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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Investigation of Efflux Transport of Dehydroepiandrosterone Sulfate and Mitoxantrone at the Mouse Blood-Brain Barrier: A Minor Role of Breast Cancer Resistance Protein

Young-Joo Lee, Hiroyuki Kusuhara, Johan W. Jonker, Alfred H. Schinkel and Yuichi Sugiyama
Journal of Pharmacology and Experimental Therapeutics January 2005, 312 (1) 44-52; DOI: https://doi.org/10.1124/jpet.104.073320

Article Information

vol. 312 no. 1 44-52
DOI 
https://doi.org/10.1124/jpet.104.073320
PubMed 
15448171
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received June 27, 2004
  • Accepted September 22, 2004
  • Published online December 15, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Young-Joo Lee,
  2. Hiroyuki Kusuhara,
  3. Johan W. Jonker,
  4. Alfred H. Schinkel and
  5. Yuichi Sugiyama
  1. The Graduate School of Pharmaceutical Sciences, the University of Tokyo, Bunkyo-ku, Tokyo, Japan (Y.-J.L., H.K., Y.S.); and Division of Experimental Therapy, the Netherlands Cancer Institute, Amsterdam, the Netherlands (J.W.J., A.H.S.)
  1. Address correspondence to:
    Dr. Yuichi Sugiyama, Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan. E-mail: sugiyama{at}mol.f.u-tokyo.ac.jp
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Investigation of Efflux Transport of Dehydroepiandrosterone Sulfate and Mitoxantrone at the Mouse Blood-Brain Barrier: A Minor Role of Breast Cancer Resistance Protein

Young-Joo Lee, Hiroyuki Kusuhara, Johan W. Jonker, Alfred H. Schinkel and Yuichi Sugiyama
Journal of Pharmacology and Experimental Therapeutics January 1, 2005, 312 (1) 44-52; DOI: https://doi.org/10.1124/jpet.104.073320
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