Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line

Exploratory Medicinal Sciences (J.B.M, S.M.F.de M.), Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut; and Department of Pharmacokinetics, Dynamics, and Metabolism (K.A.R., N.S., J.S.), Pfizer Global Research and Development, Ann Arbor Laboratories, Ann Arbor, Michigan

Address correspondence to:
Dr. Sonia M. F. de Morais, Pfizer Global Research and Development, Groton Laboratories, Eastern Point Rd., Groton, CT 06340. E-mail: demoraissm{at}groton.pfizer.com

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