Advertisement

Index by author

September 01, 2004; Volume 310,Issue 3

A

  1. Andersson, Carl Magnus

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  2. Arias, Esperanza

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  3. Arnone, Michèle

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  4. Aubin, N.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

B

  1. Baer, Philip G.

    1. Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-l-tyrosine Peroxisome Proliferator-Activated Receptor-γ Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
      Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown and Terence Bennett
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.104.068817

  2. Balázsa, Tamás

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

  3. Banfi, Cristina

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  4. Barcella, Simona

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  5. Barneoud, P.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  6. Barth, Francis

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  7. Bennett, Terence

    1. Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-l-tyrosine Peroxisome Proliferator-Activated Receptor-γ Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
      Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown and Terence Bennett
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.104.068817

  8. Benowitz, Neal L.

    1. Mentholated Cigarette Smoking Inhibits Nicotine Metabolism
      Neal L. Benowitz, Brenda Herrera and Peyton Jacob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1208-1215; DOI: https://doi.org/10.1124/jpet.104.066902

  9. Bettler, Bernhard

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  10. Blair, Robert E.

    1. Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
      Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay and Robert J. DeLorenzo
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 871-880; DOI: https://doi.org/10.1124/jpet.104.068478

  11. Bradbury, J. Alyce

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  12. Bradley, Stefania Risso

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  13. Brann, Mark R.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  14. Brausch, Isolde

    1. Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
      Huige Li, Ning Xia, Isolde Brausch, Ying Yao and Ulrich Förstermann
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 926-932; DOI: https://doi.org/10.1124/jpet.104.066639

  15. Brimijoin, Stephen

    1. An Engineered Cocaine Hydrolase Blunts and Reverses Cardiovascular Responses to Cocaine in Rats
      Yang Gao and Stephen Brimijoin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1046-1052; DOI: https://doi.org/10.1124/jpet.104.068122

  16. Brown, Kathleen K.

    1. Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-l-tyrosine Peroxisome Proliferator-Activated Receptor-γ Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
      Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown and Terence Bennett
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.104.068817

  17. Bubar, Marcy J.

    1. Contribution of Serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2 Receptor Subtypes to the Hyperlocomotor Effects of Cocaine: Acute and Chronic Pharmacological Analyses
      Malgorzata Filip, Marcy J. Bubar and Kathryn A. Cunningham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1246-1254; DOI: https://doi.org/10.1124/jpet.104.068841

  18. Bui, Tot

    1. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
      Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen and Rodney J. Y. Ho
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1199-1207; DOI: https://doi.org/10.1124/jpet.104.065383

  19. Buikema, Hendrik

    1. Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
      Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis and Hendrik Buikema
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1183-1189; DOI: https://doi.org/10.1124/jpet.104.067272

  20. Bumpus, Namandjé N.

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  21. Burcham, Philip C.

    1. Strong Protein Adduct Trapping Accompanies Abolition of Acrolein-Mediated Hepatotoxicity by Hydralazine in Mice
      Lisa M. Kaminskas, Simon M. Pyke and Philip C. Burcham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1003-1010; DOI: https://doi.org/10.1124/jpet.104.067330

  22. Burnier, P.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

C

  1. Cagetti, Elisabetta

    1. Altered Pharmacology of Synaptic and Extrasynaptic GABAA Receptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence
      Jing Liang, Elisabetta Cagetti, Richard W. Olsen and Igor Spigelman
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1234-1245; DOI: https://doi.org/10.1124/jpet.104.067983

  2. Caille, D.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  3. Campiani, Giuseppe

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  4. Carter, C.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  5. Challiss, R. A. John

    1. Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
      Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski and R. A. John Challiss
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1255-1265; DOI: https://doi.org/10.1124/jpet.104.067140

  6. Chaperon, Frederique

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  7. Charieras, T.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  8. Chaudary, Naz

    1. The Adenosine Transporter, mENT1, Is a Target for Adenosine Receptor Signaling and Protein Kinase Cϵ in Hypoxic and Pharmacological Preconditioning in the Mouse Cardiomyocyte Cell Line, HL-1
      Naz Chaudary, Zlatina Naydenova, Irina Shuralyova and Imogen R. Coe
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1190-1198; DOI: https://doi.org/10.1124/jpet.104.067157

  9. Chen, Feng

    1. Chronic Antidepressant Treatment Causes a Selective Reduction of μ-Opioid Receptor Binding and Functional Coupling to G Proteins in the Amygdala of Fawn-Hooded Rats
      Feng Chen and Andrew J. Lawrence
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1020-1026; DOI: https://doi.org/10.1124/jpet.104.068692

  10. Chen, Jun

    1. Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates
      Xiaobin Jia, Jun Chen, Huimin Lin and Ming Hu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1103-1113; DOI: https://doi.org/10.1124/jpet.104.068403

  11. Cirino, Giuseppe

    1. Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-κB
      John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato and Stefano Fiorucci
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1096-1102; DOI: https://doi.org/10.1124/jpet.104.067850

  12. Coe, Imogen R.

    1. The Adenosine Transporter, mENT1, Is a Target for Adenosine Receptor Signaling and Protein Kinase Cϵ in Hypoxic and Pharmacological Preconditioning in the Mouse Cardiomyocyte Cell Line, HL-1
      Naz Chaudary, Zlatina Naydenova, Irina Shuralyova and Imogen R. Coe
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1190-1198; DOI: https://doi.org/10.1124/jpet.104.067157

  13. Coffey, G. P.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  14. Congy, Christian

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  15. Coulter, Sherry J.

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  16. Coy, David H.

    1. Development of Bombesin Analogs with Conformationally Restricted Amino Acid Substitutions with Enhanced Selectivity for the Orphan Receptor Human Bombesin Receptor Subtype 3
      Samuel A. Mantey, David H. Coy, Laurence K. Entsuah and Robert T. Jensen
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1161-1170; DOI: https://doi.org/10.1124/jpet.104.066761

  17. Croke, David T.

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  18. Crooks, Peter A.

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

  19. Cryan, John F.

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  20. Cunningham, Kathryn A.

    1. Contribution of Serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2 Receptor Subtypes to the Hyperlocomotor Effects of Cocaine: Acute and Chronic Pharmacological Analyses
      Malgorzata Filip, Marcy J. Bubar and Kathryn A. Cunningham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1246-1254; DOI: https://doi.org/10.1124/jpet.104.068841

  21. Curet, O.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

D

  1. D'Amico, Michele

    1. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

  2. D'Orio, Vincent

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  3. Davis, Robert E.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  4. DeLorenzo, Robert J.

    1. Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
      Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay and Robert J. DeLorenzo
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 871-880; DOI: https://doi.org/10.1124/jpet.104.068478

  5. de los Rios, Cristobal

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  6. DeLozier, Tracy C.

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  7. Del Soldato, Piero

    1. Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-κB
      John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato and Stefano Fiorucci
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1096-1102; DOI: https://doi.org/10.1124/jpet.104.067850
    2. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

  8. De Simoni, Grazia

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  9. Desta, Zeruesenay

    1. Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6
      Zeruesenay Desta, Bryan A. Ward, Nadia V. Soukhova and David A. Flockhart
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1062-1075; DOI: https://doi.org/10.1124/jpet.104.065607

  10. de Zeeuw, Dick

    1. Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
      Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis and Hendrik Buikema
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1183-1189; DOI: https://doi.org/10.1124/jpet.104.067272

  11. Di Filippo, Clara

    1. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

  12. Dogné, Jean-Michel

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  13. Dolber, Paul C.

    1. Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
      Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor and Paul C. Dolber
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1266-1272; DOI: https://doi.org/10.1124/jpet.103.063842

  14. Dunlop, John

    1. Ligand Dependency of 5-Hydroxytryptamine 2C Receptor Internalization
      Brian D. Schlag, Zhuangwei Lou, Myles Fennell and John Dunlop
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 865-870; DOI: https://doi.org/10.1124/jpet.104.067306

  15. Dwoskin, Linda P.

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

E

  1. Eckert, R.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  2. Entsuah, Laurence K.

    1. Development of Bombesin Analogs with Conformationally Restricted Amino Acid Substitutions with Enhanced Selectivity for the Orphan Receptor Human Bombesin Receptor Subtype 3
      Samuel A. Mantey, David H. Coy, Laurence K. Entsuah and Robert T. Jensen
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1161-1170; DOI: https://doi.org/10.1124/jpet.104.066761

  3. Erdélyi, Ferenc

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

  4. Erickson, Kelly

    1. Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in Nerve Growth Factor-Treated PC12 Cells
      Hiroshi Ishida, Xieping Zhang, Kelly Erickson and Prabhati Ray
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 881-889; DOI: https://doi.org/10.1124/jpet.104.065318

  5. Eshleman, Amy J.

    1. Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
      Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1142-1151; DOI: https://doi.org/10.1124/jpet.104.067314

F

  1. Fabis, Marzena J.

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  2. Fennell, Myles

    1. Ligand Dependency of 5-Hydroxytryptamine 2C Receptor Internalization
      Brian D. Schlag, Zhuangwei Lou, Myles Fennell and John Dunlop
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 865-870; DOI: https://doi.org/10.1124/jpet.104.067306

  3. Fielder, P. J.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  4. Fienberg, Allen A.

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  5. Filip, Malgorzata

    1. Contribution of Serotonin (5-Hydroxytryptamine; 5-HT) 5-HT2 Receptor Subtypes to the Hyperlocomotor Effects of Cocaine: Acute and Chronic Pharmacological Analyses
      Malgorzata Filip, Marcy J. Bubar and Kathryn A. Cunningham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1246-1254; DOI: https://doi.org/10.1124/jpet.104.068841

  6. Finance, Olivier

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  7. Fiorucci, Stefano

    1. Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-κB
      John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato and Stefano Fiorucci
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1096-1102; DOI: https://doi.org/10.1124/jpet.104.067850

  8. Flockhart, David A.

    1. Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6
      Zeruesenay Desta, Bryan A. Ward, Nadia V. Soukhova and David A. Flockhart
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1062-1075; DOI: https://doi.org/10.1124/jpet.104.065607

  9. Foley, Julie

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  10. Forkert, Poh-Gek

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  11. Förstermann, Ulrich

    1. Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
      Huige Li, Ning Xia, Isolde Brausch, Ying Yao and Ulrich Förstermann
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 926-932; DOI: https://doi.org/10.1124/jpet.104.066639

  12. Froestl, Wolfgang

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  13. Fujiwara, Hironori

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

G

  1. Gao, Yang

    1. An Engineered Cocaine Hydrolase Blunts and Reverses Cardiovascular Responses to Cocaine in Rats
      Yang Gao and Stephen Brimijoin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1046-1052; DOI: https://doi.org/10.1124/jpet.104.068122

  2. García, Antonio G.

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  3. Gardes, A.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  4. Gardiner, Sheila M

    1. Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-l-tyrosine Peroxisome Proliferator-Activated Receptor-γ Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
      Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown and Terence Bennett
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.104.068817

  5. Gelosa, Paolo

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  6. Gentsch, Conrad

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  7. George, P.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  8. Ghanayem, Burhan I.

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  9. Ghuysen, Alexandre

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  10. Gianazza, Elisabetta

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  11. Goldstein, Joyce A.

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  12. Grabovsky, Yury

    1. Isobolographic Analysis for Combinations of a Full and Partial Agonist: Curved Isoboles
      Yury Grabovsky and Ronald J. Tallarida
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 981-986; DOI: https://doi.org/10.1124/jpet.104.067264

  13. Greene, Lisa M.

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  14. Greengard, Paul

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  15. Grinevich, Vladimir P.

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

  16. Gschwend, Simone

    1. Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
      Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis and Hendrik Buikema
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1183-1189; DOI: https://doi.org/10.1124/jpet.104.067272

  17. Gu, Baojun

    1. Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
      Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor and Paul C. Dolber
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1266-1272; DOI: https://doi.org/10.1124/jpet.103.063842

  18. Gubisne-Haberle, Diana

    1. Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
      Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson and Peter H. Yu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1125-1132; DOI: https://doi.org/10.1124/jpet.104.068601

  19. Guerrini, Uliano

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  20. Gupta, Paul

    1. Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
      Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski and R. A. John Challiss
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1255-1265; DOI: https://doi.org/10.1124/jpet.104.067140

H

  1. Hacksell, Uli

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  2. Hanson, Julien

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  3. Harleton, Erin

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  4. Harvey, Scott C.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  5. Hattori, Kouji

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  6. Herrera, Brenda

    1. Mentholated Cigarette Smoking Inhibits Nicotine Metabolism
      Neal L. Benowitz, Brenda Herrera and Peyton Jacob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1208-1215; DOI: https://doi.org/10.1124/jpet.104.066902

  7. Hill, Wayne

    1. Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
      Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson and Peter H. Yu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1125-1132; DOI: https://doi.org/10.1124/jpet.104.068601

  8. Hiraizumi-Hiraoka, Yasuko

    1. Identification of α-1L Adrenoceptor in Rabbit Ear Artery
      Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki and Ikunobu Muramatsu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 995-1002; DOI: https://doi.org/10.1124/jpet.104.066985

  9. Ho, Rodney J. Y.

    1. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
      Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen and Rodney J. Y. Ho
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1199-1207; DOI: https://doi.org/10.1124/jpet.104.065383

  10. Hollenberg, Paul F.

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  11. Hooper, D. Craig

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  12. Hu, Ming

    1. Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates
      Xiaobin Jia, Jun Chen, Huimin Lin and Ming Hu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1103-1113; DOI: https://doi.org/10.1124/jpet.104.068403

I

  1. Ignatowski, Tracey A.

    1. Brain-Derived Tumor Necrosis Factor-α and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant
      Jessica L. Reynolds, Tracey A. Ignatowski, Reeteka Sud and Robert N. Spengler
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1216-1225; DOI: https://doi.org/10.1124/jpet.104.067835

  2. Ikeda, Mizuho

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  3. Inoue, Koki

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  4. Ishida, Hiroshi

    1. Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in Nerve Growth Factor-Treated PC12 Cells
      Hiroshi Ishida, Xieping Zhang, Kelly Erickson and Prabhati Ray
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 881-889; DOI: https://doi.org/10.1124/jpet.104.065318

  5. Ishida, Junya

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  6. Ishizuka, Masaaki

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

  7. Isobe, Toshiaki

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

  8. Iwashita, Akinori

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

J

  1. Jacob, Peyton

    1. Mentholated Cigarette Smoking Inhibits Nicotine Metabolism
      Neal L. Benowitz, Brenda Herrera and Peyton Jacob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1208-1215; DOI: https://doi.org/10.1124/jpet.104.066902

  2. Janowsky, Aaron

    1. Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
      Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1142-1151; DOI: https://doi.org/10.1124/jpet.104.067314

  3. Jegham, S.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  4. Jensen, Robert T.

    1. Development of Bombesin Analogs with Conformationally Restricted Amino Acid Substitutions with Enhanced Selectivity for the Orphan Receptor Human Bombesin Receptor Subtype 3
      Samuel A. Mantey, David H. Coy, Laurence K. Entsuah and Robert T. Jensen
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1161-1170; DOI: https://doi.org/10.1124/jpet.104.066761

  5. Jia, Xiaobin

    1. Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates
      Xiaobin Jia, Jun Chen, Huimin Lin and Ming Hu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1103-1113; DOI: https://doi.org/10.1124/jpet.104.068403

  6. Johnson, Robert A.

    1. Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
      Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1142-1151; DOI: https://doi.org/10.1124/jpet.104.067314

K

  1. Kakei, Masafumi

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  2. Kaminskas, Lisa M.

    1. Strong Protein Adduct Trapping Accompanies Abolition of Acrolein-Mediated Hepatotoxicity by Hydralazine in Mice
      Lisa M. Kaminskas, Simon M. Pyke and Philip C. Burcham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1003-1010; DOI: https://doi.org/10.1124/jpet.104.067330

  3. Kaupmann, Klemens

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  4. Kazachkov, Mychaylo

    1. Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
      Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson and Peter H. Yu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1125-1132; DOI: https://doi.org/10.1124/jpet.104.068601

  5. Kean, Rhonda B.

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  6. Kelly, Peter H.

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  7. Kent, Ute M.

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  8. Kinsella, Anthony

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  9. Kocks, Menno J. A.

    1. Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
      Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis and Hendrik Buikema
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1183-1189; DOI: https://doi.org/10.1124/jpet.104.067272

  10. Köfalvi, Attila

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

  11. Kold, Henriette

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  12. Kolh, Philippe

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  13. Koob, George F.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  14. Krishna, Murali C.

    1. Novel Pharmacokinetic Measurement Using Electron Paramagnetic Resonance Spectroscopy and Simulation of in Vivo Decay of Various Nitroxyl Spin Probes in Mouse Blood
      Ken-ichiro Matsumoto, Murali C. Krishna and James B. Mitchell
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1076-1083; DOI: https://doi.org/10.1124/jpet.104.066647

L

  1. Lambermont, Bernard

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  2. Lawler, Mark

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  3. Lawrence, Andrew J.

    1. Chronic Antidepressant Treatment Causes a Selective Reduction of μ-Opioid Receptor Binding and Functional Coupling to G Proteins in the Amygdala of Fawn-Hooded Rats
      Feng Chen and Andrew J. Lawrence
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1020-1026; DOI: https://doi.org/10.1124/jpet.104.068692

  4. Lawrence, David C.

    1. Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
      Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay and Robert J. DeLorenzo
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 871-880; DOI: https://doi.org/10.1124/jpet.104.068478

  5. Ledwidge, Susan

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  6. Le Fur, Gérard

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  7. Le Kim, A.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  8. León, Rafael

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  9. Li, Huige

    1. Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
      Huige Li, Ning Xia, Isolde Brausch, Ying Yao and Ulrich Förstermann
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 926-932; DOI: https://doi.org/10.1124/jpet.104.066639

  10. Liang, Jing

    1. Altered Pharmacology of Synaptic and Extrasynaptic GABAA Receptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence
      Jing Liang, Elisabetta Cagetti, Richard W. Olsen and Igor Spigelman
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1234-1245; DOI: https://doi.org/10.1124/jpet.104.067983

  11. Lin, Huimin

    1. Disposition of Flavonoids via Enteric Recycling: Enzyme-Transporter Coupling Affects Metabolism of Biochanin A and Formononetin and Excretion of Their Phase II Conjugates
      Xiaobin Jia, Jun Chen, Huimin Lin and Ming Hu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1103-1113; DOI: https://doi.org/10.1124/jpet.104.068403

  12. Lingenhoehl, Kurt

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  13. Lolivier, J.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  14. López, Manuela G.

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  15. Lou, Zhuangwei

    1. Ligand Dependency of 5-Hydroxytryptamine 2C Receptor Internalization
      Brian D. Schlag, Zhuangwei Lou, Myles Fennell and John Dunlop
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 865-870; DOI: https://doi.org/10.1124/jpet.104.067306

  16. Lupica, Carl R.

    1. Differential Effects of Endogenous and Synthetic Cannabinoids on α7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
      Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales and Carl R. Lupica
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1152-1160; DOI: https://doi.org/10.1124/jpet.104.067751

  17. Lysko, Paul G.

    1. Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
      Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1142-1151; DOI: https://doi.org/10.1124/jpet.104.067314

M

  1. Mabley, Jon G.

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  2. Magis, David

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  3. Makhay, Malath

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  4. Mantey, Samuel A.

    1. Development of Bombesin Analogs with Conformationally Restricted Amino Acid Substitutions with Enhanced Selectivity for the Orphan Receptor Human Bombesin Receptor Subtype 3
      Samuel A. Mantey, David H. Coy, Laurence K. Entsuah and Robert T. Jensen
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1161-1170; DOI: https://doi.org/10.1124/jpet.104.066761

  5. Marc, C.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  6. Marco, Jose L.

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  7. Marszalec, William

    1. Mechanism of Action of Galantamine on N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons
      Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh and Toshio Narahashi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 933-942; DOI: https://doi.org/10.1124/jpet.104.067603

  8. Martinez, Serge

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  9. Maruani, Jeanne

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  10. Matsumoto, Ken-ichiro

    1. Novel Pharmacokinetic Measurement Using Electron Paramagnetic Resonance Spectroscopy and Simulation of in Vivo Decay of Various Nitroxyl Spin Probes in Mouse Blood
      Ken-ichiro Matsumoto, Murali C. Krishna and James B. Mitchell
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1076-1083; DOI: https://doi.org/10.1124/jpet.104.066647

  11. Matsumoto, Shigeji

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  12. Matsuoka, Nobuya

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  13. Matsuura, Shigeru

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  14. McCay, Brendan D.

    1. Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
      Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay and Robert J. DeLorenzo
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 871-880; DOI: https://doi.org/10.1124/jpet.104.068478

  15. Mc Gee, Margaret M.

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  16. Mihara, Kayoko

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  17. Mikheeva, Tatiana

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  18. Millen, Brandie

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  19. Miller, Dennis K.

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

  20. Mitchell, James B.

    1. Novel Pharmacokinetic Measurement Using Electron Paramagnetic Resonance Spectroscopy and Simulation of in Vivo Decay of Various Nitroxyl Spin Probes in Mouse Blood
      Ken-ichiro Matsumoto, Murali C. Krishna and James B. Mitchell
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1076-1083; DOI: https://doi.org/10.1124/jpet.104.066647

  21. Mombereau, Cedric

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  22. Morales, Marisela

    1. Differential Effects of Endogenous and Synthetic Cannabinoids on α7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
      Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales and Carl R. Lupica
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1152-1160; DOI: https://doi.org/10.1124/jpet.104.067751

  23. Mori, Masatomo

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  24. Moriguchi, Shigeki

    1. Mechanism of Action of Galantamine on N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons
      Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh and Toshio Narahashi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 933-942; DOI: https://doi.org/10.1124/jpet.104.067603

  25. Morimont, Philippe

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  26. Muramatsu, Ikunobu

    1. Identification of α-1L Adrenoceptor in Rabbit Ear Artery
      Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki and Ikunobu Muramatsu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 995-1002; DOI: https://doi.org/10.1124/jpet.104.066985

  27. Mussoni, Luciana

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  28. Mutoh, Seitaro

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

N

  1. Nacci, Vito

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  2. Nahorski, Stefan R.

    1. Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
      Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski and R. A. John Challiss
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1255-1265; DOI: https://doi.org/10.1124/jpet.104.067140

  3. Nally, Rachel E.

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  4. Napier, Carolyn M.

    1. Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
      Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski and R. A. John Challiss
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1255-1265; DOI: https://doi.org/10.1124/jpet.104.067140

  5. Narahashi, Toshio

    1. Mechanism of Action of Galantamine on N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons
      Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh and Toshio Narahashi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 933-942; DOI: https://doi.org/10.1124/jpet.104.067603

  6. Navis, Gerjan

    1. Low Sodium Modifies the Vascular Effects of Angiotensin-Converting Enzyme Inhibitor Therapy in Healthy Rats
      Menno J. A. Kocks, Simone Gschwend, Dick de Zeeuw, Gerjan Navis and Hendrik Buikema
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1183-1189; DOI: https://doi.org/10.1124/jpet.104.067272

  7. Naydenova, Zlatina

    1. The Adenosine Transporter, mENT1, Is a Target for Adenosine Receptor Signaling and Protein Kinase Cϵ in Hypoxic and Pharmacological Preconditioning in the Mouse Cardiomyocyte Cell Line, HL-1
      Naz Chaudary, Zlatina Naydenova, Irina Shuralyova and Imogen R. Coe
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1190-1198; DOI: https://doi.org/10.1124/jpet.104.067157

  8. Nelson, Carl P.

    1. Functional Selectivity of Muscarinic Receptor Antagonists for Inhibition of M3-Mediated Phosphoinositide Responses in Guinea Pig Urinary Bladder and Submandibular Salivary Gland
      Carl P. Nelson, Paul Gupta, Carolyn M. Napier, Stefan R. Nahorski and R. A. John Challiss
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1255-1265; DOI: https://doi.org/10.1124/jpet.104.067140

  9. Norrholm, Seth D.

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

  10. Nunez, Derek J. R.

    1. Regional Hemodynamic Effects of the N-(2-Benzoylphenyl)-l-tyrosine Peroxisome Proliferator-Activated Receptor-γ Ligand, GI 262570 [(S)-2-(2-Benzoylphenylamino)-3-[4-[2-(5-methyl-2-phenyl-2-oxazol-4-yl)ethoxy]phenyl]propionic Acid], in Conscious Rats
      Sheila M Gardiner, Derek J. R. Nunez, Philip G. Baer, Kathleen K. Brown and Terence Bennett
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1226-1233; DOI: https://doi.org/10.1124/jpet.104.068817

O

  1. Ohizumi, Yasushi

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

  2. Okada, Shuichi

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  3. Olejar, Kenneth J.

    1. Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
      Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor and Paul C. Dolber
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1266-1272; DOI: https://doi.org/10.1124/jpet.103.063842

  4. Olsen, Richard W.

    1. Altered Pharmacology of Synaptic and Extrasynaptic GABAA Receptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence
      Jing Liang, Elisabetta Cagetti, Richard W. Olsen and Igor Spigelman
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1234-1245; DOI: https://doi.org/10.1124/jpet.104.067983

  5. Ongini, Ennio

    1. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

  6. Orozco, Camilo

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  7. Oustric, Didier

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  8. Oz, Murat

    1. Differential Effects of Endogenous and Synthetic Cannabinoids on α7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
      Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales and Carl R. Lupica
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1152-1160; DOI: https://doi.org/10.1124/jpet.104.067751

P

  1. Padilla-Eagar, J.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  2. Palmieri, S.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  3. Pandini, M.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  4. Papp, Lilla

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

  5. Perego, Carlo

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  6. Pério, Alain

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  7. Perretti, Mauro

    1. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

  8. Perron, C.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  9. Pippig, S.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  10. Poncelet, Martine

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  11. Puech, F.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  12. Pyke, Simon M.

    1. Strong Protein Adduct Trapping Accompanies Abolition of Acrolein-Mediated Hepatotoxicity by Hydralazine in Mice
      Lisa M. Kaminskas, Simon M. Pyke and Philip C. Burcham
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1003-1010; DOI: https://doi.org/10.1124/jpet.104.067330

R

  1. Rae, James M.

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  2. Ravindran, Arippa

    1. Differential Effects of Endogenous and Synthetic Cannabinoids on α7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
      Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales and Carl R. Lupica
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1152-1160; DOI: https://doi.org/10.1124/jpet.104.067751

  3. Ray, Prabhati

    1. Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in Nerve Growth Factor-Treated PC12 Cells
      Hiroshi Ishida, Xieping Zhang, Kelly Erickson and Prabhati Ray
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 881-889; DOI: https://doi.org/10.1124/jpet.104.065318

  4. Reilly, Christopher A.

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  5. Reinhardt, Lindsay E.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  6. Reiter, Jerome P.

    1. Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
      Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor and Paul C. Dolber
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1266-1272; DOI: https://doi.org/10.1124/jpet.103.063842

  7. Reynolds, Jessica L.

    1. Brain-Derived Tumor Necrosis Factor-α and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant
      Jessica L. Reynolds, Tracey A. Ignatowski, Reeteka Sud and Robert N. Spengler
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1216-1225; DOI: https://doi.org/10.1124/jpet.104.067835

  8. Richardson, J. Steven

    1. Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
      Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson and Peter H. Yu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1125-1132; DOI: https://doi.org/10.1124/jpet.104.068601

  9. Rinaldi-Carmona, Murielle

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  10. Rivier, Jean E.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  11. Rizzo, Gianni

    1. Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-κB
      John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato and Stefano Fiorucci
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1096-1102; DOI: https://doi.org/10.1124/jpet.104.067850

  12. Rossi, Francesco

    1. The Distinct Alterations Produced in Cardiovascular Functions by Prednisolone and Nitro-prednisolone (NCX-1015) in the Rat Highlight a Causal Role for Endothelin-1
      Clara Di Filippo, Francesco Rossi, Ennio Ongini, Piero Del Soldato, Mauro Perretti and Michele D'Amico
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1133-1141; DOI: https://doi.org/10.1124/jpet.104.068726

S

  1. Scatton, B.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  2. Schlag, Brian D.

    1. Ligand Dependency of 5-Hydroxytryptamine 2C Receptor Internalization
      Brian D. Schlag, Zhuangwei Lou, Myles Fennell and John Dunlop
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 865-870; DOI: https://doi.org/10.1124/jpet.104.067306

  3. Scott, Gwen S.

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  4. Segers, Patrick

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  5. Sharma, Ashish

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  6. Shen, Danny D.

    1. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
      Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen and Rodney J. Y. Ho
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1199-1207; DOI: https://doi.org/10.1124/jpet.104.065383

  7. Shimizu, Hiroyuki

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  8. Shimomura, Kenju

    1. Fenofibrate, Troglitazone, and 15-Deoxy-Δ12,14-prostaglandin J2 Close KATP Channels and Induce Insulin Secretion
      Kenju Shimomura, Hiroyuki Shimizu, Mizuho Ikeda, Shuichi Okada, Masafumi Kakei, Shigeji Matsumoto and Masatomo Mori
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1273-1280; DOI: https://doi.org/10.1124/jpet.104.067249

  9. Shinkawa, Takashi

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

  10. Shuralyova, Irina

    1. The Adenosine Transporter, mENT1, Is a Target for Adenosine Receptor Signaling and Protein Kinase Cϵ in Hypoxic and Pharmacological Preconditioning in the Mouse Cardiomyocyte Cell Line, HL-1
      Naz Chaudary, Zlatina Naydenova, Irina Shuralyova and Imogen R. Coe
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1190-1198; DOI: https://doi.org/10.1124/jpet.104.067157

  11. Simmonds, Andrea C.

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  12. Sironi, Luigi

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  13. Sombati, Sompong

    1. Epileptogenesis Causes Acute and Chronic Increases in GABAA Receptor Endocytosis That Contributes to the Induction and Maintenance of Seizures in the Hippocampal Culture Model of Acquired Epilepsy
      Robert E. Blair, Sompong Sombati, David C. Lawrence, Brendan D. McCay and Robert J. DeLorenzo
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 871-880; DOI: https://doi.org/10.1124/jpet.104.068478

  14. Son, Thomas

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  15. Sontag, N.

    1. SL25.1131 [3(S),3a(S)-3-Methoxymethyl-7-[4,4,4-trifluorobutoxy]-3,3a,4,5-tetrahydro-1,3-oxazolo[3,4-a]quinolin-1-one], a New, Reversible, and Mixed Inhibitor of Monoamine Oxidase-A and Monoamine Oxidase-B: Biochemical and Behavioral Profile
      N. Aubin, P. Barneoud, C. Carter, D. Caille, N. Sontag, C. Marc, J. Lolivier, A. Gardes, C. Perron, A. Le Kim, T. Charieras, M. Pandini, P. Burnier, F. Puech, S. Jegham, P. George, B. Scatton and O. Curet
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1171-1182; DOI: https://doi.org/10.1124/jpet.103.064782

  16. Soubrié, Philippe

    1. SR147778 [5-(4-Bromophenyl)-1-(2,4-dichlorophenyl)-4-ethyl-N-(1-piperidinyl)-1H-pyrazole-3-carboxamide], a New Potent and Selective Antagonist of the CB1 Cannabinoid Receptor: Biochemical and Pharmacological Characterization
      Murielle Rinaldi-Carmona, Francis Barth, Christian Congy, Serge Martinez, Didier Oustric, Alain Pério, Martine Poncelet, Jeanne Maruani, Michèle Arnone, Olivier Finance, Philippe Soubrié and Gérard Le Fur
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 905-914; DOI: https://doi.org/10.1124/jpet.104.067884

  17. Soukhova, Nadia V.

    1. Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6
      Zeruesenay Desta, Bryan A. Ward, Nadia V. Soukhova and David A. Flockhart
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1062-1075; DOI: https://doi.org/10.1124/jpet.104.065607

  18. Spalding, Tracy A.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  19. Spengler, Robert N.

    1. Brain-Derived Tumor Necrosis Factor-α and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant
      Jessica L. Reynolds, Tracey A. Ignatowski, Reeteka Sud and Robert N. Spengler
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1216-1225; DOI: https://doi.org/10.1124/jpet.104.067835

  20. Sperlágh, Beáta

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

  21. Spigelman, Igor

    1. Altered Pharmacology of Synaptic and Extrasynaptic GABAA Receptors on CA1 Hippocampal Neurons Is Consistent with Subunit Changes in a Model of Alcohol Withdrawal and Dependence
      Jing Liang, Elisabetta Cagetti, Richard W. Olsen and Igor Spigelman
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1234-1245; DOI: https://doi.org/10.1124/jpet.104.067983

  22. Spooren, Will P. J. M.

    1. Behavioral Characterization of the Novel GABAB Receptor-Positive Modulator GS39783 (N,N′-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine): Anxiolytic-Like Activity without Side Effects Associated with Baclofen or Benzodiazepines
      John F. Cryan, Peter H. Kelly, Frederique Chaperon, Conrad Gentsch, Cedric Mombereau, Kurt Lingenhoehl, Wolfgang Froestl, Bernhard Bettler, Klemens Kaupmann and Will P. J. M. Spooren
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 952-963; DOI: https://doi.org/10.1124/jpet.104.066753

  23. Stefanich, E.

    1. In Vitro Internalization, Intracellular Transport, and Clearance of an Anti-CD11a Antibody (Raptiva) by Human T-Cells
      G. P. Coffey, E. Stefanich, S. Palmieri, R. Eckert, J. Padilla-Eagar, P. J. Fielder and S. Pippig
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 896-904; DOI: https://doi.org/10.1124/jpet.104.067611

  24. Sud, Reeteka

    1. Brain-Derived Tumor Necrosis Factor-α and Its Involvement in Noradrenergic Neuron Functioning Involved in the Mechanism of Action of an Antidepressant
      Jessica L. Reynolds, Tracey A. Ignatowski, Reeteka Sud and Robert N. Spengler
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1216-1225; DOI: https://doi.org/10.1124/jpet.104.067835

  25. Suzuki, Fumiko

    1. Identification of α-1L Adrenoceptor in Rabbit Ear Artery
      Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki and Ikunobu Muramatsu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 995-1002; DOI: https://doi.org/10.1124/jpet.104.066985

  26. Szabo, Bela

    1. Analysis of the Effects of Cannabinoids on Synaptic Transmission between Basket and Purkinje Cells in the Cerebellar Cortex of the Rat
      Bela Szabo, Marta Than, David Thorn and Ilka Wallmichrath
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 915-925; DOI: https://doi.org/10.1124/jpet.104.066670

  27. Szabó, Csaba

    1. The Therapeutic Effects of PJ34 [N-(6-Oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a Selective Inhibitor of Poly(ADP-Ribose) Polymerase, in Experimental Allergic Encephalomyelitis Are Associated with Immunomodulation
      Gwen S. Scott, Rhonda B. Kean, Tatiana Mikheeva, Marzena J. Fabis, Jon G. Mabley, Csaba Szabó and D. Craig Hooper
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1053-1061; DOI: https://doi.org/10.1124/jpet.103.063214

  28. Szabó, Gábor

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

T

  1. Tallarida, Ronald J.

    1. Isobolographic Analysis for Combinations of a Full and Partial Agonist: Curved Isoboles
      Yury Grabovsky and Ronald J. Tallarida
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 981-986; DOI: https://doi.org/10.1124/jpet.104.067264

  2. Tanaka, Takashi

    1. Identification of α-1L Adrenoceptor in Rabbit Ear Artery
      Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki and Ikunobu Muramatsu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 995-1002; DOI: https://doi.org/10.1124/jpet.104.066985

  3. Tchana-Sato, Vincent

    1. Effect of BM-573 [N-Terbutyl-N′-[2-(4′-methylphenylamino)-5-nitro-benzenesulfonyl]urea], a Dual Thromboxane Synthase Inhibitor and Thromboxane Receptor Antagonist, in a Porcine Model of Acute Pulmonary Embolism
      Alexandre Ghuysen, Bernard Lambermont, Jean-Michel Dogné, Philippe Kolh, Vincent Tchana-Sato, Philippe Morimont, David Magis, Julien Hanson, Patrick Segers and Vincent D'Orio
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 964-972; DOI: https://doi.org/10.1124/jpet.104.066852

  4. Than, Marta

    1. Analysis of the Effects of Cannabinoids on Synaptic Transmission between Basket and Purkinje Cells in the Cerebellar Cortex of the Rat
      Bela Szabo, Marta Than, David Thorn and Ilka Wallmichrath
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 915-925; DOI: https://doi.org/10.1124/jpet.104.066670

  5. Thor, Karl B.

    1. Inhibition of Bladder Activity by 5-Hydroxytryptamine1 Serotonin Receptor Agonists in Cats with Chronic Spinal Cord Injury
      Baojun Gu, Kenneth J. Olejar, Jerome P. Reiter, Karl B. Thor and Paul C. Dolber
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1266-1272; DOI: https://doi.org/10.1124/jpet.103.063842

  6. Thorn, David

    1. Analysis of the Effects of Cannabinoids on Synaptic Transmission between Basket and Purkinje Cells in the Cerebellar Cortex of the Rat
      Bela Szabo, Marta Than, David Thorn and Ilka Wallmichrath
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 915-925; DOI: https://doi.org/10.1124/jpet.104.066670

  7. Tighe, Orna

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  8. Tolf, Bo-Ragnar

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  9. Tremoli, Elena

    1. Pentoxifylline Prevents Spontaneous Brain Ischemia in Stroke-Prone Rats
      Cristina Banfi, Luigi Sironi, Grazia De Simoni, Paolo Gelosa, Simona Barcella, Carlo Perego, Elisabetta Gianazza, Uliano Guerrini, Elena Tremoli and Luciana Mussoni
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 890-895; DOI: https://doi.org/10.1124/jpet.104.067090

  10. Tsao, Cheng-Chung

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

U

  1. Ueno, Mitsuhiro

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

V

  1. Valdez, Glenn R.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  2. Vale, Wylie W.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676

  3. Vanover, Kimberly E.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  4. Veinbergs, Isaac

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  5. Villarroya, Mercedes

    1. ITH4012 (Ethyl 5-Amino-6,7,8,9-tetrahydro-2-methyl-4-phenylbenzol[1,8]naphthyridine-3-carboxylate), a Novel Acetylcholinesterase Inhibitor with “Calcium Promotor” and Neuroprotective Properties
      Camilo Orozco, Cristobal de los Rios, Esperanza Arias, Rafael León, Antonio G. García, Jose L. Marco, Mercedes Villarroya and Manuela G. López
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 987-994; DOI: https://doi.org/10.1124/jpet.104.068189

  6. Vizi, E. Sylvester

    1. P2X Receptor Activation Elicits Transporter-Mediated Noradrenaline Release from Rat Hippocampal Slices
      Lilla Papp, Tamás Balázsa, Attila Köfalvi, Ferenc Erdélyi, Gábor Szabó, E. Sylvester Vizi and Beáta Sperlágh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 973-980; DOI: https://doi.org/10.1124/jpet.104.066712

W

  1. Waddington, John L.

    1. Ethologically Based Resolution of D2-Like Dopamine Receptor Agonist-versus Antagonist-Induced Behavioral Topography in Dopamine- and Adenosine 3′,5′-Monophosphate-Regulated Phosphoprotein of 32 kDa “Knockout” Mutants Congenic on the C57BL/6 Genetic Background
      Rachel E. Nally, Anthony Kinsella, Orna Tighe, David T. Croke, Allen A. Fienberg, Paul Greengard and John L. Waddington
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1281-1287; DOI: https://doi.org/10.1124/jpet.104.068957

  2. Wallace, John L.

    1. Enhanced Anti-Inflammatory Potency of a Nitric Oxide-Releasing Derivative of Flunisolide: Role of Nuclear Factor-κB
      John L. Wallace, Gianni Rizzo, Giuseppe Cirino, Piero Del Soldato and Stefano Fiorucci
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1096-1102; DOI: https://doi.org/10.1124/jpet.104.067850

  3. Wallmichrath, Ilka

    1. Analysis of the Effects of Cannabinoids on Synaptic Transmission between Basket and Purkinje Cells in the Cerebellar Cortex of the Rat
      Bela Szabo, Marta Than, David Thorn and Ilka Wallmichrath
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 915-925; DOI: https://doi.org/10.1124/jpet.104.066670

  4. Ward, Bryan A.

    1. Comprehensive Evaluation of Tamoxifen Sequential Biotransformation by the Human Cytochrome P450 System in Vitro: Prominent Roles for CYP3A and CYP2D6
      Zeruesenay Desta, Bryan A. Ward, Nadia V. Soukhova and David A. Flockhart
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1062-1075; DOI: https://doi.org/10.1124/jpet.104.065607

  5. Webster, Marie

    1. Metabolism of N,N′,N″-Triethylenethiophosphoramide by CYP2B1 and CYP2B6 Results in the Inactivation of Both Isoforms by Two Distinct Mechanisms
      Erin Harleton, Marie Webster, Namandjé N. Bumpus, Ute M. Kent, James M. Rae and Paul F. Hollenberg
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1011-1019; DOI: https://doi.org/10.1124/jpet.104.069112

  6. Weiner, David M.

    1. Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
      Kimberly E. Vanover, Scott C. Harvey, Thomas Son, Stefania Risso Bradley, Henriette Kold, Malath Makhay, Isaac Veinbergs, Tracy A. Spalding, David M. Weiner, Carl Magnus Andersson, Bo-Ragnar Tolf, Mark R. Brann, Uli Hacksell and Robert E. Davis
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 943-951; DOI: https://doi.org/10.1124/jpet.104.066688

  7. Wilhelm, Clare J.

    1. Effects of Methamphetamine and Lobeline on Vesicular Monoamine and Dopamine Transporter-Mediated Dopamine Release in a Cotransfected Model System
      Clare J. Wilhelm, Robert A. Johnson, Paul G. Lysko, Amy J. Eshleman and Aaron Janowsky
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1142-1151; DOI: https://doi.org/10.1124/jpet.104.067314

  8. Williams, D. Clive

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  9. Woodahl, Erica L.

    1. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
      Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen and Rodney J. Y. Ho
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1199-1207; DOI: https://doi.org/10.1124/jpet.104.065383

X

  1. Xia, Ning

    1. Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
      Huige Li, Ning Xia, Isolde Brausch, Ying Yao and Ulrich Förstermann
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 926-932; DOI: https://doi.org/10.1124/jpet.104.066639

Y

  1. Yamakuni, Tohru

    1. IC101 Induces Apoptosis by Akt Dephosphorylation via an Inhibition of Heat Shock Protein 90-ATP Binding Activity Accompanied by Preventing the Interaction with Akt in L1210 Cells
      Hironori Fujiwara, Tohru Yamakuni, Mitsuhiro Ueno, Masaaki Ishizuka, Takashi Shinkawa, Toshiaki Isobe and Yasushi Ohizumi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1288-1295; DOI: https://doi.org/10.1124/jpet.104.065979

  2. Yamamoto, Hatsumi

    1. Identification of α-1L Adrenoceptor in Rabbit Ear Artery
      Yasuko Hiraizumi-Hiraoka, Takashi Tanaka, Hatsumi Yamamoto, Fumiko Suzuki and Ikunobu Muramatsu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 995-1002; DOI: https://doi.org/10.1124/jpet.104.066985

  3. Yamamoto, Hirofumi

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  4. Yamazaki, Syunji

    1. A New Poly(ADP-Ribose) Polymerase Inhibitor, FR261529 [2-(4-Chlorophenyl)-5-quinoxalinecarboxamide], Ameliorates Methamphetamine-Induced Dopaminergic Neurotoxicity in Mice
      Akinori Iwashita, Kayoko Mihara, Syunji Yamazaki, Shigeru Matsuura, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1114-1124; DOI: https://doi.org/10.1124/jpet.104.068932

  5. Yang, Ziping

    1. Multidrug Resistance Gene G1199A Polymorphism Alters Efflux Transport Activity of P-Glycoprotein
      Erica L. Woodahl, Ziping Yang, Tot Bui, Danny D. Shen and Rodney J. Y. Ho
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1199-1207; DOI: https://doi.org/10.1124/jpet.104.065383

  6. Yao, Ying

    1. Flavonoids from Artichoke (Cynara scolymus L.) Up-Regulate Endothelial-Type Nitric-Oxide Synthase Gene Expression in Human Endothelial Cells
      Huige Li, Ning Xia, Isolde Brausch, Ying Yao and Ulrich Förstermann
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 926-932; DOI: https://doi.org/10.1124/jpet.104.066639

  7. Yeh, Jay Z.

    1. Mechanism of Action of Galantamine on N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons
      Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh and Toshio Narahashi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 933-942; DOI: https://doi.org/10.1124/jpet.104.067603

  8. Yost, Garold S.

    1. Bioactivation of 1,1-Dichloroethylene by CYP2E1 and CYP2F2 in Murine Lung
      Andrea C. Simmonds, Burhan I. Ghanayem, Ashish Sharma, Christopher A. Reilly, Brandie Millen, Garold S. Yost and Poh-Gek Forkert
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 855-864; DOI: https://doi.org/10.1124/jpet.104.068171

  9. Yu, Peter H.

    1. Protein Cross-Linkage Induced by Formaldehyde Derived from Semicarbazide-Sensitive Amine Oxidase-Mediated Deamination of Methylamine
      Diana Gubisne-Haberle, Wayne Hill, Mychaylo Kazachkov, J. Steven Richardson and Peter H. Yu
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1125-1132; DOI: https://doi.org/10.1124/jpet.104.068601

Z

  1. Zeldin, Darryl C.

    1. CYP2C44, a New Murine CYP2C That Metabolizes Arachidonic Acid to Unique Stereospecific Products
      Tracy C. DeLozier, Cheng-Chung Tsao, Sherry J. Coulter, Julie Foley, J. Alyce Bradbury, Darryl C. Zeldin and Joyce A. Goldstein
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 845-854; DOI: https://doi.org/10.1124/jpet.104.067819

  2. Zhang, Li

    1. Differential Effects of Endogenous and Synthetic Cannabinoids on α7-Nicotinic Acetylcholine Receptor-Mediated Responses in Xenopus Oocytes
      Murat Oz, Li Zhang, Arippa Ravindran, Marisela Morales and Carl R. Lupica
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1152-1160; DOI: https://doi.org/10.1124/jpet.104.067751

  3. Zhang, Xieping

    1. Botulinum Toxin Type A Targets RhoB to Inhibit Lysophosphatidic Acid-Stimulated Actin Reorganization and Acetylcholine Release in Nerve Growth Factor-Treated PC12 Cells
      Hiroshi Ishida, Xieping Zhang, Kelly Erickson and Prabhati Ray
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 881-889; DOI: https://doi.org/10.1124/jpet.104.065318

  4. Zhao, Xilong

    1. Mechanism of Action of Galantamine on N-Methyl-d-Aspartate Receptors in Rat Cortical Neurons
      Shigeki Moriguchi, William Marszalec, Xilong Zhao, Jay Z. Yeh and Toshio Narahashi
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 933-942; DOI: https://doi.org/10.1124/jpet.104.067603

  5. Zheng, Guangrong

    1. Lobeline Analogs with Enhanced Affinity and Selectivity for Plasmalemma and Vesicular Monoamine Transporters
      Dennis K. Miller, Peter A. Crooks, Guangrong Zheng, Vladimir P. Grinevich, Seth D. Norrholm and Linda P. Dwoskin
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1035-1045; DOI: https://doi.org/10.1124/jpet.104.068098

  6. Zisterer, Daniela M.

    1. Selective Induction of Apoptosis by the Pyrrolo-1,5-benzoxazepine 7-[{Dimethylcarbamoyl}oxy]-6-(2-naphthyl)pyrrolo-[2,1-d] (1,5)-benzoxazepine (PBOX-6) in Leukemia Cells Occurs via the c-Jun NH2-Terminal Kinase-Dependent Phosphorylation and Inactivation of Bcl-2 and Bcl-XL
      Margaret M. Mc Gee, Lisa M. Greene, Susan Ledwidge, Giuseppe Campiani, Vito Nacci, Mark Lawler, D. Clive Williams and Daniela M. Zisterer
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1084-1095; DOI: https://doi.org/10.1124/jpet.104.067561

  7. Zorrilla, Eric P.

    1. Human Urocortin 2, a Corticotropin-Releasing Factor (CRF)2 Agonist, and Ovine CRF, a CRF1 Agonist, Differentially Alter Feeding and Motor Activity
      Eric P. Zorrilla, Lindsay E. Reinhardt, Glenn R. Valdez, Koki Inoue, Jean E. Rivier, Wylie W. Vale and George F. Koob
      Journal of Pharmacology and Experimental Therapeutics September 2004, 310 (3) 1027-1034; DOI: https://doi.org/10.1124/jpet.104.068676
Back to top

In this issue

Advertisement