylcholine in the Hippocampus and Possesses Cognitive-Enhancing Properties
L. E. Schechter, D. L. Smith, S. Rosenzweig-Lipson, S. J. Sukoff, L. A. Dawson, K. Marquis, D. Jones, M. Piesla, T. Andree, S. Nawoschik, J. A. Harder, M. D. Womack, J. Buccafusco, A. V. Terry, B. Hoebel, P. Rada, M. Kelly, M. Abou-Gharbia, J. E. Barrett and W. Childers

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1274-1289; DOI: https://doi.org/10.1124/jpet.105.086363
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Hypocretin-1 (Orexin-A) Facilitates Inhibitory and Diminishes Excitatory Synaptic Pathways to Cardiac Vagal Neurons in the Nucleus Ambiguus
Olga Dergacheva, Xin Wang, Zheng-Gui Huang, Evguenia Bouairi, Christopher Stephens, Chistopher Gorini and David Mendelowitz

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1322-1327; DOI: https://doi.org/10.1124/jpet.105.086421
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Tertiapin-Q Blocks Recombinant and Native Large Conductance K⁺ Channels in a Use-Dependent Manner
Refik Kanjhan, Elizabeth J. Coulson, David J. Adams and Mark C. Bellingham

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1353-1361; DOI: https://doi.org/10.1124/jpet.105.085928
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Resting and Evoked Spinal Substance P Release during Chronic Intrathecal Morphine Infusion: Parallels with Tolerance and Dependence
Guibao Gu, Ichiro Kondo, Xiao-Ying Hua and Tony L. Yaksh

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1362-1369; DOI: https://doi.org/10.1124/jpet.105.087718
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Inhibition of High Voltage-Activated Calcium Channels by Spider Toxin PnTx3-6
Luciene B. Vieira, Christopher Kushmerick, Michael E. Hildebrand, Esperanza Garcia, Antony Stea, Marta N. Cordeiro, Michael Richardson, Marcus Vinicius Gomez and Terrance P. Snutch

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1370-1377; DOI: https://doi.org/10.1124/jpet.105.087023
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5-Iodoresiniferatoxin Evokes Hypothermia in Mice and Is a Partial Transient Receptor Potential Vanilloid 1 Agonist in Vitro
Isao Shimizu, Tohko Iida, Nobuhiko Horiuchi and Michael J. Caterina

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1378-1385; DOI: https://doi.org/10.1124/jpet.105.084277

TOXICOLOGY

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Coagulation-Mediated Hypoxia and Neutrophil-Dependent Hepatic Injury in Rats Given Lipopolysaccharide and Ranitidine
James P. Luyendyk, Patrick J. Shaw, Christopher D. Green, Jane F. Maddox, Patricia E. Ganey and Robert A. Roth

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1023-1031; DOI: https://doi.org/10.1124/jpet.105.087981
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Transport of N-Acetylcysteine S-Conjugates of Methylmercury in Madin-Darby Canine Kidney Cells Stably Transfected with Human Isoform of Organic Anion Transporter 1
Rudolfs K. Zalups and Sarfaraz Ahmad

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1158-1168; DOI: https://doi.org/10.1124/jpet.105.086645
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Hypersensitivity of HIV-1-Infected Cells to Reactive Sulfonamide Metabolites Correlated to Expression of the HIV-1 Viral Protein Tat
Jacqueline Arp, Michael J. Rieder, Brad Urquhart, David Freeman, M. Jane Tucker, Adriana Krizova, David Lehmann and Gregory A. Dekaban

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1218-1225; DOI: https://doi.org/10.1124/jpet.105.085050
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3,4-Methylenedioxymethamphetamine (Ecstasy) Activates Skeletal Muscle Nicotinic Acetylcholine Receptors
Werner Klingler, James J. A. Heffron, Karin Jurkat-Rott, Grainne O'Sullivan, Andreas Alt, Friedrich Schlesinger, Johannes Bufler and Frank Lehmann-Horn

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1267-1273; DOI: https://doi.org/10.1124/jpet.105.086629
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Up-Regulation of Uncoupling Protein 2 by Cyanide Is Linked with Cytotoxicity in Mesencephalic Cells
Krishnan Prabhakaran, Li Li, Edward M. Mills, Joseph L. Borowitz and Gary E. Isom

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1338-1345; DOI: https://doi.org/10.1124/jpet.105.088625

LETTERS TO THE EDITOR

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Comments on “Glycogen Synthase Kinase-3 Mediates Acetaminophen-Induced Apoptosis in Human Hepatoma Cells”
Hartmut Jaeschke

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1401-1402; DOI: https://doi.org/10.1124/jpet.105.089821
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Response: Comments on “Glycogen Synthase Kinase-3 Mediates Acetaminophen-Induced Apoptosis in Human Hepatoma Cells”
George E. N. Kass

Journal of Pharmacology and Experimental Therapeutics September 2005, 314 (3) 1403-1404; DOI: https://doi.org/10.1124/jpet.105.090548

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

LETTERS TO THE EDITOR

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