Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

School of Pharmaceutical Sciences, Showa University, Tokyo, Japan (Y.Sh., H.S.); and Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (M.H., Y.Su.)

Address correspondence to:
Dr. Yuichi Sugiyama, Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1, Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. E-mail: sugiyama{at}mol.f.u-tokyo.ac.jp

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Feb 2018	48	42	26
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Apr 2018	43	36	18
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Jan 2023	37	23	9
Feb 2023	20	12	5
Mar 2023	45	16	4