Journal of Pharmacology and Experimental Therapeutics: 313 (2)

May 01, 2005; Volume 313,Issue 2

PERSPECTIVES IN PHARMACOLOGY

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Altered Neurotrophism in Diabetic Neuropathy: Spelunking the Caves of Peripheral Nerve
Rick T. Dobrowsky, Shefali Rouen and Cuijuan Yu

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 485-491; DOI: https://doi.org/10.1124/jpet.104.079921

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Selective Inhibition of Dog Hepatic CYP2B11 and CYP3A12
Ping Lu, Suresh B. Singh, Brian A. Carr, Yulin Fang, Cathie Dong Xiang, Thomas H. Rushmore, A. David Rodrigues and Magang Shou

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 518-528; DOI: https://doi.org/10.1124/jpet.104.077651
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Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2
Katrin Letschert, Masaharu Komatsu, Johanna Hummel-Eisenbeiss and Dietrich Keppler

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 549-556; DOI: https://doi.org/10.1124/jpet.104.081224
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Transport of the Natural Sweetener Stevioside and Its Aglycone Steviol by Human Organic Anion Transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8)
Chutima Srimaroeng, Varanuj Chatsudthipong, Amy G. Aslamkhan and John B. Pritchard

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 621-628; DOI: https://doi.org/10.1124/jpet.104.080366
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Mechanistic Pharmacokinetic and Pharmacodynamic Modeling of CHF3381 (2-[(2,3-Dihydro-1H-inden-2-yl)amino]acetamide Monohydrochloride), a Novel N-Methyl-d-aspartate Antagonist and Monoamine Oxidase-A Inhibitor in Healthy Subjects
Chantal Csajka, Bruno P. Imbimbo, Annalisa Piccinno, Philippe Dostert and Davide Verotta

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 647-657; DOI: https://doi.org/10.1124/jpet.104.080457
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Dose-Related Distribution of Codeine, Cocaine, and Metabolites into Human Hair following Controlled Oral Codeine and Subcutaneous Cocaine Administration
Karl B. Scheidweiler, Edward J. Cone, Eric T. Moolchan and Marilyn A. Huestis

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 909-915; DOI: https://doi.org/10.1124/jpet.104.082388

BEHAVIORAL PHARMACOLOGY

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Effects of 4′-Chloro-3α-(diphenylmethoxy)-tropane on Mesostriatal, Mesocortical, and Mesolimbic Dopamine Transmission: Comparison with Effects of Cocaine
Gianluigi Tanda, Aaron Ebbs, Amy H. Newman and Jonathan L. Katz

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 613-620; DOI: https://doi.org/10.1124/jpet.104.080465
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Contribution of α₁GABA_A and α₅GABA_A Receptor Subtypes to the Discriminative Stimulus Effects of Ethanol in Squirrel Monkeys
Donna M. Platt, Annemarie Duggan, Roger D. Spealman, James M. Cook, Xiaoyan Li, Wenyuan Yin and James K. Rowlett

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 658-667; DOI: https://doi.org/10.1124/jpet.104.080275
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Relationship between the Serotonergic Activity and Reinforcing Effects of a Series of Amphetamine Analogs
S. Wee, K. G. Anderson, M. H. Baumann, R. B. Rothman, B. E. Blough and W. L. Woolverton

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 848-854; DOI: https://doi.org/10.1124/jpet.104.080101
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Acetazolamide, a Carbonic Anhydrase Inhibitor, Reverses Inflammation-Induced Thermal Hyperalgesia in Rats
Rajan Radhakrishnan and Kathleen A. Sluka

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 921-927; DOI: https://doi.org/10.1124/jpet.104.082776

CARDIOVASCULAR

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Cilostazol Reduces Atherosclerosis by Inhibition of Superoxide and Tumor Necrosis Factor-α Formation in Low-Density Lipoprotein Receptor-Null Mice Fed High Cholesterol
Jeong Hyun Lee, Goo Taeg Oh, So Youn Park, Jae-Hoon Choi, Jong-Gil Park, Chi Dae Kim, Won Suk Lee, Byung Yong Rhim, Yung Woo Shin and Ki Whan Hong

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 502-509; DOI: https://doi.org/10.1124/jpet.104.079780
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Functional Interactions between 5-Hydroxytryptamine Receptors and the Serotonin Transporter in Pulmonary Arteries
Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar and Margaret R. MacLean

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 539-548; DOI: https://doi.org/10.1124/jpet.104.081182
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Rosuvastatin Attenuates Monocyte-Endothelial Cell Interactions and Vascular Free Radical Production in Hypercholesterolemic Mice
Wei Li, Tomoko Asagami, Hidetsugu Matsushita, Keun-Ho Lee and Philip S. Tsao

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 557-562; DOI: https://doi.org/10.1124/jpet.104.080002
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Ectonucleoside Triphosphate Diphosphohydrolase1/CD39, Localized in Neurons of Human and Porcine Heart, Modulates ATP-Induced Norepinephrine Exocytosis
Takuji Machida, Paul M. Heerdt, Alicia C. Reid, Ulrich Schäfer, Randi B. Silver, M. Johan Broekman, Aaron J. Marcus and Roberto Levi

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 570-577; DOI: https://doi.org/10.1124/jpet.104.081240
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Peroxisome Proliferator-Activated Receptor Agonists Modulate Heart Function in Transgenic Mice with Lipotoxic Cardiomyopathy
Reeba K. Vikramadithyan, Kumiko Hirata, Hiroaki Yagyu, Yunying Hu, Ayanna Augustus, Shunichi Homma and Ira J. Goldberg

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 586-593; DOI: https://doi.org/10.1124/jpet.104.080259
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Down-Regulation of Na⁺ Pump α₂ Isoform in Isoprenaline-Induced Cardiac Hypertrophy in Rat: Evidence for Increased Receptor Binding Affinity but Reduced Inotropic Potency of Digoxin
Myoungki Baek and Michael Weiss

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 731-739; DOI: https://doi.org/10.1124/jpet.104.078345
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Mechanism of Myricetin Stimulation of Vascular L-type Ca²⁺ Current
Fabio Fusi, Giampietro Sgaragli and Simona Saponara

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 790-797; DOI: https://doi.org/10.1124/jpet.104.080135
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Pretreatment with Pinacidil Promotes Arrhythmias in an Isolated Tissue Model of Cardiac Ischemia and Reperfusion
Gregory R. Ferrier and Susan E. Howlett

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 823-830; DOI: https://doi.org/10.1124/jpet.104.081349
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Inhibition of Human ether-a-go-go-Related Gene K⁺ Channel and I_Kr of Guinea Pig Cardiomyocytes by Antipsychotic Drug Trifluoperazine
Se-Young Choi, Young-Sang Koh and Su-Hyun Jo

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 888-895; DOI: https://doi.org/10.1124/jpet.104.080853
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The Cardioprotective Effects of Preconditioning with Endotoxin, but Not Ischemia, Are Abolished by a Peroxisome Proliferator-Activated Receptor-γ Antagonist
Ahila Sivarajah, Michelle C. McDonald and Christoph Thiemermann

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 896-901; DOI: https://doi.org/10.1124/jpet.104.080598

CELLULAR AND MOLECULAR

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Multiple Binding Sites Revealed by Interaction of Relaxin Family Peptides with Native and Chimeric Relaxin Family Peptide Receptors 1 and 2 (LGR7 and LGR8)
Michelle L. Halls, Courtney P. Bond, Satoko Sudo, Jin Kumagai, Tania Ferraro, Sharon Layfield, Ross A. D. Bathgate and Roger J. Summers

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 677-687; DOI: https://doi.org/10.1124/jpet.104.080655
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Asparagine, Valine, and Threonine in the Third Extracellular Loop of Muscarinic Receptor Have Essential Roles in the Positive Cooperativity of Strychnine-Like Allosteric Modulators
J. Jakubík, A. Krejčí and V. Doležal

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 688-696; DOI: https://doi.org/10.1124/jpet.104.080358
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The Antiepileptic Drug Levetiracetam Decreases the Inositol 1,4,5-Trisphosphate-Dependent [Ca²⁺]_i Increase Induced by ATP and Bradykinin in PC12 Cells
Mauro Cataldi, Vincenzo Lariccia, Agnese Secondo, Gianfranco di Renzo and Lucio Annunziato

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 720-730; DOI: https://doi.org/10.1124/jpet.104.079327
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Functional Activity of the M₂ and M₄ Receptor Subtypes in the Spinal Cord Studied with Muscarinic Acetylcholine Receptor Knockout Mice
Shao-Rui Chen, Jürgen Wess and Hui-Lin Pan

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 765-770; DOI: https://doi.org/10.1124/jpet.104.082537
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RH1 Induces Cellular Damage in an NAD(P)H:Quinone Oxidoreductase 1-Dependent Manner: Relationship between DNA Cross-linking, Cell Cycle Perturbations, and Apoptosis
Donna L. Dehn, Salmaan H. Inayat-Hussain and David Ross

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 771-779; DOI: https://doi.org/10.1124/jpet.104.081380
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Transcriptional Regulation of the Human CYP2A6 Gene
Marià Pitarque, Cristina Rodríguez-Antona, Mikael Oscarson and Magnus Ingelman-Sundberg

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 814-822; DOI: https://doi.org/10.1124/jpet.104.081570
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Arsenite Delays Progression through Each Cell Cycle Phase and Induces Apoptosis following G₂/M Arrest in U937 Myeloid Leukemia Cells
Geniece McCollum, Peter C. Keng, J. Christopher States and Michael J. McCabe

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 877-887; DOI: https://doi.org/10.1124/jpet.104.080713

ENDOCRINE AND REPRODUCTIVE

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Endocrinological Properties of Two Novel Nonsteroidal Progesterone Receptor Modulators, CP8816 and CP8863
Yasushi Kurata, Yuji Tabata, Rie Shinei, Yumiko Iizuka, Naomi Takei Masuda, Ken-ichi Kurihara, Tsuneo Okonogi and Shigeru Hoshiko

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 916-920; DOI: https://doi.org/10.1124/jpet.104.074146

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Protective Effects of 6-Ethyl Chenodeoxycholic Acid, a Farnesoid X Receptor Ligand, in Estrogen-Induced Cholestasis
Stefano Fiorucci, Carlo Clerici, Elisabetta Antonelli, Stefano Orlandi, Bryan Goodwin, Bahman M. Sadeghpour, Giuseppe Sabatino, Giuseppe Russo, Danilo Castellani, Timothy M. Willson, Mark Pruzanski, Roberto Pellicciari and Antonio Morelli

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 604-612; DOI: https://doi.org/10.1124/jpet.104.079665
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Mechanism of Bradykinin-Induced Ca²⁺ Mobilization in Murine Proximal Tubule Epithelial Cells
Manish M. Tiwari, Paul L. Prather and Philip R. Mayeux

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 798-805; DOI: https://doi.org/10.1124/jpet.104.080408
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Effect of 4-(5-Chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a Novel Opener of Large Conductance Ca²+-Activated K⁺ (Maxi-K) Channels on Normal and Stress-Aggravated Colonic Motility and Visceral Nociception
Digavalli V. Sivarao, Kimberly Newberry, Shaun Langdon, Alicia V. Lee, Piyasena Hewawasam, Mary Jane Plym, Laura Signor, Robert Myers and Nicholas J. Lodge

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 840-847; DOI: https://doi.org/10.1124/jpet.104.079285

INFLAMMATION AND IMMUNOPHARMACOLOGY

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AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression
Charles Kunsch, Jayraz Luchoomun, Xi-lin Chen, Geraldine L. Dodd, Kanika S. Karu, Charles Q. Meng, Elaine M. Marino, Lyn K. Olliff, J. Daniel Piper, Fei-Hua Qiu, James A. Sikorski, Patricia K. Somers, Ki-Ling Suen, Suzanne Thomas, Anne M. Whalen, Martin A. Wasserman and Cynthia L. Sundell

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 492-501; DOI: https://doi.org/10.1124/jpet.104.080804
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Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and the Development of Bleomycin-Induced Lung Injury
Tiziana Genovese, Emanuela Mazzon, Rosanna Di Paola, Carmelo Muià, Michael D. Threadgill, Achille P. Caputi, Christoph Thiemermann and Salvatore Cuzzocrea

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 529-538; DOI: https://doi.org/10.1124/jpet.104.080705
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Formation, Distribution, and Elimination of Infliximab and Anti-Infliximab Immune Complexes in Cynomolgus Monkeys
Jeannie R. Rojas, Ronald P. Taylor, Mark R. Cunningham, Thomas J. Rutkoski, Joseph Vennarini, Haishan Jang, Martin A. Graham, Karel Geboes, Serge D. Rousselle and Carrie L. Wagner

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 578-585; DOI: https://doi.org/10.1124/jpet.104.079277
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Cloning and Characterization of Cyclooxygenase-1b (Putative Cyclooxygenase-3) in Rat
James A. Snipes, Bela Kis, Gregory S. Shelness, James A. Hewett and David W. Busija

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 668-676; DOI: https://doi.org/10.1124/jpet.104.079533
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Inhibition of S-Adenosyl-l-homocysteine Hydrolase Induces Immunosuppression
Qing-Li Wu, Yun-Feng Fu, Wen-Liang Zhou, Jun-Xia Wang, Yong-Hong Feng, Jing Liu, Jian-Yi Xu, Pei-Lan He, Ru Zhou, Wei Tang, Gui-Feng Wang, Yu Zhou, Yi-Fu Yang, Jian Ding, Xiao-Yu Li, Xiao-Ru Chen, Chong Yuan, Brian R. Lawson and Jian-Ping Zuo

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 705-711; DOI: https://doi.org/10.1124/jpet.104.080416

NEUROPHARMACOLOGY

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Time-Dependent Changes in Receptor/G-Protein Coupling in Rat Brain following Chronic Monoamine Transporter Blockade
Kerry A. O'Connor, Linda J. Porrino, Huw M. L. Davies and Steven R. Childers

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 510-517; DOI: https://doi.org/10.1124/jpet.104.078451
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Molecular Determinants of Glycine-Independent Desensitization of NR1/NR2A Receptors
Bo Hu and Fang Zheng

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 563-569; DOI: https://doi.org/10.1124/jpet.104.080168
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Clozapine Potentiation of N-Methyl-d-aspartate Receptor Currents in the Nucleus Accumbens: Role of NR2B and Protein Kinase A/Src Kinases
Marion Wittmann, Michael J. Marino, Darrell A. Henze, Guy R. Seabrook and P. Jeffrey Conn

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 594-603; DOI: https://doi.org/10.1124/jpet.104.080200
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M₂, M₃, and M₄ Receptor Subtypes Contribute to Muscarinic Potentiation of GABAergic Inputs to Spinal Dorsal Horn Neurons
Hong-Mei Zhang, De-Pei Li, Shao-Rui Chen and Hui-Lin Pan

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 697-704; DOI: https://doi.org/10.1124/jpet.104.079939
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Improved Brain Uptake and Pharmacological Activity Profile of Morphine-6-Glucuronide Using a Peptide Vector-Mediated Strategy
Jamal Temsamani, Cécile Bonnafous, Christophe Rousselle, Yannik Fraisse, Philippe Clair, Luc-André Granier, Anthony R. Rees, Michel Kaczorek and Jean-Michel Scherrmann

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 712-719; DOI: https://doi.org/10.1124/jpet.104.081000
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Nicotinic Receptor Subtypes in Rat Hippocampal Slices Are Differentially Sensitive to Desensitization and Early in Vivo Functional Up-Regulation by Nicotine and to Block by Bupropion
Manickavasagom Alkondon and Edson X. Albuquerque

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 740-750; DOI: https://doi.org/10.1124/jpet.104.081232
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The Nonthiazolidinedione Tyrosine-Based Peroxisome Proliferator-Activated Receptor γ Ligand GW7845 Induces Apoptosis and Limits Migration and Invasion of Rat and Human Glioma Cells
Christian Grommes, Gary E. Landreth, Uwe Schlegel and Michael T. Heneka

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 806-813; DOI: https://doi.org/10.1124/jpet.104.078972
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Anxiolytic- and Antidepressant-Like Profile of ATC0065 and ATC0175: Nonpeptidic and Orally Active Melanin-Concentrating Hormone Receptor 1 Antagonists
Shigeyuki Chaki, Takeo Funakoshi, Shiho Hirota-Okuno, Mariko Nishiguchi, Toshiharu Shimazaki, Michihiko Iijima, Andrew J. Grottick, Kosuke Kanuma, Katsunori Omodera, Yoshinori Sekiguchi, Shigeru Okuyama, Thuy-Anh Tran, Graeme Semple and William Thomsen

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 831-839; DOI: https://doi.org/10.1124/jpet.104.081711
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WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Anorectic Activity
John Dunlop, Annmarie L. Sabb, Hossein Mazandarani, Jean Zhang, Sachin Kalgaonker, Eugenia Shukhina, Stacey Sukoff, Robert L. Vogel, Gary Stack, Lee Schechter, Boyd L. Harrison and Sharon Rosenzweig-Lipson

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 862-869; DOI: https://doi.org/10.1124/jpet.104.075382
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Cyclooxygenase-2 Is an Obligatory Factor in Methamphetamine-Induced Neurotoxicity
David M. Thomas and Donald M. Kuhn

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 870-876; DOI: https://doi.org/10.1124/jpet.104.080242
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Quantitative Measurement of Changes in Amyloid-β(40) in the Rat Brain and Cerebrospinal Fluid following Treatment with the γ-Secretase Inhibitor LY-411575 [N²-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N¹-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-l-alaninamide]
Jonathan D. Best, Mark T. Jay, Franklin Otu, Jerome Ma, Alan Nadin, Semantha Ellis, Huw D. Lewis, Christine Pattison, Michael Reilly, Timothy Harrison, Mark S. Shearman, Toni L. Williamson and John R. Atack

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 902-908; DOI: https://doi.org/10.1124/jpet.104.081174

TOXICOLOGY

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The Role of Mitochondrial Uncoupling in 3,4-Methylenedioxymethamphetamine-Mediated Skeletal Muscle Hyperthermia and Rhabdomyolysis
Daniel E. Rusyniak, Stephany L. Tandy, S. K. Hekmatyar, Edward Mills, David J. Smith, Navin Bansal, Darcy MacLellan, Mary-Ellen Harper and Jon E. Sprague

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 629-639; DOI: https://doi.org/10.1124/jpet.104.079236
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Specific Antibody Modulates Absorptive Transport and Metabolic Activation of Benzo[a]pyrene across Caco-2 Monolayers
Stefan S. De Buck, Patrick Augustijns and Claude P. Muller

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 640-646; DOI: https://doi.org/10.1124/jpet.104.081034
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Methylmercury Induces a Spontaneous, Transient Slow Inward Chloride Current in Purkinje Cells of Rat Cerebellar Slices
Yukun Yuan and William D. Atchison

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 751-764; DOI: https://doi.org/10.1124/jpet.104.080721
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Glycogen Synthase Kinase-3 Mediates Acetaminophen-Induced Apoptosis in Human Hepatoma Cells
Patricia Macanas-Pirard, Nik-Soriani Yaacob, Pauline C. Lee, Julie C. Holder, Richard H. Hinton and George E. N. Kass

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 780-789; DOI: https://doi.org/10.1124/jpet.104.081364
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Mutagenic Effects of 4-Hydroxynonenal Triacetate, a Chemically Protected Form of the Lipid Peroxidation Product 4-Hydroxynonenal, as Assayed in L5178Y/Tk⁺/– Mouse Lymphoma Cells
Sharda P. Singh, Tao Chen, Ling Chen, Nan Mei, Eric McLain, Victor Samokyszyn, John J. Thaden, Martha M. Moore and Piotr Zimniak

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 855-861; DOI: https://doi.org/10.1124/jpet.104.080754

LETTERS TO THE EDITOR

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Comments on “Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-d-aspartate Receptors in Rat Hippocampal Neurons”
Pradeep Banerjee, Gary Samoriski and Sandeep Gupta

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 928-929; DOI: https://doi.org/10.1124/jpet.104.081976
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Response: Comments on “Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-d-aspartate Receptors in Rat Hippocampal Neurons”
Yasco Aracava, Edna F. R. Pereira, Alfred Maelicke and Edson X. Albuquerque

Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 930-933; DOI: https://doi.org/10.1124/jpet.104.082222

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

LETTERS TO THE EDITOR

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