Journal of Pharmacology and Experimental Therapeutics: 309 (1)

April 01, 2004; Volume 309,Issue 1

PERSPECTIVES IN PHARMACOLOGY

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Brain Stimulation for Neurological and Psychiatric Disorders, Current Status and Future Direction
Jing-Yu Chang

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 1-7; DOI: https://doi.org/10.1124/jpet.103.049718

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

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Transport of Ethinylestradiol Glucuronide and Ethinylestradiol Sulfate by the Multidrug Resistance Proteins MRP1, MRP2, and MRP3
Xiao-Yan Chu, Su-E. W. Huskey, Matthew P. Braun, Balazs Sarkadi, David C. Evans and Raymond Evers

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 156-164; DOI: https://doi.org/10.1124/jpet.103.062091
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Quantitative Evaluation of the Drug-Drug Interactions between Methotrexate and Nonsteroidal Anti-Inflammatory Drugs in the Renal Uptake Process Based on the Contribution of Organic Anion Transporters and Reduced Folate Carrier
Yoshitane Nozaki, Hiroyuki Kusuhara, Hitoshi Endou and Yuichi Sugiyama

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 226-234; DOI: https://doi.org/10.1124/jpet.103.061812
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Neutral and Anionic Liposome-Encapsulated Hemoglobin: Effect of Postinserted Poly(ethylene glycol)-distearoylphosphatidylethanolamine on Distribution and Circulation Kinetics
V. D. Awasthi, D. Garcia, R. Klipper, B. A. Goins and W. T. Phillips

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 241-248; DOI: https://doi.org/10.1124/jpet.103.060228
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Induction of Drug Metabolism Enzymes and MDR1 Using a Novel Human Hepatocyte Cell Line
Jessica B. Mills, Kelly A. Rose, Nalini Sadagopan, Jasminder Sahi and Sonia M. F. de Morais

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 303-309; DOI: https://doi.org/10.1124/jpet.103.061713

BEHAVIORAL PHARMACOLOGY

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Differential Effects of Δ⁹-Tetrahydrocannabinol and Methanandamide in CB1 Knockout and Wild-Type Mice
Cassandra Y. Baskfield, Billy R. Martin and Jenny L. Wiley

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 86-91; DOI: https://doi.org/10.1124/jpet.103.055376
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Histogranin-Like Antinociceptive and Anti-Inflammatory Derivatives of o-Phenylenediamine and Benzimidazole
Hoang-Thanh Le, Irma B. Lemaire, Annie-Kim Gilbert, François Jolicoeur, Lin Yang, Natacha Leduc and Simon Lemaire

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 146-155; DOI: https://doi.org/10.1124/jpet.103.060772
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δ-Opioid Agonists: Differential Efficacy and Potency of SNC80, Its 3-OH (SNC86) and 3-Desoxy (SNC162) Derivatives in Sprague-Dawley Rats
Emily M. Jutkiewicz, Erik B. Eller, John E. Folk, Kenner C. Rice, John R. Traynor and James H. Woods

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 173-181; DOI: https://doi.org/10.1124/jpet.103.061242
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Estrogen and Progesterone Prevent Disruption of Prepulse Inhibition by the Serotonin-1A Receptor Agonist 8-Hydroxy-2-dipropylaminotetralin
Andrea Gogos and Maarten Van den Buuse

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 267-274; DOI: https://doi.org/10.1124/jpet.103.061432
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Anxiolytic-Like Effects of the Corticotropin-Releasing Factor₁ (CRF₁) Antagonist DMP904 [4-(3-pentylamino)-2,7-dimethyl-8-(2-methyl-4-methoxyphenyl)-pyrazolo-[1,5-a]-pyrimidine] Administered Acutely or Chronically at Doses Occupying Central CRF₁ Receptors in Rats
Snjezana Lelas, Harvey Wong, Yu-Wen Li, Karen L. Heman, Kathryn A. Ward, Kim L. Zeller, Kristine K. Sieracki, Joseph L. Polino, Helen E. Godonis, Shelly X. Ren, Xiao-Xin Yan, Stephen P. Arneric, David W. Robertson, Paul R. Hartig, Scott Grossman, George L. Trainor, Rebecca A. Taub, Robert Zaczek, Paul J. Gilligan and John F. McElroy

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 293-302; DOI: https://doi.org/10.1124/jpet.103.058784
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Novel 2′,6′-Dimethyl-l-Tyrosine-Containing Pyrazinone Opioid Mimetic μ-Agonists with Potent Antinociceptive Activity in Mice
Yunden Jinsmaa, Yoshio Okada, Yuko Tsuda, Kimitaka Shiotani, Yusuke Sasaki, Akihiro Ambo, Sharon D. Bryant and Lawrence H. Lazarus

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 432-438; DOI: https://doi.org/10.1124/jpet.103.060061

CARDIOVASCULAR

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Estrogen Reduces Cardiac Injury and Expression of β₁-Adrenoceptor upon Ischemic Insult in the Rat Heart
Kenneth W. L. Kam, Jian Song Qi, Mai Chen and Tak Ming Wong

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 8-15; DOI: https://doi.org/10.1124/jpet.103.058339
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Role of Neuronal K_ATP Channels and Extraneuronal Monoamine Transporter on Norepinephrine Overflow in a Model of Myocardial Low Flow Ischemia
Christof Burgdorf, Andreas Dendorfer, Thomas Kurz, Edgar Schömig, Ines Stölting, Frank Schütte and Gert Richardt

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 42-48; DOI: https://doi.org/10.1124/jpet.103.059832
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Role of α-Adrenergic Receptors in the Effect of the β-Adrenergic Receptor Ligands, CGP 12177, Bupranolol, and SR 59230A, on the Contraction of Rat Intrapulmonary Artery
Véronique Leblais, Fabrice Pourageaud, M. Dolores Ivorra, Christelle Guibert, Roger Marthan and Bernard Muller

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 137-145; DOI: https://doi.org/10.1124/jpet.103.061192
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Characterization of the Contractile 5-Hydroxytryptamine Receptor in the Renal Artery of the Normotensive Rat
Stephanie W. Watts and Janice M. Thompson

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 165-172; DOI: https://doi.org/10.1124/jpet.103.062562
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Effects of a Novel Cardioselective ATP-Sensitive Potassium Channel Antagonist, 1-[[5-[2-(5-Chloro-o-anisamido)ethyl]-β-methoxyethoxyphenyl]sulfonyl]-3-methylthiourea, Sodium Salt (HMR 1402), on Susceptibility to Ventricular Fibrillation Induced by Myocardial Ischemia: In Vitro and in Vivo Studies
George E. Billman, Melanie S. Houle, Heinrich C. Englert and Heinz Gögelein

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 182-192; DOI: https://doi.org/10.1124/jpet.103.061416
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Effects of SanOrg123781A, a Synthetic Hexadecasaccharide, in a Mouse Model of Electrically Induced Carotid Artery Injury: Synergism with the Antiplatelet Agent Clopidogrel
Janine Lorrain, Irène Lechaire, Christiane Gauffeny, Régis Masson, Nigel Roome, Jean-Pascal Herault, Stephen Eric O'Connor, Paul Schaeffer and Jean-Marc Herbert

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 235-240; DOI: https://doi.org/10.1124/jpet.103.059873
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Novel Dual Action AT₁ and ET_A Receptor Antagonists Reduce Blood Pressure in Experimental Hypertension
Mark C. Kowala, Natesan Murugesan, John Tellew, Kenneth Carlson, Hossain Monshizadegan, Carol Ryan, Zhengxiang Gu, Bridgette Kane, Leena Fadnis, Rose Ann Baska, Sophie Beyer, Susan Arthur, Kenneth Dickinson, Donglu Zhang, Mark Perrone, Pam Ferrer, Mary Giancarli, Jergen Baumann, Eileen Bird, Balkrushna Panchal, Yifan Yang, Nick Trippodo, Joel Barrish and John E. Macor

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 275-284; DOI: https://doi.org/10.1124/jpet.103.055855

CELLULAR AND MOLECULAR

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Polyphenolic Antioxidants Mimic the Effects of 1,4-Dihydropyridines on Neurotensin Receptor Function in PC3 Cells
Robert E. Carraway, Sazzad Hassan and David E. Cochrane

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 92-101; DOI: https://doi.org/10.1124/jpet.103.060442
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NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-Benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride]: A New Selective Inhibitor of T-Type Calcium Channels
Luping Huang, Brian M. Keyser, Tina M. Tagmose, J. Bondo Hansen, James T. Taylor, Hean Zhuang, Min Zhang, David S. Ragsdale and Ming Li

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 193-199; DOI: https://doi.org/10.1124/jpet.103.060814
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Imatinib-Mesylate Blocks Recombinant T-Type Calcium Channels Expressed in Human Embryonic Kidney-293 Cells by a Protein Tyrosine Kinase-Independent Mechanism
Mauro Cataldi, Annarita Gaudino, Vincenzo Lariccia, Michela Russo, Salvatore Amoroso, Gianfranco di Renzo and Lucio Annunziato

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 208-215; DOI: https://doi.org/10.1124/jpet.103.061184
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Pharmacological Characterization and Cross Talk of α_1A- and α_1B-Adrenoceptors Coexpressed in Human Embryonic Kidney 293 Cells
Malika Israilova, Takashi Tanaka, Fumiko Suzuki, Shigeru Morishima and Ikunobu Muramatsu

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 259-266; DOI: https://doi.org/10.1124/jpet.103.061796
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Inhibition of Oxidant-Induced Nuclear Factor-κB Activation and Inhibitory-κBα Degradation and Instability of F-Actin Cytoskeletal Dynamics and Barrier Function by Epidermal Growth Factor: Key Role of Phospholipase-γ Isoform
A. Banan, L. J. Zhang, M. Shaikh, J. Z. Fields, A. Farhadi and A. Keshavarzian

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 356-368; DOI: https://doi.org/10.1124/jpet.103.062232
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The N Terminus of the Human α_1D-Adrenergic Receptor Prevents Cell Surface Expression
Chris Hague, Zhongjian Chen, Andre S. Pupo, Nancy A. Schulte, Myron L. Toews and Kenneth P. Minneman

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 388-397; DOI: https://doi.org/10.1124/jpet.103.060509
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AT₂ Receptors Attenuate AT₁ Receptor-Induced Phospholipase D Activation in Vascular Smooth Muscle Cells
Bradley T. Andresen, Guillermo G. Romero and Edwin K. Jackson

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 425-431; DOI: https://doi.org/10.1124/jpet.103.061846

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

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NAD(P)H:Quinone Oxidoreductase-1-Dependent and -Independent Cytotoxicity of Potent Quinone Cdc25 Phosphatase Inhibitors
Yusheng Han, Hongmei Shen, Brian I. Carr, Peter Wipf, John S. Lazo and Su-shu Pan

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 64-70; DOI: https://doi.org/10.1124/jpet.103.059477
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Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-Based Inhibitors of Human N-Myristoyltransferase-1
Kevin J. French, Yan Zhuang, Randy S. Schrecengost, Jean E. Copper, Zuping Xia and Charles D. Smith

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 340-347; DOI: https://doi.org/10.1124/jpet.103.061572

ENDOCRINE AND REPRODUCTIVE

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Novel and Selective Small Molecule Stimulators of Osteoprotegerin Expression Inhibit Bone Resorption
Jude E. Onyia, Rachelle J. Sells Galvin, Yanfei L. Ma, David L. Halladay, Rebecca R. Miles, Xuhao Yang, Tina Fuson, Ricky L. Cain, Qing Qiang Zeng, S. Chandrasekhar, Renee Emkey, Yanping Xu, Kannan Thirunavukkarasu, Henry U. Bryant and T. John Martin

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 369-379; DOI: https://doi.org/10.1124/jpet.103.057893
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SSR126768A (4-Chloro-3-[(3R)-(+)-5-chloro-1-(2,4-dimethoxybenzyl)-3-methyl-2- oxo-2,3-dihydro-1H-indol-3-yl]-N-ethyl-N-(3-pyridylmethyl)-benzamide, Hydrochloride): A New Selective and Orally Active Oxytocin Receptor Antagonist for the Prevention of Preterm Labor
Claudine Serradeil-Le Gal, Gérard Valette, Loïc Foulon, Guy Germain, Charles Advenier, Emmanuel Naline, Marc Bardou, Jean-Pierre Martinolle, Brigitte Pouzet, Danielle Raufaste, Corinne Garcia, Eléonore Double-Cazanave, Maxime Pauly, Marc Pascal, Alain Barbier, Bernard Scatton, Jean-Pierre Maffrand and Gérard Le Fur

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 414-424; DOI: https://doi.org/10.1124/jpet.103.061200

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

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Transport of Pharmacologically Active Proline Derivatives by the Human Proton-Coupled Amino Acid Transporter hPAT1
Linda Metzner, Jutta Kalbitz and Matthias Brandsch

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 28-35; DOI: https://doi.org/10.1124/jpet.103.059014
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Metabotropic Signal Transduction for Bradykinin in Submucosal Neurons of Guinea Pig Small Intestine
Hong-Zhen Hu, Na Gao, Sumei Liu, Jun Ren, Yun Xia and Jackie D. Wood

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 310-319; DOI: https://doi.org/10.1124/jpet.103.059204
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Action of Bradykinin in the Submucosal Plexus of Guinea Pig Small Intestine
Hong-Zhen Hu, Na Gao, Sumei Liu, Jun Ren, Xiyu Wang, Yun Xia and Jackie D. Wood

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 320-327; DOI: https://doi.org/10.1124/jpet.103.059188

INFLAMMATION AND IMMUNOPHARMACOLOGY

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2,3,7,8-Tetrachlorodibenzo-p-dioxin, an Exogenous Modulator of the 3′α Immunoglobulin Heavy Chain Enhancer in the CH12.LX Mouse Cell Line
Courtney E. W. Sulentic, Wei Zhang, Yong Joo Na and Norbert E. Kaminski

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 71-78; DOI: https://doi.org/10.1124/jpet.103.059493
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Inverse Agonist Activity of Selected Ligands of the Cysteinyl-Leukotriene Receptor 1
Denis J. Dupré, Christian Le Gouill, Denis Gingras, Marek Rola-Pleszczynski and Jana Staňková

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 102-108; DOI: https://doi.org/10.1124/jpet.103.059824
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Inhibitors of Tryptase as Mast Cell-Stabilizing Agents in the Human Airways: Effects of Tryptase and Other Agonists of Proteinase-Activated Receptor 2 on Histamine Release
Shaoheng He, Akhmed Aslam, Marianna D. A. Gaça, Yongsong He, Mark G. Buckley, Morley D. Hollenberg and Andrew F. Walls

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 119-126; DOI: https://doi.org/10.1124/jpet.103.061291
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In Vitro and in Vivo Anti-Inflammatory Activity of the New Glucocorticoid Ciclesonide
Michael Stoeck, Richard Riedel, Günther Hochhaus, Dietrich Häfner, José M. Masso, Beate Schmidt, Armin Hatzelmann, Degenhard Marx and Daniela S. Bundschuh

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 249-258; DOI: https://doi.org/10.1124/jpet.103.059592
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Paroxetine Inhibits Acute Effects of 3,4-Methylenedioxymethamphetamine on the Immune System in Humans
Roberta Pacifici, Simona Pichini, Piergiorgio Zuccaro, Magí Farré, Mireia Segura, Jordi Ortuño, Simonetta Di Carlo, Antonella Bacosi, Pere N. Roset, Jordi Segura and Rafael de la Torre

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 285-292; DOI: https://doi.org/10.1124/jpet.103.061374
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Receptor/Gene-Mediated Pharmacodynamic Effects of Methylprednisolone on Phosphoenolpyruvate Carboxykinase Regulation in Rat Liver
Jin Y. Jin, Debra C. DuBois, Richard R. Almon and William J. Jusko

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 328-339; DOI: https://doi.org/10.1124/jpet.103.061515
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Identification and Characterization of 4-[[4-(2-Butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a Novel Dual Tumor Necrosis Factor-α-Converting Enzyme/Matrix Metalloprotease Inhibitor for the Treatment of Rheumatoid Arthritis
Yuhua Zhang, Jun Xu, Jeremy Levin, Martin Hegen, Guangde Li, Heidi Robertshaw, Fionula Brennan, Terri Cummons, Dave Clarke, Nichole Vansell, Cheryl Nickerson-Nutter, Dauphine Barone, Ken Mohler, Roy Black, Jerry Skotnicki, Jay Gibbons, Marc Feldmann, Philip Frost, Glenn Larsen and Lih-Ling Lin

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 348-355; DOI: https://doi.org/10.1124/jpet.103.059675
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Suppression of 15-Hydroxyprostaglandin Dehydrogenase Messenger RNA Concentration, Protein Expression, and Enzymatic Activity during Human Ureteral Obstruction
Travis J. Jerde, William S. Mellon, Susan M. Fischer, Monica Liebert, Dale E. Bjorling and Stephen Y. Nakada

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 398-403; DOI: https://doi.org/10.1124/jpet.103.056929
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A Potent and Selective Histamine H₄ Receptor Antagonist with Anti-Inflammatory Properties
Robin L. Thurmond, Pragnya J. Desai, Paul J. Dunford, Wai-Ping Fung-Leung, Claudia L. Hofstra, Wen Jiang, Steven Nguyen, Jason P. Riley, Siquan Sun, Kacy N. Williams, James P. Edwards and Lars Karlsson

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 404-413; DOI: https://doi.org/10.1124/jpet.103.061754

NEUROPHARMACOLOGY

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The Neuroprotective Effect of 2-(3-Pyridyl)-1-azabicyclo[3.2.2]nonane (TC-1698), a Novel α7 Ligand, Is Prevented through Angiotensin II Activation of a Tyrosine Phosphatase
Mario B. Marrero, Roger L. Papke, Balwinder S. Bhatti, Seán Shaw and Merouane Bencherif

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 16-27; DOI: https://doi.org/10.1124/jpet.103.061655
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Suppression of Acute Herpetic Pain-Related Responses by the κ-Opioid Receptor Agonist (-)-17-Cyclopropylmethyl-3,14β-dihydroxy-4,5α-epoxy-6β-[N-methyl-3-trans-3-(3-furyl) Acrylamido] Morphinan Hydrochloride (TRK-820) in Mice
Ichiro Takasaki, Tomohiko Suzuki, Atsushi Sasaki, Kaoru Nakao, Mikito Hirakata, Kiyoshi Okano, Toshiaki Tanaka, Hiroshi Nagase, Kimiyasu Shiraki, Hiroshi Nojima and Yasushi Kuraishi

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 36-41; DOI: https://doi.org/10.1124/jpet.103.059816
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Studies of Aβ Pharmacodynamics in the Brain, Cerebrospinal Fluid, and Plasma in Young (Plaque-Free) Tg2576 Mice Using the γ-Secretase Inhibitor N²-[(2S)-2-(3,5-Difluorophenyl)-2-hydroxyethanoyl]-N¹-[(7S)-5-methyl-6-oxo-6,7-dihydro-5H-dibenzo[b,d]azepin-7-yl]-L-alaninamide (LY-411575)
Thomas A. Lanz, John D. Hosley, Wade J. Adams and Kalpana M. Merchant

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 49-55; DOI: https://doi.org/10.1124/jpet.103.060715
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Anandamide Is Able to Inhibit Trigeminal Neurons Using an in Vivo Model of Trigeminovascular-Mediated Nociception
S. Akerman, H. Kaube and P. J. Goadsby

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 56-63; DOI: https://doi.org/10.1124/jpet.103.059808
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Stimulation of Serotonin_2C Receptors Blocks the Hyperactivation of Midbrain Dopamine Neurons Induced by Nicotine Administration
Massimo Pierucci, Vincenzo Di Matteo and Ennio Esposito

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 109-118; DOI: https://doi.org/10.1124/jpet.103.062208
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The Cognition-Enhancer Nefiracetam Inhibits Both Necrosis and Apoptosis in Retinal Ischemic Models in Vitro and in Vivo
Mutsumi Ueda, Ryousuke Fujita, Takehiko Koji and Hiroshi Ueda

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 200-207; DOI: https://doi.org/10.1124/jpet.103.061127
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Ethanol Drinking and Deprivation Alter Dopaminergic and Serotonergic Function in the Nucleus Accumbens of Alcohol-Preferring Rats
R. J. Thielen, E. A. Engleman, Z. A. Rodd, J. M. Murphy, L. Lumeng, T.-K. Li and W. J. McBride

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 216-225; DOI: https://doi.org/10.1124/jpet.103.059790
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Loss of Peripheral Morphine Analgesia Contributes to the Reduced Effectiveness of Systemic Morphine in Neuropathic Pain
Md Harunor Rashid, Makoto Inoue, Kazuo Toda and Hiroshi Ueda

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 380-387; DOI: https://doi.org/10.1124/jpet.103.060582

TOXICOLOGY

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Primaquine-Induced Hemolytic Anemia: Susceptibility of Normal versus Glutathione-Depleted Rat Erythrocytes to 5-Hydroxyprimaquine
Zachary S. Bowman, John E. Oatis, Jennifer L. Whelan, David J. Jollow and David C. McMillan

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 79-85; DOI: https://doi.org/10.1124/jpet.103.062984
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Comparison of Pulmonary/Nasal CYP2F Expression Levels in Rodents and Rhesus Macaque
R. Michael Baldwin, William T. Jewell, Michelle V. Fanucchi, Charles G. Plopper and Alan R. Buckpitt

Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 127-136; DOI: https://doi.org/10.1124/jpet.103.062901

Errata

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Correction to “Sites of Excitatory and Inhibitory Actions of Alcohols on Neuronal α2β4 Nicotinic Acetylcholine Receptors”
Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 439;
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Correction to “Human Hepatic CYP2E1 Expression during Development”
Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 439;
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Correction to “Ca²⁺ Channel Blockers Enhance Neurotensin (NT) Binding and Inhibit NT-Induced Inositol Phosphate Formation in Prostate Cancer PC3 Cells”
Journal of Pharmacology and Experimental Therapeutics April 2004, 309 (1) 439;

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Table of Contents

PERSPECTIVES IN PHARMACOLOGY

ABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

BEHAVIORAL PHARMACOLOGY

CARDIOVASCULAR

CELLULAR AND MOLECULAR

CHEMOTHERAPY, ANTIBIOTICS, AND GENE THERAPY

ENDOCRINE AND REPRODUCTIVE

GASTROINTESTINAL, HEPATIC, PULMONARY, AND RENAL

INFLAMMATION AND IMMUNOPHARMACOLOGY

NEUROPHARMACOLOGY

TOXICOLOGY

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