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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

A Farnesoid X Receptor-Small Heterodimer Partner Regulatory Cascade Modulates Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloprotease Expression in Hepatic Stellate Cells and Promotes Resolution of Liver Fibrosis

Stefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, Barbara Renga, Andrea Mencarelli, Luisa Riccardi, Stefano Orlandi, Mark Pruzanski, Antonio Morelli and Roberto Pellicciari
Journal of Pharmacology and Experimental Therapeutics August 2005, 314 (2) 584-595; DOI: https://doi.org/10.1124/jpet.105.084905

Article Information

vol. 314 no. 2 584-595
DOI 
https://doi.org/10.1124/jpet.105.084905
PubMed 
15860571
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received February 14, 2005
  • Accepted April 27, 2005
  • Published online July 15, 2005.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Stefano Fiorucci,
  2. Giovanni Rizzo,
  3. Elisabetta Antonelli,
  4. Barbara Renga,
  5. Andrea Mencarelli,
  6. Luisa Riccardi,
  7. Stefano Orlandi,
  8. Mark Pruzanski,
  9. Antonio Morelli and
  10. Roberto Pellicciari
  1. Dipartimento di Medicina Clinica e Sperimentale, Clinica di Gastroenterologia ed Endoscopia Digestiva, University of Perugia, Perugia, Italy (S.F., G.R., E.A., B.R., A.Me., L.R., S.O., A.Mo.); Dipartimento di Tecnologia del Farmaco, Faculty of Pharmacy, University of Perugia, Perugia, Italy (R.P.); and Intercept Pharmaceuticals, New York, New York (M.P.)
  1. Address correspondence to:
    Dr. Stefano Fiorucci, University of Perugia, Policlinico Monteluce, Via E. Dal Pozzo, 06122 Perugia, Italy. E-mail: fiorucci{at}unipg.it
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Research ArticleGASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

A Farnesoid X Receptor-Small Heterodimer Partner Regulatory Cascade Modulates Tissue Metalloproteinase Inhibitor-1 and Matrix Metalloprotease Expression in Hepatic Stellate Cells and Promotes Resolution of Liver Fibrosis

Stefano Fiorucci, Giovanni Rizzo, Elisabetta Antonelli, Barbara Renga, Andrea Mencarelli, Luisa Riccardi, Stefano Orlandi, Mark Pruzanski, Antonio Morelli and Roberto Pellicciari
Journal of Pharmacology and Experimental Therapeutics August 1, 2005, 314 (2) 584-595; DOI: https://doi.org/10.1124/jpet.105.084905
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