Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Journal of Pharmacology and Experimental Therapeutics
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Journal of Pharmacology and Experimental Therapeutics

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit jpet on Facebook
  • Follow jpet on Twitter
  • Follow jpet on LinkedIn

Table of Contents

May 01, 2005; Volume 313,Issue 2

PERSPECTIVES IN PHARMACOLOGY

  • You have access
    Altered Neurotrophism in Diabetic Neuropathy: Spelunking the Caves of Peripheral Nerve
    Rick T. Dobrowsky, Shefali Rouen and Cuijuan Yu
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 485-491; DOI: https://doi.org/10.1124/jpet.104.079921

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

  • You have access
    Selective Inhibition of Dog Hepatic CYP2B11 and CYP3A12
    Ping Lu, Suresh B. Singh, Brian A. Carr, Yulin Fang, Cathie Dong Xiang, Thomas H. Rushmore, A. David Rodrigues and Magang Shou
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 518-528; DOI: https://doi.org/10.1124/jpet.104.077651
  • You have access
    Vectorial Transport of the Peptide CCK-8 by Double-Transfected MDCKII Cells Stably Expressing the Organic Anion Transporter OATP1B3 (OATP8) and the Export Pump ABCC2
    Katrin Letschert, Masaharu Komatsu, Johanna Hummel-Eisenbeiss and Dietrich Keppler
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 549-556; DOI: https://doi.org/10.1124/jpet.104.081224
  • You have access
    Transport of the Natural Sweetener Stevioside and Its Aglycone Steviol by Human Organic Anion Transporter (hOAT1; SLC22A6) and hOAT3 (SLC22A8)
    Chutima Srimaroeng, Varanuj Chatsudthipong, Amy G. Aslamkhan and John B. Pritchard
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 621-628; DOI: https://doi.org/10.1124/jpet.104.080366
  • You have access
    Mechanistic Pharmacokinetic and Pharmacodynamic Modeling of CHF3381 (2-[(2,3-Dihydro-1H-inden-2-yl)amino]acetamide Monohydrochloride), a Novel N-Methyl-d-aspartate Antagonist and Monoamine Oxidase-A Inhibitor in Healthy Subjects
    Chantal Csajka, Bruno P. Imbimbo, Annalisa Piccinno, Philippe Dostert and Davide Verotta
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 647-657; DOI: https://doi.org/10.1124/jpet.104.080457
  • You have access
    Dose-Related Distribution of Codeine, Cocaine, and Metabolites into Human Hair following Controlled Oral Codeine and Subcutaneous Cocaine Administration
    Karl B. Scheidweiler, Edward J. Cone, Eric T. Moolchan and Marilyn A. Huestis
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 909-915; DOI: https://doi.org/10.1124/jpet.104.082388

BEHAVIORAL PHARMACOLOGY

  • You have access
    Effects of 4′-Chloro-3α-(diphenylmethoxy)-tropane on Mesostriatal, Mesocortical, and Mesolimbic Dopamine Transmission: Comparison with Effects of Cocaine
    Gianluigi Tanda, Aaron Ebbs, Amy H. Newman and Jonathan L. Katz
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 613-620; DOI: https://doi.org/10.1124/jpet.104.080465
  • You have access
    Contribution of α1GABAA and α5GABAA Receptor Subtypes to the Discriminative Stimulus Effects of Ethanol in Squirrel Monkeys
    Donna M. Platt, Annemarie Duggan, Roger D. Spealman, James M. Cook, Xiaoyan Li, Wenyuan Yin and James K. Rowlett
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 658-667; DOI: https://doi.org/10.1124/jpet.104.080275
  • You have access
    Relationship between the Serotonergic Activity and Reinforcing Effects of a Series of Amphetamine Analogs
    S. Wee, K. G. Anderson, M. H. Baumann, R. B. Rothman, B. E. Blough and W. L. Woolverton
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 848-854; DOI: https://doi.org/10.1124/jpet.104.080101
  • You have access
    Acetazolamide, a Carbonic Anhydrase Inhibitor, Reverses Inflammation-Induced Thermal Hyperalgesia in Rats
    Rajan Radhakrishnan and Kathleen A. Sluka
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 921-927; DOI: https://doi.org/10.1124/jpet.104.082776

CARDIOVASCULAR

  • You have access
    Cilostazol Reduces Atherosclerosis by Inhibition of Superoxide and Tumor Necrosis Factor-α Formation in Low-Density Lipoprotein Receptor-Null Mice Fed High Cholesterol
    Jeong Hyun Lee, Goo Taeg Oh, So Youn Park, Jae-Hoon Choi, Jong-Gil Park, Chi Dae Kim, Won Suk Lee, Byung Yong Rhim, Yung Woo Shin and Ki Whan Hong
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 502-509; DOI: https://doi.org/10.1124/jpet.104.079780
  • You have access
    Functional Interactions between 5-Hydroxytryptamine Receptors and the Serotonin Transporter in Pulmonary Arteries
    Ian Morecroft, Lynn Loughlin, Margaret Nilsen, Janet Colston, Yvonne Dempsie, John Sheward, Anthony Harmar and Margaret R. MacLean
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 539-548; DOI: https://doi.org/10.1124/jpet.104.081182
  • You have access
    Rosuvastatin Attenuates Monocyte-Endothelial Cell Interactions and Vascular Free Radical Production in Hypercholesterolemic Mice
    Wei Li, Tomoko Asagami, Hidetsugu Matsushita, Keun-Ho Lee and Philip S. Tsao
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 557-562; DOI: https://doi.org/10.1124/jpet.104.080002
  • You have access
    Ectonucleoside Triphosphate Diphosphohydrolase1/CD39, Localized in Neurons of Human and Porcine Heart, Modulates ATP-Induced Norepinephrine Exocytosis
    Takuji Machida, Paul M. Heerdt, Alicia C. Reid, Ulrich Schäfer, Randi B. Silver, M. Johan Broekman, Aaron J. Marcus and Roberto Levi
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 570-577; DOI: https://doi.org/10.1124/jpet.104.081240
  • You have access
    Peroxisome Proliferator-Activated Receptor Agonists Modulate Heart Function in Transgenic Mice with Lipotoxic Cardiomyopathy
    Reeba K. Vikramadithyan, Kumiko Hirata, Hiroaki Yagyu, Yunying Hu, Ayanna Augustus, Shunichi Homma and Ira J. Goldberg
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 586-593; DOI: https://doi.org/10.1124/jpet.104.080259
  • You have access
    Down-Regulation of Na+ Pump α2 Isoform in Isoprenaline-Induced Cardiac Hypertrophy in Rat: Evidence for Increased Receptor Binding Affinity but Reduced Inotropic Potency of Digoxin
    Myoungki Baek and Michael Weiss
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 731-739; DOI: https://doi.org/10.1124/jpet.104.078345
  • You have access
    Mechanism of Myricetin Stimulation of Vascular L-type Ca2+ Current
    Fabio Fusi, Giampietro Sgaragli and Simona Saponara
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 790-797; DOI: https://doi.org/10.1124/jpet.104.080135
  • You have access
    Pretreatment with Pinacidil Promotes Arrhythmias in an Isolated Tissue Model of Cardiac Ischemia and Reperfusion
    Gregory R. Ferrier and Susan E. Howlett
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 823-830; DOI: https://doi.org/10.1124/jpet.104.081349
  • You have access
    Inhibition of Human ether-a-go-go-Related Gene K+ Channel and IKr of Guinea Pig Cardiomyocytes by Antipsychotic Drug Trifluoperazine
    Se-Young Choi, Young-Sang Koh and Su-Hyun Jo
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 888-895; DOI: https://doi.org/10.1124/jpet.104.080853
  • You have access
    The Cardioprotective Effects of Preconditioning with Endotoxin, but Not Ischemia, Are Abolished by a Peroxisome Proliferator-Activated Receptor-γ Antagonist
    Ahila Sivarajah, Michelle C. McDonald and Christoph Thiemermann
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 896-901; DOI: https://doi.org/10.1124/jpet.104.080598

CELLULAR AND MOLECULAR

  • You have access
    Multiple Binding Sites Revealed by Interaction of Relaxin Family Peptides with Native and Chimeric Relaxin Family Peptide Receptors 1 and 2 (LGR7 and LGR8)
    Michelle L. Halls, Courtney P. Bond, Satoko Sudo, Jin Kumagai, Tania Ferraro, Sharon Layfield, Ross A. D. Bathgate and Roger J. Summers
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 677-687; DOI: https://doi.org/10.1124/jpet.104.080655
  • You have access
    Asparagine, Valine, and Threonine in the Third Extracellular Loop of Muscarinic Receptor Have Essential Roles in the Positive Cooperativity of Strychnine-Like Allosteric Modulators
    J. Jakubík, A. Krejčí and V. Doležal
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 688-696; DOI: https://doi.org/10.1124/jpet.104.080358
  • You have access
    The Antiepileptic Drug Levetiracetam Decreases the Inositol 1,4,5-Trisphosphate-Dependent [Ca2+]i Increase Induced by ATP and Bradykinin in PC12 Cells
    Mauro Cataldi, Vincenzo Lariccia, Agnese Secondo, Gianfranco di Renzo and Lucio Annunziato
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 720-730; DOI: https://doi.org/10.1124/jpet.104.079327
  • You have access
    Functional Activity of the M2 and M4 Receptor Subtypes in the Spinal Cord Studied with Muscarinic Acetylcholine Receptor Knockout Mice
    Shao-Rui Chen, Jürgen Wess and Hui-Lin Pan
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 765-770; DOI: https://doi.org/10.1124/jpet.104.082537
  • You have access
    RH1 Induces Cellular Damage in an NAD(P)H:Quinone Oxidoreductase 1-Dependent Manner: Relationship between DNA Cross-linking, Cell Cycle Perturbations, and Apoptosis
    Donna L. Dehn, Salmaan H. Inayat-Hussain and David Ross
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 771-779; DOI: https://doi.org/10.1124/jpet.104.081380
  • You have access
    Transcriptional Regulation of the Human CYP2A6 Gene
    Marià Pitarque, Cristina Rodríguez-Antona, Mikael Oscarson and Magnus Ingelman-Sundberg
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 814-822; DOI: https://doi.org/10.1124/jpet.104.081570
  • You have access
    Arsenite Delays Progression through Each Cell Cycle Phase and Induces Apoptosis following G2/M Arrest in U937 Myeloid Leukemia Cells
    Geniece McCollum, Peter C. Keng, J. Christopher States and Michael J. McCabe
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 877-887; DOI: https://doi.org/10.1124/jpet.104.080713

ENDOCRINE AND REPRODUCTIVE

  • You have access
    Endocrinological Properties of Two Novel Nonsteroidal Progesterone Receptor Modulators, CP8816 and CP8863
    Yasushi Kurata, Yuji Tabata, Rie Shinei, Yumiko Iizuka, Naomi Takei Masuda, Ken-ichi Kurihara, Tsuneo Okonogi and Shigeru Hoshiko
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 916-920; DOI: https://doi.org/10.1124/jpet.104.074146

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

  • You have access
    Protective Effects of 6-Ethyl Chenodeoxycholic Acid, a Farnesoid X Receptor Ligand, in Estrogen-Induced Cholestasis
    Stefano Fiorucci, Carlo Clerici, Elisabetta Antonelli, Stefano Orlandi, Bryan Goodwin, Bahman M. Sadeghpour, Giuseppe Sabatino, Giuseppe Russo, Danilo Castellani, Timothy M. Willson, Mark Pruzanski, Roberto Pellicciari and Antonio Morelli
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 604-612; DOI: https://doi.org/10.1124/jpet.104.079665
  • You have access
    Mechanism of Bradykinin-Induced Ca2+ Mobilization in Murine Proximal Tubule Epithelial Cells
    Manish M. Tiwari, Paul L. Prather and Philip R. Mayeux
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 798-805; DOI: https://doi.org/10.1124/jpet.104.080408
  • You have access
    Effect of 4-(5-Chloro-2-hydroxyphenyl)-3-(2-hydroxyethyl)-6-(trifluoromethyl)-quinolin-2(1H)-one (BMS-223131), a Novel Opener of Large Conductance Ca2+-Activated K+ (Maxi-K) Channels on Normal and Stress-Aggravated Colonic Motility and Visceral Nociception
    Digavalli V. Sivarao, Kimberly Newberry, Shaun Langdon, Alicia V. Lee, Piyasena Hewawasam, Mary Jane Plym, Laura Signor, Robert Myers and Nicholas J. Lodge
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 840-847; DOI: https://doi.org/10.1124/jpet.104.079285

INFLAMMATION AND IMMUNOPHARMACOLOGY

  • You have access
    AGIX-4207 [2-[4-[[1-[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]thio]-1-methylethyl]thio]-2,6-bis(1,1-dimethylethyl)phenoxy]acetic Acid], a Novel Antioxidant and Anti-Inflammatory Compound: Cellular and Biochemical Characterization of Antioxidant Activity and Inhibition of Redox-Sensitive Inflammatory Gene Expression
    Charles Kunsch, Jayraz Luchoomun, Xi-lin Chen, Geraldine L. Dodd, Kanika S. Karu, Charles Q. Meng, Elaine M. Marino, Lyn K. Olliff, J. Daniel Piper, Fei-Hua Qiu, James A. Sikorski, Patricia K. Somers, Ki-Ling Suen, Suzanne Thomas, Anne M. Whalen, Martin A. Wasserman and Cynthia L. Sundell
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 492-501; DOI: https://doi.org/10.1124/jpet.104.080804
  • You have access
    Inhibitors of Poly(ADP-Ribose) Polymerase Modulate Signal Transduction Pathways and the Development of Bleomycin-Induced Lung Injury
    Tiziana Genovese, Emanuela Mazzon, Rosanna Di Paola, Carmelo Muià, Michael D. Threadgill, Achille P. Caputi, Christoph Thiemermann and Salvatore Cuzzocrea
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 529-538; DOI: https://doi.org/10.1124/jpet.104.080705
  • You have access
    Formation, Distribution, and Elimination of Infliximab and Anti-Infliximab Immune Complexes in Cynomolgus Monkeys
    Jeannie R. Rojas, Ronald P. Taylor, Mark R. Cunningham, Thomas J. Rutkoski, Joseph Vennarini, Haishan Jang, Martin A. Graham, Karel Geboes, Serge D. Rousselle and Carrie L. Wagner
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 578-585; DOI: https://doi.org/10.1124/jpet.104.079277
  • You have access
    Cloning and Characterization of Cyclooxygenase-1b (Putative Cyclooxygenase-3) in Rat
    James A. Snipes, Bela Kis, Gregory S. Shelness, James A. Hewett and David W. Busija
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 668-676; DOI: https://doi.org/10.1124/jpet.104.079533
  • You have access
    Inhibition of S-Adenosyl-l-homocysteine Hydrolase Induces Immunosuppression
    Qing-Li Wu, Yun-Feng Fu, Wen-Liang Zhou, Jun-Xia Wang, Yong-Hong Feng, Jing Liu, Jian-Yi Xu, Pei-Lan He, Ru Zhou, Wei Tang, Gui-Feng Wang, Yu Zhou, Yi-Fu Yang, Jian Ding, Xiao-Yu Li, Xiao-Ru Chen, Chong Yuan, Brian R. Lawson and Jian-Ping Zuo
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 705-711; DOI: https://doi.org/10.1124/jpet.104.080416

NEUROPHARMACOLOGY

  • You have access
    Time-Dependent Changes in Receptor/G-Protein Coupling in Rat Brain following Chronic Monoamine Transporter Blockade
    Kerry A. O'Connor, Linda J. Porrino, Huw M. L. Davies and Steven R. Childers
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 510-517; DOI: https://doi.org/10.1124/jpet.104.078451
  • You have access
    Molecular Determinants of Glycine-Independent Desensitization of NR1/NR2A Receptors
    Bo Hu and Fang Zheng
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 563-569; DOI: https://doi.org/10.1124/jpet.104.080168
  • You have access
    Clozapine Potentiation of N-Methyl-d-aspartate Receptor Currents in the Nucleus Accumbens: Role of NR2B and Protein Kinase A/Src Kinases
    Marion Wittmann, Michael J. Marino, Darrell A. Henze, Guy R. Seabrook and P. Jeffrey Conn
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 594-603; DOI: https://doi.org/10.1124/jpet.104.080200
  • You have access
    M2, M3, and M4 Receptor Subtypes Contribute to Muscarinic Potentiation of GABAergic Inputs to Spinal Dorsal Horn Neurons
    Hong-Mei Zhang, De-Pei Li, Shao-Rui Chen and Hui-Lin Pan
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 697-704; DOI: https://doi.org/10.1124/jpet.104.079939
  • You have access
    Improved Brain Uptake and Pharmacological Activity Profile of Morphine-6-Glucuronide Using a Peptide Vector-Mediated Strategy
    Jamal Temsamani, Cécile Bonnafous, Christophe Rousselle, Yannik Fraisse, Philippe Clair, Luc-André Granier, Anthony R. Rees, Michel Kaczorek and Jean-Michel Scherrmann
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 712-719; DOI: https://doi.org/10.1124/jpet.104.081000
  • You have access
    Nicotinic Receptor Subtypes in Rat Hippocampal Slices Are Differentially Sensitive to Desensitization and Early in Vivo Functional Up-Regulation by Nicotine and to Block by Bupropion
    Manickavasagom Alkondon and Edson X. Albuquerque
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 740-750; DOI: https://doi.org/10.1124/jpet.104.081232
  • You have access
    The Nonthiazolidinedione Tyrosine-Based Peroxisome Proliferator-Activated Receptor γ Ligand GW7845 Induces Apoptosis and Limits Migration and Invasion of Rat and Human Glioma Cells
    Christian Grommes, Gary E. Landreth, Uwe Schlegel and Michael T. Heneka
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 806-813; DOI: https://doi.org/10.1124/jpet.104.078972
  • You have access
    Anxiolytic- and Antidepressant-Like Profile of ATC0065 and ATC0175: Nonpeptidic and Orally Active Melanin-Concentrating Hormone Receptor 1 Antagonists
    Shigeyuki Chaki, Takeo Funakoshi, Shiho Hirota-Okuno, Mariko Nishiguchi, Toshiharu Shimazaki, Michihiko Iijima, Andrew J. Grottick, Kosuke Kanuma, Katsunori Omodera, Yoshinori Sekiguchi, Shigeru Okuyama, Thuy-Anh Tran, Graeme Semple and William Thomsen
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 831-839; DOI: https://doi.org/10.1124/jpet.104.081711
  • You have access
    WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-Octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a Novel 5-Hydroxytryptamine 2C Receptor-Selective Agonist with Anorectic Activity
    John Dunlop, Annmarie L. Sabb, Hossein Mazandarani, Jean Zhang, Sachin Kalgaonker, Eugenia Shukhina, Stacey Sukoff, Robert L. Vogel, Gary Stack, Lee Schechter, Boyd L. Harrison and Sharon Rosenzweig-Lipson
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 862-869; DOI: https://doi.org/10.1124/jpet.104.075382
  • You have access
    Cyclooxygenase-2 Is an Obligatory Factor in Methamphetamine-Induced Neurotoxicity
    David M. Thomas and Donald M. Kuhn
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 870-876; DOI: https://doi.org/10.1124/jpet.104.080242
  • You have access
    Quantitative Measurement of Changes in Amyloid-β(40) in the Rat Brain and Cerebrospinal Fluid following Treatment with the γ-Secretase Inhibitor LY-411575 [N2-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N1-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-l-alaninamide]
    Jonathan D. Best, Mark T. Jay, Franklin Otu, Jerome Ma, Alan Nadin, Semantha Ellis, Huw D. Lewis, Christine Pattison, Michael Reilly, Timothy Harrison, Mark S. Shearman, Toni L. Williamson and John R. Atack
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 902-908; DOI: https://doi.org/10.1124/jpet.104.081174

TOXICOLOGY

  • You have access
    The Role of Mitochondrial Uncoupling in 3,4-Methylenedioxymethamphetamine-Mediated Skeletal Muscle Hyperthermia and Rhabdomyolysis
    Daniel E. Rusyniak, Stephany L. Tandy, S. K. Hekmatyar, Edward Mills, David J. Smith, Navin Bansal, Darcy MacLellan, Mary-Ellen Harper and Jon E. Sprague
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 629-639; DOI: https://doi.org/10.1124/jpet.104.079236
  • You have access
    Specific Antibody Modulates Absorptive Transport and Metabolic Activation of Benzo[a]pyrene across Caco-2 Monolayers
    Stefan S. De Buck, Patrick Augustijns and Claude P. Muller
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 640-646; DOI: https://doi.org/10.1124/jpet.104.081034
  • You have access
    Methylmercury Induces a Spontaneous, Transient Slow Inward Chloride Current in Purkinje Cells of Rat Cerebellar Slices
    Yukun Yuan and William D. Atchison
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 751-764; DOI: https://doi.org/10.1124/jpet.104.080721
  • You have access
    Glycogen Synthase Kinase-3 Mediates Acetaminophen-Induced Apoptosis in Human Hepatoma Cells
    Patricia Macanas-Pirard, Nik-Soriani Yaacob, Pauline C. Lee, Julie C. Holder, Richard H. Hinton and George E. N. Kass
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 780-789; DOI: https://doi.org/10.1124/jpet.104.081364
  • You have access
    Mutagenic Effects of 4-Hydroxynonenal Triacetate, a Chemically Protected Form of the Lipid Peroxidation Product 4-Hydroxynonenal, as Assayed in L5178Y/Tk+/– Mouse Lymphoma Cells
    Sharda P. Singh, Tao Chen, Ling Chen, Nan Mei, Eric McLain, Victor Samokyszyn, John J. Thaden, Martha M. Moore and Piotr Zimniak
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 855-861; DOI: https://doi.org/10.1124/jpet.104.080754

LETTERS TO THE EDITOR

  • You have access
    Comments on “Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-d-aspartate Receptors in Rat Hippocampal Neurons”
    Pradeep Banerjee, Gary Samoriski and Sandeep Gupta
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 928-929; DOI: https://doi.org/10.1124/jpet.104.081976
  • You have access
    Response: Comments on “Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-d-aspartate Receptors in Rat Hippocampal Neurons”
    Yasco Aracava, Edna F. R. Pereira, Alfred Maelicke and Edson X. Albuquerque
    Journal of Pharmacology and Experimental Therapeutics May 2005, 313 (2) 930-933; DOI: https://doi.org/10.1124/jpet.104.082222
Back to top
PreviousNext

In this issue

Journal of Pharmacology and Experimental Therapeutics: 313 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 313, Issue 2
1 May 2005
  • Table of Contents
  • About the Cover
  • Index by author
Sign up for alerts

Jump to

  • PERSPECTIVES IN PHARMACOLOGY
  • ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION
  • BEHAVIORAL PHARMACOLOGY
  • CARDIOVASCULAR
  • CELLULAR AND MOLECULAR
  • ENDOCRINE AND REPRODUCTIVE
  • GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL
  • INFLAMMATION AND IMMUNOPHARMACOLOGY
  • NEUROPHARMACOLOGY
  • TOXICOLOGY
  • LETTERS TO THE EDITOR
  • Most Cited
  • Most Read
Loading
  • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.
  • Functional Selectivity and Classical Concepts of Quantitative Pharmacology
  • Abl Protein-Tyrosine Kinase Inhibitor STI571 Inhibits In Vitro Signal Transduction Mediated by c-Kit and Platelet-Derived Growth Factor Receptors
  • The Prediction of Human Pharmacokinetic Parameters from Preclinical and In Vitro Metabolism Data
  • A METHOD FOR DETERMINING LOSS OF PAIN SENSATION
More...
Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About JPET
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Drug Metabolism and Disposition
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-0103 (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics