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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Effect of Interferon-γ on the Pharmacokinetics of Digoxin, a P-glycoprotein Substrate, Intravenously Injected into the Mouse

Hiroko Kawaguchi, Yumi Matsui, Yoshihiko Watanabe and Yoshinobu Takakura
Journal of Pharmacology and Experimental Therapeutics January 2004, 308 (1) 91-96; DOI: https://doi.org/10.1124/jpet.103.057521

Article Information

vol. 308 no. 1 91-96
DOI 
https://doi.org/10.1124/jpet.103.057521
PubMed 
14569074
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0022-3565
Online ISSN 
1521-0103
History 
  • Received July 26, 2003
  • Accepted September 30, 2003
  • Published online January 7, 2004.

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Copyright & Usage 
The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Hiroko Kawaguchi,
  2. Yumi Matsui,
  3. Yoshihiko Watanabe and
  4. Yoshinobu Takakura
  1. Department of Biopharmaceutics and Drug Metabolism (H.K., Y.M., Y.T.) and Department of Molecular Microbiology (Y.W.), Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto, Japan
  1. Address correspondence to:
    Dr. Yoshinobu Takakura, Department of Drug Metabolism and Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Kyoto University, Sakyo-ku, Kyoto 606-8501, Japan. E-mail: takakura{at}pharm.kyoto-u.ac.jp
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Research ArticleABSORPTION, DISTRIBUTION, METABOLISM, AND EXCRETION

Effect of Interferon-γ on the Pharmacokinetics of Digoxin, a P-glycoprotein Substrate, Intravenously Injected into the Mouse

Hiroko Kawaguchi, Yumi Matsui, Yoshihiko Watanabe and Yoshinobu Takakura
Journal of Pharmacology and Experimental Therapeutics January 1, 2004, 308 (1) 91-96; DOI: https://doi.org/10.1124/jpet.103.057521
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