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Research ArticleNEUROPHARMACOLOGY

Activation of G-Proteins by Morphine and Codeine Congeners: Insights to the Relevance of O- and N-Demethylated Metabolites at μ- and δ-Opioid Receptors

Chad M. Thompson, Heidi Wojno, Elisabeth Greiner, Everette L. May, Kenner C. Rice and Dana E. Selley
Journal of Pharmacology and Experimental Therapeutics February 2004, 308 (2) 547-554; DOI: https://doi.org/10.1124/jpet.103.058602
Chad M. Thompson
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Heidi Wojno
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Elisabeth Greiner
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Everette L. May
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Kenner C. Rice
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Dana E. Selley
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Article Information

vol. 308 no. 2 547-554
DOI 
https://doi.org/10.1124/jpet.103.058602
PubMed 
14600248

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received August 15, 2003
  • Accepted October 29, 2003
  • Published online January 27, 2004.

Article Versions

  • Earlier version (November 4, 2003 - 14:53).
  • You are viewing the most recent version of this article.
Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Chad M. Thompson,
  2. Heidi Wojno,
  3. Elisabeth Greiner,
  4. Everette L. May,
  5. Kenner C. Rice and
  6. Dana E. Selley
  1. Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies (C.M.T., H.W., E.L.M., D.E.S.), Virginia Commonwealth University, Medical College of Virginia, Richmond, Virginia; and Laboratory of Medicinal Chemistry (E.G., K.C.R.), National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland
  1. Address correspondence to:
    Dr. Dana E. Selley, Department of Pharmacology and Toxicology and Institute for Drug and Alcohol Studies, Virginia Commonwealth University, Medical College of Virginia, Box 980524, 1112 East Clay Street, Richmond, VA 23298-0524. E-mail: deselley{at}hsc.vcu.edu
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Journal of Pharmacology and Experimental Therapeutics: 308 (2)
Journal of Pharmacology and Experimental Therapeutics
Vol. 308, Issue 2
1 Feb 2004
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Research ArticleNEUROPHARMACOLOGY

Activation of G-Proteins by Morphine and Codeine Congeners: Insights to the Relevance of O- and N-Demethylated Metabolites at μ- and δ-Opioid Receptors

Chad M. Thompson, Heidi Wojno, Elisabeth Greiner, Everette L. May, Kenner C. Rice and Dana E. Selley
Journal of Pharmacology and Experimental Therapeutics February 1, 2004, 308 (2) 547-554; DOI: https://doi.org/10.1124/jpet.103.058602

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Research ArticleNEUROPHARMACOLOGY

Activation of G-Proteins by Morphine and Codeine Congeners: Insights to the Relevance of O- and N-Demethylated Metabolites at μ- and δ-Opioid Receptors

Chad M. Thompson, Heidi Wojno, Elisabeth Greiner, Everette L. May, Kenner C. Rice and Dana E. Selley
Journal of Pharmacology and Experimental Therapeutics February 1, 2004, 308 (2) 547-554; DOI: https://doi.org/10.1124/jpet.103.058602
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