Journal of Pharmacology and Experimental Therapeutics: 310 (2)

August 01, 2004; Volume 310,Issue 2

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Genetic Polymorphisms in Human Proton-Dependent Dipeptide Transporter PEPT1: Implications for the Functional Role of Pro⁵⁸⁶
Eric Y. Zhang, Dong-Jing Fu, Youngeen A. Pak, Trent Stewart, Nitai Mukhopadhyay, Steven A. Wrighton and Kathleen M. Hillgren

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 437-445; DOI: https://doi.org/10.1124/jpet.104.065912
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Methylphenidate Is Stereoselectively Hydrolyzed by Human Carboxylesterase CES1A1
Zejin Sun, Daryl J. Murry, Sonal P. Sanghani, Wilhelmina I. Davis, Natalia Y. Kedishvili, Qin Zou, Thomas D. Hurley and William F. Bosron

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 469-476; DOI: https://doi.org/10.1124/jpet.104.067116
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Guggulsterone Activates Multiple Nuclear Receptors and Induces CYP3A Gene Expression through the Pregnane X Receptor
Dan E. Brobst, Xunshan Ding, Katrina L. Creech, Bryan Goodwin, Brian Kelley and Jeff L. Staudinger

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 528-535; DOI: https://doi.org/10.1124/jpet.103.064329
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Metabolism of Thalidomide in Liver Microsomes of Mice, Rabbits, and Humans
Jun Lu, Nuala Helsby, Brian D. Palmer, Malcolm Tingle, Bruce C. Baguley, Philip Kestell and Lai-Ming Ching

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 571-577; DOI: https://doi.org/10.1124/jpet.104.067793
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Abolition of Valproate-Derived Choleresis in the Mrp2 Transporter-Deficient Rat
Andrew W. E. Wright and Ronald G. Dickinson

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 584-588; DOI: https://doi.org/10.1124/jpet.103.064220
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Differential Involvement of Multidrug Resistance-Associated Protein 1 and P-Glycoprotein in Tissue Distribution and Excretion of Grepafloxacin in Mice
Hiroyuki Sasabe, Yukio Kato, Takashi Suzuki, Minoru Itose, Gohachiro Miyamoto and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 648-655; DOI: https://doi.org/10.1124/jpet.104.065201
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UDP-Glucuronosyltransferase (UGT) 2B15 Pharmacogenetics: UGT2B15 D85Y Genotype and Gender Are Major Determinants of Oxazepam Glucuronidation by Human Liver
Michael H. Court, Qin Hao, Soundararajan Krishnaswamy, Tanios Bekaii-Saab, Abdul Al-Rohaimi, Lisa L. von Moltke and David J. Greenblatt

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 656-665; DOI: https://doi.org/10.1124/jpet.104.067660
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Preclinical Pharmacokinetic Properties of the P-Glycoprotein Inhibitor GF120918A (HCl salt of GF120918, 9,10-Dihydro-5-methoxy-9-oxo-N-[4-[2-(1,2,3,4-tetrahydro-6,7-dimethoxy-2-isoquinolinyl)ethyl]phenyl]-4-acridine-carboxamide) in the Mouse, Rat, Dog, and Monkey
Keith W. Ward and Leonard M. Azzarano

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 703-709; DOI: https://doi.org/10.1124/jpet.104.068288
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Hepatic Disposition and Effects of Nitric Oxide Donors: Rapid and Concentration-Dependent Reduction in the Cytochrome P450-Mediated Drug Metabolism in Isolated Perfused Rat Livers
Ragini Vuppugalla and Reza Mehvar

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 718-727; DOI: https://doi.org/10.1124/jpet.104.065557
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Unique Properties of a Renal Sulfotransferase, St1d1, in Dopamine Metabolism
Miki Shimada, Reiko Terazawa, Yoshiteru Kamiyama, Wataru Honma, Kiyoshi Nagata and Yasushi Yamazoe

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 808-814; DOI: https://doi.org/10.1124/jpet.104.065532

CARDIOVASCULAR

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Imidazoline Receptors but Not α₂-Adrenoceptors Are Regulated in Spontaneously Hypertensive Rat Heart by Chronic Moxonidine Treatment
Rouwayda El-Ayoubi, Ahmed Menaouar, Jolanta Gutkowska and Suhayla Mukaddam-Daher

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 446-451; DOI: https://doi.org/10.1124/jpet.104.067595
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Poly(ADP-Ribose) Polymerase Contributes to the Development of Myocardial Infarction in Diabetic Rats and Regulates the Nuclear Translocation of Apoptosis-Inducing Factor
Chun-Yang Xiao, Min Chen, Zsuzsanna Zsengellér and Csaba Szabó

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 498-504; DOI: https://doi.org/10.1124/jpet.104.066803
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The Nitric Oxide-Releasing Naproxen Derivative Displays Cardioprotection in Perfused Rabbit Heart Submitted to Ischemia-Reperfusion
Giuseppe Rossoni, Barbara Manfredi, Piero Del Soldato and Ferruccio Berti

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 555-562; DOI: https://doi.org/10.1124/jpet.104.067397
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Antiarrhythmic Effects of Ranolazine in a Guinea Pig in Vitro Model of Long-QT Syndrome
Lin Wu, John C. Shryock, Yejia Song, Yuan Li, Charles Antzelevitch and Luiz Belardinelli

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 599-605; DOI: https://doi.org/10.1124/jpet.104.066100
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Effects of Heat Shock Protein 70 Activation by Metabolic Inhibition Preconditioning or κ-Opioid Receptor Stimulation on Ca²⁺ Homeostasis in Rat Ventricular Myocytes Subjected to Ischemic Insults
Jing Liu, Kenneth W. L. Kam, Jing-Jun Zhou, Wing-Yi Yan, Mai Chen, Song Wu and Tak Ming Wong

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 606-613; DOI: https://doi.org/10.1124/jpet.104.067926
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Diminished Inotropic Response to Amrinone in Ventricular Myocytes from Myopathic Hamsters Is Linked to Depression of High-Gain Ca²⁺-Induced Ca²⁺ Release
Wei Xiong, Gregory R. Ferrier and Susan E. Howlett

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 761-773; DOI: https://doi.org/10.1124/jpet.103.064873

CELLULAR AND MOLECULAR

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Generation and Characterization of a Human Bradykinin Receptor B1 Transgenic Rat as a Pharmacodynamic Model
J. Fred Hess, Richard W. Ransom, Zhizhen Zeng, Raymond S. L. Chang, Patricia J. Hey, Lee Warren, Charles M. Harrell, Kathryn L. Murphy, Tsing-Bau Chen, Patricia J. Miller, Edward Lis, Duane Reiss, Raymond E. Gibson, M. Kristine Markowitz, Robert M. DiPardo, Dai-Shi Su, Mark G. Bock, Robert J. Gould and Douglas J. Pettibone

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 488-497; DOI: https://doi.org/10.1124/jpet.104.066886
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Regulation of Choline Transporter Surface Expression and Phosphorylation by Protein Kinase C and Protein Phosphatase 1/2A
Jeremiah Gates, Shawn M. Ferguson, Randy D. Blakely and Subbu Apparsundaram

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 536-545; DOI: https://doi.org/10.1124/jpet.104.066795
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Metallothionein Mediates the Level and Activity of Nuclear Factor ΚB in Murine Fibroblasts
Heather L. Butcher, Wendy A. Kennette, Olga Collins, Rudolfs K. Zalups and James Koropatnick

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 589-598; DOI: https://doi.org/10.1124/jpet.104.066126
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Different Regulation of Human δ-Opioid Receptors by SNC-80 [(+)-4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide] and Endogenous Enkephalins
I. Lecoq, N. Marie, Ph. Jauzac and S. Allouche

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 666-677; DOI: https://doi.org/10.1124/jpet.103.063958
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A Rapid in Vitro Screening for Delivery of Peptide-Derived Peptidase Inhibitors as Potential Drug Candidates via Epithelial Peptide Transporters
Martin Foltz, Antje Meyer, Stephan Theis, Hans-Ulrich Demuth and Hannelore Daniel

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 695-702; DOI: https://doi.org/10.1124/jpet.104.066480
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Acetoacetate Activation of Extracellular Signal-Regulated Kinase 1/2 and p38 Mitogen-Activated Protein Kinase in Primary Cultured Rat Hepatocytes: Role of Oxidative Stress
Mohamed A. Abdelmegeed, Sang K. Kim, Kimberley J. Woodcroft and Raymond F. Novak

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 728-736; DOI: https://doi.org/10.1124/jpet.104.066522
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Nonsteroidal Anti-Inflammatory Drugs Potentiate 1-Methyl-4-phenylpyridinium (MPP⁺)-Induced Cell Death by Promoting the Intracellular Accumulation of MPP⁺ in PC12 Cells
Norimitsu Morioka, Kei Kumagai, Katsuya Morita, Shigeo Kitayama and Toshihiro Dohi

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 800-807; DOI: https://doi.org/10.1124/jpet.104.065300

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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Intratumoral NAMI-A Treatment Triggers Metastasis Reduction, Which Correlates to CD44 Regulation and Tumor Infiltrating Lymphocyte Recruitment
Sabrina Pacor, Sonia Zorzet, Moreno Cocchietto, Marina Bacac, Marta Vadori, Claudia Turrin, Barbara Gava, Anna Castellarin and Gianni Sava

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 737-744; DOI: https://doi.org/10.1124/jpet.104.066175
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ABCG2 Mediates Differential Resistance to SN-38 (7-Ethyl-10-hydroxycamptothecin) and Homocamptothecins
Susan E. Bates, Wilma Y. Medina-Pérez, Glenda Kohlhagen, Smitha Antony, Tim Nadjem, Robert W. Robey and Yves Pommier

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 836-842; DOI: https://doi.org/10.1124/jpet.103.063149

ENDOCRINE AND REPRODUCTIVE

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Metformin Causes Reduction of Food Intake and Body Weight Gain and Improvement of Glucose Intolerance in Combination with Dipeptidyl Peptidase IV Inhibitor in Zucker fa/fa Rats
Nobuyuki Yasuda, Takashi Inoue, Tadashi Nagakura, Kazuto Yamazaki, Kazunobu Kira, Takao Saeki and Isao Tanaka

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 614-619; DOI: https://doi.org/10.1124/jpet.103.064964

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Rapid Up-Regulation of Endothelial Nitric-Oxide Synthase in a Mouse Model of Escherichia coli Lipopolysaccharide-Induced Bladder Inflammation
Walter S. Kang, Frank J. Tamarkin, Marcia A. Wheeler and Robert M. Weiss

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 452-458; DOI: https://doi.org/10.1124/jpet.104.066506
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Role of Adenosine A₁ Receptor in the Regulation of Gastrin Release
Linda Yip, Henry Chi Hang Leung and Yin Nam Kwok

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 477-487; DOI: https://doi.org/10.1124/jpet.104.066654
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Disruption of the Ah Receptor Gene Alters the Susceptibility of Mice to Oxygen-Mediated Regulation of Pulmonary and Hepatic Cytochromes P4501A Expression and Exacerbates Hyperoxic Lung Injury
Weiwu Jiang, Stephen E. Welty, Xanthi I. Couroucli, Roberto Barrios, Sudha R. Kondraganti, Kathirvel Muthiah, Ling Yu, Stephen E. Avery and Bhagavatula Moorthy

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 512-519; DOI: https://doi.org/10.1124/jpet.103.059766
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A c-Jun NH₂-Terminal Kinase Inhibitor SP600125 (Anthra[1,9-cd]pyrazole-6 (2H)-one) Blocks Activation of Pancreatic Stellate Cells
Atsushi Masamune, Kazuhiro Kikuta, Noriaki Suzuki, Masahiro Satoh, Kennichi Satoh and Tooru Shimosegawa

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 520-527; DOI: https://doi.org/10.1124/jpet.104.067280
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Induction of Small Intestinal Damage in Rats Following Combined Treatment with Cyclooxygenase-2 and Nitric-Oxide Synthase Inhibitors
Ryoko Ohno, Aya Yokota, Akiko Tanaka and Koji Takeuchi

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 821-827; DOI: https://doi.org/10.1124/jpet.104.065961

INFLAMMATION AND IMMUNOPHARMACOLOGY

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Cyclooxygenases 1, 2, and 3 and the Production of Prostaglandin I₂: Investigating the Activities of Acetaminophen and Cyclooxygenase-2-Selective Inhibitors in Rat Tissues
Timothy D. Warner, Ivana Vojnovic, Francesco Giuliano, Rosario Jiménez, David Bishop-Bailey and Jane A. Mitchell

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 642-647; DOI: https://doi.org/10.1124/jpet.103.063875
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Interleukin-18 Induces Mechanical Hypernociception in Rats via Endothelin Acting on ET_B Receptors in a Morphine-Sensitive Manner
Waldiceu A. Verri, Ieda R. S. Schivo, Thiago M. Cunha, Foo Y. Liew, Sergio H. Ferreira and Fernando Q. Cunha

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 710-717; DOI: https://doi.org/10.1124/jpet.103.063990
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Preferential Inhibition of T Helper 1, but Not T Helper 2, Cytokines in Vitro by L-826,141 [4-{2-(3,4-Bisdifluromethoxyphenyl)-2-{4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-phenyl]-ethyl}-3-methylpyridine-1-oxide], a Potent and Selective Phosphodiesterase 4 Inhibitor
D. Claveau, S. L. Chen, S. O'Keefe, D. M. Zaller, A. Styhler, S. Liu, Z. Huang, D. W. Nicholson and J. A. Mancini

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 752-760; DOI: https://doi.org/10.1124/jpet.103.064691

NEUROPHARMACOLOGY

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A Novel and Potent Poly(ADP-Ribose) Polymerase-1 Inhibitor, FR247304 (5-Chloro-2-[3-(4-phenyl-3,6-dihydro-1(2H)-pyridinyl)propyl]-4(3H)-quinazolinone), Attenuates Neuronal Damage in in Vitro and in Vivo Models of Cerebral Ischemia
Akinori Iwashita, Nobuteru Tojo, Shigeru Matsuura, Syunji Yamazaki, Kazunori Kamijo, Junya Ishida, Hirofumi Yamamoto, Kouji Hattori, Nobuya Matsuoka and Seitaro Mutoh

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 425-436; DOI: https://doi.org/10.1124/jpet.104.066944
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Regulation of Blood-Brain Barrier Na,K,2Cl-Cotransporter through Phosphorylation during in Vitro Stroke Conditions and Nicotine Exposure
Thomas J. Abbruscato, Steve P. Lopez, Karen Roder and Jennifer R. Paulson

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 459-468; DOI: https://doi.org/10.1124/jpet.104.066274
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Differential Activity of the Nerve Growth Factor (NGF) Antagonist PD90780 [7-(Benzolylamino)-4,9-dihydro-4-methyl-9-oxo-pyrazolo[5,1-b]quinazoline-2-carboxylic Acid] Suggests Altered NGF-p75^NTR Interactions in the Presence of TrkA
Amy Colquhoun, Gail M. Lawrance, Igor L. Shamovsky, Richard J. Riopelle and Gregory M. Ross

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 505-511; DOI: https://doi.org/10.1124/jpet.104.066225
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Characterization of Two Novel N-Methyl-D-aspartate Antagonists: EAA-090 (2-[8,9-Dioxo-2,6-diazabicyclo [5.2.0]non-1(7)-en2-yl]ethylphosphonic Acid) and EAB-318 (R-α-Amino-5-chloro-1-(phosphonomethyl)-1H-benzimidazole-2-propanoic Acid Hydrochloride)
Lucy Sun, Doreen Chiu, Dianne Kowal, Rachelle Simon, Michelle Smeyne, R. Suzanne Zukin, John Olney, Reinhardt Baudy and Stephen Lin

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 563-570; DOI: https://doi.org/10.1124/jpet.104.066092
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Effects of the Potential Antidepressant OPC-14523 [1-[3-[4-(3-chlorophenyl)-1-piperazinyl]propyl]-5-methoxy-3,4-dihydro-2-quinolinone Monomethanesulfonate] a Combined σ and 5-HT_1A Ligand: Modulation of Neuronal Activity in the Dorsal Raphe Nucleus
Jordanna E. Bermack, Nasser Haddjeri and Guy Debonnel

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 578-583; DOI: https://doi.org/10.1124/jpet.104.066472
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3-[2-Cyano-3-(trifluoromethyl)phenoxy]phenyl-4,4,4-trifluoro-1-butanesulfonate (BAY 59-3074): A Novel Cannabinoid CB₁/CB₂ Receptor Partial Agonist with Antihyperalgesic and Antiallodynic Effects
Jean De Vry, Dirk Denzer, Elke Reissmueller, Maud Eijckenboom, Markus Heil, Heinrich Meier and Frank Mauler

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 620-632; DOI: https://doi.org/10.1124/jpet.103.062836
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A Guinea Pig Hippocampal Slice Model of Organophosphate-Induced Seizure Activity
Patrick K. Harrison, Robert D. Sheridan, A. Chris Green, Iain R. Scott and John E. H. Tattersall

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 678-686; DOI: https://doi.org/10.1124/jpet.104.065433
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Serotonin 5-HT_2A Receptors Underlie Increased Motor Behaviors Induced in Dopamine-Depleted Rats by Intrastriatal 5-HT2A/2C Agonism
Christopher Bishop, Jennifer L. Tessmer, Thomas Ullrich, Kenner C. Rice and Paul D. Walker

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 687-694; DOI: https://doi.org/10.1124/jpet.104.066365
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Behavior of α-, β-, and γ-Cyclodextrins and Their Derivatives on an in Vitro Model of Blood-Brain Barrier
V. Monnaert, S. Tilloy, H. Bricout, L. Fenart, R. Cecchelli and E. Monflier

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 745-751; DOI: https://doi.org/10.1124/jpet.104.067512
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In Vivo Regulation of Extracellular Signal-Regulated Protein Kinase (ERK) and Protein Kinase B (Akt) Phosphorylation by Acute and Chronic Morphine
Daniella L. Muller and Ellen M. Unterwald

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 774-782; DOI: https://doi.org/10.1124/jpet.104.066548
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DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid), a Novel, Systemically Available, and Peripherally Restricted Mu Opioid Agonist with Antihyperalgesic Activity: I. In Vitro Pharmacological Characterization and Pharmacokinetic Properties
Kenneth J. Valenzano, Wendy Miller, Zhengming Chen, Shen Shan, Gregg Crumley, Sam F. Victory, Ellen Davies, Jin-Cheng Huang, Nezima Allie, Scott J. Nolan, Yakov Rotshteyn, Donald J. Kyle and Kevin Broglé

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 783-792; DOI: https://doi.org/10.1124/jpet.103.063313
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DiPOA ([8-(3,3-Diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic Acid), a Novel, Systemically Available, and Peripherally Restricted Mu Opioid Agonist with Antihyperalgesic Activity: II. In Vivo Pharmacological Characterization in the Rat
Garth T. Whiteside, James E. Harrison, Michelle S. Pearson, Zhengming Chen, Yakov Rotshteyn, Paul I. Turchin, James D. Pomonis, Lilly Mark, Katharine Walker and Kevin C. Broglé

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 793-799; DOI: https://doi.org/10.1124/jpet.103.063560
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Inorganic Lead Exposure in the Rat Activates Striatal cFOS Expression at Lower Blood Levels and Inhibits Amphetamine-Induced cFOS Expression at Higher Blood Levels
Mark W. Lewis and David K. Pitts

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 815-820; DOI: https://doi.org/10.1124/jpet.103.063941
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A Pulmonary Formulation of l-Dopa Enhances Its Effectiveness in a Rat Model of Parkinson's Disease
Raymond T. Bartus, Dwaine Emerich, Pam Snodgrass-Belt, Karen Fu, Heather Salzberg-Brenhouse, Denise Lafreniere, Leah Novak, Ee-Sing Lo, Thomas Cooper and Anthony S. Basile

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 828-835; DOI: https://doi.org/10.1124/jpet.103.064121

TOXICOLOGY

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Site-Specific Metabolism of Naphthalene and 1-Nitronaphthalene in Dissected Airways of Rhesus Macaques
Bridget Boland, Ching Yu Lin, Dexter Morin, Lisa Miller, Charles Plopper and Alan Buckpitt

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 546-554; DOI: https://doi.org/10.1124/jpet.103.063669
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Structural Features of the Botulinum Neurotoxin Molecule That Govern Binding and Transcytosis across Polarized Human Intestinal Epithelial Cells
Andrew B. Maksymowych and Lance L. Simpson

Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 633-641; DOI: https://doi.org/10.1124/jpet.104.066845

Errata

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Correction to “Effects of Alcohols and Anesthetics on Recombinant Voltage-Gated Na⁺ Channels”
Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 843;
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Correction to “Pharmacokinetics and Biodistribution of the Antitumor Immunoconjugate, Cantuzumab Mertansine (huC242-DM1), and Its Two Components in Mice”
Journal of Pharmacology and Experimental Therapeutics August 2004, 310 (2) 844;

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Table of Contents

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

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