Advertisement
Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Hepatobiliary Disposition of the Metabolically Stable Opioid Peptide [d-Pen2, d-Pen5]-Enkephalin (DPDPE): Pharmacokinetic Consequences of the Interplay between Multiple Transport Systems

Keith A. Hoffmaster, Maciej J. Zamek-Gliszczynski, Gary M. Pollack and Kim L. R. Brouwer
Journal of Pharmacology and Experimental Therapeutics December 2004, 311 (3) 1203-1210; DOI: https://doi.org/10.1124/jpet.104.070201

Article Information

vol. 311 no. 3 1203-1210
DOI 
https://doi.org/10.1124/jpet.104.070201
PubMed 
15302892
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received April 16, 2004
  • Accepted August 6, 2004
  • Published online November 18, 2004.

Article Versions

Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Keith A. Hoffmaster,
  2. Maciej J. Zamek-Gliszczynski,
  3. Gary M. Pollack and
  4. Kim L. R. Brouwer
  1. Division of Drug Delivery and Disposition, School of Pharmacy, University of North Carolina, Chapel Hill, North Carolina
  1. Address correspondence to:
    Dr. Kim L. R. Brouwer, CB#7360, Kerr Hall, Rm 2312, School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7360. E-mail: kbrouwer{at}unc.edu
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2004 to September 2024

AbstractFullPdf
Aug 200465090
Sep 200455054
Oct 200457033
Nov 2004883186
Dec 2004905740
Jan 2005734828
Feb 2005302720
Mar 2005303730
Apr 200591716
May 20057178
Jun 200562625
Jul 2005143510
Aug 2005172217
Sep 20056113
Oct 20054142
Nov 200581915
Dec 20056219
Jan 200663925
Feb 2006112216
Mar 20062158
Apr 20065197
May 20063109
Jun 20064138
Jul 20064116
Aug 2006267
Sep 2006454
Oct 20062127
Nov 20063910
Dec 2006888
Jan 20072106
Feb 20071711
Mar 200721712
Apr 20073149
May 2007244
Jun 20071107
Jul 2007545
Aug 2007485
Sep 200716915
Oct 200751312
Nov 20071117
Dec 2007279
Jan 20080105
Feb 200831112
Mar 2008398
Apr 2008688
May 20087812
Jun 200861710
Jul 20086810
Aug 2008486
Sep 20081159
Oct 200816114
Nov 20087184
Dec 2008844
Jan 20094710
Feb 2009542
Mar 20098108
Apr 2009258
May 2009138
Jun 2009587
Jul 2009468
Aug 2009536
Sep 2009675
Oct 2009743
Nov 2009411
Dec 2009521
Jan 2010121214
Feb 20101034
Mar 20108412
Apr 2010745
May 2010756
Jun 2010345
Jul 20109610
Aug 201041014
Sep 2010222
Oct 2010526
Nov 20106311
Dec 2010573
Jan 20111818
Feb 20118318
Mar 201113711
Apr 201111515
May 20115612
Jun 20111068
Jul 201113615
Aug 201112210
Sep 201110211
Oct 2011759
Nov 2011837
Dec 201113412
Jan 201210712
Feb 201271114
Mar 20127911
Apr 201217514
May 20127715
Jun 2012658
Jul 201231417
Aug 201291012
Sep 2012559
Oct 20127310
Nov 20121179
Dec 2012488
Jan 2013589
Feb 20131345
Mar 201361011
Apr 20134910
May 2013789
Jun 2013013
Jul 2013563
Aug 2013366
Sep 20131245
Oct 20131131
Nov 2013420
Dec 2013343
Jan 2014835
Feb 20141325
Mar 20144202
Apr 2014932
May 20147910
Jun 2014923
Jul 20141393
Aug 2014081
Sep 2014224
Oct 2014112
Nov 2014520
Dec 2014223
Jan 2015444
Feb 2015212
Mar 2015321
Apr 20153171
May 2015442
Jun 2015733
Jul 2015346
Aug 2015010
Sep 2015643
Oct 2015202
Nov 2015800
Dec 20151445
Jan 20161044
Feb 2016856
Mar 20163128
Apr 2016243
May 2016361
Jun 2016558
Jul 2016206
Aug 20163112
Sep 2016457
Oct 20166149
Nov 20160228
Dec 2016080
Jan 2017080
Feb 2017060
Mar 20171181
Apr 2017030
May 2017150
Jun 2017040
Jul 2017063
Aug 2017061
Sep 2017087
Oct 2017022
Nov 2017193
Dec 2017093
Jan 20180130
Feb 20180238
Mar 2018184
Apr 2018083
May 2018072
Jun 2018035
Jul 2018081
Aug 20181108
Sep 2018042
Oct 20181104
Nov 2018186
Dec 2018514
Jan 2019500
Feb 2019411
Mar 2019900
Apr 2019600
May 2019200
Jun 2019400
Jul 2019514
Aug 2019900
Sep 2019801
Oct 2019811
Nov 20191010
Dec 20192041
Jan 2020900
Feb 20201000
Mar 2020733
Apr 2020700
May 2020300
Jun 20201100
Jul 2020400
Aug 2020200
Sep 2020230
Oct 2020500
Nov 2020711
Dec 20201653
Jan 20215132
Feb 20217143
Mar 20211132
Apr 2021910
May 20212462
Jun 20211780
Jul 20212013
Aug 20213172
Sep 2021941
Oct 2021920
Nov 20211320
Dec 20211731
Jan 2022926
Feb 20221011
Mar 2022921
Apr 20221704
May 20221010
Jun 2022810
Jul 20221221
Aug 20221010
Sep 20221171
Oct 20221350
Nov 2022632
Dec 20221100
Jan 2023422
Feb 2023720
Mar 2023920
Apr 2023623
May 20231535
Jun 2023110
Jul 20231032
Aug 2023532
Sep 2023730
Oct 2023925
Nov 2023203
Dec 20231870
Jan 2024414
Feb 202447101
Mar 20241311
Apr 20242531
May 2024630
Jun 2024725
Jul 20242150
Aug 20242525
Sep 20242200

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Hepatobiliary Disposition of the Metabolically Stable Opioid Peptide [d-Pen2, d-Pen5]-Enkephalin (DPDPE): Pharmacokinetic Consequences of the Interplay between Multiple Transport Systems

Keith A. Hoffmaster, Maciej J. Zamek-Gliszczynski, Gary M. Pollack and Kim L. R. Brouwer
Journal of Pharmacology and Experimental Therapeutics December 1, 2004, 311 (3) 1203-1210; DOI: https://doi.org/10.1124/jpet.104.070201
Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement