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Research ArticleCARDIOVASCULAR

Pentamidine-Induced Long QT Syndrome and Block of hERG Trafficking

Yuri A. Kuryshev, Eckhard Ficker, Lu Wang, Peter Hawryluk, Adrienne T. Dennis, Barbara A. Wible, Arthur M. Brown, Jiesheng Kang, Xiao-Liang Chen, Kaoru Sawamura, William Reynolds and David Rampe
Journal of Pharmacology and Experimental Therapeutics January 2005, 312 (1) 316-323; DOI: https://doi.org/10.1124/jpet.104.073692

Article Information

vol. 312 no. 1 316-323
DOI 
https://doi.org/10.1124/jpet.104.073692
PubMed 
15340016
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 5, 2004
  • Accepted August 31, 2004
  • Published online December 15, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yuri A. Kuryshev,
  2. Eckhard Ficker,
  3. Lu Wang,
  4. Peter Hawryluk,
  5. Adrienne T. Dennis,
  6. Barbara A. Wible,
  7. Arthur M. Brown,
  8. Jiesheng Kang,
  9. Xiao-Liang Chen,
  10. Kaoru Sawamura,
  11. William Reynolds and
  12. David Rampe
  1. Rammelkamp Center for Education and Research, MetroHealth Campus, Case Western Reserve University, Cleveland, Ohio (Y.A.K., E.F., L.W., A.T.D., B.A.W., A.M.B.); ChanTest Inc., Cleveland, Ohio (P.H., B.A.W., A.M.B.); and Drug Safety Evaluation, Aventis Pharmaceuticals Inc., Bridgewater, New Jersey (J.K., X.-L.C., K.S., W.R., D.R.)
  1. Address correspondence to:
    Eckhard Ficker, Rammelkamp Center, MetroHealth Medical Center, 2500 MetroHealth Drive, Cleveland, OH 44109-1998. Email: eficker{at}metrohealth.org
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Research ArticleCARDIOVASCULAR

Pentamidine-Induced Long QT Syndrome and Block of hERG Trafficking

Yuri A. Kuryshev, Eckhard Ficker, Lu Wang, Peter Hawryluk, Adrienne T. Dennis, Barbara A. Wible, Arthur M. Brown, Jiesheng Kang, Xiao-Liang Chen, Kaoru Sawamura, William Reynolds and David Rampe
Journal of Pharmacology and Experimental Therapeutics January 1, 2005, 312 (1) 316-323; DOI: https://doi.org/10.1124/jpet.104.073692
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