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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

The Grapefruit Juice Effect Is Not Limited to Cytochrome P450 (P450) 3A4: Evidence for Bergamottin-Dependent Inactivation, Heme Destruction, and Covalent Binding to Protein in P450s 2B6 and 3A5

Hsia-lien Lin, Ute M. Kent and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics April 2005, 313 (1) 154-164; DOI: https://doi.org/10.1124/jpet.104.079608
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

The Grapefruit Juice Effect Is Not Limited to Cytochrome P450 (P450) 3A4: Evidence for Bergamottin-Dependent Inactivation, Heme Destruction, and Covalent Binding to Protein in P450s 2B6 and 3A5

Hsia-lien Lin, Ute M. Kent and Paul F. Hollenberg
Journal of Pharmacology and Experimental Therapeutics April 1, 2005, 313 (1) 154-164; DOI: https://doi.org/10.1124/jpet.104.079608
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