Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the Hepatic Uptake of Pitavastatin in Humans

Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan (M.H., K.M., Y.Su.); and School of Pharmaceutical Sciences, Showa University, Tokyo, Japan (Y.Sh.)

Address correspondence to:
Dr. Yuichi Sugiyama, Department of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan. E-mail: sugiyama{at}mol.f.u-tokyo.ac.jp

View Full Text

Statistics from Altmetric.com

Article usage

Article usage: May 2004 to May 2022

	Abstract	Full	Pdf
May 2004	22	0	62
Jun 2004	80	0	187
Jul 2004	84	0	126
Aug 2004	81	0	79
Sep 2004	104	54	182
Oct 2004	117	140	117
Nov 2004	72	121	96
Dec 2004	63	71	50
Jan 2005	43	66	29
Feb 2005	25	82	47
Mar 2005	33	70	35
Apr 2005	19	72	46
May 2005	17	87	59
Jun 2005	22	97	56
Jul 2005	18	55	36
Aug 2005	20	57	36
Sep 2005	20	41	45
Oct 2005	15	57	55
Nov 2005	16	66	52
Dec 2005	9	49	47
Jan 2006	8	55	42
Feb 2006	19	60	36
Mar 2006	7	56	51
Apr 2006	4	52	54
May 2006	6	64	49
Jun 2006	10	55	46
Jul 2006	10	47	34
Aug 2006	6	41	36
Sep 2006	9	48	46
Oct 2006	10	48	37
Nov 2006	7	43	37
Dec 2006	7	32	27
Jan 2007	10	35	31
Feb 2007	3	36	32
Mar 2007	6	31	29
Apr 2007	8	44	54
May 2007	11	48	46
Jun 2007	8	46	38
Jul 2007	10	41	40
Aug 2007	12	37	34
Sep 2007	12	43	51
Oct 2007	23	61	55
Nov 2007	10	60	52
Dec 2007	7	28	31
Jan 2008	22	49	55
Feb 2008	13	61	53
Mar 2008	10	41	52
Apr 2008	40	50	72
May 2008	30	36	51
Jun 2008	28	51	59
Jul 2008	23	47	51
Aug 2008	22	39	36
Sep 2008	11	36	48
Oct 2008	26	42	45
Nov 2008	37	46	48
Dec 2008	21	31	27
Jan 2009	25	25	36
Feb 2009	37	30	30
Mar 2009	26	43	43
Apr 2009	19	43	43
May 2009	21	35	39
Jun 2009	24	48	53
Jul 2009	20	37	38
Aug 2009	23	33	38
Sep 2009	31	51	36
Oct 2009	50	38	57
Nov 2009	31	28	45
Dec 2009	23	16	24
Jan 2010	52	37	27
Feb 2010	46	33	35
Mar 2010	46	38	48
Apr 2010	58	34	31
May 2010	33	33	32
Jun 2010	45	39	29
Jul 2010	56	29	37
Aug 2010	72	33	35
Sep 2010	57	36	38
Oct 2010	49	45	43
Nov 2010	67	42	46
Dec 2010	30	36	29
Jan 2011	61	43	48
Feb 2011	57	60	53
Mar 2011	72	60	56
Apr 2011	52	49	53
May 2011	54	37	41
Jun 2011	58	42	66
Jul 2011	57	47	58
Aug 2011	62	58	59
Sep 2011	68	53	51
Oct 2011	71	54	49
Nov 2011	78	46	37
Dec 2011	81	44	50
Jan 2012	62	35	39
Feb 2012	55	54	61
Mar 2012	84	40	57
Apr 2012	50	48	64
May 2012	84	37	64
Jun 2012	67	38	47
Jul 2012	55	44	53
Aug 2012	44	29	46
Sep 2012	31	43	56
Oct 2012	48	42	70
Nov 2012	43	40	53
Dec 2012	43	43	42
Jan 2013	34	43	37
Feb 2013	53	41	40
Mar 2013	44	46	40
Apr 2013	50	41	41
May 2013	55	42	43
Jun 2013	24	40	36
Jul 2013	24	21	15
Aug 2013	30	42	36
Sep 2013	34	42	34
Oct 2013	36	53	48
Nov 2013	44	30	34
Dec 2013	36	33	38
Jan 2014	38	51	43
Feb 2014	33	26	25
Mar 2014	63	50	65
Apr 2014	43	56	78
May 2014	48	69	54
Jun 2014	39	47	34
Jul 2014	56	71	49
Aug 2014	35	42	50
Sep 2014	81	41	48
Oct 2014	29	41	31
Nov 2014	34	38	35
Dec 2014	24	28	29
Jan 2015	23	28	26
Feb 2015	29	38	30
Mar 2015	10	44	26
Apr 2015	29	62	48
May 2015	17	43	148
Jun 2015	38	50	55
Jul 2015	19	23	26
Aug 2015	32	30	29
Sep 2015	34	29	33
Oct 2015	31	25	27
Nov 2015	17	28	22
Dec 2015	14	28	23
Jan 2016	30	40	42
Feb 2016	21	25	23
Mar 2016	47	34	43
Apr 2016	27	30	44
May 2016	21	33	38
Jun 2016	23	28	45
Jul 2016	24	42	38
Aug 2016	40	37	34
Sep 2016	38	83	57
Oct 2016	18	49	24
Nov 2016	12	69	25
Dec 2016	4	49	12
Jan 2017	10	63	24
Feb 2017	24	68	45
Mar 2017	11	76	34
Apr 2017	9	63	51
May 2017	5	71	41
Jun 2017	6	87	34
Jul 2017	25	67	53
Aug 2017	9	87	35
Sep 2017	10	71	22
Oct 2017	8	94	31
Nov 2017	5	168	29
Dec 2017	4	181	24
Jan 2018	11	100	23
Feb 2018	4	69	37
Mar 2018	10	62	22
Apr 2018	7	61	25
May 2018	10	81	34
Jun 2018	3	38	22
Jul 2018	4	54	22
Aug 2018	5	43	15
Sep 2018	7	52	36
Oct 2018	11	46	43
Nov 2018	6	42	30
Dec 2018	55	19	19
Jan 2019	34	16	6
Feb 2019	42	15	12
Mar 2019	45	21	11
Apr 2019	44	13	4
May 2019	39	17	12
Jun 2019	34	1	9
Jul 2019	60	16	8
Aug 2019	39	20	24
Sep 2019	34	14	7
Oct 2019	15	16	12
Nov 2019	47	18	7
Dec 2019	39	22	7
Jan 2020	32	15	10
Feb 2020	40	10	5
Mar 2020	32	28	20
Apr 2020	35	8	7
May 2020	58	9	8
Jun 2020	47	17	18
Jul 2020	17	7	11
Aug 2020	15	11	11
Sep 2020	38	19	8
Oct 2020	40	18	10
Nov 2020	21	4	4
Dec 2020	75	24	12
Jan 2021	49	82	15
Feb 2021	29	72	7
Mar 2021	42	23	6
Apr 2021	30	23	6
May 2021	57	33	9
Jun 2021	36	57	8
Jul 2021	39	23	11
Aug 2021	23	45	6
Sep 2021	23	25	9
Oct 2021	51	9	2
Nov 2021	25	9	7
Dec 2021	46	13	10
Jan 2022	35	24	11
Feb 2022	30	9	4
Mar 2022	53	10	6
Apr 2022	34	6	10
May 2022	4	6	3